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Search results 501 to 598 out of 598 for Wnk1

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Type Details Score
Publication  
First Author: Zhang J
Year: 2016
Journal: Sci Rep
Title: Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Volume: 6
Pages: 35986
Publication
First Author: Jensen P
Year: 2004
Journal: Brain Res Mol Brain Res
Title: A neurogenomics approach to gene expression analysis in the developing brain.
Volume: 132
Issue: 2
Pages: 116-27
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Protein
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: true
UniProt Feature
Begin: 371
Description: Phosphoserine; by WNK1 and WNK4
Type: modified residue
End: 371
Protein
Organism: Mus musculus/domesticus
Length: 2377  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 788  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2635  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2128  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 135  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2626  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 2195  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 85  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 200  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 433  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 67  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 407  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 252  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 238  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 213  
Fragment?: true
Publication
First Author: Subramanya AR
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform.
Volume: 290
Issue: 3
Pages: F619-24
Interaction Experiment
Description: Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.
Publication
First Author: Delaloy C
Year: 2008
Journal: Hypertension
Title: Deletion of WNK1 first intron results in misregulation of both isoforms in renal and extrarenal tissues.
Volume: 52
Issue: 6
Pages: 1149-54
Allele
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Chou-Long Huang
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence
HT Experiment  
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
Publication  
First Author: Zeng G
Year: 2005
Journal: Gene
Title: Expression of the mouse WNK1 gene in correlation with ganglioside GD3 and functional analysis of the mouse WNK1 promoter.
Volume: 344
Pages: 233-9
DO Term
Allele
Name: kelch-like 3; targeted mutation 1.1, Eisei Sohara
Allele Type: Targeted
Attribute String: Not Specified
Publication
First Author: Lafreniere RG
Year: 2004
Journal: Am J Hum Genet
Title: Identification of a novel gene (HSN2) causing hereditary sensory and autonomic neuropathy type II through the Study of Canadian Genetic Isolates.
Volume: 74
Issue: 5
Pages: 1064-73
Publication
First Author: Susa K
Year: 2017
Journal: Biochem Biophys Res Commun
Title: WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3.
Volume: 491
Issue: 3
Pages: 727-732
Genotype
Symbol: Klhl3/Klhl3<+>
Background: involves: C57BL/6
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Klhl3/Klhl3
Background: involves: C57BL/6
Zygosity: hm
Has Mutant Allele: true
Publication  
First Author: Sasaki E
Year: 2017
Journal: Mol Cell Biol
Title: KLHL3 Knockout Mice Reveal the Physiological Role of KLHL3 and the Pathophysiology of Pseudohypoaldosteronism Type II Caused by Mutant KLHL3.
Volume: 37
Issue: 7
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Kdr/Kdr<+> Wnk1/Wnk1
Background: involves: 129S1/Sv * 129S5/SvEvBrd
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Park S
Year: 2013
Journal: Gastroenterology
Title: Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice.
Volume: 145
Issue: 1
Pages: 232-41
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Wnk1/Wnk1 Tg(Tek-cre)12Flv/?
Background: involves: 129S5/SvEvBrd * C3H * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Wnk1/Wnk1 Edil3/Edil3<+>
Background: involves: 129S5/SvEvBrd * C57BL/6 * CBA
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Boyd-Shiwarski CR
Year: 2022
Journal: Cell
Title: WNK kinases sense molecular crowding and rescue cell volume via phase separation.
Volume: 185
Issue: 24
Pages: 4488-4506.e20
Publication
First Author: Yang SS
Year: 2007
Journal: Cell Metab
Title: Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model.
Volume: 5
Issue: 5
Pages: 331-44
Publication
First Author: Chiga M
Year: 2008
Journal: Kidney Int
Title: Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone.
Volume: 74
Issue: 11
Pages: 1403-9
Publication
First Author: Richards J
Year: 2014
Journal: J Biol Chem
Title: A role for the circadian clock protein Per1 in the regulation of the NaCl co-transporter (NCC) and the with-no-lysine kinase (WNK) cascade in mouse distal convoluted tubule cells.
