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Search results 1 to 100 out of 401 for Trp53bp1

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Protein Coding Gene
MGI:1351320 | Trp53bp1
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
 
Probe: MGI:5693621
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6316062
Age: postnatal adult
Note: Atm-/- mice harbored elevated numbers of Trp53bp1 foci in hippocampus and lung compared to wild type.
Specimen Label: adult Atm-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5693621
Assay Type: Immunohistochemistry
Annotation Date: 2019-07-05
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6316062
Age: postnatal adult
Note: Atm-/- mice harbored elevated numbers of Trp53bp1 foci in hippocampus and lung compared to wild type.
Specimen Label: adult Atm-/-
Detected: true
Specimen Num: 2
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Publication
23657012 | J:197442
First Author: Bowman-Colin C
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Palb2 synergizes with Trp53 to suppress mammary tumor formation in a model of inherited breast cancer.
Volume: 110
Issue: 21
Pages: 8632-7
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Protein Coding Gene
MGP_CAROLIEiJ_G0024186 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026385 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026346 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026325 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026359 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026105 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1351320 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026806 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025567 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026081 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026220 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026321 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026201 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026861 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025303 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025636 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025628 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025102 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11934988 | J:76360
First Author: Celeste A
Year: 2002
Journal: Science
Title: Genomic instability in mice lacking histone H2AX.
Volume: 296
Issue: 5569
Pages: 922-7
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Publication
23241889 | J:191725
First Author: Pei H
Year: 2013
Journal: J Immunol
Title: The histone methyltransferase MMSET regulates class switch recombination.
Volume: 190
Issue: 2
Pages: 756-63
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Publication
19414588 | J:151185
First Author: Wu J
Year: 2009
Journal: J Biol Chem
Title: PTIP regulates 53BP1 and SMC1 at the DNA damage sites.
Volume: 284
Issue: 27
Pages: 18078-84
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
26774285 | J:231089
First Author: Tkáč J
Year: 2016
Journal: Mol Cell
Title: HELB Is a Feedback Inhibitor of DNA End Resection.
Volume: 61
Issue: 3
Pages: 405-418
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Publication
30297459 | J:293083
 
First Author: Li ML
Year: 2019
Journal: Mol Cell Biol
Title: Phosphorylation of TIP60 Suppresses 53BP1 Localization at DNA Damage Sites.
Volume: 39
Issue: 1
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Publication
23333305 | J:195061
First Author: Chapman JR
Year: 2013
Journal: Mol Cell
Title: RIF1 is essential for 53BP1-dependent nonhomologous end joining and suppression of DNA double-strand break resection.
Volume: 49
Issue: 5
Pages: 858-71
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Publication
23333306 | J:197099
First Author: Escribano-Díaz C
Year: 2013
Journal: Mol Cell
Title: A cell cycle-dependent regulatory circuit composed of 53BP1-RIF1 and BRCA1-CtIP controls DNA repair pathway choice.
Volume: 49
Issue: 5
Pages: 872-83
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Publication
23306437 | J:193247
First Author: Zimmermann M
Year: 2013
Journal: Science
Title: 53BP1 regulates DSB repair using Rif1 to control 5' end resection.
Volume: 339
Issue: 6120
Pages: 700-4
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Publication
23306439 | J:193246
First Author: Di Virgilio M
Year: 2013
Journal: Science
Title: Rif1 prevents resection of DNA breaks and promotes immunoglobulin class switching.
Volume: 339
Issue: 6120
Pages: 711-5
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Publication
8910340 | J:36914
First Author: Datta B
Year: 1996
Journal: J Biol Chem
Title: p202, an interferon-inducible modulator of transcription, inhibits transcriptional activation by the p53 tumor suppressor protein, and a segment from the p53-binding protein 1 that binds to p202 overcomes this inhibition.
Volume: 271
Issue: 44
Pages: 27544-55
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Publication
15542852 | J:94306
First Author: Akhter S
Year: 2004
Journal: Mol Cell Biol
Title: Deficiency in SNM1 abolishes an early mitotic checkpoint induced by spindle stress.
Volume: 24
Issue: 23
Pages: 10448-55
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Publication
20080757 | J:156522
First Author: Ramachandran S
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: The RNF8/RNF168 ubiquitin ligase cascade facilitates class switch recombination.
Volume: 107
Issue: 2
Pages: 809-14
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Publication
28051062 | J:238544
 
