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Search results 2501 to 2565 out of 2565 for Eomes

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Type Details Score
Allele
Eomes<em2Mhos> | MGI:7282251
Name: eomesodermin; endonuclease-mediated mutation 2, Mikio Hoshino
Allele Type: Endonuclease-mediated
Attribute String: Reporter
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Allele
Eomes<tm3(flpo)Zjh> | MGI:7523052
Name: eomesodermin; targeted mutation 3, Z Josh Huang
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Tg(Eomes-lacZ)1Whk | MGI:3774152
Name: transgene insertion 1, William H Klein
Allele Type: Transgenic
Attribute String: Reporter
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Allele
Eomes<em1Smoc> | MGI:7289514
Name: eomesodermin; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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HT Experiment
E-GEOD-43387 | The protomap is propagated to cortical plate neurons through an Eomes-dependent intermediate map
Series Id: GSE43387
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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HT Experiment
GSE151824 | Spatiotemporal sequence of mesoderm and endoderm lineage segregation during mouse gastrulation
 
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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GXD Expression
GXD Expression
Probe: MGI:7621464
Assay Type: Immunohistochemistry
Annotation Date: 2024-04-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754420
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:7621561
Age: embryonic day 12.5
Image: 6C ESCO2cKO
Note: In the conditional mutant, expression was lower in the lateral area of the cortex. Co-expression with Casp3 and Eomes indicated there was increased apoptosis in cells in transition stage between radial glia progenitor cells/intermediate progenitor cells (Eomes+/Pax6+) and in radial glial progenitor cells (Pax6+).
Specimen Label: 6C ESCO2cKO
Detected: true
Specimen Num: 5
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Allele
Tg(Eomes-tdTomato)TP20Gsat | MGI:5435488
Name: transgene insertion TP20, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:6475201 | C57BL/6-Eomes<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(Eomes-cre)SO41Gsat | MGI:5311720
Name: transgene insertion SO41, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Recombinase
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HT Experiment
GSE54291 | Differential requirement for Nfil3 during NK cell development
Series Id: E-GEOD-54291
Experiment Type: RNA-Seq
Study Type: Baseline
Source: GEO
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Strain
MGI:5435809 | STOCK Tg(Eomes-tdTomato)TP20Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Allele
Eomes<tm4.1(icre)Rob> | MGI:6718928
Name: eomesodermin; targeted mutation 3.1, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Eomes<tm3.1(cre)Rob> | MGI:5296755
Name: eomesodermin; targeted mutation 3.1, Elizabeth J Robertson
Allele Type: Targeted
Attribute String: Recombinase
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Allele
Eomes<tm1.1(cre/ERT2)Zjh> | MGI:6720841
Name: eomesodermin; targeted mutation 1.1, Z Josh Huang
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Allele
Eomes<tm2.1(flpo/ERT2)Zjh> | MGI:6720888
Name: eomesodermin; targeted mutation 2.1, Z Josh Huang
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Allele
Eomes<tm1.1(cre/ERT2)Sjar> | MGI:5499762
Name: eomesodermin; targeted mutation 1.1, Sebastian J Arnold
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Strain
MGI:5312989 | STOCK Tg(Eomes-cre)SO41Gsat/Mmucd
Attribute String: transgenic, mutant stock
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Strain
MGI:6720854 | B6;129S4-Eomes<tm1.1(cre/ERT2)Zjh>/J
Attribute String: mutant stock, targeted mutation
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Genotype
Genotype
Symbol: Eomes/Eomes<+>
Background: involves: 129S/SvEv
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eomes/Eomes
Background: involves: 129S/SvEv
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eomes/Eomes<+>
Background: Not Specified
Zygosity: ht
Has Mutant Allele: true
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Publication
19471017 | J:150734
First Author: Hinrichs CS
Year: 2009
Journal: Blood
Title: Type 17 CD8+ T cells display enhanced antitumor immunity.
Volume: 114
Issue: 3
Pages: 596-9
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Publication
26804903 | J:315422
First Author: Zhang L
Year: 2016
Journal: Cell Rep
Title: Mammalian Target of Rapamycin Complex 2 Controls CD8 T Cell Memory Differentiation in a Foxo1-Dependent Manner.
Volume: 14
Issue: 5
Pages: 1206-1217
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Publication
17114419 | J:140606
First Author: Takemoto N
Year: 2006
Journal: J Immunol
Title: Cutting Edge: IL-12 inversely regulates T-bet and eomesodermin expression during pathogen-induced CD8+ T cell differentiation.
Volume: 177
Issue: 11
Pages: 7515-9
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Publication
21820330 | J:175847
First Author: Steiner DF
Year: 2011
Journal: Immunity
Title: MicroRNA-29 regulates T-box transcription factors and interferon-γ production in helper T cells.
Volume: 35
Issue: 2
Pages: 169-81
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Publication
27601261 | J:242101
 
