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Search results 1 to 100 out of 844 for Lmx1a

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Type Details Score
Gene
key_980007 | Lmx1a
Type: gene
Organism: Not Specified
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Gene
4009 | LMX1A
Type: gene
Organism: human
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Gene
747979 | LMX1A
Type: gene
Organism: chimpanzee
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Gene
510296 | LMX1A
Type: gene
Organism: cattle
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Gene
777133 | LMX1A
Type: gene
Organism: chicken
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Gene
558036 | lmx1a
Type: gene
Organism: zebrafish
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Gene
694542 | LMX1A
Type: gene
Organism: macaque, rhesus
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Gene
100492433 | lmx1a
Type: gene
Organism: frog, western clawed
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Gene
key_47835 | LMX1A
Type: gene
Organism: hamster, golden
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Gene
289201 | Lmx1a
Type: gene
Organism: rat
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Gene
609061 | LMX1A
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:1888519 | Lmx1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
102725140 | LMX1A-AS1
Type: gene
Organism: human
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Gene
105371561 | LMX1A-AS2
Type: gene
Organism: human
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Publication
19741143 | J:152673
First Author: Mishima Y
Year: 2009
Journal: J Neurosci
Title: Overlapping function of Lmx1a and Lmx1b in anterior hindbrain roof plate formation and cerebellar growth.
Volume: 29
Issue: 36
Pages: 11377-84
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Publication
20498066 | J:161290
First Author: Chizhikov VV
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Lmx1a regulates fates and location of cells originating from the cerebellar rhombic lip and telencephalic cortical hem.
Volume: 107
Issue: 23
Pages: 10725-30
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Publication
21440093 | J:171625
First Author: Griesel G
Year: 2011
Journal: Gene Expr Patterns
Title: Generation of knockout mice expressing a GFP-reporter under the control of the Lmx1a locus.
Volume: 11
Issue: 5-6
Pages: 345-8
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Publication
12351192 | J:79521
First Author: Failli V
Year: 2002
Journal: Mech Dev
Title: Expression of the LIM-homeodomain gene Lmx1a (dreher) during development of the mouse nervous system.
Volume: 118
Issue: 1-2
Pages: 225-8
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Publication
15148302 | J:91822
First Author: Chizhikov VV
Year: 2004
Journal: Development
Title: Control of roof plate formation by Lmx1a in the developing spinal cord.
Volume: 131
Issue: 11
Pages: 2693-705
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Publication
17019651 | J:115043
First Author: Chizhikov V
Year: 2006
Journal: Mamm Genome
Title: Molecular definition of an allelic series of mutations disrupting the mouse Lmx1a (dreher) gene.
Volume: 17
Issue: 10
Pages: 1025-32
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Publication
- | J:74414
     
First Author: Washburn L
Year: 2002
Journal: MGI Direct Data Submission
Title: New allele of Lmx1a
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Publication
19383789 | J:148323
First Author: Friling S
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Efficient production of mesencephalic dopamine neurons by Lmx1a expression in embryonic stem cells.
Volume: 106
Issue: 18
Pages: 7613-8
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Publication
19540218 | J:152264
First Author: Koo SK
Year: 2009
Journal: Dev Biol
Title: Lmx1a maintains proper neurogenic, sensory, and non-sensory domains in the mammalian inner ear.
Volume: 333
Issue: 1
Pages: 14-25
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Publication
27287799 | J:235741
First Author: Gross S
Year: 2016
Journal: Development
Title: The novel enterochromaffin marker Lmx1a regulates serotonin biosynthesis in enteroendocrine cell lineages downstream of Nkx2.2.
Volume: 143
Issue: 14
Pages: 2616-28
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Publication
25747864 | J:221128
 