First Author: Liu X
Year: 2017
Journal: Nat Commun
Title: PAXX promotes KU accumulation at DNA breaks and is essential for end-joining in XLF-deficient mice.
Volume: 8
Pages: 13816
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Publication
23714778 | J:197673
First Author: Saxe JP
Year: 2013
Journal: EMBO J
Title: Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline.
Volume: 32
Issue: 13
Pages: 1869-85
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Publication
11801725 | J:74292
First Author: Jullien D
Year: 2002
Journal: J Cell Sci
Title: Kinetochore localisation of the DNA damage response component 53BP1 during mitosis.
Volume: 115
Issue: Pt 1
Pages: 71-9
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Publication
12640136 | J:82512
First Author: Ward IM
Year: 2003
Journal: Mol Cell Biol
Title: p53 Binding protein 53BP1 is required for DNA damage responses and tumor suppression in mice.
Volume: 23
Issue: 7
Pages: 2556-63
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Publication
15159415 | J:91130
First Author: Ward IM
Year: 2004
Journal: J Cell Biol
Title: 53BP1 is required for class switch recombination.
Volume: 165
Issue: 4
Pages: 459-64
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Publication
15077110 | J:89802
First Author: Manis JP
Year: 2004
Journal: Nat Immunol
Title: 53BP1 links DNA damage-response pathways to immunoglobulin heavy chain class-switch recombination.
Volume: 5
Issue: 5
Pages: 481-7
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Publication
20362325 | J:240590
First Author: Bunting SF
Year: 2010
Journal: Cell
Title: 53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks.
Volume: 141
Issue: 2
Pages: 243-54
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Publication
23209566 | J:240587
First Author: Hartlerode AJ
Year: 2012
Journal: PLoS One
Title: Impact of histone H4 lysine 20 methylation on 53BP1 responses to chromosomal double strand breaks.
Volume: 7
Issue: 11
Pages: e49211
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Publication
26308889 | J:262446
First Author: Dong J
Year: 2015
Journal: Nature
Title: Orientation-specific joining of AID-initiated DNA breaks promotes antibody class switching.
Volume: 525
Issue: 7567
Pages: 134-139
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Publication
20059953 | J:156017
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
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Publication
26123487 | J:224588
First Author: Kato Y
Year: 2015
Journal: Hum Mol Genet
Title: FANCB is essential in the male germline and regulates H3K9 methylation on the sex chromosomes during meiosis.
Volume: 24
Issue: 18
Pages: 5234-49
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Publication
17500065 | J:123598
First Author: Cho YW
Year: 2007
Journal: J Biol Chem
Title: PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.
Volume: 282
Issue: 28
Pages: 20395-406
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Publication
30022168 | J:265301
First Author: Noordermeer SM
Year: 2018
Journal: Nature
Title: The shieldin complex mediates 53BP1-dependent DNA repair.
Volume: 560
Issue: 7716
Pages: 117-121
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Publication
18676810 | J:139510
First Author: Schotta G
Year: 2008
Journal: Genes Dev
Title: A chromatin-wide transition to H4K20 monomethylation impairs genome integrity and programmed DNA rearrangements in the mouse.
Volume: 22
Issue: 15
Pages: 2048-61
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:94338
     
