|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 101 to 200 out of 1741 for Nkx2-5

0.061s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Publication
First Author: Ding B
Year: 2006
Journal: J Biol Chem
Title: p204 protein overcomes the inhibition of the differentiation of P19 murine embryonal carcinoma cells to beating cardiac myocytes by Id proteins.
Volume: 281
Issue: 21
Pages: 14893-906
Publication
First Author: Biben C
Year: 2002
Journal: Int J Dev Biol
Title: NK-2 class homeobox genes and pharyngeal/oral patterning: Nkx2-3 is required for salivary gland and tooth morphogenesis.
Volume: 46
Issue: 4
Pages: 415-22
Publication
First Author: Lee Y
Year: 1998
Journal: Mol Cell Biol
Title: The cardiac tissue-restricted homeobox protein Csx/Nkx2.5 physically associates with the zinc finger protein GATA4 and cooperatively activates atrial natriuretic factor gene expression.
Volume: 18
Issue: 6
Pages: 3120-9
Publication
First Author: Kim TG
Year: 2004
Journal: Mol Cell Biol
Title: Jumonji represses atrial natriuretic factor gene expression by inhibiting transcriptional activities of cardiac transcription factors.
Volume: 24
Issue: 23
Pages: 10151-60
Publication
First Author: Farin HF
Year: 2007
Journal: J Biol Chem
Title: Transcriptional repression by the T-box proteins Tbx18 and Tbx15 depends on Groucho corepressors.
Volume: 282
Issue: 35
Pages: 25748-59
Publication
First Author: Lee KH
Year: 2004
Journal: Development
Title: SMAD-mediated modulation of YY1 activity regulates the BMP response and cardiac-specific expression of a GATA4/5/6-dependent chick Nkx2.5 enhancer.
Volume: 131
Issue: 19
Pages: 4709-23
Publication
First Author: Ding B
Year: 2006
Journal: J Biol Chem
Title: p204 is required for the differentiation of P19 murine embryonal carcinoma cells to beating cardiac myocytes: its expression is activated by the cardiac Gata4, Nkx2.5, and Tbx5 proteins.
Volume: 281
Issue: 21
Pages: 14882-92
Publication
First Author: Komuro I
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: Csx: a murine homeobox-containing gene specifically expressed in the developing heart.
Volume: 90
Issue: 17
Pages: 8145-9
Publication
First Author: Baardman ME
Year: 2016
Journal: Dis Model Mech
Title: Common arterial trunk and ventricular non-compaction in Lrp2 knockout mice indicate a crucial role of LRP2 in cardiac development.
Volume: 9
Issue: 4
Pages: 413-25
Publication
First Author: Medioni C
Year: 2010
Journal: Dev Dyn
Title: Expression of Slit and Robo genes in the developing mouse heart.
Volume: 239
Issue: 12
Pages: 3303-11
Publication
First Author: Tanaka M
Year: 1999
Journal: Development
Title: The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development.
Volume: 126
Issue: 6
Pages: 1269-80
Publication
First Author: Gittenberger-de Groot AC
Year: 2020
Journal: PLoS One
Title: Pulmonary ductal coarctation and left pulmonary artery interruption; pathology and role of neural crest and second heart field during development.
Volume: 15
Issue: 5
Pages: e0228478
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Publication      
First Author: Schramm C
Year: 2012
Journal: MGI Direct Data Submission
Title: Information about alleles developed by members of the NHLBI Cardiovascular Development Consortium (CvDC), Bench to Bassinet Program
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Klaus A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis.
Volume: 104
Issue: 47
Pages: 18531-6
Publication
First Author: Ieda M
Year: 2009
Journal: Dev Cell
Title: Cardiac fibroblasts regulate myocardial proliferation through beta1 integrin signaling.
Volume: 16
Issue: 2
Pages: 233-44
Publication
First Author: Xu H
Year: 2004
Journal: Development
Title: Tbx1 has a dual role in the morphogenesis of the cardiac outflow tract.
