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Search results 201 to 267 out of 267 for Bmp15

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Type Details Score
Publication
21047911 | J:182909
First Author: Sugiura K
Year: 2010
Journal: Mol Endocrinol
Title: Estrogen promotes the development of mouse cumulus cells in coordination with oocyte-derived GDF9 and BMP15.
Volume: 24
Issue: 12
Pages: 2303-14
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Publication
25416550 | J:218520
First Author: Grasa P
Year: 2015
Journal: FASEB J
Title: Oocytes lacking O-glycans alter follicle development and increase fertility by increasing follicle FSH sensitivity, decreasing apoptosis, and modifying GDF9:BMP15 expression.
Volume: 29
Issue: 2
Pages: 525-39
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Publication
12912906 | J:85054
First Author: Lan ZJ
Year: 2003
Journal: EMBO J
Title: GCNF-dependent repression of BMP-15 and GDF-9 mediates gamete regulation of female fertility.
Volume: 22
Issue: 16
Pages: 4070-81
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Publication
19480014 | J:200667
First Author: Monti M
Year: 2009
Journal: Mol Reprod Dev
Title: Oogenesis specific genes (Nobox, Oct4, Bmp15, Gdf9, Oogenesin1 and Oogenesin2) are differentially expressed during natural and gonadotropin-induced mouse follicular development.
Volume: 76
Issue: 10
Pages: 994-1003
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Publication
20382892 | J:162255
First Author: Su YQ
Year: 2010
Journal: Mol Endocrinol
Title: Mouse oocytes enable LH-induced maturation of the cumulus-oocyte complex via promoting EGF receptor-dependent signaling.
Volume: 24
Issue: 6
Pages: 1230-9
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Publication
12887271 | J:85566
First Author: Lin SY
Year: 2003
Journal: Reproduction
Title: Regulation of ovarian function by the TGF-beta superfamily and follistatin.
Volume: 126
Issue: 2
Pages: 133-48
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Publication
26267271 | J:226026
First Author: Deuve JL
Year: 2015
Journal: Epigenetics
Title: Antagonist Xist and Tsix co-transcription during mouse oogenesis and maternal Xist expression during pre-implantation development calls into question the nature of the maternal imprint on the X chromosome.
Volume: 10
Issue: 10
Pages: 931-42
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Publication
35104175 | J:324293
First Author: Gindi N
Year: 2022
Journal: Cell Cycle
Title: Fyn and argonaute 2 participate in maternal-mRNA degradation during mouse oocyte maturation.
Volume: 21
Issue: 8
Pages: 792-804
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Publication
22847922 | J:190579
First Author: Pangas SA
Year: 2012
Journal: Mol Reprod Dev
Title: Regulation of the ovarian reserve by members of the transforming growth factor beta family.
Volume: 79
Issue: 10
Pages: 666-79
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Publication
31657143 | J:282136
First Author: Kato Y
Year: 2019
Journal: EMBO Rep
Title: ELAVL2-directed RNA regulatory network drives the formation of quiescent primordial follicles.
Volume: 20
Issue: 12
Pages: e48251
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Publication
15326356 | J:92421
First Author: Rajkovic A
Year: 2004
Journal: Science
Title: NOBOX deficiency disrupts early folliculogenesis and oocyte-specific gene expression.
Volume: 305
Issue: 5687
Pages: 1157-9
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Publication
25810521 | J:221341
First Author: Lun MP
Year: 2015
Journal: J Neurosci
Title: Spatially heterogeneous choroid plexus transcriptomes encode positional identity and contribute to regional CSF production.
Volume: 35
Issue: 12
Pages: 4903-16
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Publication
24357321 | J:205485
First Author: Yu C
Year: 2013
Journal: Science
Title: CRL4 complex regulates mammalian oocyte survival and reprogramming by activation of TET proteins.
Volume: 342
Issue: 6165
Pages: 1518-21
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Publication
15342483 | J:108109
First Author: Oxburgh L
Year: 2004
Journal: Development
Title: TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population.
Volume: 131
Issue: 18
Pages: 4593-605
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Publication
30352686 | J:270543
First Author: Tanahashi H
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Deletion of Lrp4 increases the incidence of microphthalmia.
Volume: 506
Issue: 3
Pages: 478-484
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Publication
12666204 | J:82773
First Author: Dichmann DS
Year: 2003
Journal: Dev Dyn
Title: Expression and misexpression of members of the FGF and TGFbeta families of growth factors in the developing mouse pancreas.
Volume: 226
Issue: 4
Pages: 663-74
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Publication
16537572 | J:108241
First Author: Desai J
Year: 2006
Journal: Hum Mol Genet
Title: Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Volume: 15
Issue: 8
Pages: 1329-41
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Publication
21731673 | J:174767
First Author: Tang F
Year: 2011
Journal: PLoS One
Title: Deterministic and stochastic allele specific gene expression in single mouse blastomeres.
Volume: 6
Issue: 6
Pages: e21208
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Publication
10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
24952961 | J:215487
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
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Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
38427603 | J:346097
First Author: Liu Y
Year: 2024
Journal: Proc Natl Acad Sci U S A
Title: A rare germline BMP15 missense mutation causes hereditary ovarian immature teratoma in human.
Volume: 121
Issue: 10
Pages: e2310409121
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DO Term
DOID:0080494 | ovarian dysgenesis 2
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DO Term
DOID:0080861 | primary ovarian insufficiency 4
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Publication
10443672 | -
First Author: Aaltonen J
Year: 1999
Journal: J Clin Endocrinol Metab
Title: Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early folliculogenesis.
Volume: 84
Issue: 8
Pages: 2744-50
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Publication
10998422 | -
First Author: Otsuka F
Year: 2000
Journal: J Biol Chem
Title: Bone morphogenetic protein-15. Identification of target cells and biological functions.
Volume: 275
Issue: 50
Pages: 39523-8
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Protein Domain
IPR015923 | BMP-15
Type: Family
Description: The bone morphogenetic protein (BMP) is part of the transforming growth factor-beta superfamily. Transforming growth factor-beta (TGF-beta) is a multifunctional peptide that controls proliferation, differentiation and other functions in many cell types. TGF-beta-1 is a peptide of 112 amino acid residues derived by proteolytic cleavage from the C-terminal of a precursor protein.A number of proteins are known to be related to TGF-beta-1 [, ]. Proteins from the TGF-beta family are only active as homo- or heterodimer; the two chains being linked by a single disulphide bond. From X-ray studies of TGF-beta-2 [], it is known that all the other cysteines are involved in intrachain disulphide bonds. As shown in the following schematic representation, there are four disulphide bonds in the TGF-beta's and in inhibin beta chains, while the other members of lack the first bond.BMP-15 (or GDF-9B) has been identified by in the mouse and in humans []. BMP15 protein is encoded by 2 exons []. Homo sapiens (Human) GDF9B transcripts could be detected only in the gonads by RT-PCR analysis, and in situ hybridization studies indicated that GDF9B is not expressed in small primary follicles but rather in the oocytes of late primary follicles []. It was shown that BMP15 is a selective modulator of FSH function []. Male BMP-15 knockout mice are normal and fertile while the females demonstrate decreased ovulation and fertilization rate [].
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HT Experiment
E-GEOD-7225 | Transcription profiling of mouse cumulus cells from Bmp15-/- and Bmp15-/-Gdf9+/--DM animals
Series Id: GSE7225
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
30010909 | J:266539
First Author: Zhang D
Year: 2018
Journal: Hum Mol Genet
Title: Basonuclin 1 deficiency is a cause of primary ovarian insufficiency.
Volume: 27
Issue: 21
Pages: 3787-3800
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Publication
26388295 | J:250114
 