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
19948482 | J:155449
First Author: Buonomo SB
Year: 2009
Journal: J Cell Biol
Title: Mammalian Rif1 contributes to replication stress survival and homology-directed repair.
Volume: 187
Issue: 3
Pages: 385-98
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Publication
19716796 | J:154193
First Author: Cao L
Year: 2009
Journal: Mol Cell
Title: A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.
Volume: 35
Issue: 4
Pages: 534-41
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Publication
29311308 | J:260725
First Author: Panchakshari RA
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: DNA double-strand break response factors influence end-joining features of IgH class switch and general translocation junctions.
Volume: 115
Issue: 4
Pages: 762-767
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Publication
27320916 | J:238371
First Author: Rocha PP
Year: 2016
Journal: Cell Rep
Title: A Damage-Independent Role for 53BP1 that Impacts Break Order and Igh Architecture during Class Switch Recombination.
Volume: 16
Issue: 1
Pages: 48-55
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Publication
23727112 | J:198413
First Author: Callen E
Year: 2013
Journal: Cell
Title: 53BP1 mediates productive and mutagenic DNA repair through distinct phosphoprotein interactions.
Volume: 153
Issue: 6
Pages: 1266-80
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Publication
33200984 | J:299451
   
First Author: Atkins A
Year: 2020
Journal: Elife
Title: SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis.
Volume: 9
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Publication
- | J:82961
     
