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Search results 1 to 100 out of 112 for Mgmt

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Category: Publication
Type Details Score
Publication
First Author: Sakumi K
Year: 1997
Journal: Cancer Res
Title: Methylnitrosourea-induced tumorigenesis in MGMT gene knockout mice.
Volume: 57
Issue: 12
Pages: 2415-8
Publication
First Author: Takagi Y
Year: 2003
Journal: DNA Repair (Amst)
Title: Roles of MGMT and MLH1 proteins in alkylation-induced apoptosis and mutagenesis.
Volume: 2
Issue: 10
Pages: 1135-46
Publication
First Author: Bugni JM
Year: 2009
Journal: Oncogene
Title: Alkylation-induced colon tumorigenesis in mice deficient in the Mgmt and Msh6 proteins.
Volume: 28
Issue: 5
Pages: 734-41
Publication
First Author: Qin X
Year: 1999
Journal: Carcinogenesis
Title: Transgenic expression of human MGMT blocks the hypersensitivity of PMS2-deficient mice to low dose MNU thymic lymphomagenesis.
Volume: 20
Issue: 9
Pages: 1667-73
Publication
First Author: Sandercock LE
Year: 2004
Journal: Oncogene
Title: Mutational-reporter transgenes rescued from mice lacking either Mgmt, or both Mgmt and Msh6 suggest that O6-alkylguanine-induced miscoding does not contribute to the spontaneous mutational spectrum.
Volume: 23
Issue: 35
Pages: 5931-40
Publication  
First Author: Lindahl T
Year: 1988
Journal: Annu Rev Biochem
Title: Regulation and expression of the adaptive response to alkylating agents.
Volume: 57
Pages: 133-57
Publication
First Author: Morohoshi F
Year: 1987
Journal: J Bacteriol
Title: Multiple species of Bacillus subtilis DNA alkyltransferase involved in the adaptive response to simple alkylating agents.
Volume: 169
Issue: 2
Pages: 587-92
Publication
First Author: Shiota S
Year: 1992
Journal: Biochemistry
Title: Characterization of cDNA encoding mouse DNA repair protein O6-methylguanine-DNA methyltransferase and high-level expression of the wild-type and mutant proteins in Escherichia coli.
Volume: 31
Issue: 7
Pages: 1897-903
Publication
First Author: Glassner BJ
Year: 1999
Journal: Mutagenesis
Title: DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents.
Volume: 14
Issue: 3
Pages: 339-47
Publication
First Author: Zhou ZQ
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Spontaneous hepatocellular carcinoma is reduced in transgenic mice overexpressing human O6- methylguanine-DNA methyltransferase.
Volume: 98
Issue: 22
Pages: 12566-71
Publication
First Author: Liu L
Year: 1996
Journal: Cancer Res
Title: Differential sensitivity of human and mouse alkyltransferase to O6-benzylguanine using a transgenic model.
Volume: 56
Issue: 8
Pages: 1880-5
Publication
First Author: Abdel-Fattah R
Year: 2006
Journal: Int J Cancer
Title: Methylation of the O6-methylguanine-DNA methyltransferase promoter suppresses expression in mouse skin tumors and varies with the tumor induction protocol.
Volume: 118
Issue: 3
Pages: 527-31
Publication
First Author: Hansen RJ
Year: 2007
Journal: Carcinogenesis
Title: Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice.
Volume: 28
Issue: 5
Pages: 1111-6
Publication
First Author: Fukushima S
Year: 2001
Journal: Mutat Res
Title: Possible involvement of O6-methylguanine formation and p53 dysfunction in mouse urinary bladder carcinogenesis.
Volume: 477
Issue: 1-2
Pages: 125-30
Publication
First Author: Roy R
Year: 1995
Journal: Carcinogenesis
Title: A comparative study of the biochemical properties of human and mouse recombinant O6-methylguanine-DNA methyltransferases.
Volume: 16
Issue: 2
Pages: 405-11
Publication
First Author: Dörsam B
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: PARP-1 protects against colorectal tumor induction, but promotes inflammation-driven colorectal tumor progression.