First Author: Tokuhiro K
Year: 2015
Journal: Sci Rep
Title: Calreticulin is required for development of the cumulus oocyte complex and female fertility.
Volume: 5
Pages: 14254
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Publication
16011810 | J:123873
 
First Author: Turk R
Year: 2005
Journal: BMC Genomics
Title: Muscle regeneration in dystrophin-deficient mdx mice studied by gene expression profiling.
Volume: 6
Pages: 98
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Publication
26040669 | J:224465
First Author: Sun T
Year: 2015
Journal: Biol Reprod
Title: Lats1 Deletion Causes Increased Germ Cell Apoptosis and Follicular Cysts in Mouse Ovaries.
Volume: 93
Issue: 1
Pages: 22
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Publication
18308851 | J:136039
First Author: McMahon HE
Year: 2008
Journal: Endocrinology
Title: Oocyte-specific overexpression of mouse bone morphogenetic protein-15 leads to accelerated folliculogenesis and an early onset of acyclicity in transgenic mice.
Volume: 149
Issue: 6
Pages: 2807-15
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Publication
19106224 | J:151812
First Author: Nicholls PK
Year: 2009
Journal: Endocrinology
Title: Growth differentiation factor 9 is a germ cell regulator of Sertoli cell function.
Volume: 150
Issue: 5
Pages: 2481-90
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Publication
25253739 | J:218422
First Author: Peng J
Year: 2014
Journal: Biol Reprod
Title: Amino acid 72 of mouse and human GDF9 mature domain is responsible for altered homodimer bioactivities but has subtle effects on GDF9:BMP15 heterodimer activities.
Volume: 91
Issue: 6
Pages: 142
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Protein
Q9Z0L4
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
Q3USZ3
Organism: Mus musculus/domesticus
Length: 392  
Fragment?: false
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Protein
Q3UWT0
Organism: Mus musculus/domesticus
Length: 310  
Fragment?: true
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Publication
25099774 | J:310290
First Author: Schneider A
Year: 2014
Journal: Age (Dordr)
Title: Effect of growth hormone receptor gene disruption and PMA treatment on the expression of genes involved in primordial follicle activation in mice ovaries.
Volume: 36
Issue: 4
Pages: 9701
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Publication
1575734 | -
First Author: Burt DW
Year: 1992
Journal: Biochem Biophys Res Commun
Title: Evolutionary grouping of the transforming growth factor-beta superfamily.
Volume: 184
Issue: 2
Pages: 590-5
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Publication
8199356 | -
First Author: Burt DW
Year: 1994
Journal: Prog Growth Factor Res
Title: Evolution of the transforming growth factor-beta superfamily.
Volume: 5
Issue: 1
Pages: 99-118
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Publication
1631557 | -
First Author: Daopin S
Year: 1992
Journal: Science
Title: Crystal structure of transforming growth factor-beta 2: an unusual fold for the superfamily.
Volume: 257
Issue: 5068
Pages: 369-73
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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