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Search results 701 to 800 out of 819 for Cspg4

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Type Details Score
Publication
First Author: Hegedus B
Year: 2007
Journal: Cell Stem Cell
Title: Neurofibromatosis-1 regulates neuronal and glial cell differentiation from neuroglial progenitors in vivo by both cAMP- and Ras-dependent mechanisms.
Volume: 1
Issue: 4
Pages: 443-57
Publication
First Author: Niola F
Year: 2012
Journal: Nat Cell Biol
Title: Id proteins synchronize stemness and anchorage to the niche of neural stem cells.
Volume: 14
Issue: 5
Pages: 477-87
Publication
First Author: Hammond E
Year: 2015
Journal: J Neurosci
Title: The Wnt effector transcription factor 7-like 2 positively regulates oligodendrocyte differentiation in a manner independent of Wnt/β-catenin signaling.
Volume: 35
Issue: 12
Pages: 5007-22
Publication
First Author: Daneman R
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis.
Volume: 106
Issue: 2
Pages: 641-6
Publication      
First Author: Moyon S
Year: 2016
Journal: Cell Rep
Title: Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage.
Publication  
First Author: Li C
Year: 2020
Journal: Cells
Title: WNT5a-ROR Signaling Is Essential for Alveologenesis.
Volume: 9
Issue: 2
Publication
First Author: Arnold TD
Year: 2014
Journal: Development
Title: Excessive vascular sprouting underlies cerebral hemorrhage in mice lacking αVβ8-TGFβ signaling in the brain.
Volume: 141
Issue: 23
Pages: 4489-99
Publication  
First Author: Bachvarova V
Year: 2020
Journal: Matrix Biol
Title: Chondrocytes respond to an altered heparan sulfate composition with distinct changes of heparan sulfate structure and increased levels of chondroitin sulfate.
Volume: 93
Pages: 43-59
Publication
First Author: Zhang X
Year: 2023
Journal: iScience
Title: Bulk and mosaic deletions of Egfr reveal regionally defined gliogenesis in the developing mouse forebrain.
Volume: 26
Issue: 3
Pages: 106242
Publication  
First Author: Ju J
Year: 2016
Journal: Sci Rep
Title: Olig2 regulates Purkinje cell generation in the early developing mouse cerebellum.
Volume: 6
Pages: 30711
Publication
First Author: Joza S
Year: 2012
Journal: Am J Pathol
Title: Loss of semaphorin-neuropilin-1 signaling causes dysmorphic vascularization reminiscent of alveolar capillary dysplasia.
Volume: 181
Issue: 6
Pages: 2003-17
Publication
First Author: Trembley MA
Year: 2015
Journal: Development
Title: Myocardin-related transcription factors control the motility of epicardium-derived cells and the maturation of coronary vessels.
Volume: 142
Issue: 1
Pages: 21-30
Publication  
First Author: Luo PM
Year: 2023
Journal: Development
Title: Stromal netrin 1 coordinates renal arteriogenesis and mural cell differentiation.
Volume: 150
Issue: 22
Publication
First Author: Paul MH
Year: 2014
Journal: Cell Mol Life Sci
Title: Cardiac outflow tract development relies on the complex function of Sox4 and Sox11 in multiple cell types.
Volume: 71
Issue: 15
Pages: 2931-45
Publication
First Author: Fujiyama T
Year: 2018
Journal: Cell Rep
Title: Forebrain Ptf1a Is Required for Sexual Differentiation of the Brain.
Volume: 24
Issue: 1
Pages: 79-94
Publication      
First Author: Santander N
Year: 2020
Journal: J Clin Invest
Title: Lack of Flvcr2 impairs brain angiogenesis without affecting the blood-brain barrier.
Publication
First Author: Doeppner TR
Year: 2019
Journal: Mol Neurobiol
Title: Zbtb20 Regulates Developmental Neurogenesis in the Olfactory Bulb and Gliogenesis After Adult Brain Injury.
Volume: 56
Issue: 1
Pages: 567-582
Publication
First Author: Bernier-Latmani J
Year: 2015
Journal: J Clin Invest
Title: DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport.
Volume: 125
Issue: 12
Pages: 4572-86
Publication
First Author: Leferink PS
Year: 2018
Journal: Glia
Title: Affected astrocytes in the spinal cord of the leukodystrophy vanishing white matter.
Volume: 66
Issue: 4
Pages: 862-873
Publication
First Author: Guo M
Year: 2019
Journal: Nat Commun
Title: Single cell RNA analysis identifies cellular heterogeneity and adaptive responses of the lung at birth.