Volume: 115
Issue: 17
Pages: E4061-E4070
Publication
First Author: Nagasubramanian R
Year: 2008
Journal: Mutagenesis
Title: Survival and tumorigenesis in O6-methylguanine DNA methyltransferase-deficient mice following cyclophosphamide exposure.
Volume: 23
Issue: 5
Pages: 341-6
Publication
First Author: Wirtz S
Year: 2010
Journal: Carcinogenesis
Title: Both base excision repair and O6-methylguanine-DNA methyltransferase protect against methylation-induced colon carcinogenesis.
Volume: 31
Issue: 12
Pages: 2111-7
Publication
First Author: Kawate H
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Separation of killing and tumorigenic effects of an alkylating agent in mice defective in two of the DNA repair genes.
Volume: 95
Issue: 9
Pages: 5116-20
Publication
First Author: Kawate H
Year: 2000
Journal: Carcinogenesis
Title: A defect in a single allele of the Mlh1 gene causes dissociation of the killing and tumorigenic actions of an alkylating carcinogen in methyltransferase-deficient mice.
Volume: 21
Issue: 2
Pages: 301-5
Publication
First Author: Baran K
Year: 2017
Journal: Cell Death Differ
Title: The proline rich domain of p53 is dispensable for MGMT-dependent DNA repair and cell survival following alkylation damage.
Volume: 24
Issue: 11
Pages: 1925-1936
Publication
First Author: Fahrer J
Year: 2015
Journal: Carcinogenesis
Title: DNA repair by MGMT, but not AAG, causes a threshold in alkylation-induced colorectal carcinogenesis.
Volume: 36
Issue: 10
Pages: 1235-44
Publication
First Author: Dominick G
Year: 2017
Journal: Aging Cell
Title: mTOR regulates the expression of DNA damage response enzymes in long-lived Snell dwarf, GHRKO, and PAPPA-KO mice.
Volume: 16
Issue: 1
Pages: 52-60
Publication  
First Author: Schweer T
Year: 1998
Journal: J Biomol Struct Dyn
Title: Conditional liver-specific "knock-out" of the murine genes encoding 06-Alkylguanine-DNA Alkyltransferase (AGT) and AP-Endonuclease (APE)
Volume: 16
Pages: 180-1 (Abstr.)
Publication
First Author: Tsuzuki T
Year: 1996
Journal: Carcinogenesis
Title: Targeted disruption of the DNA repair methyltransferase gene renders mice hypersensitive to alkylating agent.
Volume: 17
Issue: 6
Pages: 1215-20
Publication
First Author: Shiraishi A
Year: 2000
Journal: Carcinogenesis
Title: Increased susceptibility to chemotherapeutic alkylating agents of mice deficient in DNA repair methyltransferase.
Volume: 21
Issue: 10
Pages: 1879-83
Publication
First Author: Kisby GE
Year: 2011
Journal: PLoS One
Title: The cycad genotoxin MAM modulates brain cellular pathways involved in neurodegenerative disease and cancer in a DNA damage-linked manner.
Volume: 6
Issue: 6
Pages: e20911
Publication
First Author: Santibanez-Koref M
Year: 1992
Journal: Mol Carcinog
Title: Isolation and partial characterization of murine O6-alkylguanine-DNA-alkyltransferase: comparative sequence and structural properties.
Volume: 5
Issue: 2
Pages: 161-9
Publication
First Author: Rouleau J
Year: 1992
Journal: J Biol Chem
Title: The mouse DNA methyltransferase 5'-region. A unique housekeeping gene promoter.
Volume: 267
Issue: 11
Pages: 7368-77
Publication
First Author: Devereux TR
Year: 1993
Journal: Mol Carcinog
Title: Comparison of pulmonary O6-methylguanine DNA adduct levels and Ki-ras activation in lung tumors from resistant and susceptible mouse strains.
Volume: 8
Issue: 3
Pages: 177-85
Publication  
First Author: Holdener BC
Year: 1993
Journal: Mamm Genome
Title: Encyclopedia of the mouse genome III. October 1993. Mouse chromosome 7.
