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Search results 201 to 222 out of 222 for Trak1

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0.019s

Type

Details

Score

Protein

Q6P9N8

Organism:	Mus musculus/domesticus
Length:	913
Fragment?:	false

•

Strain

MGI:5703893 | C57BL/6N-Tg(Cck-EGFP/RNAi:Gad1)2Mirn/J

Attribute String:

transgenic, mutant strain, coisogenic

•

Strain

MGI:5704118 | C57BL/6NHsd-Tg(Cck-EGFP/RNAi:Gad1)2Mirn

Attribute String:

transgenic, mutant strain, coisogenic

•

Genotype

Symbol:	Tg(Cck-EGFP/RNAi:Gad1)2Mirn/?
Background:	C57BL/6NHsd-Tg(Cck-EGFP/RNAi:Gad1)2Mirn
Zygosity:	ot
Has Mutant Allele:	true

•

Publication

9599014 | J:47245

First Author:	Bertaux F
Year:	1998
Journal:	FEBS Lett
Title:	HAP1-huntingtin interactions do not contribute to the molecular pathology in Huntington's disease transgenic mice.
Volume:	426
Issue:	2
Pages:	229-32

•

Protein

O35668

Organism:	Mus musculus/domesticus
Length:	628
Fragment?:	false

•

Protein

G3UYE4

Organism:	Mus musculus/domesticus
Length:	326
Fragment?:	true

•

Protein

G3UZT4

Organism:	Mus musculus/domesticus
Length:	181
Fragment?:	true

•

Protein

A0A1B0GRL4

Organism:	Mus musculus/domesticus
Length:	241
Fragment?:	true

•

Protein

Q8BWK8

Organism:	Mus musculus/domesticus
Length:	304
Fragment?:	false

•

Protein

A0A1B0GSC9

Organism:	Mus musculus/domesticus
Length:	24
Fragment?:	true

•

Publication

7477378 | -

First Author:	Li XJ
Year:	1995
Journal:	Nature
Title:	A huntingtin-associated protein enriched in brain with implications for pathology.
Volume:	378
Issue:	6555
Pages:	398-402

•

Publication

22731248 | J:187639

First Author:	Yang GZ
Year:	2012
Journal:	J Neurochem
Title:	Huntingtin associated protein 1 regulates trafficking of the amyloid precursor protein and modulates amyloid beta levels in neurons.
Volume:	122
Issue:	5
Pages:	1010-22

•

Publication

19262167 | -

First Author:	Wu LL
Year:	2009
Journal:	Cell Adh Migr
Title:	Huntingtin associated protein 1 and its functions.
Volume:	3
Issue:	1
Pages:	71-6

•

Publication

27737633 | -

First Author:	Lumsden AL
Year:	2016
Journal:	BMC Evol Biol
Title:	Huntingtin-associated protein 1: Eutherian adaptation from a TRAK-like protein, conserved gene promoter elements, and localization in the human intestine.
Volume:	16
Issue:	1
Pages:	214

•

Protein Domain

IPR006933 | HAP1_N

Type:

Domain

Description:

This entry represents a N-terminal conserved region found in huntingtin-associated protein 1 (HAP1), trafficking Kinesin proteins TRAK1 and TRAK2 (vertebrate), Milton (Drosophila) and T27A3.1 (C. elegans) []. HAP1 binds to huntingtin in a polyglutamine repeat-length-dependent manner [, , ]. It is involved in intracellular trafficking []. HAP1 is also linked to Alzheimer's disease. It regulates amyloid precursor protein subcellular trafficking to the non-amyloidogenic pathway and may negatively regulate Abeta production in neurons [].TRAK1 binds to both kinesin-1 and dynein/dynactin, is prominently localized in axons, and is needed for normal axon outgrowth, whereas TRAK2 predominantly interacts with dynein/dynactin, is more abundantly present in dendrites, and is required for dendritic development [].

•

Publication

29311115 | J:317069

First Author:	López-Doménech G
Year:	2018
Journal:	EMBO J
Title:	Miro proteins coordinate microtubule- and actin-dependent mitochondrial transport and distribution.
Volume:	37
Issue:	3
Pages:	321-336

•

Publication

24322205 | J:227900

First Author:	Schmidt MJ
Year:	2014
Journal:	Mol Psychiatry
Title:	Modulation of behavioral networks by selective interneuronal inactivation.
Volume:	19
Issue:	5
Pages:	580-7

•

Publication

9285789 | -

First Author:	Colomer V
Year:	1997
Journal:	Hum Mol Genet
Title:	Huntingtin-associated protein 1 (HAP1) binds to a Trio-like polypeptide, with a rac1 guanine nucleotide exchange factor domain.
Volume:	6
Issue:	9
Pages:	1519-25

•

Publication

15489334 | -

First Author:	Gerhard DS
Year:	2004
Journal:	Genome Res
Title:	The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume:	14
Issue:	10B
Pages:	2121-7

•

Publication

21183079 | J:292518

First Author:	Huttlin EL
Year:	2010
Journal:	Cell
Title:	A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume:	143
Issue:	7
Pages:	1174-89

•

Publication

19468303 | -

First Author:	Church DM
Year:	2009
Journal:	PLoS Biol
Title:	Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume:	7
Issue:	5
Pages:	e1000112

•

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