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Search results 201 to 236 out of 236 for Rps6ka3

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Type Details Score
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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UniProt Feature
UniProt Feature
Begin: 251
Description: Phosphoserine; by RPS6KA3
Type: modified residue
End: 251
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UniProt Feature
UniProt Feature
Begin: 334
Description: Phosphoserine; by RPS6KA3
Type: modified residue
End: 334
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UniProt Feature
UniProt Feature
Begin: 1120
Description: Phosphoserine; by RPS6KA3
Type: modified residue
End: 1120
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UniProt Feature
UniProt Feature
Begin: 1147
Description: Phosphoserine; by RPS6KA3
Type: modified residue
End: 1147
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UniProt Feature
UniProt Feature
Begin: 289
Description: Phosphoserine; by RPS6KA1 and RPS6KA3
Type: modified residue
End: 289
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UniProt Feature
UniProt Feature
Begin: 21
Description: Phosphoserine; by PKB and RPS6KA3
Type: modified residue
End: 21
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UniProt Feature
UniProt Feature
Begin: 21
Description: Phosphoserine; by PKB and RPS6KA3
Type: modified residue
End: 21
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UniProt Feature
UniProt Feature
Begin: 9
Description: Phosphoserine; by PKB/AKT1, RPS6KA3 and SGK3
Type: modified residue
End: 9
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UniProt Feature
UniProt Feature
Begin: 354
Description: Phosphoserine; by PKA, RPS6KA1 and RPS6KA3
Type: modified residue
End: 354
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UniProt Feature
UniProt Feature
Begin: 362
Description: Phosphoserine; by MAPK1, MAPK3 and RPS6KA3
Type: modified residue
End: 362
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Allele
Rps6ka3<em1Smoc> | MGI:7292115
Name: ribosomal protein S6 kinase polypeptide 3; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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UniProt Feature
UniProt Feature
Begin: 197
Description: Phosphothreonine; by CaMK1, PKB/AKT1, RPS6KA1, RPS6KA3 and PIM1
Type: modified residue
End: 197
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Strain
MGI:6429493 | C57BL/6J-Rps6ka3<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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DO Term
DOID:0112019 | non-syndromic X-linked intellectual disability 19
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HT Experiment
E-GEOD-22137 | Expression profiles of the hippocampus of Rsk2-KO mice
Series Id: GSE22137
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
25368387 | J:224308
First Author: Takada I
Year: 2015
Journal: Mol Cell Biol
Title: DGCR14 induces Il17a gene expression through the RORγ/BAZ1B/RSKS2 complex.
Volume: 35
Issue: 2
Pages: 344-55
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Publication
21061166 | -
First Author: Zeniou-Meyer M
Year: 2010
Journal: Cell Mol Neurobiol
Title: The Coffin-Lowry syndrome-associated protein RSK2 and neurosecretion.
Volume: 30
Issue: 8
Pages: 1401-6
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Publication
20074053 | -
First Author: Vitale N
Year: 2010
Journal: Biochem Soc Trans
Title: Synthesis of fusogenic lipids through activation of phospholipase D1 by GTPases and the kinase RSK2 is required for calcium-regulated exocytosis in neuroendocrine cells.
Volume: 38
Issue: Pt 1
Pages: 167-71
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Protein Domain
IPR041905 | RPS6KA3_C
Type: Domain
Description: This entry represents the C-terminal catalytic domain of ribosomal protein S6 kinase alpha-3.RPS6KA3 (also called RSK2) is expressed highly in the regions of the brain with high synaptic activity and plays a role in the maintenance and consolidation of excitatory synapses. It is a specific modulator of phospholipase D in calcium-regulated exocytosis []. Mutations in the RPS6KA3 gene cause Coffin-Lowry syndrome (CLS), a rare syndromic form of X-linked mental retardation characterised by growth and psychomotor retardation and skeletal abnormalities []. RSK2 is one of four RSK isoforms (RSK1-4) from distinct genes present in vertebrates.The most striking feature of RSKs is the presence of two functional and non-identical phosphotransferase domains []. RSKs contain an N-terminal kinase domain (NTD) that is characteristics of the AGC family and a C-terminal kinase domain (CTD) that is characteristics of the CAMK family. They are activated by signaling inputs from extracellular regulated kinase (ERK) and phosphoinositide dependent kinase 1 (PDK1). ERK phosphorylates and activates the CTD of RSK, serving as a docking site for PDK1, which phosphorylates and activates the NTD, which in turn phosphorylates all known RSK substrates. RSKs act as downstream effectors of mitogen-activated protein kinase (MAPK) and play key roles in mitogen-activated cell growth, differentiation, and survival [, , ].
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Publication
8392180 | -
First Author: Blenis J
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Signal transduction via the MAP kinases: proceed at your own RSK.
Volume: 90
Issue: 13
Pages: 5889-92
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Publication
8622665 | -
First Author: Fisher TL
Year: 1996
Journal: Mol Cell Biol
Title: Evidence for two catalytically active kinase domains in pp90rsk.
Volume: 16
Issue: 3
Pages: 1212-9
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Publication
22187936 | -
First Author: Romeo Y
Year: 2012
Journal: Biochem J
Title: Regulation and function of the RSK family of protein kinases.
Volume: 441
Issue: 2
Pages: 553-69
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Publication
18508509 | -
 
First Author: Carriere A
Year: 2008
Journal: Front Biosci
Title: The RSK factors of activating the Ras/MAPK signaling cascade.
Volume: 13
Pages: 4258-75
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Protein
P18654
Organism: Mus musculus/domesticus
Length: 740  
Fragment?: false
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Protein
A7E215
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: true
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Protein
B1AXN9
Organism: Mus musculus/domesticus
Length: 712  
Fragment?: false
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