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Search results 301 to 322 out of 322 for Nop58

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0.018s

Type

Details

Score

Publication

21326211 | -

First Author:	Finkbeiner E
Year:	2011
Journal:	EMBO J
Title:	The SUMO system controls nucleolar partitioning of a novel mammalian ribosome biogenesis complex.
Volume:	30
Issue:	6
Pages:	1067-78

•

Publication

20797632 | -

First Author:	Westman BJ
Year:	2010
Journal:	Mol Cell
Title:	A proteomic screen for nucleolar SUMO targets shows SUMOylation modulates the function of Nop5/Nop58.
Volume:	39
Issue:	4
Pages:	618-31

•

Publication

16738315 | -

First Author:	Di Bacco A
Year:	2006
Journal:	Mol Cell Biol
Title:	The SUMO-specific protease SENP5 is required for cell division.
Volume:	26
Issue:	12
Pages:	4489-98

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Publication

17341580 | -

First Author:	Zunino R
Year:	2007
Journal:	J Cell Sci
Title:	The SUMO protease SENP5 is required to maintain mitochondrial morphology and function.
Volume:	120
Issue:	Pt 7
Pages:	1178-88

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Publication

19411255 | -

First Author:	Zunino R
Year:	2009
Journal:	J Biol Chem
Title:	Translocation of SenP5 from the nucleoli to the mitochondria modulates DRP1-dependent fission during mitosis.
Volume:	284
Issue:	26
Pages:	17783-95

•

Publication

25128087 | J:225785

First Author:	Kim EY
Year:	2015
Journal:	J Mol Cell Cardiol
Title:	SENP5, a SUMO isopeptidase, induces apoptosis and cardiomyopathy.
Volume:	78

Pages:	154-64

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Publication

25984443 | -

First Author:	Federzoni EA
Year:	2015
Journal:	Leuk Res Rep
Title:	Linking the SUMO protease SENP5 to neutrophil differentiation of AML cells.
Volume:	4
Issue:	1
Pages:	32-5

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Protein Domain

IPR033465 | SENP5

Type:

Family

Description:

SENP5 peptidase (sentrin-specific peptidase 5, MEROPS identifier C48.008) is a deSUMOylating peptidase localized predominantly to the nucleolus. SENP5 releases the tag proteins SUMO-2 and -3 from conjugates, preferentially acting as an isopeptidase rather than an endopeptidase []. Simultaneous depletion of SENP3 and SENP5 results in enhanced SUMOylation of proteins such as RPL37A and GNL2, which are involved in the processing of pre-rRNA [], PELP1 and LAS1L, which are involved in the release of mature ribosomal particles [], and Nop58, which is a component of small nucleolar ribonucleoprotein (snoRNP) and SUMOlyation is required for binding of Nop58 to snoRNA to maintain nucleolar retention []. SENP5 depletion also affects mitotic progression, and cells arrest at the G2/M transition []. SENP5 is also involved in mitochondrial fusion and fission, because SUMOylated dynamin-1-like protein (Drp1), which is a mitochondrial fission factor, is a target for SENP5 []. DeSUMOylation of Drp1 is a contributory factor to cardiomyopathy []. During the G2/M transition stage of mitosis, SENP5 transiently locates to the mitochondrion []. SENP5 is also required for neutrophil differentiation, and the SNP5 gene is repressed in clinical acute myeloid leukemia [].

•

Protein

A0A087WP00

Organism:	Mus musculus/domesticus
Length:	195
Fragment?:	true

•

Protein

F7CHQ7

Organism:	Mus musculus/domesticus
Length:	222
Fragment?:	true

•

Protein

F6V095

Organism:	Mus musculus/domesticus
Length:	173
Fragment?:	true

•

Protein

A0A087WQ46

Organism:	Mus musculus/domesticus
Length:	213
Fragment?:	true

•

Protein

F6U250

Organism:	Mus musculus/domesticus
Length:	135
Fragment?:	true

•

Protein

A2APD7

Organism:	Mus musculus/domesticus
Length:	296
Fragment?:	true

•

Publication

12598892 | -

First Author:	Aittaleb M
Year:	2003
Journal:	Nat Struct Biol
Title:	Structure and function of archaeal box C/D sRNP core proteins.
Volume:	10
Issue:	4
Pages:	256-63

•

Publication

18259216 | -

First Author:	Haindl M
Year:	2008
Journal:	EMBO Rep
Title:	The nucleolar SUMO-specific protease SENP3 reverses SUMO modification of nucleophosmin and is required for rRNA processing.
Volume:	9
Issue:	3
Pages:	273-9

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Protein

Q9DBE9

Organism:	Mus musculus/domesticus
Length:	838
Fragment?:	false

•

Publication

17412961 | -

First Author:	Liu S
Year:	2007
Journal:	Science
Title:	Binding of the human Prp31 Nop domain to a composite RNA-protein platform in U4 snRNP.
Volume:	316
Issue:	5821
Pages:	115-20

•

Protein

Q6NXL6

Organism:	Mus musculus/domesticus
Length:	749
Fragment?:	false

•

Protein

F6S6C3

Organism:	Mus musculus/domesticus
Length:	607
Fragment?:	true

•

Protein

F7A4L2

Organism:	Mus musculus/domesticus
Length:	210
Fragment?:	true

•

Publication

15112237 | -

First Author:	Staub E
Year:	2004
Journal:	Bioessays
Title:	Insights into the evolution of the nucleolus by an analysis of its protein domain repertoire.
Volume:	26
Issue:	5
Pages:	567-81

•

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