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Search results 101 to 190 out of 190 for Lypd6

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0.022s
Type Details Score
GXD Expression
Probe: MGI:7606321
Assay Type: RNA in situ
Annotation Date: 2024-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7606896
Age: embryonic day 12.5
Image: S5D 3
Note: Expression was variable along the rostral-caudal axis, stronger in the caudal region. Dorsal-ventral changes were noted, stronger in the ventral region.
Specimen Label: S5D 3
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:7606321
Assay Type: RNA in situ
Annotation Date: 2024-02-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691020
Pattern: Regionally restricted
Stage: TS20
Assay Id: MGI:7606896
Age: embryonic day 12.5
Image: S5D 4 Caudal
Note: Expression was variable along the rostral-caudal axis, stronger in the caudal region. Dorsal-ventral changes were noted, stronger in the ventral region.
Specimen Label: S5D 4 Caudal
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945692
Age: embryonic day 15.5
Image: g01237 E15.5
Specimen Label: g01237 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 7
Image: g01237 P7
Note: Expression was region specific and scattered.
Specimen Label: g01237 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 42
Image: g01237 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01237 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689619
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945692
Age: embryonic day 11.5
Image: g01237 E11.5
Specimen Label: g01237 E11.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5811427
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5823659
Age: embryonic day 11.5
Image: Lypd6_b18_E11.5_8NOV13
Note: Staining is similar to that observed at E10.5. At that time it was seen in the ear, somites, and presomitic mesoderm and/or trunk.
Specimen Label: Lypd6_b18_E11.5_8NOV13
Detected: true
Specimen Num: 9
GXD Expression
Probe: MGI:5811427
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603919
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:5823659
Age: embryonic day 11.5
Image: Lypd6_b18_E11.5b_8NOV13
Note: Staining is similar to that observed at E10.5. At that time it was seen in the ear, somites, and presomitic mesoderm and/or trunk.
Specimen Label: Lypd6_b18_E11.5b_8NOV13
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:5811427
Assay Type: RNA in situ
Annotation Date: 2017-02-09
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3116917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5823659
Age: embryonic day 10.5
Image: Lypd6_b18_E10.5a_3JULY13_JL
Specimen Label: Lypd6_b18_E10.5a_3JULY13_JL
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 7
Image: g01237 P7
Specimen Label: g01237 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267328
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 42
Image: g01237 Adult
Specimen Label: g01237 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870435
Specimen Label: UC Davis_1870435
Detected: true
Specimen Num: 7
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870416
Specimen Label: UC Davis_1870416
Detected: true
Specimen Num: 12
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1718528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870417
Specimen Label: UC Davis_1870417
Detected: true
Specimen Num: 13
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1918028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870428
Note: vesicular gland
Specimen Label: UC Davis_1870428
Detected: true
Specimen Num: 24
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870418
Specimen Label: UC Davis_1870418
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 7
Image: g01237 P7
Specimen Label: g01237 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 42
Image: g01237 Adult
Specimen Label: g01237 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870421
Specimen Label: UC Davis_1870421
Detected: true
Specimen Num: 17
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1928728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870422
Specimen Label: UC Davis_1870422
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609219
Pattern: Widespread
Stage: TS19
Assay Id: MGI:4945692
Age: embryonic day 11.5
Image: g01237 E11.5
Specimen Label: g01237 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 7
Image: g01237 P7
Specimen Label: g01237 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 42
Image: g01237 Adult
Specimen Label: g01237 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870429
Specimen Label: UC Davis_1870429
Detected: true
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1683328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870430
Specimen Label: UC Davis_1870430
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 7
Image: g01237 P7
Note: Expression was region specific and scattered.
Specimen Label: g01237 P7
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 42
Image: g01237 Adult
Specimen Label: g01237 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:7423834
Assay Type: RNA in situ
Annotation Date: 2023-01-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3561422
Stage: TS22
Assay Id: MGI:7424932
Age: embryonic day 13.5
Image: S11 - E13.5
Note: The ONL-OECs lack expression.
Specimen Label: S11 - E13.5
Detected: false
Specimen Num: 3
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945692
Age: embryonic day 15.5
Image: g01237 E15.5
Specimen Label: g01237 E15.5
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 7
Image: g01237 P7
Note: Expression was region specific and scattered.
Specimen Label: g01237 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 42
Image: g01237 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01237 Adult
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3266523
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945692
Age: embryonic day 15.5
Image: g01237 E15.5
Specimen Label: g01237 E15.5
Detected: true
Specimen Num: 2
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870419
Specimen Label: UC Davis_1870419
Detected: true
Specimen Num: 15
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1929028
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870420
Specimen Label: UC Davis_1870420
Detected: true
Specimen Num: 16
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:3276428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870431
Specimen Label: UC Davis_1870431
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4945692
Age: embryonic day 15.5
Image: g01237 E15.5
Note: Expression was region specific and scattered.
Specimen Label: g01237 E15.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Widespread
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 7
Image: g01237 P7
Specimen Label: g01237 P7
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:4884887
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1757728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:4945692
Age: postnatal day 42
Image: g01237 Adult
Note: Expression was region specific and scattered.