First Author: Yuan J
Year: 2015
Journal: Brain Res
Title: Interaction between Oc-1 and Lmx1a promotes ventral midbrain dopamine neural stem cells differentiation into dopamine neurons.
Volume: 1608
Pages: 40-50
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Publication
10693804 | J:60593
First Author: Millonig JH
Year: 2000
Journal: Nature
Title: The mouse Dreher gene Lmx1a controls formation of the roof plate in the vertebrate CNS.
Volume: 403
Issue: 6771
Pages: 764-9
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Publication
22564125 | J:186499
First Author: Chung S
Year: 2012
Journal: J Neurochem
Title: Lmx1a regulates dopamine transporter gene expression during ES cell differentiation and mouse embryonic development.
Volume: 122
Issue: 2
Pages: 244-50
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Publication
27407143 | J:235155
First Author: Doucet-Beaupré H
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Lmx1a and Lmx1b regulate mitochondrial functions and survival of adult midbrain dopaminergic neurons.
Volume: 113
Issue: 30
Pages: E4387-96
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Publication
24194952 | J:209191
First Author: Hunt CP
Year: 2013
Journal: PLoS One
Title: DNA-dependent protein kinase is a context dependent regulator of Lmx1a and midbrain specification.
Volume: 8
Issue: 10
Pages: e78759
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Publication
30770393 | J:272552
 
First Author: Fregoso SP
Year: 2019
Journal: Development
Title: Lmx1a drives Cux2 expression in the cortical hem through activation of a conserved intronic enhancer.
Volume: 146
Issue: 5
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Publication
21880902 | J:176226
First Author: Yan CH
Year: 2011
Journal: J Neurosci
Title: Lmx1a and lmx1b function cooperatively to regulate proliferation, specification, and differentiation of midbrain dopaminergic progenitors.
Volume: 31
Issue: 35
Pages: 12413-25
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Publication
29769265 | J:262601
First Author: Huang Y
Year: 2018
Journal: J Neurosci
Title: Reciprocal Negative Regulation Between Lmx1a and Lmo4 Is Required for Inner Ear Formation.
Volume: 38
Issue: 23
Pages: 5429-5440
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Publication
26526610 | J:228082
First Author: Doucet-Beaupré H
Year: 2015
Journal: FEBS Lett
Title: Cell fate determination, neuronal maintenance and disease state: The emerging role of transcription factors Lmx1a and Lmx1b.
Volume: 589
Issue: 24 Pt A
Pages: 3727-38
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GXD Expression
GXD Expression
   
Probe: MGI:6176524
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190726
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Lmx1a
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:6176524
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190726
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Lmx1a
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:6176524
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190726
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Lmx1a
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:6176524
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190726
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Lmx1a
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6176524
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190726
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Lmx1a
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6176524
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190726
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Lmx1a
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6176524
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190726
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Lmx1a
Detected: true
Specimen Num: 7
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Publication
- | J:128476
     
First Author: Ward-Bailey P
Year: 2008
Journal: MGI Direct Data Submission
Title: Two new spontaneous mutations in the Lmx1a gene, dreher 10 Jackson and dreher 11 Jackson
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Publication
31932950 | J:313342
First Author: Nichols DH
Year: 2020
Journal: Cell Tissue Res
Title: Interaction with ectopic cochlear crista sensory epithelium disrupts basal cochlear sensory epithelium development in Lmx1a mutant mice.
Volume: 380
Issue: 3
Pages: 435-448
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Publication
33246067 | J:301713
 