First Author: Yang M
Year: 2016
Journal: Nat Commun
Title: NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activation.
Volume: 7
Pages: 12730
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Publication
20096607 | J:157692
First Author: Pipkin ME
Year: 2010
Journal: Immunity
Title: Interleukin-2 and inflammation induce distinct transcriptional programs that promote the differentiation of effector cytolytic T cells.
Volume: 32
Issue: 1
Pages: 79-90
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Publication
29625896 | J:272657
First Author: Li J
Year: 2018
Journal: Immunity
Title: Co-inhibitory Molecule B7 Superfamily Member 1 Expressed by Tumor-Infiltrating Myeloid Cells Induces Dysfunction of Anti-tumor CD8+ T Cells.
Volume: 48
Issue: 4
Pages: 773-786.e5
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Publication
23933258 | J:201892
First Author: Knudson KM
Year: 2013
Journal: Cell Rep
Title: Low-affinity T cells are programmed to maintain normal primary responses but are impaired in their recall to low-affinity ligands.
Volume: 4
Issue: 3
Pages: 554-65
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Publication
20727791 | J:163912
First Author: Zhou X
Year: 2010
Journal: Immunity
Title: Differentiation and persistence of memory CD8(+) T cells depend on T cell factor 1.
Volume: 33
Issue: 2
Pages: 229-40
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Publication
35573205 | J:328754
First Author: Takahashi F
Year: 2022
Journal: iScience
Title: Immune-mediated neurodegenerative trait provoked by multimodal derepression of long-interspersed nuclear element-1.
Volume: 25
Issue: 5
Pages: 104278
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Publication
36964178 | J:336049
First Author: Read KA
Year: 2023
Journal: Nat Commun
Title: Aiolos represses CD4(+) T cell cytotoxic programming via reciprocal regulation of T(FH) transcription factors and IL-2 sensitivity.
Volume: 14
Issue: 1
Pages: 1652
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Publication
19139168 | J:144022
First Author: Cruz-Guilloty F
Year: 2009
Journal: J Exp Med
Title: Runx3 and T-box proteins cooperate to establish the transcriptional program of effector CTLs.
Volume: 206
Issue: 1
Pages: 51-9
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Publication
19265115 | J:145933
First Author: Cho OH
Year: 2009
Journal: J Immunol
Title: Notch regulates cytolytic effector function in CD8+ T cells.
Volume: 182
Issue: 6
Pages: 3380-9
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Publication
28276053 | J:249851
First Author: Gabrielli S
Year: 2017
Journal: Eur J Immunol
Title: Murine thymic NK cells are distinct from ILC1s and have unique transcription factor requirements.
Volume: 47
Issue: 5
Pages: 800-805
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Publication
31606264 | J:282315
First Author: Chen Z
Year: 2019
Journal: Immunity
Title: TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision.
Volume: 51
Issue: 5
Pages: 840-855.e5
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Genotype
Genotype
Symbol: Eomes/Eomes<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S4/SvJaeSor
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Eomes/Eomes<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCrl
Zygosity: cn
Has Mutant Allele: true
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Publication
28758191 | J:248992
First Author: Liu Z
Year: 2017
Journal: Immunology
Title: Interleukin-27 signalling induces stem cell antigen-1 expression in T lymphocytes in vivo.
Volume: 152
Issue: 4
Pages: 638-647
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Publication
31466995 | J:295221
First Author: Shi LZ
Year: 2019
Journal: Cancer Immunol Res
Title: Blockade of CTLA-4 and PD-1 Enhances Adoptive T-cell Therapy Efficacy in an ICOS-Mediated Manner.
Volume: 7
Issue: 11
Pages: 1803-1812
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Publication
26416483 | J:227544
First Author: Wissink EM
Year: 2015
Journal: Genetics
Title: MicroRNAs and Their Targets Are Differentially Regulated in Adult and Neonatal Mouse CD8+ T Cells.
Volume: 201
Issue: 3
Pages: 1017-30
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Publication
24058178 | J:206252
First Author: Sabet-Baktach M
Year: 2013
Journal: J Immunol
Title: Double deficiency for RORγt and T-bet drives Th2-mediated allograft rejection in mice.
Volume: 191
Issue: 8
Pages: 4440-6
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Publication
28827827 | J:245975
First Author: Shin HM
Year: 2017
Journal: PLoS Pathog
Title: Transient expression of ZBTB32 in anti-viral CD8+ T cells limits the magnitude of the effector response and the generation of memory.
Volume: 13
Issue: 8
Pages: e1006544
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Publication
25422283 | J:230917
First Author: Hirose S
Year: 2015
Journal: Int Immunol
Title: Bcl11b prevents the intrathymic development of innate CD8 T cells in a cell intrinsic manner.
Volume: 27
Issue: 4
Pages: 205-15
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Publication
26749286 | J:246186
First Author: Suzuki J
Year: 2016
Journal: Immunology
Title: Gfi1, a transcriptional repressor, inhibits the induction of the T helper type 1 programme in activated CD4 T cells.
Volume: 147
Issue: 4
Pages: 476-87
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Publication
30319610 | J:295472
 
