|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 301 to 316 out of 316 for Prdm12

<< First    < Previous  |  Next >    Last >>
0.22s
Type Details Score
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication
First Author: Nagy V
Year: 2015
Journal: Cell Cycle
Title: The evolutionarily conserved transcription factor PRDM12 controls sensory neuron development and pain perception.
Volume: 14
Issue: 12
Pages: 1799-808
Protein
Organism: Mus musculus/domesticus
Length: 365  
Fragment?: false
DO Term
HT Experiment  
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
Protein Domain
Type: Domain
Description: This entry represents the PR/SET domain found in PR domain zinc finger protein 12 (PRDM12). PRDM12 is essential for human pain perception []. It is also a key regulator of sensory neuronal specification in Xenopus []. It has been shown to initiate and maintain the expression of TrkA in developing nociceptors [].The PRDM family members are characterised by the presence of a N-terminal PR (PRDI-BF1 and RIZ1 homology) domain followed by multiple zinc fingers which confer DNA binding activity. PR domains are only distantly related to the classical SET methyltransferase domains []. They are involved in epigenetic regulation of gene expression through their intrinsic histone methyltransferase activity or via interactions with other chromatin modifying enzymes [].
Publication    
First Author: Yu H
Year: 2022
Journal: Elife
Title: Developmental single-cell transcriptomics of hypothalamic POMC neurons reveal the genetic trajectories of multiple neuropeptidergic phenotypes.
Volume: 11
Publication
First Author: Wu H
Year: 2013
Journal: Cell Rep
Title: Molecular basis for the regulation of the H3K4 methyltransferase activity of PRDM9.
Volume: 5
Issue: 1
Pages: 13-20
Publication  
First Author: Casamassimi A
Year: 2020
Journal: Int J Mol Sci
Title: Multifaceted Role of PRDM Proteins in Human Cancer.
Volume: 21
Issue: 7