First Author: JAX National Heart, Lung and Blood Program for Genomic Applications (PGA)
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the JAX NHLBI ENU Mutagenesis Program
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Publication
29078319 | J:271417
First Author: Su D
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: PTIP chromatin regulator controls development and activation of B cell subsets to license humoral immunity in mice.
Volume: 114
Issue: 44
Pages: E9328-E9337
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Publication
19001091 | J:144766
First Author: Adelman CA
Year: 2009
Journal: Mol Cell Biol
Title: Rad50 is dispensable for the maintenance and viability of postmitotic tissues.
Volume: 29
Issue: 2
Pages: 483-92
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Publication
32737294 | J:331939
First Author: Keil JM
Year: 2020
Journal: Nat Commun
Title: Symmetric neural progenitor divisions require chromatin-mediated homologous recombination DNA repair by Ino80.
Volume: 11
Issue: 1
Pages: 3839
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Publication
25605905 | J:217665
First Author: Wang T
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Real-time resolution of point mutations that cause phenovariance in mice.
Volume: 112
Issue: 5
Pages: E440-9
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Publication
23271346 | J:192592
First Author: Sotiropoulou PA
Year: 2013
Journal: Genes Dev
Title: BRCA1 deficiency in skin epidermis leads to selective loss of hair follicle stem cells and their progeny.
Volume: 27
Issue: 1
Pages: 39-51
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Publication
28137874 | J:240936
First Author: Choi JH
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: IgD class switching is initiated by microbiota and limited to mucosa-associated lymphoid tissue in mice.
Volume: 114
Issue: 7
Pages: E1196-E1204
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Publication
35969748 | J:327430
First Author: Yang Y
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Transcription-replication conflicts in primordial germ cells necessitate the Fanconi anemia pathway to safeguard genome stability.
Volume: 119
Issue: 34
Pages: e2203208119
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Publication
30704900 | J:274082
First Author: Zong D
Year: 2019
Journal: Mol Cell
Title: BRCA1 Haploinsufficiency Is Masked by RNF168-Mediated Chromatin Ubiquitylation.
Volume: 73
Issue: 6
Pages: 1267-1281.e7
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Publication
32051414 | J:286736
First Author: Paiano J
Year: 2020
Journal: Nat Commun
Title: ATM and PRDM9 regulate SPO11-bound recombination intermediates during meiosis.
Volume: 11
Issue: 1
Pages: 857
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Publication
16400328 | J:106450
First Author: Ramiro AR
Year: 2006
Journal: Nature
Title: Role of genomic instability and p53 in AID-induced c-myc-Igh translocations.
Volume: 440
Issue: 7080
Pages: 105-9
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Publication
25264618 | J:222492
First Author: Rybanska-Spaeder I
Year: 2014
Journal: PLoS One
Title: 53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.
Volume: 9
Issue: 9
Pages: e108731
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Publication
20231360 | J:162591
First Author: Orsburn B
Year: 2010
Journal: Mol Cell Biol
Title: Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
Volume: 30
Issue: 10
Pages: 2341-52
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Publication
23858098 | J:205436
First Author: Rybanska-Spaeder I
Year: 2013
Journal: Mol Cancer Res
Title: 53BP1 is limiting for NHEJ repair in ATM-deficient model systems that are subjected to oncogenic stress or radiation.
Volume: 11
Issue: 10
Pages: 1223-34
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Publication
23254285 | J:194603
First Author: Bothmer A
Year: 2013
Journal: J Exp Med
Title: Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.
Volume: 210
Issue: 1
Pages: 115-23
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Publication
24842372 | J:213733
First Author: Polato F
Year: 2014
Journal: J Exp Med
Title: CtIP-mediated resection is essential for viability and can operate independently of BRCA1.
Volume: 211
Issue: 6
Pages: 1027-36
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Publication
22556254 | J:184522
First Author: Sfeir A
Year: 2012
Journal: Science
Title: Removal of shelterin reveals the telomere end-protection problem.
Volume: 336
Issue: 6081
Pages: 593-7
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Publication
24725274 | J:210514
First Author: Martínez P
Year: 2014
Journal: Aging Cell
Title: Essential role for the TRF2 telomere protein in adult skin homeostasis.
Volume: 13
Issue: 4
Pages: 656-68
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18931659 | J:143563
First Author: Dimitrova N
Year: 2008
Journal: Nature
Title: 53BP1 promotes non-homologous end joining of telomeres by increasing chromatin mobility.
Volume: 456
Issue: 7221
Pages: 524-8
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Publication
23345425 | J:194338
First Author: Lottersberger F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Role of 53BP1 oligomerization in regulating double-strand break repair.
Volume: 110
Issue: 6
Pages: 2146-51
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Publication
26303202 | J:233378
First Author: Barazzuol L
Year: 2015
Journal: J Cell Sci
Title: Low levels of endogenous or X-ray-induced DNA double-strand breaks activate apoptosis in adult neural stem cells.
Volume: 128
Issue: 19
Pages: 3597-606
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Publication
19450527 | J:150435
First Author: Callén E
Year: 2009
Journal: Mol Cell
Title: Essential role for DNA-PKcs in DNA double-strand break repair and apoptosis in ATM-deficient lymphocytes.
Volume: 34
Issue: 3
Pages: 285-97
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Publication
17599403 | J:143821
First Author: Callén E
Year: 2007
Journal: Cell
Title: ATM prevents the persistence and propagation of chromosome breaks in lymphocytes.
Volume: 130
Issue: 1
Pages: 63-75
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Publication
21734301 | J:174554
First Author: Gatz SA
Year: 2011
Journal: J Neurosci
Title: Requirement for DNA ligase IV during embryonic neuronal development.
Volume: 31
Issue: 27
Pages: 10088-100
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Publication
35764636 | J:332737
First Author: Vincendeau E
Year: 2022
Journal: Nat Commun
Title: SHLD1 is dispensable for 53BP1-dependent V(D)J recombination but critical for productive class switch recombination.
Volume: 13
Issue: 1
Pages: 3707
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Publication
35623353 | J:326251
First Author: Kalogeropoulou A
Year: 2022
Journal: Stem Cell Reports
Title: Intrinsic neural stem cell properties define brain hypersensitivity to genotoxic stress.
Volume: 17
Issue: 6
Pages: 1395-1410
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Publication
26745185 | J:229930
 
First Author: Nechiporuk T
Year: 2016
Journal: Elife
Title: The REST remodeling complex protects genomic integrity during embryonic neurogenesis.
Volume: 5
Pages: e09584
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Publication
19633665 | J:152528
First Author: Lee Y
Year: 2009
Journal: Nat Neurosci
Title: The genesis of cerebellar interneurons and the prevention of neural DNA damage require XRCC1.
Volume: 12
Issue: 8
Pages: 973-80
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Publication
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Title: 53BP1 Contributes to Igh Locus Chromatin Topology during Class Switch Recombination.
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Title: Identification of early replicating fragile sites that contribute to genome instability.
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Title: 53BP1 regulates DNA resection and the choice between classical and alternative end joining during class switch recombination.
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Title: 53BP1 alters the landscape of DNA rearrangements and suppresses AID-induced B cell lymphoma.
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