Volume: 4 Spec No
Pages: S110-20
Publication
First Author: Kawate H
Year: 1995
Journal: Carcinogenesis
Title: Mouse methyltransferase for repair of O6-methylguanine and O4-methylthymine in DNA.
Volume: 16
Issue: 7
Pages: 1595-602
Publication
First Author: Graziani G
Year: 1995
Journal: Cancer Res
Title: O6-alkylguanine-DNA alkyltransferase attenuates triazene-induced cytotoxicity and tumor cell immunogenicity in murine L1210 leukemia.
Volume: 55
Issue: 24
Pages: 6231-6
Publication
First Author: Iwakuma T
Year: 1996
Journal: DNA Cell Biol
Title: Organization and expression of the mouse gene for DNA repair methyltransferase.
Volume: 15
Issue: 10
Pages: 863-72
Publication
First Author: Loktionova NA
Year: 2002
Journal: Biochem Pharmacol
Title: Interaction of mammalian O(6)-alkylguanine-DNA alkyltransferases with O(6)-benzylguanine.
Volume: 63
Issue: 8
Pages: 1431-42
Publication
First Author: Meira LB
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Aag-initiated base excision repair drives alkylation-induced retinal degeneration in mice.
Volume: 106
Issue: 3
Pages: 888-93
Publication
First Author: Burns N
Year: 2007
Journal: Toxicol Sci
Title: The effect of 3-methyladenine DNA glycosylase-mediated DNA repair on the induction of toxicity and diabetes by the beta-cell toxicant streptozotocin.
Volume: 95
Issue: 2
Pages: 391-400
Publication
First Author: Klapacz J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo.
Volume: 106
Issue: 2
Pages: 576-81
Publication
First Author: Guimarães MJ
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Identification of a novel selD homolog from eukaryotes, bacteria, and archaea: is there an autoregulatory mechanism in selenocysteine metabolism?
Volume: 93
Issue: 26
Pages: 15086-91
Publication
First Author: Koch A
Year: 1997
Journal: Mamm Genome
Title: cDNA cloning and chromosomal mapping of mouse fast skeletal muscle troponin T.
Volume: 8
Issue: 5
Pages: 346-8
Publication
First Author: Quach TT
Year: 2000
Journal: Gene
Title: Collapsin response mediator protein-3/unc-33-like protein-4 gene: organization, chromosomal mapping and expression in the developing mouse brain.
Volume: 242
Issue: 1-2
Pages: 175-82
Publication
First Author: Guillemot F
Year: 1995
Journal: Nat Genet
Title: Genomic imprinting of Mash2, a mouse gene required for trophoblast development.
Volume: 9
Issue: 3
Pages: 235-42
Publication
First Author: Avraham KB
Year: 1994
Journal: Genomics
Title: Mapping of murine fibroblast growth factor receptors refines regions of homology between mouse and human chromosomes.
Volume: 21
Issue: 3
Pages: 656-8
Publication
First Author: Shworak NW
Year: 1999
Journal: J Biol Chem
Title: Multiple isoforms of heparan sulfate D-glucosaminyl 3-O-sulfotransferase. Isolation, characterization, and expression of human cdnas and identification of distinct genomic loci.
Volume: 274
Issue: 8
Pages: 5170-84
Publication
First Author: Avraham KB
Year: 1995
Journal: Genomics
Title: Murine chromosomal location of eight members of the hepatocyte nuclear factor 3/fork head winged helix family of transcription factors.
Volume: 25
Issue: 2
Pages: 388-93
Publication
First Author: Sierra DA
Year: 2002
Journal: Genomics
Title: Evolution of the regulators of G-protein signaling multigene family in mouse and human.
Volume: 79
Issue: 2
Pages: 177-85
Publication
First Author: Lewandowski JP
Year: 2015
Journal: Dev Biol
Title: Spatiotemporal regulation of GLI target genes in the mammalian limb bud.
Volume: 406
Issue: 1
Pages: 92-103
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Araki K
Year: 1999
Journal: Cell Mol Biol (Noisy-le-grand)
Title: Exchangeable gene trap using the Cre/mutated lox system.
