Type |
Details |
Score |
Publication |
First Author: |
Bressler SL |
Year: |
1996 |
Journal: |
Hum Mol Genet |
Title: |
cDNA cloning and chromosome mapping of the human Fe65 gene: interaction of the conserved cytoplasmic domains of the human beta-amyloid precursor protein and its homologues with the mouse Fe65 protein. |
Volume: |
5 |
Issue: |
10 |
Pages: |
1589-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Poelaert BJ |
Year: |
2021 |
Journal: |
Cancers (Basel) |
Title: |
Amyloid Precursor-like Protein 2 Expression Increases during Pancreatic Cancer Development and Shortens the Survival of a Spontaneous Mouse Model of Pancreatic Cancer. |
Volume: |
13 |
Issue: |
7 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Yin T |
Year: |
2024 |
Journal: |
EMBO Rep |
Title: |
Functional BRI2-TREM2 interactions in microglia: implications for Alzheimer's and related dementias. |
Volume: |
25 |
Issue: |
3 |
Pages: |
1326-1360 |
|
•
•
•
•
•
|
Publication |
First Author: |
Goldsworthy M |
Year: |
2016 |
Journal: |
Diabetes |
Title: |
Haploinsufficiency of the Insulin Receptor in the Presence of a Splice-Site Mutation in Ppp2r2a Results in a Novel Digenic Mouse Model of Type 2 Diabetes. |
Volume: |
65 |
Issue: |
5 |
Pages: |
1434-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Garringer HJ |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Increased tau phosphorylation and tau truncation, and decreased synaptophysin levels in mutant BRI2/tau transgenic mice. |
Volume: |
8 |
Issue: |
2 |
Pages: |
e56426 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cowan CM |
Year: |
2001 |
Journal: |
J Neurosci |
Title: |
Caspases 3 and 9 send a pro-apoptotic signal from synapse to cell body in olfactory receptor neurons. |
Volume: |
21 |
Issue: |
18 |
Pages: |
7099-109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fleischer A |
Year: |
2002 |
Journal: |
Oncogene |
Title: |
Proapoptotic activity of ITM2B(s), a BH3-only protein induced upon IL-2-deprivation which interacts with Bcl-2. |
Volume: |
21 |
Issue: |
20 |
Pages: |
3181-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lopez JR |
Year: |
2008 |
Journal: |
J Neurochem |
Title: |
Increased intraneuronal resting [Ca2+] in adult Alzheimer's disease mice. |
Volume: |
105 |
Issue: |
1 |
Pages: |
262-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hohsfield LA |
Year: |
2014 |
Journal: |
Mol Cell Neurosci |
Title: |
Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models. |
Volume: |
63 |
|
Pages: |
83-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shibuya Y |
Year: |
2014 |
Journal: |
J Neurosci |
Title: |
Inhibiting ACAT1/SOAT1 in microglia stimulates autophagy-mediated lysosomal proteolysis and increases Aβ1-42 clearance. |
Volume: |
34 |
Issue: |
43 |
Pages: |
14484-501 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang S |
Year: |
2017 |
Journal: |
Front Aging Neurosci |
Title: |
Reducing the Levels of Akt Activation by PDK1 Knock-in Mutation Protects Neuronal Cultures against Synthetic Amyloid-Beta Peptides. |
Volume: |
9 |
|
Pages: |
435 |
|
•
•
•
•
•
|
Publication |
First Author: |
Medeiros R |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Loss of muscarinic M1 receptor exacerbates Alzheimer's disease-like pathology and cognitive decline. |
Volume: |
179 |
Issue: |
2 |
Pages: |
980-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xiang J |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer's disease pathologies. |
Volume: |
116 |
Issue: |
18 |
Pages: |
9094-9102 |
|
•
•
•
•
•
|
Publication |
First Author: |
Manczak M |
Year: |
2012 |
Journal: |
Hum Mol Genet |
Title: |
Abnormal interaction between the mitochondrial fission protein Drp1 and hyperphosphorylated tau in Alzheimer's disease neurons: implications for mitochondrial dysfunction and neuronal damage. |
Volume: |
21 |
Issue: |
11 |
Pages: |
2538-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Danielyan L |
Year: |
2020 |
Journal: |