Volume: 131
Issue: 13
Pages: 3217-27
Publication
First Author: Cheng Z
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Focal adhesion kinase regulates smooth muscle cell recruitment to the developing vasculature.
Volume: 31
Issue: 10
Pages: 2193-202
Publication
First Author: Watanabe Y
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Fibroblast growth factor 10 gene regulation in the second heart field by Tbx1, Nkx2-5, and Islet1 reveals a genetic switch for down-regulation in the myocardium.
Volume: 109
Issue: 45
Pages: 18273-80
Publication
First Author: Kokkinopoulos I
Year: 2015
Journal: PLoS One
Title: Single-Cell Expression Profiling Reveals a Dynamic State of Cardiac Precursor Cells in the Early Mouse Embryo.
Volume: 10
Issue: 10
Pages: e0140831
Publication
First Author: Hamline MY
Year: 2020
Journal: Dev Biol
Title: OFCD syndrome and extraembryonic defects are revealed by conditional mutation of the Polycomb-group repressive complex 1.1 (PRC1.1) gene BCOR.
Volume: 468
Issue: 1-2
Pages: 110-132
Publication  
First Author: Moreau JLM
Year: 2019
Journal: Development
Title: Gene-environment interaction impacts on heart development and embryo survival.
Volume: 146
Issue: 4
Publication
First Author: Ryckebusch L
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Retinoic acid deficiency alters second heart field formation.
Volume: 105
Issue: 8
Pages: 2913-8
Publication
First Author: Gladman JT
Year: 2015
Journal: Hum Mol Genet
Title: NKX2-5, a modifier of skeletal muscle pathology due to RNA toxicity.
Volume: 24
Issue: 1
Pages: 251-64
Publication
First Author: Huang J
Year: 2012
Journal: J Clin Invest
Title: Myocardin regulates BMP10 expression and is required for heart development.
Volume: 122
Issue: 10
Pages: 3678-91
Publication
First Author: Zhou B
Year: 2008
Journal: Nature
Title: Epicardial progenitors contribute to the cardiomyocyte lineage in the developing heart.
Volume: 454
Issue: 7200
Pages: 109-13
Publication
First Author: Serpooshan V
Year: 2017
Journal: Sci Rep
Title: Nkx2.5+ Cardiomyoblasts Contribute to Cardiomyogenesis in the Neonatal Heart.
Volume: 7
Issue: 1
Pages: 12590
Publication
First Author: Firulli BA
Year: 2020
Journal: Cardiovasc Res
Title: HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure.
Volume: 116
Issue: 3
Pages: 605-618
Publication
First Author: Misra C
Year: 2012
Journal: PLoS Genet
Title: Congenital heart disease-causing Gata4 mutation displays functional deficits in vivo.
Volume: 8
Issue: 5
Pages: e1002690
Publication
First Author: Niu Z
Year: 2005
Journal: J Biol Chem
Title: Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.
Volume: 280
Issue: 37
Pages: 32531-8
Publication
First Author: Lewandowski SL
Year: 2014
Journal: Hum Mol Genet
Title: Histone deacetylase 3 modulates Tbx5 activity to regulate early cardiogenesis.
Volume: 23
Issue: 14
Pages: 3801-9
Publication
First Author: Huang W
Year: 2018
Journal: Exp Cell Res
Title: Heterogeneity of adult masseter muscle satellite cells with cardiomyocyte differentiation potential.
Volume: 371
Issue: 1
Pages: 20-30
Publication
First Author: Gifford CA
Year: 2019
Journal: Science
Title: Oligogenic inheritance of a human heart disease involving a genetic modifier.
Volume: 364
Issue: 6443
Pages: 865-870
Publication
First Author: Liu Y
Year: 2014
Journal: Hum Mol Genet
Title: CHD7 interacts with BMP R-SMADs to epigenetically regulate cardiogenesis in mice.