Volume: 45
Issue: 5
Pages: 737-50
Publication
First Author: Taniwaki T
Year: 2005
Journal: Dev Growth Differ
Title: Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette.
Volume: 47
Issue: 3
Pages: 163-72
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Becker K
Year: 2003
Journal: Carcinogenesis
Title: DNA repair protein MGMT protects against N-methyl-N-nitrosourea-induced conversion of benign into malignant tumors.
Volume: 24
Issue: 3
Pages: 541-6
Publication
First Author: Winter JM
Year: 2014
Journal: J Nutrigenet Nutrigenomics
Title: Role of Red Meat and Resistant Starch in Promutagenic Adduct Formation, MGMT Repair, Thymic Lymphoma and Intestinal Tumourigenesis in Msh2 -Deficient Mice.
Volume: 7
Issue: 4-6
Pages: 299-313
Publication
First Author: Becker K
Year: 1996
Journal: Cancer Res
Title: Targeted expression of human O(6)-methylguanine-DNA methyltransferase (MGMT) in transgenic mice protects against tumor initiation in two-stage skin carcinogenesis.
Volume: 56
Issue: 14
Pages: 3244-9
Publication
First Author: Qin X
Year: 2000
Journal: Jpn J Cancer Res
Title: Protection against malignant progression of spontaneously developing liver tumors in transgenic mice expressing O(6)-methylguanine-DNA methyltransferase.
Volume: 91
Issue: 11
Pages: 1085-9
Publication
First Author: Mukai T
Year: 2002
Journal: Oncogene
Title: Gene silencing in phenomena related to DNA repair.
Volume: 21
Issue: 58
Pages: 9033-42
Publication
First Author: Vengoji R
Year: 2021
Journal: J Exp Clin Cancer Res
Title: Differential gene expression-based connectivity mapping identified novel drug candidate and improved Temozolomide efficacy for Glioblastoma.
Volume: 40
Issue: 1
Pages: 335
Publication
First Author: Rao S
Year: 2019
Journal: PLoS One
Title: RPL22L1 induction in colorectal cancer is associated with poor prognosis and 5-FU resistance.
Volume: 14
Issue: 10
Pages: e0222392
Publication
First Author: Borgenvik A
Year: 2022
Journal: Cancer Res
Title: Dormant SOX9-Positive Cells Facilitate MYC-Driven Recurrence of Medulloblastoma.
Volume: 82
Issue: 24
Pages: 4586-4603
Publication
First Author: Chen T
Year: 1998
Journal: Teratog Carcinog Mutagen
Title: Possible rare involvement of O6-methylguanine formation as a significant mutational factor in mouse urinary bladder carcinogenesis models.
Volume: 18
Issue: 3
Pages: 101-10
Publication
First Author: Allay E
Year: 1999
Journal: Oncogene
Title: Mice over-expressing human O6 alkylguanine-DNA alkyltransferase selectively reduce O6 methylguanine mediated carcinogenic mutations to threshold levels after N-methyl-N-nitrosourea.
Volume: 18
Issue: 25
Pages: 3783-7
Publication
First Author: Shirakami Y
Year: 2012
Journal: Carcinogenesis
Title: Diethylnitrosamine-induced hepatocarcinogenesis is suppressed in lecithin:retinol acyltransferase-deficient mice primarily through retinoid actions immediately after carcinogen administration.
Volume: 33
Issue: 2
Pages: 268-74
Publication
First Author: Blough MD
Year: 2007
Journal: Cancer Res
Title: O6-methylguanine-DNA methyltransferase regulation by p53 in astrocytic cells.
Volume: 67
Issue: 2
Pages: 580-4
Publication
First Author: Nakatsuru Y
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: O6-methylguanine-DNA methyltransferase protects against nitrosamine-induced hepatocarcinogenesis.
Volume: 90
Issue: 14
Pages: 6468-72
Publication
First Author: Anisimov VN
Year: 2001
Journal: Mech Ageing Dev
Title: Mutant and genetically modified mice as models for studying the relationship between aging and carcinogenesis.
Volume: 122
Issue: 12
Pages: 1221-55