EBioMedicine |
Title: |
Cell motility and migration as determinants of stem cell efficacy. |
Volume: |
60 |
|
Pages: |
102989 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim SH |
Year: |
2023 |
Journal: |
Autophagy |
Title: |
Endolysosomal impairment by binding of amyloid beta or MAPT/Tau to V-ATPase and rescue via the HYAL-CD44 axis in Alzheimer disease. |
Volume: |
19 |
Issue: |
8 |
Pages: |
2318-2337 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2021 |
Journal: |
Theranostics |
Title: |
A novel small-molecule PROTAC selectively promotes tau clearance to improve cognitive functions in Alzheimer-like models. |
Volume: |
11 |
Issue: |
11 |
Pages: |
5279-5295 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang H |
Year: |
2022 |
Journal: |
Theranostics |
Title: |
Adoptive therapy with amyloid-β specific regulatory T cells alleviates Alzheimer's disease. |
Volume: |
12 |
Issue: |
18 |
Pages: |
7668-7680 |
|
•
•
•
•
•
|
Publication |
First Author: |
Caberlotto L |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
Cross-disease analysis of Alzheimer's disease and type-2 Diabetes highlights the role of autophagy in the pathophysiology of two highly comorbid diseases. |
Volume: |
9 |
Issue: |
1 |
Pages: |
3965 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hargis KE |
Year: |
2017 |
Journal: |
Behav Brain Res |
Title: |
Transcriptional signatures of brain aging and Alzheimer's disease: What are our rodent models telling us? |
Volume: |
322 |
Issue: |
Pt B |
Pages: |
311-328 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bryleva EY |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
ACAT1 gene ablation increases 24(S)-hydroxycholesterol content in the brain and ameliorates amyloid pathology in mice with AD. |
Volume: |
107 |
Issue: |
7 |
Pages: |
3081-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ribe EM |
Year: |
2008 |
Journal: |
Biochem J |
Title: |
Mechanisms of neuronal death in disease: defining the models and the players. |
Volume: |
415 |
Issue: |
2 |
Pages: |
165-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fonseca MI |
Year: |
2011 |
Journal: |
J Neuroinflammation |
Title: |
Contribution of complement activation pathways to neuropathology differs among mouse models of Alzheimer's disease. |
Volume: |
8 |
Issue: |
1 |
Pages: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fuhrmann M |
Year: |
2010 |
Journal: |
Nat Neurosci |
Title: |
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease. |
Volume: |
13 |
Issue: |
4 |
Pages: |
411-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sabbir MG |
Year: |
2018 |
Journal: |
Front Mol Biosci |
Title: |
Loss of Ca2+/Calmodulin Dependent Protein Kinase Kinase 2 Leads to Aberrant Transferrin Phosphorylation and Trafficking: A Potential Biomarker for Alzheimer's Disease. |
Volume: |
5 |
|
Pages: |
99 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iyaswamy A |
Year: |
2020 |
Journal: |
Front Pharmacol |
Title: |
Yuan-Hu Zhi Tong Prescription Mitigates Tau Pathology and Alleviates Memory Deficiency in the Preclinical Models of Alzheimer's Disease. |
Volume: |
11 |
|
Pages: |
584770 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhao Y |
Year: |
2017 |
Journal: |
Neuron |
Title: |
Amyloid Beta Peptides Block New Synapse Assembly by Nogo Receptor-Mediated Inhibition of T-Type Calcium Channels. |
Volume: |
96 |
Issue: |
2 |
Pages: |
355-372.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Comerota MM |
Year: |
2019 |
Journal: |
Mol Neurobiol |
Title: |
Near Infrared Light Treatment Reduces Synaptic Levels of Toxic Tau Oligomers in Two Transgenic Mouse Models of Human Tauopathies. |
Volume: |
56 |
Issue: |
5 |
Pages: |
3341-3355 |
|
•
•
•
•
•
|
Publication |
First Author: |
Montgomery SL |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Ablation of TNF-RI/RII expression in Alzheimer's disease mice leads to an unexpected enhancement of pathology: implications for chronic pan-TNF-α suppressive therapeutic strategies in the brain. |