Volume: 23
Issue: 8
Pages: 2145-56
Publication
First Author: Thattaliyath BD
Year: 2002
Journal: J Mol Cell Cardiol
Title: The basic-helix-loop-helix transcription factor HAND2 directly regulates transcription of the atrial naturetic peptide gene.
Volume: 34
Issue: 10
Pages: 1335-44
Publication
First Author: Oyama K
Year: 2018
Journal: Epigenetics Chromatin
Title: Deletion of HP1γ in cardiac myocytes affects H4K20me3 levels but does not impact cardiac growth.
Volume: 11
Issue: 1
Pages: 18
Publication
First Author: Mommersteeg MT
Year: 2010
Journal: Cardiovasc Res
Title: The sinus venosus progenitors separate and diversify from the first and second heart fields early in development.
Volume: 87
Issue: 1
Pages: 92-101
Publication  
First Author: Kim KH
Year: 2016
Journal: Sci Rep
Title: Irx3 is required for postnatal maturation of the mouse ventricular conduction system.
Volume: 6
Pages: 19197
Publication  
First Author: Takeuchi JK
Year: 2011
Journal: Nat Commun
Title: Chromatin remodelling complex dosage modulates transcription factor function in heart development.
Volume: 2
Pages: 187
Publication
First Author: Ye W
Year: 2015
Journal: Development
Title: A common Shox2-Nkx2-5 antagonistic mechanism primes the pacemaker cell fate in the pulmonary vein myocardium and sinoatrial node.
Volume: 142
Issue: 14
Pages: 2521-32
Publication
First Author: Liu H
Year: 2011
Journal: J Biol Chem
Title: Functional redundancy between human SHOX and mouse Shox2 genes in the regulation of sinoatrial node formation and pacemaking function.
Volume: 286
Issue: 19
Pages: 17029-38
Publication
First Author: Blaschke RJ
Year: 2007
Journal: Circulation
Title: Targeted mutation reveals essential functions of the homeodomain transcription factor Shox2 in sinoatrial and pacemaking development.
Volume: 115
Issue: 14
Pages: 1830-8
Publication
First Author: Huang X
Year: 2022
Journal: J Biol Chem
Title: The G4 resolvase RHAU regulates ventricular trabeculation and compaction through transcriptional and post-transcriptional mechanisms.
Volume: 298
Issue: 1
Pages: 101449
Publication
First Author: Menendez-Montes I
Year: 2021
Journal: iScience
Title: Activation of amino acid metabolic program in cardiac HIF1-alpha-deficient mice.
Volume: 24
Issue: 2
Pages: 102124
Publication
First Author: Espinoza-Lewis RA
Year: 2009
Journal: Dev Biol
Title: Shox2 is essential for the differentiation of cardiac pacemaker cells by repressing Nkx2-5.
Volume: 327
Issue: 2
Pages: 376-85
Publication
First Author: Douglas YL
Year: 2009
Journal: Pediatr Res
Title: Pulmonary vein, dorsal atrial wall and atrial septum abnormalities in podoplanin knockout mice with disturbed posterior heart field contribution.
Volume: 65
Issue: 1
Pages: 27-32
Publication  
First Author: Conti MA
Year: 2015
Journal: Sci Rep
Title: Conditional deletion of nonmuscle myosin II-A in mouse tongue epithelium results in squamous cell carcinoma.
Volume: 5
Pages: 14068
Publication
First Author: Doll CF
Year: 2021
Journal: Sci Rep
Title: Gestational intermittent hyperoxia rescues murine genetic congenital heart disease in part.
Volume: 11
Issue: 1
Pages: 6608
Publication  
First Author: Moumne O
Year: 2018
Journal: Front Cardiovasc Med
Title: Mechanism Sharing Between Genetic and Gestational Hypoxia-Induced Cardiac Anomalies.