First Author: Chizhikov VV
Year: 2021
Journal: Neuroscience
Title: Lmx1a and Lmx1b are Redundantly Required for the Development of Multiple Components of the Mammalian Auditory System.
Volume: 452
Pages: 247-264
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Publication
24066094 | J:206496
First Author: Hoekstra EJ
Year: 2013
Journal: PLoS One
Title: Lmx1a encodes a rostral set of mesodiencephalic dopaminergic neurons marked by the Wnt/B-catenin signaling activator R-spondin 2.
Volume: 8
Issue: 9
Pages: e74049
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Publication
23226461 | J:194385
First Author: Steffes G
Year: 2012
Journal: PLoS One
Title: Mutanlallemand (mtl) and Belly Spot and Deafness (bsd) are two new mutations of Lmx1a causing severe cochlear and vestibular defects.
Volume: 7
Issue: 11
Pages: e51065
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Publication
29038581 | J:254718
First Author: Chabrat A
Year: 2017
Journal: Nat Commun
Title: Transcriptional repression of Plxnc1 by Lmx1a and Lmx1b directs topographic dopaminergic circuit formation.
Volume: 8
Issue: 1
Pages: 933
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Publication
23106268 | J:209053
First Author: Hoekstra EJ
Year: 2013
Journal: Eur J Neurosci
Title: Lmx1a is an activator of Rgs4 and Grb10 and is responsible for the correct specification of rostral and medial mdDA neurons.
Volume: 37
Issue: 1
Pages: 23-32
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Publication
19607821 | J:152413
First Author: Lin W
Year: 2009
Journal: Dev Biol
Title: Foxa1 and Foxa2 function both upstream of and cooperatively with Lmx1a and Lmx1b in a feedforward loop promoting mesodiencephalic dopaminergic neuron development.
Volume: 333
Issue: 2
Pages: 386-96
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Publication
20035737 | J:157957
First Author: Nakatani T
Year: 2010
Journal: Dev Biol
Title: Lmx1a and Lmx1b cooperate with Foxa2 to coordinate the specification of dopaminergic neurons and control of floor plate cell differentiation in the developing mesencephalon.
Volume: 339
Issue: 1
Pages: 101-13
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GXD Expression
GXD Expression
Probe: MGI:7338955
Assay Type: RNA in situ
Annotation Date: 2022-09-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:7339057
Age: embryonic day 11.5
Image: 7M
Note: Complementary expression of Lmx1a and Dll1 was seen.
Specimen Label: 7M
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6416278
Age: embryonic day 15.5
Image: 2D
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 2D
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6416278
Age: embryonic day 16.5
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: not shown E16.5 Nf2;Emx1-Cre (2H)
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6416278
Age: embryonic day 15.5
Image: S2D'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: S2D'
Detected: true
Specimen Num: 36
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6416278
Age: embryonic day 16.5
Image: S3F'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: S3F'
Detected: true
Specimen Num: 44
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691326
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6416278
Age: embryonic day 18.5
Image: 3F'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 3F'
Detected: true
Specimen Num: 18
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6416278
Age: embryonic day 15.5
Image: 3K'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 3K'
Detected: true
Specimen Num: 23
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6416278
Age: embryonic day 15.5
Image: 8A
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 8A
Detected: true
Specimen Num: 31
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6416278
Age: embryonic day 14.5
Image: S2B'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: S2B'
Detected: true
Specimen Num: 34
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GXD Expression
GXD Expression
 