Volume: 289
Issue: 17
Pages: 11791-806
Publication
First Author: Wilson FH
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.
Volume: 100
Issue: 2
Pages: 680-4
Publication
First Author: Yang CL
Year: 2007
Journal: J Clin Invest
Title: The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.
Volume: 117
Issue: 11
Pages: 3403-11
Publication
First Author: Al-Qusairi L
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.
Volume: 311
Issue: 2
Pages: F330-42
Publication
First Author: Oi K
Year: 2012
Journal: Biol Open
Title: A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo.
Volume: 1
Issue: 2
Pages: 120-7
Publication  
First Author: Takahashi D
Year: 2014
Journal: Biosci Rep
Title: WNK4 is the major WNK positively regulating NCC in the mouse kidney.
Volume: 34
Issue: 3
Publication      
First Author: Chen JC
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: WNK4 kinase is a physiological intracellular chloride sensor.
Publication
First Author: Al-Qusairi L
Year: 2017
Journal: J Am Soc Nephrol
Title: Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion.
Volume: 28
Issue: 8
Pages: 2431-2442
Publication
First Author: Lin CM
Year: 2019
Journal: FASEB J
Title: Generation and analysis of a mouse model of pseudohypoaldosteronism type II caused by KLHL3 mutation in BTB domain.
Volume: 33
Issue: 1
Pages: 1051-1061
Publication  
First Author: Chen B
Year: 2023
Journal: Neurobiol Dis
Title: Activation of Swell1 in microglia suppresses neuroinflammation and reduces brain damage in ischemic stroke.
Volume: 176
Pages: 105936
Publication
First Author: Rinehart J
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: WNK3 kinase is a positive regulator of NKCC2 and NCC, renal cation-Cl- cotransporters required for normal blood pressure homeostasis.
Volume: 102
Issue: 46
Pages: 16777-82
Publication
First Author: Zhou B
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: WNK4 inhibits NCC protein expression through MAPK ERK1/2 signaling pathway.
Volume: 302
Issue: 5
Pages: F533-9
Publication
First Author: Xu B
Year: 2000
Journal: J Biol Chem
Title: WNK1, a novel mammalian serine/threonine protein kinase lacking the catalytic lysine in subdomain II.
Volume: 275
Issue: 22
Pages: 16795-801
Publication
First Author: Hengl T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Molecular components of signal amplification in olfactory sensory cilia.
Volume: 107
Issue: 13
Pages: 6052-7
Publication
First Author: Fulford L
Year: 2016
Journal: Sci Signal
Title: The transcription factor FOXF1 promotes prostate cancer by stimulating the mitogen-activated protein kinase ERK5.
Volume: 9
Issue: 427
Pages: ra48
Publication
First Author: Abdel Khalek W
Year: 2019
Journal: J Am Soc Nephrol
Title: Severe Arterial Hypertension from Cullin 3 Mutations Is Caused by Both Renal and Vascular Effects.
Volume: 30
Issue: 5
Pages: 811-823
Publication
First Author: Large MJ
Year: 2014
Journal: PLoS Genet
Title: The epidermal growth factor receptor critically regulates endometrial function during early pregnancy.
Volume: 10
Issue: 6
Pages: e1004451
Publication  
First Author: Tomilin VN
Year: 2021
Journal: Cells
Title: With-No-Lysine Kinase 1 (WNK1) Augments TRPV4 Function in the Aldosterone-Sensitive Distal Nephron.
Volume: 10
Issue: 6
Publication
First Author: Mederle K
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Loss of WNK3 is compensated for by the WNK1/SPAK axis in the kidney of the mouse.
Volume: 304
Issue: 9
Pages: F1198-209
Publication
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 3
Pages: 205-18
Publication
First Author: Villén J
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Large-scale phosphorylation analysis of mouse liver.
Volume: 104
Issue: 5
Pages: 1488-93
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112