Volume: |
179 |
Issue: |
4 |
Pages: |
2053-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhutta MF |
Year: |
2013 |
Journal: |
Mamm Genome |
Title: |
Surveying the Down syndrome mouse model resource identifies critical regions responsible for chronic otitis media. |
Volume: |
24 |
Issue: |
11-12 |
Pages: |
439-45 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peiris H |
Year: |
2016 |
Journal: |
PLoS Genet |
Title: |
A Syntenic Cross Species Aneuploidy Genetic Screen Links RCAN1 Expression to β-Cell Mitochondrial Dysfunction in Type 2 Diabetes. |
Volume: |
12 |
Issue: |
5 |
Pages: |
e1006033 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schill EM |
Year: |
2019 |
Journal: |
JCI Insight |
Title: |
Down syndrome mouse models have an abnormal enteric nervous system. |
Volume: |
5 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Xing Z |
Year: |
2023 |
Journal: |
Hum Mol Genet |
Title: |
Dissection of a Down syndrome-associated trisomy to separate the gene dosage-dependent and -independent effects of an extra chromosome. |
Volume: |
32 |
Issue: |
13 |
Pages: |
2205-2218 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kubo A |
Year: |
2019 |
Journal: |
J Neurosci |
Title: |
Ectopic Expression Induces Abnormal Somatodendritic Distribution of Tau in the Mouse Brain. |
Volume: |
39 |
Issue: |
34 |
Pages: |
6781-6797 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dejanovic B |
Year: |
2022 |
Journal: |
Nat Aging |
Title: |
Complement C1q-dependent excitatory and inhibitory synapse elimination by astrocytes and microglia in Alzheimer's disease mouse models. |
Volume: |
2 |
Issue: |
9 |
Pages: |
837-850 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fowler AJ |
Year: |
2020 |
Journal: |
Hum Mol Genet |
Title: |
Discoidin Domain Receptor 1 is a therapeutic target for neurodegenerative diseases. |
Volume: |
29 |
Issue: |
17 |
Pages: |
2882-2898 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han HJ |
Year: |
2012 |
Journal: |
J Neurosci |
Title: |
Strain background influences neurotoxicity and behavioral abnormalities in mice expressing the tetracycline transactivator. |
Volume: |
32 |
Issue: |
31 |
Pages: |
10574-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bourdenx M |
Year: |
2021 |
Journal: |
Cell |
Title: |
Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome. |
Volume: |
184 |
Issue: |
10 |
Pages: |
2696-2714.e25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meyer-Luehmann M |
Year: |
2008 |
Journal: |
Nature |
Title: |
Rapid appearance and local toxicity of amyloid-beta plaques in a mouse model of Alzheimer's disease. |
Volume: |
451 |
Issue: |
7179 |
Pages: |
720-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Whitesell JD |
Year: |
2019 |
Journal: |
J Comp Neurol |
Title: |
Whole brain imaging reveals distinct spatial patterns of amyloid beta deposition in three mouse models of Alzheimer's disease. |
Volume: |
527 |
Issue: |
13 |
Pages: |
2122-2145 |
|
•
•
•
•
•
|
Publication |
First Author: |
Town T |
Year: |
2008 |
Journal: |
Nat Med |
Title: |
Blocking TGF-beta-Smad2/3 innate immune signaling mitigates Alzheimer-like pathology. |
Volume: |
14 |
Issue: |
6 |
Pages: |
681-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun X |
Year: |
2014 |
Journal: |
Cell Rep |
Title: |
miR-342-5p decreases ankyrin G levels in Alzheimer's disease transgenic mouse models. |
Volume: |
6 |
Issue: |
2 |
Pages: |
264-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi SW |
Year: |
2012 |
Journal: |
J Neurosci |
Title: |
No consistent bioenergetic defects in presynaptic nerve terminals isolated from mouse models of Alzheimer's disease. |
Volume: |
32 |
Issue: |
47 |
Pages: |
16775-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Burgess BL |
Year: |
2006 |
Journal: |
Neurobiol Dis |
Title: |
Elevated plasma triglyceride levels precede amyloid deposition in Alzheimer's disease mouse models with abundant A beta in plasma. |