Specimen Label: g01237 Adult
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:7466947
Assay Type: RNA in situ
Annotation Date: 2023-04-28
Strength: Absent
Sex: Female
Emaps: EMAPS:1738319
Stage: TS19
Assay Id: MGI:7467147
Age: embryonic day 11.5
Note: There is no expression in somatic cells.
Specimen Label: 11.5 dpc - not shown
Detected: false
Specimen Num: 7
GXD Expression  
Probe: MGI:7423834
Assay Type: RNA in situ
Annotation Date: 2023-01-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1779720
Stage: TS20
Assay Id: MGI:7424932
Age: embryonic day 11.5
Image: S11 - E11.5
Note: The mucosal OECs lack expression.
Specimen Label: S11 - E11.5
Detected: false
Specimen Num: 2
GXD Expression  
Probe: MGI:7423834
Assay Type: RNA in situ
Annotation Date: 2023-01-10
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1779722
Stage: TS22
Assay Id: MGI:7424932
Age: embryonic day 13.5
Image: S11 - E13.5
Note: The mucosal OECs lack expression.
Specimen Label: S11 - E13.5
Detected: false
Specimen Num: 3
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870423
Specimen Label: UC Davis_1870423
Detected: true
Specimen Num: 19
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870424
Specimen Label: UC Davis_1870424
Detected: true
Specimen Num: 20
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Male
Emaps: EMAPS:1868228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6692676
Age: postnatal adult
Image: UC Davis_1870425
Specimen Label: UC Davis_1870425
Detected: true
Specimen Num: 21
Publication  
First Author: Yook C
Year: 2019
Journal: Front Mol Neurosci
Title: A TBR1-K228E Mutation Induces Tbr1 Upregulation, Altered Cortical Distribution of Interneurons, Increased Inhibitory Synaptic Transmission, and Autistic-Like Behavioral Deficits in Mice.
Volume: 12
Pages: 241
Publication
First Author: Chen H
Year: 2012
Journal: PLoS One
Title: Identification of novel markers of mouse fetal ovary development.
Volume: 7
Issue: 7
Pages: e41683
Publication  
First Author: Moreau MX
Year: 2021
Journal: Development
Title: Single-cell transcriptomics of the early developing mouse cerebral cortex disentangle the spatial and temporal components of neuronal fate acquisition.
Volume: 148
Issue: 14
Publication
First Author: Gineste C
Year: 2013
Journal: Neuromuscul Disord
Title: In vivo and in vitro investigations of heterozygous nebulin knock-out mice disclose a mild skeletal muscle phenotype.
Volume: 23
Issue: 4
Pages: 357-69
Publication
First Author: Perera SN
Year: 2020
Journal: Glia
Title: Insights into olfactory ensheathing cell development from a laser-microdissection and transcriptome-profiling approach.
Volume: 68
Issue: 12
Pages: 2550-2584
Publication
First Author: Schilling K
Year: 2009
Journal: Cerebellum
Title: The treasury of the commons: making use of public gene expression resources to better characterize the molecular diversity of inhibitory interneurons in the cerebellar cortex.
Volume: 8
Issue: 4
Pages: 477-89
Publication
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
Publication
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
Publication      
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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First Author: Bairoch A
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Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Arvaniti M
Year: 2016
Journal: J Neurochem
Title: Functional interaction between Lypd6 and nicotinic acetylcholine receptors.
Volume: 138
Issue: 6
Pages: 806-20
Publication
First Author: Ochoa V
Year: 2016
Journal: FASEB J
Title: The prototoxin LYPD6B modulates heteromeric α3β4-containing nicotinic acetylcholine receptors, but not α7 homomers.
Volume: 30
Issue: 3
Pages: 1109-19
Protein Domain
Type: Family
Description: This entry includes Ly6/PLAUR domain-containing protein 6 and Ly6/PLAUR domain-containing protein 6B (LYPD6/6B). They are prototoxins that belong to a larger family known as Ly-6/urokinase plasminogen activator receptor (Ly6/uPAR). They have 8-10 conserved cysteine residues that allow for the formation of disulfide bonds, constraining the protein to the 3-fingered motif secondary structure [].Ly6/PLAUR domain-containing protein 6 (LYPD6) is a higher eukaryotic protein expressed in neurons. It modulates nicotinic acetylcholine receptors by selectively increasing Ca2+-influx through this ion channel []. LYPD6 carries an LU protein domain - about 80 amino acids long characterised by a conserved pattern of 10 cysteine residues []. It is a positive feedback regulator of Wnt/beta-catenin signalling, e.g. for patterning of the mesoderm and neuroectoderm in zebrafish gastrulation, where Lypd6 is GPI-anchored to the plasma-membrane and interacts with the Wnt receptor Frizzled8 and the co-receptor Lrp6 [].LYPD6B has been shown to modulate heteromeric alpha3beta4-containing nicotinic acetylcholine receptors [].
Protein
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: false
Publication
First Author: Jensen MM
Year: 2015
Journal: Neurobiol Aging
Title: Prostate stem cell antigen interacts with nicotinic acetylcholine receptors and is affected in Alzheimer's disease.
Volume: 36
Issue: 4
Pages: 1629-1638