Volume: 10
Issue: 1
Pages: 37
Publication  
First Author: Wu J
Year: 2020
Journal: Gene Expr Patterns
Title: The spatiotemporal expression pattern of Syndecans in murine embryonic teeth.
Volume: 36
Pages: 119109
Publication    
First Author: Cole JD
Year: 2022
Journal: Elife
Title: Characterization of the neurogenic niche in the aging dentate gyrus using iterative immunofluorescence imaging.
Volume: 11
Publication
First Author: Rasile M
Year: 2022
Journal: EMBO J
Title: Maternal immune activation leads to defective brain-blood vessels and intracerebral hemorrhages in male offspring.
Volume: 41
Issue: 23
Pages: e111192
Publication
First Author: Jiang D
Year: 2020
Journal: J Comp Neurol
Title: Spatiotemporal gene expression patterns reveal molecular relatedness between retinal laminae.
Volume: 528
Issue: 5
Pages: 729-755
Publication
First Author: Reyahi A
Year: 2015
Journal: Dev Cell
Title: Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier.
Volume: 34
Issue: 1
Pages: 19-32
Publication  
First Author: Jiang M
Year: 2016
Journal: Nat Commun
Title: Regulation of PERK-eIF2α signalling by tuberous sclerosis complex-1 controls homoeostasis and survival of myelinating oligodendrocytes.
Volume: 7
Pages: 12185
Publication
First Author: Takemoto M
Year: 2006
Journal: EMBO J
Title: Large-scale identification of genes implicated in kidney glomerulus development and function.
Volume: 25
Issue: 5
Pages: 1160-74
Publication
First Author: Hellbach N
Year: 2014
Journal: Hum Mol Genet
Title: Neural deletion of Tgfbr2 impairs angiogenesis through an altered secretome.
Volume: 23
Issue: 23
Pages: 6177-90
Publication
First Author: Franco CA
Year: 2008
Journal: Dev Cell
Title: Serum response factor is required for sprouting angiogenesis and vascular integrity.
Volume: 15
Issue: 3
Pages: 448-61
Publication
First Author: Kim HT
Year: 2018
Journal: Nat Commun
Title: Myh10 deficiency leads to defective extracellular matrix remodeling and pulmonary disease.
Volume: 9
Issue: 1
Pages: 4600
Publication
First Author: Gerl K
Year: 2017
Journal: Am J Pathol
Title: Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development.
Volume: 187
Issue: 7
Pages: 1496-1511
Publication
First Author: Cullen M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier.
Volume: 108
Issue: 14
Pages: 5759-64
Publication  
First Author: Nechiporuk T
Year: 2016
Journal: Elife
Title: The REST remodeling complex protects genomic integrity during embryonic neurogenesis.
Volume: 5
Pages: e09584
Publication
First Author: Naba A
Year: 2012
Journal: Mol Cell Proteomics
Title: The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.
Volume: 11
Issue: 4
Pages: M111.014647
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Desai J
Year: 2006
Journal: Hum Mol Genet
Title: Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Volume: 15
Issue: 8
Pages: 1329-41
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Allele
Name: chondroitin sulfate proteoglycan 4; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Allele
Name: transgene insertion 1, Raghu Kalluri
Allele Type: Transgenic
Attribute String: Recombinase
Allele
Name: chondroitin sulfate proteoglycan 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
Strain
Attribute String: mutant strain, congenic, transgenic
Allele
Name: transgene insertion 1, Raghu Kalluri
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
Allele
Name: chondroitin sulfate proteoglycan 4; targeted mutation 1.1, Frank Kirchhoff
Allele Type: Targeted
Attribute String: Inducible, Null/knockout, Recombinase
Strain
Attribute String: transgenic, mutant strain, congenic
Strain
Attribute String: congenic, mutant strain, transgenic
Publication  
First Author: Huang M
Year: 2022
Journal: Cancer Lett
Title: Tumor perivascular cell-derived extracellular vesicles promote angiogenesis via the Gas6/Axl pathway.
Volume: 524
Pages: 131-143
Allele
Name: transgene insertion 1, Raghu Kalluri
Allele Type: Transgenic
Attribute String: Reporter
Allele
Name: transgene insertion H, Dwight E Bergles
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: congenic, mutant strain, transgenic
Allele
Name: transgene insertion, Berislav V Zlokovic
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Genotype
Symbol: Cspg4/Cspg4<+>
Background: involves: 129P2/OlaHsd * C57BL/6N
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Cspg4-cre)1Rkl/?
Background: involves: 129X1/SvJ * FVB
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Cooke VG
Year: 2012
Journal: Cancer Cell
Title: Pericyte depletion results in hypoxia-associated epithelial-to-mesenchymal transition and metastasis mediated by met signaling pathway.