Volume: |
24 |
Issue: |
1 |
Pages: |
114-27 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ferretti MT |
Year: |
2016 |
Journal: |
Brain Behav Immun |
Title: |
T-cell brain infiltration and immature antigen-presenting cells in transgenic models of Alzheimer's disease-like cerebral amyloidosis. |
Volume: |
54 |
|
Pages: |
211-225 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kass B |
Year: |
2022 |
Journal: |
Cell Rep Med |
Title: |
Aβ oligomer concentration in mouse and human brain and its drug-induced reduction ex vivo. |
Volume: |
3 |
Issue: |
5 |
Pages: |
100630 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alvarez-Vergara MI |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
Non-productive angiogenesis disassembles Aß plaque-associated blood vessels. |
Volume: |
12 |
Issue: |
1 |
Pages: |
3098 |
|
•
•
•
•
•
|
Publication |
First Author: |
Angulo SL |
Year: |
2017 |
Journal: |
Neurobiol Dis |
Title: |
Tau and amyloid-related pathologies in the entorhinal cortex have divergent effects in the hippocampal circuit. |
Volume: |
108 |
|
Pages: |
261-276 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reinders NR |
Year: |
2016 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Amyloid-β effects on synapses and memory require AMPA receptor subunit GluA3. |
Volume: |
113 |
Issue: |
42 |
Pages: |
E6526-E6534 |
|
•
•
•
•
•
|
Publication |
First Author: |
Le Pichon CE |
Year: |
2017 |
Journal: |
Sci Transl Med |
Title: |
Loss of dual leucine zipper kinase signaling is protective in animal models of neurodegenerative disease. |
Volume: |
9 |
Issue: |
403 |
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cx3cr1/Cx3cr1 Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/? Tg(Thy1-YFP)HJrs/? |
Background: |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Cx3cr1/Cx3cr1<+> Psen1/Psen1 Tg(APPSwe,tauP301L)1Lfa/? Tg(Thy1-YFP)HJrs/? |
Background: |
involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 85, David R Borchelt |
Allele Type: |
Transgenic |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Transgene |
Type: |
transgene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Tg(CMV-IghvaD11)DCat/? Tg(CMV-IgkvaD11)ACat/? |
Background: |
involves: C57BL/6 * SJL |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Martin GM |
Year: |
1998 |
Journal: |
Cell Mol Life Sci |
Title: |
Introduction: genetic determinants of mid- and late-life dementias. |
Volume: |
54 |
Issue: |
9 |
Pages: |
895-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cruts M |
Year: |
1998 |
Journal: |
Hum Mutat |
Title: |
Presenilin mutations in Alzheimer's disease. |
Volume: |
11 |
Issue: |
3 |
Pages: |
183-90 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
842
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
843
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
NIH Mouse Knockout Inventory |
Year: |
2004 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the NIH Mouse Knockout Inventory |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Sugino H |
Year: |
1997 |
Journal: |
Genomics |
Title: |
Genomic organization and chromosomal localization of the mouse telencephalin gene, a neuronal member of the ICAM family. |
Volume: |
43 |
Issue: |
2 |
Pages: |
209-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han C |
Year: |
2011 |
Journal: |
J Cell Physiol |
Title: |
Identification of heat shock protein 5, calnexin and integral membrane protein 2B as Adam7-interacting membrane proteins in mouse sperm. |
Volume: |
226 |
Issue: |
5 |
Pages: |
1186-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gu Z |
Year: |
2000 |
Journal: |
Cytogenet Cell Genet |
Title: |
The p53-inducible gene EI24/PIG8 localizes to human chromosome 11q23 and the proximal region of mouse chromosome 9. |
Volume: |
89 |
Issue: |
3-4 |
Pages: |
230-3 |
|
•
•
•
•
•
|
Transgene |
Type: |
transgene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Csf1/Csf1 |