Volume: 5
Pages: 100
Publication
First Author: Sabirzhanova I
Year: 2009
Journal: Dev Growth Differ
Title: Activation of Tolloid-like 1 gene expression by the cardiac specific homeobox gene Nkx2-5.
Volume: 51
Issue: 4
Pages: 403-10
Publication
First Author: Dentice M
Year: 2006
Journal: J Clin Endocrinol Metab
Title: Missense mutation in the transcription factor NKX2-5: a novel molecular event in the pathogenesis of thyroid dysgenesis.
Volume: 91
Issue: 4
Pages: 1428-33
Publication
First Author: Luna-Zurita L
Year: 2016
Journal: Cell
Title: Complex Interdependence Regulates Heterotypic Transcription Factor Distribution and Coordinates Cardiogenesis.
Volume: 164
Issue: 5
Pages: 999-1014
Publication
First Author: DeLaughter DM
Year: 2016
Journal: Dev Cell
Title: Single-Cell Resolution of Temporal Gene Expression during Heart Development.
Volume: 39
Issue: 4
Pages: 480-490
Publication
First Author: Winston JB
Year: 2010
Journal: Circulation
Title: Heterogeneity of genetic modifiers ensures normal cardiac development.
Volume: 121
Issue: 11
Pages: 1313-21
Publication
First Author: Qian L
Year: 2011
Journal: J Cell Biol
Title: Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species.
Volume: 193
Issue: 7
Pages: 1181-96
Publication
First Author: Schulkey CE
Year: 2015
Journal: Nature
Title: The maternal-age-associated risk of congenital heart disease is modifiable.
Volume: 520
Issue: 7546
Pages: 230-3
Publication
First Author: Biben C
Year: 2000
Journal: Circ Res
Title: Cardiac septal and valvular dysmorphogenesis in mice heterozygous for mutations in the homeobox gene Nkx2-5.
Volume: 87
Issue: 10
Pages: 888-95
Publication
First Author: Prall OW
Year: 2007
Journal: Cell
Title: An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation.
Volume: 128
Issue: 5
Pages: 947-59
Publication
First Author: Mommersteeg MT
Year: 2007
Journal: Circ Res
Title: Molecular pathway for the localized formation of the sinoatrial node.
Volume: 100
Issue: 3
Pages: 354-62
Publication
First Author: Ivanova A
Year: 2005
Journal: Genesis
Title: In vivo genetic ablation by Cre-mediated expression of diphtheria toxin fragment A.
Volume: 43
Issue: 3
Pages: 129-35
Publication  
First Author: Sugioka S
Year: 2022
Journal: Biochem Biophys Res Commun
Title: Effects of constitutively active IKKβ on cardiac development.
Volume: 614
Pages: 169-174
Publication
First Author: Moses KA
Year: 2001
Journal: Genesis
Title: Embryonic expression of an Nkx2-5/Cre gene using ROSA26 reporter mice.
Volume: 31
Issue: 4
Pages: 176-80
Publication
First Author: Zhou B
Year: 2008
Journal: Biochem Biophys Res Commun
Title: Nkx2-5- and Isl1-expressing cardiac progenitors contribute to proepicardium.
Volume: 375
Issue: 3
Pages: 450-3
Publication  
First Author: Franco A
Year: 2018
Journal: J Mol Cell Cardiol
Title: G-protein receptor kinases 2, 5 and 6 redundantly modulate Smoothened-GATA transcriptional crosstalk in fetal mouse hearts.
Volume: 121
Pages: 60-68
Publication
First Author: Gregoire S
Year: 2017
Journal: Stem Cells
Title: YY1 Expression Is Sufficient for the Maintenance of Cardiac Progenitor Cell State.
Volume: 35
Issue: 8
Pages: 1913-1923
Publication
First Author: Kim EY
Year: 2012
Journal: J Mol Cell Cardiol
Title: Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction.
Volume: 52
Issue: 3
Pages: 638-49
Publication
First Author: Rasmussen TL
Year: 2015
Journal: PLoS One
Title: Smyd1 facilitates heart development by antagonizing oxidative and ER stress responses.