First Author: Ni X
Year: 2018
Journal: Front Immunol
Title: Cytokine-Based Generation of CD49a+Eomes-/+ Natural Killer Cell Subsets.
Volume: 9
Pages: 2126
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Publication
22504655 | J:188669
First Author: Tofukuji S
Year: 2012
Journal: J Immunol
Title: Identification of a new pathway for Th1 cell development induced by cooperative stimulation with IL-4 and TGF-β.
Volume: 188
Issue: 10
Pages: 4846-57
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Publication
30814306 | J:274339
First Author: Millan AJ
Year: 2019
Journal: J Immunol
Title: Sostdc1 Regulates NK Cell Maturation and Cytotoxicity.
Volume: 202
Issue: 8
Pages: 2296-2306
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Publication
19688743 | J:154199
First Author: Ju S
Year: 2009
Journal: Eur J Immunol
Title: Gadd45b and Gadd45g are important for anti-tumor immune responses.
Volume: 39
Issue: 11
Pages: 3010-8
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Publication
20980403 | J:168150
First Author: Lin SC
Year: 2010
Journal: Development
Title: Klf5 regulates lineage formation in the pre-implantation mouse embryo.
Volume: 137
Issue: 23
Pages: 3953-63
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Publication
27298446 | J:236254
First Author: Renkema KR
Year: 2016
Journal: J Exp Med
Title: IL-4 sensitivity shapes the peripheral CD8+ T cell pool and response to infection.
Volume: 213
Issue: 7
Pages: 1319-29
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Publication
28765163 | J:252135
First Author: Albert M
Year: 2017
Journal: EMBO J
Title: Epigenome profiling and editing of neocortical progenitor cells during development.
Volume: 36
Issue: 17
Pages: 2642-2658
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Publication
24628083 | J:212000
First Author: Kim JH
Year: 2014
Journal: Immunology
Title: Lack of transglutaminase 2 diminished T-cell responses in mice.
Volume: 142
Issue: 3
Pages: 506-16
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Publication
21632880 | J:180827
First Author: David R
Year: 2011
Journal: Cardiovasc Res
Title: Induction of MesP1 by Brachyury(T) generates the common multipotent cardiovascular stem cell.
Volume: 92
Issue: 1
Pages: 115-22
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Publication
9888994 | J:52301
First Author: Yi CH
Year: 1999
Journal: Genomics
Title: Identification, mapping, and phylogenomic analysis of four new human members of the T-box gene family: EOMES, TBX6, TBX18, and TBX19.
Volume: 55
Issue: 1
Pages: 10-20
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Publication
19542449 | J:149971
First Author: Curtis MM
Year: 2009
Journal: J Immunol
Title: IL-23 promotes the production of IL-17 by antigen-specific CD8 T cells in the absence of IL-12 and type-I interferons.
Volume: 183
Issue: 1
Pages: 381-7
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Publication
21478404 | J:173091
First Author: Min HS
Year: 2011
Journal: J Immunol
Title: MHC class II-restricted interaction between thymocytes plays an essential role in the production of innate CD8+ T cells.
Volume: 186
Issue: 10
Pages: 5749-57
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Publication
22623621 | J:192429
First Author: Koch Y
Year: 2012
Journal: Biol Reprod
Title: Connexin 31 (GJB3) deficiency in mouse trophoblast stem cells alters giant cell differentiation and leads to loss of oxygen sensing.
Volume: 87
Issue: 2
Pages: 37
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Publication
25550515 | J:218909
First Author: Leavenworth JW
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Intracellular osteopontin regulates homeostasis and function of natural killer cells.
Volume: 112
Issue: 2
Pages: 494-9
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Publication
24231259 | J:329705
First Author: Mollo SB
Year: 2014
Journal: J Leukoc Biol
Title: Virus-specific CD4 and CD8 T cell responses in the absence of Th1-associated transcription factors.
Volume: 95
Issue: 5
Pages: 705-713
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Publication
35008461 | J:331160
 
First Author: Ara A
Year: 2021
Journal: Int J Mol Sci
Title: The Energy Sensor AMPKα1 Is Critical in Rapamycin-Inhibition of mTORC1-S6K-Induced T-cell Memory.
Volume: 23
Issue: 1
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Publication
36442116 | J:334435
First Author: Rodriguez-Rodriguez N
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: Identification of aceNKPs, a committed common progenitor population of the ILC1 and NK cell continuum.
Volume: 119
Issue: 49
Pages: e2203454119
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Publication
30071007 | J:264365
First Author: Zhang P
Year: 2018
Journal: PLoS One
Title: Brain region-dependent gene networks associated with selective breeding for increased voluntary wheel-running behavior.
Volume: 13
Issue: 8
Pages: e0201773
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Publication
- | J:100256
     
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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