Background: |
B6C3Fe a/a-Csf1/J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ldlr/Ldlr |
Background: |
B6.129S7-Ldlr |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Orre M |
Year: |
2014 |
Journal: |
Neurobiol Aging |
Title: |
Isolation of glia from Alzheimer's mice reveals inflammation and dysfunction. |
Volume: |
35 |
Issue: |
12 |
Pages: |
2746-2760 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamphuis W |
Year: |
2016 |
Journal: |
Biochim Biophys Acta |
Title: |
Transcriptional profiling of CD11c-positive microglia accumulating around amyloid plaques in a mouse model for Alzheimer's disease. |
Volume: |
1862 |
Issue: |
10 |
Pages: |
1847-60 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marinho D |
Year: |
2023 |
Journal: |
Aging Cell |
Title: |
Reduction of class I histone deacetylases ameliorates ER-mitochondria cross-talk in Alzheimer's disease. |
Volume: |
22 |
Issue: |
8 |
Pages: |
e13895 |
|
•
•
•
•
•
|
Publication |
First Author: |
Huang X |
Year: |
2021 |
Journal: |
Front Cell Dev Biol |
Title: |
Tetramethylpyrazine Improves Cognitive Impairment and Modifies the Hippocampal Proteome in Two Mouse Models of Alzheimer's Disease. |
Volume: |
9 |
|
Pages: |
632843 |
|
•
•
•
•
•
|
Publication |
First Author: |
Valny M |
Year: |
2018 |
Journal: |
Glia |
Title: |
A single-cell analysis reveals multiple roles of oligodendroglial lineage cells during post-ischemic regeneration. |
Volume: |
66 |
Issue: |
5 |
Pages: |
1068-1081 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liebmann T |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Three-Dimensional Study of Alzheimer's Disease Hallmarks Using the iDISCO Clearing Method. |
Volume: |
16 |
Issue: |
4 |
Pages: |
1138-1152 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lardenoije R |
Year: |
2018 |
Journal: |
Mol Cell Neurosci |
Title: |
Age-related epigenetic changes in hippocampal subregions of four animal models of Alzheimer's disease. |
Volume: |
86 |
|
Pages: |
1-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jadiya P |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer's disease. |
Volume: |
10 |
Issue: |
1 |
Pages: |
3885 |
|
•
•
•
•
•
|
Publication |
First Author: |
Clarke JR |
Year: |
2015 |
Journal: |
EMBO Mol Med |
Title: |
Alzheimer-associated Aβ oligomers impact the central nervous system to induce peripheral metabolic deregulation. |
Volume: |
7 |
Issue: |
2 |
Pages: |
190-210 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamphuis W |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
GFAP isoforms in adult mouse brain with a focus on neurogenic astrocytes and reactive astrogliosis in mouse models of Alzheimer disease. |
Volume: |
7 |
Issue: |
8 |
Pages: |
e42823 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song G |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Multimodal Coherent Imaging of Retinal Biomarkers of Alzheimer's Disease in a Mouse Model. |
Volume: |
10 |
Issue: |
1 |
Pages: |
7912 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roy DS |
Year: |
2016 |
Journal: |
Nature |
Title: |
Memory retrieval by activating engram cells in mouse models of early Alzheimer's disease. |
Volume: |
531 |
Issue: |
7595 |
Pages: |
508-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jiang H |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Live Neuron High-Content Screening Reveals Synaptotoxic Activity in Alzheimer Mouse Model Homogenates. |
Volume: |
10 |
Issue: |
1 |
Pages: |
3412 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou Q |
Year: |
2022 |
Journal: |
EBioMedicine |
Title: |
Human tau accumulation promotes glycogen synthase kinase-3β acetylation and thus upregulates the kinase: A vicious cycle in Alzheimer neurodegeneration. |
Volume: |
78 |
|
Pages: |
103970 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lacomme M |
Year: |
2022 |
Journal: |
Sci Adv |
Title: |
Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models. |