Volume: 10
Issue: 3
Pages: e0121765
Publication  
First Author: Ranjbarvaziri S
Year: 2017
Journal: Genesis
Title: Generation of Nkx2-5/CreER transgenic mice for inducible Cre expression in developing hearts.
Volume: 55
Issue: 8
Publication
First Author: Stanley EG
Year: 2002
Journal: Int J Dev Biol
Title: Efficient Cre-mediated deletion in cardiac progenitor cells conferred by a 3'UTR-ires-Cre allele of the homeobox gene Nkx2-5.
Volume: 46
Issue: 4
Pages: 431-9
Publication
First Author: Xiong H
Year: 2019
Journal: Circ Res
Title: Single-Cell Transcriptomics Reveals Chemotaxis-Mediated Intraorgan Crosstalk During Cardiogenesis.
Volume: 125
Issue: 4
Pages: 398-410
Publication
First Author: Zhang F
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: Divergent cell cycle kinetics of midgestation ventricular cells entail a higher engraftment efficiency after cell transplantation.
Volume: 308
Issue: 3
Pages: C220-8
Publication
First Author: Lyons I
Year: 1995
Journal: Genes Dev
Title: Myogenic and morphogenetic defects in the heart tubes of murine embryos lacking the homeo box gene Nkx2-5.
Volume: 9
Issue: 13
Pages: 1654-66
Publication
First Author: Ross RS
Year: 1996
Journal: Development
Title: An HF-1a/HF-1b/MEF-2 combinatorial element confers cardiac ventricular specificity and established an anterior-posterior gradient of expression.
Volume: 122
Issue: 6
Pages: 1799-809
Publication
First Author: Zhang S
Year: 2019
Journal: Cardiovasc Res
Title: WD40 repeat and FYVE domain containing 3 is essential for cardiac development.
Volume: 115
Issue: 8
Pages: 1320-1331
Publication
First Author: Cordes KR
Year: 2009
Journal: Nature
Title: miR-145 and miR-143 regulate smooth muscle cell fate and plasticity.
Volume: 460
Issue: 7256
Pages: 705-10
Publication
First Author: Burn SF
Year: 2008
Journal: Dev Biol
Title: The dynamics of spleen morphogenesis.
Volume: 318
Issue: 2
Pages: 303-11
Publication
First Author: Yuan X
Year: 2017
Journal: J Clin Invest
Title: Disruption of spatiotemporal hypoxic signaling causes congenital heart disease in mice.
Volume: 127
Issue: 6
Pages: 2235-2248
Publication  
First Author: Foley TE
Year: 2019
Journal: Development
Title: Role of Cdx factors in early mesodermal fate decisions.
Volume: 146
Issue: 7
Publication
First Author: Scherptong RW
Year: 2012
Journal: Dev Dyn
Title: Morphogenesis of outflow tract rotation during cardiac development: the pulmonary push concept.
Volume: 241
Issue: 9
Pages: 1413-22
Publication  
First Author: Leung C
Year: 2021
Journal: J Cardiovasc Dev Dis
Title: Myocardium-Specific Deletion of Rac1 Causes Ventricular Noncompaction and Outflow Tract Defects.
Volume: 8
Issue: 3
Publication
First Author: Shawer H
Year: 2020
Journal: PLoS One
Title: A missense mutation of ErbB2 produces a novel mouse model of stillbirth associated with a cardiac abnormality but lacking abnormalities of placental structure.
Volume: 15
Issue: 6
Pages: e0233007
Publication
First Author: Pu WT
Year: 2004
Journal: Dev Biol
Title: GATA4 is a dosage-sensitive regulator of cardiac morphogenesis.
Volume: 275
Issue: 1
Pages: 235-44
Publication
First Author: Bruneau BG
Year: 2001
Journal: Cell
Title: A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease.
