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Search results 201 to 279 out of 279 for Mboat7

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Type Details Score
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1757728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692192
Age: postnatal adult
Image: MRC Harwell_901331
Specimen Label: MRC Harwell_901331
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5310350
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757522
Stage: TS22
Assay Id: MGI:5423674
Age: embryonic day 14.5
Specimen Label: EH1582; Specimen C2688
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3281228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692192
Age: postnatal adult
Image: MRC Harwell_901355
Specimen Label: MRC Harwell_901355
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:5310350
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1738322
Stage: TS22
Assay Id: MGI:5423674
Age: embryonic day 14.5
Specimen Label: EH1582; Specimen C2688
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:5310350
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1802422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423674
Age: embryonic day 14.5
Image: EH1582; Specimen C2688
Specimen Label: EH1582; Specimen C2688
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692192
Age: postnatal adult
Image: MRC Harwell_901343
Specimen Label: MRC Harwell_901343
Detected: true
Specimen Num: 14
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692192
Age: postnatal adult
Image: MRC Harwell_901349
Specimen Label: MRC Harwell_901349
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692192
Age: postnatal adult
Image: MRC Harwell_901353
Specimen Label: MRC Harwell_901353
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:6477313
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3521726
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6477320
Age: embryonic day 18.5
Image: 1G +/+
Specimen Label: 1G +/+
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:5310350
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1768022
Stage: TS22
Assay Id: MGI:5423674
Age: embryonic day 14.5
Note: Expression was not detected in the skull (base and vault).
Specimen Label: EH1582; Specimen C2688
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:5310350
Assay Type: RNA in situ
Annotation Date: 2012-06-12
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:2672022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:5423674
Age: embryonic day 14.5
Image: EH1582; Specimen C2688
Note: Expression was weak in whisker follicle.
Specimen Label: EH1582; Specimen C2688
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6477313
Assay Type: Immunohistochemistry
Annotation Date: 2020-12-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3561126
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6477320
Age: embryonic day 18.5
Image: 1F +/+
Specimen Label: 1F +/+
Detected: true
Specimen Num: 5
Publication
First Author: Tabe S
Year: 2016
Journal: FASEB J
Title: Lysophosphatidylethanolamine acyltransferase 1/membrane-bound O-acyltransferase 1 regulates morphology and function of P19C6 cell-derived neurons.
Volume: 30
Issue: 7
Pages: 2591-601
Publication
First Author: Wang Z
Year: 2023
Journal: Cell
Title: Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease.
Volume: 186
Issue: 9
Pages: 1968-1984.e20
Publication
First Author: Sato T
Year: 2023
Journal: J Biol Chem
Title: LPGAT1/LPLAT7 regulates acyl chain profiles at the sn-1 position of phospholipids in murine skeletal muscles.
Volume: 299
Issue: 7
Pages: 104848
Publication
First Author: Saliakoura M
Year: 2020
Journal: Oncogene
Title: The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer.
Volume: 39
Issue: 14
Pages: 2948-2960
Publication
First Author: Lee HC
Year: 2012
Journal: Mol Biol Cell
Title: LPIAT1 regulates arachidonic acid content in phosphatidylinositol and is required for cortical lamination in mice.
Volume: 23
Issue: 24
Pages: 4689-700
Publication
First Author: Daigo Y
Year: 2004
Journal: J Gastroenterol
Title: Isolation of novel mouse genes that were differentially expressed in W/W(V) mouse fundus.
Volume: 39
Issue: 3
Pages: 238-41
Publication
First Author: Vogel P
Year: 2012
Journal: Vet Pathol
Title: Congenital hydrocephalus in genetically engineered mice.
Volume: 49
Issue: 1
Pages: 166-81
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
DO Term
Protein
Organism: Mus musculus/domesticus
Length: 519  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 492  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 461  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 435  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 211  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 404  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 111  
Fragment?: true
Publication
First Author: Orland MD
Year: 2005
Journal: Biochim Biophys Acta
Title: Acyl coenzyme A dependent retinol esterification by acyl coenzyme A: diacylglycerol acyltransferase 1.
Volume: 1737
Issue: 1
Pages: 76-82
Protein Domain
Type: Family
Description: The MBOAT (membrane bound O-acyl transferase) family of membrane proteins contains a variety of acyltransferase enzymes. A conserved histidine has been suggested to be the active site residue []. The structure of MBOAT has been revealed [].This family includes Diacylglycerol O-acyltransferase 1 (DGAT1) and Lysophospholipid acyltransferase 7 (MBOAT7) from humans. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates []. It also functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders []. MBOAT7 participates in the regulation of triglyceride metabolism through the phosphatidylinositol acyl-chain remodeling regulation [].
Publication    
First Author: Helsley RN
Year: 2019
Journal: Elife
Title: Obesity-linked suppression of membrane-bound O-acyltransferase 7 (MBOAT7) drives non-alcoholic fatty liver disease.
Volume: 8
Protein
Organism: Mus musculus/domesticus
Length: 503  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 499  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 525  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 540  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 367  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 462  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 540  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 507  
Fragment?: false
Publication
First Author: Ma D
Year: 2018
Journal: Nature
Title: Crystal structure of a membrane-bound O-acyltransferase.
Volume: 562
Issue: 7726
Pages: 286-290
Protein
Organism: Mus musculus/domesticus
Length: 498  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 498  
Fragment?: false
Publication
First Author: Hofmann K
Year: 2000
Journal: Trends Biochem Sci
Title: A superfamily of membrane-bound O-acyltransferases with implications for wnt signaling.
Volume: 25
Issue: 3
Pages: 111-2