Volume: |
8 |
Issue: |
42 |
Pages: |
eabm4295 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hamilton A |
Year: |
2016 |
Journal: |
Cell Rep |
Title: |
Chronic Pharmacological mGluR5 Inhibition Prevents Cognitive Impairment and Reduces Pathogenesis in an Alzheimer Disease Mouse Model. |
Volume: |
15 |
Issue: |
9 |
Pages: |
1859-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chow HM |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
CDK5 activator protein p25 preferentially binds and activates GSK3β. |
Volume: |
111 |
Issue: |
45 |
Pages: |
E4887-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Haas LT |
Year: |
2017 |
Journal: |
Cell Rep |
Title: |
Silent Allosteric Modulation of mGluR5 Maintains Glutamate Signaling while Rescuing Alzheimer's Mouse Phenotypes. |
Volume: |
20 |
Issue: |
1 |
Pages: |
76-88 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen M |
Year: |
2021 |
Journal: |
Mol Neurodegener |
Title: |
Enhancing GABAergic signaling ameliorates aberrant gamma oscillations of olfactory bulb in AD mouse models. |
Volume: |
16 |
Issue: |
1 |
Pages: |
14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu L |
Year: |
2021 |
Journal: |
Aging Cell |
Title: |
Therapeutic efficacy of novel memantine nitrate MN-08 in animal models of Alzheimer's disease. |
Volume: |
20 |
Issue: |
6 |
Pages: |
e13371 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ben Haim L |
Year: |
2015 |
Journal: |
J Neurosci |
Title: |
The JAK/STAT3 pathway is a common inducer of astrocyte reactivity in Alzheimer's and Huntington's diseases. |
Volume: |
35 |
Issue: |
6 |
Pages: |
2817-29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jan A |
Year: |
2017 |
Journal: |
Acta Neuropathol |
Title: |
eEF2K inhibition blocks Aβ42 neurotoxicity by promoting an NRF2 antioxidant response. |
Volume: |
133 |
Issue: |
1 |
Pages: |
101-119 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chakravarthy B |
Year: |
2013 |
Journal: |
J Neurochem |
Title: |
A synthetic peptide corresponding to a region of the human pericentriolar material 1 (PCM-1) protein binds β-amyloid (Aβ1-42 ) oligomers. |
Volume: |
126 |
Issue: |
3 |
Pages: |
415-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fang EF |
Year: |
2019 |
Journal: |
Nat Neurosci |
Title: |
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease. |
Volume: |
22 |
Issue: |
3 |
Pages: |
401-412 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wei Y |
Year: |
2018 |
Journal: |
Cell Death Dis |
Title: |
Oxidation of KCNB1 channels in the human brain and in mouse model of Alzheimer's disease. |
Volume: |
9 |
Issue: |
8 |
Pages: |
820 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao FJ |
Year: |
2021 |
Journal: |
Acta Neuropathol Commun |
Title: |
Forebrain Shh overexpression improves cognitive function and locomotor hyperactivity in an aneuploid mouse model of Down syndrome and its euploid littermates. |
Volume: |
9 |
Issue: |
1 |
Pages: |
137 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sheppard K |
Year: |
2022 |
Journal: |
Cell Rep |
Title: |
Stride-level analysis of mouse open field behavior using deep-learning-based pose estimation. |
Volume: |
38 |
Issue: |
2 |
Pages: |
110231 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu H |
Year: |
2023 |
Journal: |
PLoS Biol |
Title: |
DSCAM gene triplication causes excessive GABAergic synapses in the neocortex in Down syndrome mouse models. |
Volume: |
21 |
Issue: |
4 |
Pages: |
e3002078 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang L |
Year: |
2012 |
Journal: |
Bioeng Bugs |
Title: |
Genetic analysis of Down syndrome facilitated by mouse chromosome engineering. |
Volume: |
3 |
Issue: |
1 |
Pages: |
8-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adorno M |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Usp16 modulates Wnt signaling in primary tissues through Cdkn2a regulation. |
Volume: |
8 |
Issue: |
1 |
Pages: |
17506 |
|
•
•
•
•
•
|