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6416278
Age: embryonic day 14.5
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: not shown E14.5 Nf2;Emx1-Cre (2E)
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6416278
Age: embryonic day 16.5
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: not shown E16.5 Nf2;Emx1-Cre (2E)
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6416278
Age: embryonic day 15.5
Image: 2G
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 2G
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6416278
Age: embryonic day 14.5
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: not shown E14.5 Nf2;Emx1-Cre (2H)
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6416278
Age: embryonic day 16.5
Image: S2F'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: S2F'
Detected: true
Specimen Num: 38
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6416278
Age: embryonic day 14.5
Image: S3B'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: S3B'
Detected: true
Specimen Num: 40
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6416278
Age: embryonic day 14.5
Image: S3D'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: S3D'
Detected: true
Specimen Num: 42
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6416278
Age: embryonic day 16.5
Image: S3H'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: S3H'
Detected: true
Specimen Num: 46
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6416278
Age: embryonic day 14.5
Image: 3D'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 3D'
Detected: true
Specimen Num: 16
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6416278
Age: embryonic day 16.5
Image: 3E'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 3E'
Detected: true
Specimen Num: 17
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6416278
Age: embryonic day 14.5
Image: 3J'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 3J'
Detected: true
Specimen Num: 22
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GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691324
Pattern: Regionally restricted
Stage: TS24
Assay Id: MGI:6416278
Age: embryonic day 16.5
Image: 3L'
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 3L'
Detected: true
Specimen Num: 24
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6416278
Age: embryonic day 14.5
Image: 4J
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 4J
Detected: true
Specimen Num: 26
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691322
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:6416278
Age: embryonic day 14.5
Image: 5B
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 5B
Detected: true
Specimen Num: 28
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:6407030
Assay Type: Immunohistochemistry
Annotation Date: 2020-05-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691325
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:6416278
Age: embryonic day 17.5
Image: 5J
Note: The cortical hem was enlarged in the conditional mutant, and the number of Lmx1a immunolabeled cells was increased.
Specimen Label: 5J
Detected: true
Specimen Num: 30
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7431210
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7431456
Age: embryonic day 12.5
Image: S7O
Note: Virtually all Lmx1a+ cells were GFP+ in dreher mice. No ectopic expression of Lmx1a was detected in the mutant telencephalon.
Specimen Label: S7O
Detected: true
Specimen Num: 33
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7431210
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3814220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7431456
Age: embryonic day 12.5
Image: S7O
Note: Virtually all Lmx1a+ cells were GFP+ in dreher mice. No ectopic expression of Lmx1a was detected in the mutant telencephalon.
Specimen Label: S7O
Detected: true
Specimen Num: 33
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:7431210
Assay Type: Immunohistochemistry
Annotation Date: 2023-02-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3814217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7431456
Age: embryonic day 10.5
Image: S8D
Note: The lateral limit of the expression domain in the cortical hem was indicated. In the mutant, the Lhx2 expression domain extended medially and included almost the entire cortical hem with significant overlap with the Lmx1a expression domain.
Specimen Label: S8D
Detected: true
Specimen Num: 35
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•
•
•
•
Publication
23160833 | J:319000
First Author: Sillitoe RV
Year: 2014
Journal: Brain Struct Funct
Title: Purkinje cell compartmentalization in the cerebellum of the spontaneous mutant mouse dreher.
Volume: 219
Issue: 1
Pages: 35-47
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•
Publication
34816488 | J:324869
First Author: Suto JI
Year: 2022
Journal: Congenit Anom (Kyoto)
Title: Identification of a novel mutant allele of LIM homeobox transcription factor 1 alpha (dreher) in mice.
Volume: 62
Issue: 1
Pages: 18-26
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•
•
•
•
Publication
29199954 | J:254987
   
First Author: Mann ZF
Year: 2017
Journal: Elife
Title: Shaping of inner ear sensory organs through antagonistic interactions between Notch signalling and Lmx1a.
Volume: 6
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•
•
•
Publication
32075770 | J:287685
First Author: Salesse C
Year: 2020
Journal: Cell Rep
Title: Opposite Control of Excitatory and Inhibitory Synapse Formation by Slitrk2 and Slitrk5 on Dopamine Neurons Modulates Hyperactivity Behavior.
Volume: 30
Issue: 7
Pages: 2374-2386.e5
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•
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Publication
18942141 | J:140711
First Author: Huang M
Year: 2008
Journal: Dev Dyn
Title: Diverse expression patterns of LIM-homeodomain transcription factors (LIM-HDs) in mammalian inner ear development.
Volume: 237
Issue: 11
Pages: 3305-12
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•
•
•
Publication
19951692 | J:228113
First Author: Chung S
Year: 2009
Journal: Cell Stem Cell
Title: Wnt1-lmx1a forms a novel autoregulatory loop and controls midbrain dopaminergic differentiation synergistically with the SHH-FoxA2 pathway.
Volume: 5
Issue: 6
Pages: 646-58
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•
•
•
Publication
27246266 | J:253782
 