Volume: 21
Issue: 1
Pages: 66-81
Strain
Attribute String: congenic, mutant strain, transgenic
Publication
First Author: Hughes EG
Year: 2013
Journal: Nat Neurosci
Title: Oligodendrocyte progenitors balance growth with self-repulsion to achieve homeostasis in the adult brain.
Volume: 16
Issue: 6
Pages: 668-76
Publication
First Author: Liu Y
Year: 2022
Journal: J Lipid Res
Title: Loss of ABCA8B decreases myelination by reducing oligodendrocyte precursor cells in mice.
Volume: 63
Issue: 1
Pages: 100147
Publication
First Author: Karmouch J
Year: 2017
Journal: Circ Res
Title: Distinct Cellular Basis for Early Cardiac Arrhythmias, the Cardinal Manifestation of Arrhythmogenic Cardiomyopathy, and the Skin Phenotype of Cardiocutaneous Syndromes.
Volume: 121
Issue: 12
Pages: 1346-1359
Publication
First Author: Nakashima K
Year: 2023
Journal: Commun Biol
Title: POT1a deficiency in mesenchymal niches perturbs B-lymphopoiesis.
Volume: 6
Issue: 1
Pages: 996
Publication
First Author: Fukushi J
Year: 2004
Journal: Mol Biol Cell
Title: NG2 proteoglycan promotes endothelial cell motility and angiogenesis via engagement of galectin-3 and alpha3beta1 integrin.
Volume: 15
Issue: 8
Pages: 3580-90
Publication
First Author: Li J
Year: 2003
Journal: Dev Biol
Title: The muscle integrin binding protein (MIBP) interacts with alpha7beta1 integrin and regulates cell adhesion and laminin matrix deposition.
Volume: 261
Issue: 1
Pages: 209-19
Protein Domain
Type: Family
Description: Integrins are the major metazoan receptors for cell adhesion to extracellular matrix proteins and, in vertebrates, also play important roles in certain cell-cell adhesions, make transmembrane connections to the cytoskeleton and activate many intracellular signalling pathways [, ]. An integrin receptor is a heterodimer composed of alpha and beta subunits. Each subunit crosses the membrane once, with most of the polypeptide residing in the extracellular space, and has twoshort cytoplasmic domains. Some members of this family have EGF repeats at the C terminus and also have a vWA domain inserted within the integrin domain at the N terminus.Most integrins recognise relatively short peptide motifs, and in general require an acidic amino acid to be present. Ligand specificity depends upon both the alpha and beta subunits []. There are at least 18 types of alpha and 8 types of beta subunits recognised in humans []. Each alpha subunit tends to associate only with one type of beta subunit, but there are exceptions to this rule []. Each association of alpha and beta subunits has its own binding specificity and signalling properties. Many integrins require activation on the cell surface before they can bind ligands. Integrins frequently intercommunicate, and binding at one integrin receptor activate or inhibit another.This entry represent integrin beta-1. Beta-1 integrin associates with alpha subunits to form receptor complexes that bind a variety of ligands. Integrins alpha-1/beta-1, alpha-2/beta-1, alpha-10/beta-1 and alpha-11/beta-1 are receptors for collagen. Integrins alpha-2/beta-1, alpha-3/beta-1, alpha-4/beta-1, alpha-5/beta-1, alpha-8/beta-1, alpha-10/beta-1, alpha-11/beta-1 and alpha-V/beta-1 are receptors for fibronectin. Integrin alpha-5/beta-1 is a receptor for fibrinogen. Integrin alpha-1/beta-1, alpha-2/beta-1, alpha-6/beta-1 and alpha-7/beta-1 are receptors for lamimin. Alpha7beta1 integrin regulates cell adhesion and laminin matrix deposition []. Integrin alpha-4/beta-1 is a receptor for VCAM1. Integrin alpha-9/beta-1 is a receptor for VCAM1, cytotactin and osteopontin. Integrin alpha-3/beta-1 is a receptor for epiligrin, thrombospondin and CSPG4 and has a role in endothelial cell motility and angiogenesis [].
Publication  
First Author: Chung SH
Year: 2015
Journal: Cell Death Dis
Title: The p38α mitogen-activated protein kinase is a key regulator of myelination and remyelination in the CNS.
Volume: 6
Pages: e1748
Publication
First Author: Hughes EG
Year: 2018
Journal: Nat Neurosci
Title: Myelin remodeling through experience-dependent oligodendrogenesis in the adult somatosensory cortex.
Volume: 21
Issue: 5
Pages: 696-706