Volume: 106
Issue: 6
Pages: 709-21
Publication
First Author: von Both I
Year: 2004
Journal: Dev Cell
Title: Foxh1 is essential for development of the anterior heart field.
Volume: 7
Issue: 3
Pages: 331-45
Publication
First Author: Koshiba-Takeuchi K
Year: 2009
Journal: Nature
Title: Reptilian heart development and the molecular basis of cardiac chamber evolution.
Volume: 461
Issue: 7260
Pages: 95-8
Publication
First Author: Gregoire S
Year: 2013
Journal: Circ Res
Title: Essential and unexpected role of Yin Yang 1 to promote mesodermal cardiac differentiation.
Volume: 112
Issue: 6
Pages: 900-10
Publication
First Author: Shirai M
Year: 2002
Journal: J Clin Invest
Title: The Polycomb-group gene Rae28 sustains Nkx2.5/Csx expression and is essential for cardiac morphogenesis.
Volume: 110
Issue: 2
Pages: 177-84
Publication
First Author: Yuasa S
Year: 2010
Journal: Circ Res
Title: Zac1 is an essential transcription factor for cardiac morphogenesis.
Volume: 106
Issue: 6
Pages: 1083-91
Publication
First Author: Pabst O
Year: 2000
Journal: Dev Genes Evol
Title: NKX2 gene expression in neuroectoderm but not in mesendodermally derived structures depends on sonic hedgehog in mouse embryos.
Volume: 210
Issue: 1
Pages: 47-50
Publication
First Author: Takeuchi JK
Year: 2005
Journal: Development
Title: Tbx20 dose-dependently regulates transcription factor networks required for mouse heart and motoneuron development.
Volume: 132
Issue: 10
Pages: 2463-74
Publication
First Author: Costa MW
Year: 2011
Journal: PLoS One
Title: Complex SUMO-1 regulation of cardiac transcription factor Nkx2-5.
Volume: 6
Issue: 9
Pages: e24812
Publication
First Author: Boogerd KJ
Year: 2008
Journal: Cardiovasc Res
Title: Msx1 and Msx2 are functional interacting partners of T-box factors in the regulation of Connexin43.
Volume: 78
Issue: 3
Pages: 485-93
Publication
First Author: Riazi AM
Year: 2005
Journal: J Biol Chem
Title: CSX/Nkx2.5 modulates differentiation of skeletal myoblasts and promotes differentiation into neuronal cells in vitro.
Volume: 280
Issue: 11
Pages: 10716-20
Publication
First Author: Hiroi Y
Year: 2001
Journal: Nat Genet
Title: Tbx5 associates with Nkx2-5 and synergistically promotes cardiomyocyte differentiation.
Volume: 28
Issue: 3
Pages: 276-80
Publication
First Author: Kasahara H
Year: 2001
Journal: J Clin Invest
Title: Progressive atrioventricular conduction defects and heart failure in mice expressing a mutant Csx/Nkx2.5 homeoprotein.
Volume: 108
Issue: 2
Pages: 189-201
Publication
First Author: Parmar H
Year: 2001
Journal: Genesis
Title: An enhancer sequence directs LacZ expression to developing pharyngeal endoderm in transgenic mice.
Volume: 31
Issue: 2
Pages: 57-63
Publication
First Author: Sparrow DB
Year: 2000
Journal: Dev Biol
Title: Regulation of the tinman homologues in Xenopus embryos.
Volume: 227
Issue: 1
Pages: 65-79
Publication
First Author: Charng MJ
Year: 1998
Journal: Dev Biol
Title: A constitutive mutation of ALK5 disrupts cardiac looping and morphogenesis in mice.
Volume: 199
Issue: 1
Pages: 72-9
Publication
First Author: Reecy JM
Year: 1999
Journal: Development
Title: Identification of upstream regulatory regions in the heart-expressed homeobox gene Nkx2-5.
Volume: 126
Issue: 4
Pages: 839-49