First Author: Hedlund E
Year: 2016
Journal: Sci Rep
Title: Dopamine Receptor Antagonists Enhance Proliferation and Neurogenesis of Midbrain Lmx1a-expressing Progenitors.
Volume: 6
Pages: 26448
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•
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•
Publication
16364898 | J:107595
First Author: Landsberg RL
Year: 2005
Journal: Neuron
Title: Hindbrain rhombic lip is comprised of discrete progenitor cell populations allocated by Pax6.
Volume: 48
Issue: 6
Pages: 933-47
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•
•
Publication
31729356 | J:281616
First Author: Chizhikov VV
Year: 2019
Journal: Nat Commun
Title: Early dorsomedial tissue interactions regulate gyrification of distal neocortex.
Volume: 10
Issue: 1
Pages: 5192
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Publication
19825428 | J:154096
First Author: Nelander J
Year: 2009
Journal: Gene Expr Patterns
Title: Organization of the human embryonic ventral mesencephalon.
Volume: 9
Issue: 8
Pages: 555-61
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•
•
•
•
Publication
25915474 | J:222854
First Author: Laguna A
Year: 2015
Journal: Nat Neurosci
Title: Dopaminergic control of autophagic-lysosomal function implicates Lmx1b in Parkinson's disease.
Volume: 18
Issue: 6
Pages: 826-35
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•
Publication
35110543 | J:320719
First Author: Parichha A
Year: 2022
Journal: Nat Commun
Title: Constitutive activation of canonical Wnt signaling disrupts choroid plexus epithelial fate.
Volume: 13
Issue: 1
Pages: 633
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•
•
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•
Publication
28733161 | J:249803
First Author: Guerrero-Flores G
Year: 2017
Journal: Dev Biol
Title: Functional determination of the differentiation potential of ventral mesencephalic neural precursor cells during dopaminergic neurogenesis.
Volume: 429
Issue: 1
Pages: 56-70
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Publication
29163030 | J:310537
 
First Author: Mesman S
Year: 2017
Journal: Front Mol Neurosci
Title: Tcf12 Is Involved in Early Cell-Fate Determination and Subset Specification of Midbrain Dopamine Neurons.
Volume: 10
Pages: 353
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•
•
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•
Publication
12358782 | J:78622
First Author: Krüger M
Year: 2002
Journal: J Neurochem
Title: The homeobox containing gene Lbx1 is required for correct dorsal-ventral patterning of the neural tube.
Volume: 82
Issue: 4
Pages: 774-82
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Publication
23444360 | J:194842
First Author: Yang J
Year: 2013
Journal: Development
Title: Dynamic temporal requirement of Wnt1 in midbrain dopamine neuron development.
Volume: 140
Issue: 6
Pages: 1342-52
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•
Publication
16790481 | J:119033
First Author: Chizhikov VV
Year: 2006
Journal: Development
Title: The roof plate regulates cerebellar cell-type specification and proliferation.
Volume: 133
Issue: 15
Pages: 2793-804
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Publication
23324743 | J:193686
First Author: Andersson ER
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Wnt5a cooperates with canonical Wnts to generate midbrain dopaminergic neurons in vivo and in stem cells.
Volume: 110
Issue: 7
Pages: E602-10
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Publication
18820178 | J:143341
First Author: Omodei D
Year: 2008
Journal: Development
Title: Anterior-posterior graded response to Otx2 controls proliferation and differentiation of dopaminergic progenitors in the ventral mesencephalon.
Volume: 135
Issue: 20
Pages: 3459-70
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Publication
22537018 | J:186263
First Author: Ratzka A
Year: 2012
Journal: J Neurochem
Title: Fibroblast growth factor 2 regulates dopaminergic neuron development in vivo.
Volume: 122
Issue: 1
Pages: 94-105
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Publication
21752929 | J:175535
First Author: Deng Q
Year: 2011
Journal: Development
Title: Specific and integrated roles of Lmx1a, Lmx1b and Phox2a in ventral midbrain development.
Volume: 138
Issue: 16
Pages: 3399-408
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Publication
17670789 | J:124270
First Author: Ono Y
Year: 2007
Journal: Development
Title: Differences in neurogenic potential in floor plate cells along an anteroposterior location: midbrain dopaminergic neurons originate from mesencephalic floor plate cells.
Volume: 134
Issue: 17
Pages: 3213-25
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Publication
15183721 | J:92188
First Author: Millen KJ
Year: 2004
Journal: Dev Biol
Title: Roof plate and dorsal spinal cord dl1 interneuron development in the dreher mutant mouse.
Volume: 270
Issue: 2
Pages: 382-92
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Publication
26424886 | J:226472
First Author: Fukusumi Y
Year: 2015
Journal: J Neurosci
Title: Dickkopf 3 Promotes the Differentiation of a Rostrolateral Midbrain Dopaminergic Neuronal Subset In Vivo and from Pluripotent Stem Cells In Vitro in the Mouse.
Volume: 35
Issue: 39
Pages: 13385-401
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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