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Search results 101 to 200 out of 306 for Pcsk2

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Type Details Score
GXD Expression
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 7
Image: 5E
Note: Expression clearly appears starting on days P3-P14.
Specimen Label: 5E
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 11
Image: 5F
Note: Expression increases during prenatal and postnatal periods.
Specimen Label: 5F
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 11
Image: 5F
Note: Maximal expression at P11.
Specimen Label: 5F
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal adult
Image: 5G
Note: Expression reaches a plateau at adulthood.
Specimen Label: 5G
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal adult
Image: 5G
Note: Expression decreases toward adulthood. Authors report expression in Acth (alphaMSH, POMC))-expressing cells.
Specimen Label: 5G
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 7
Image: 5I
Note: Authors report expression in alphaMSH (Acth)-expressing cells.
Specimen Label: 5I
Detected: true
Specimen Num: 8
GXD Expression      
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1664718
Stage: TS18
Assay Id: MGI:5707150
Age: embryonic day 11.0
Specimen Label: Table 1 E11
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751620
Stage: TS20
Assay Id: MGI:5707150
Age: embryonic day 12.0
Specimen Label: Table 1 E12
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751520
Stage: TS20
Assay Id: MGI:5707150
Age: embryonic day 12.0
Specimen Label: Table 1 E12
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751621
Stage: TS21
Assay Id: MGI:5707150
Age: embryonic day 13.0
Specimen Label: Table 1 E13
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751521
Stage: TS21
Assay Id: MGI:5707150
Age: embryonic day 13.0
Specimen Label: Table 1 E13
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751622
Stage: TS22
Assay Id: MGI:5707150
Age: embryonic day 14.0
Specimen Label: Table 1 E14
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751522
Stage: TS22
Assay Id: MGI:5707150
Age: embryonic day 14.0
Specimen Label: Table 1 E14
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751623
Stage: TS23
Assay Id: MGI:5707150
Age: embryonic day 15.0
Specimen Label: Table 1 E15
Detected: false
Specimen Num: 13
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1751523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5707150
Age: embryonic day 15.0
Specimen Label: Table 1 E15
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5707150
Age: embryonic day 16.0
Specimen Label: Table 1 E16
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1751524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5707150
Age: embryonic day 16.0
Specimen Label: Table 1 E16
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5707150
Age: embryonic day 17.0
Specimen Label: Table 1 E17
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1751525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5707150
Age: embryonic day 17.0
Specimen Label: Table 1 E17
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5707150
Age: embryonic day 18.0
Specimen Label: Table 1 E18
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1751526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5707150
Age: embryonic day 18.0
Specimen Label: Table 1 E18
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5707150
Age: embryonic day 20.0
Specimen Label: Table 1 E20
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1751526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5707150
Age: embryonic day 20.0
Specimen Label: Table 1 E20
Detected: true
Specimen Num: 17
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1751627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5707150
Age: postnatal day 1
Specimen Label: Table 1 P1
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5707150
Age: postnatal day 1
Specimen Label: Table 1 P1
Detected: true
Specimen Num: 18
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707150
Age: postnatal day 7
Specimen Label: Table 1 P7
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707150
Age: postnatal day 7
Specimen Label: Table 1 P7
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707150
Age: postnatal day 14
Specimen Label: Table 1 P14
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707150
Age: postnatal day 14
Specimen Label: Table 1 P14
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707150
Age: postnatal adult
Specimen Label: Table 1 Adult
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:5707013
Assay Type: RNA in situ
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707150
Age: postnatal adult
Specimen Label: Table 1 Adult
Detected: true
Specimen Num: 21
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1664718
Stage: TS18
Assay Id: MGI:5707154
Age: embryonic day 11.0
Specimen Label: Table 1 E11
Detected: false
Specimen Num: 9
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751620
Stage: TS20
Assay Id: MGI:5707154
Age: embryonic day 12.0
Specimen Label: Table 1 E12
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751520
Stage: TS20
Assay Id: MGI:5707154
Age: embryonic day 12.0
Specimen Label: Table 1 E12
Detected: false
Specimen Num: 10
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751621
Stage: TS21
Assay Id: MGI:5707154
Age: embryonic day 13.0
Specimen Label: Table 1 E13
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751521
Stage: TS21
Assay Id: MGI:5707154
Age: embryonic day 13.0
Specimen Label: Table 1 E13
Detected: false
Specimen Num: 11
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751622
Stage: TS22
Assay Id: MGI:5707154
Age: embryonic day 14.0
Specimen Label: Table 1 E14
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751522
Stage: TS22
Assay Id: MGI:5707154
Age: embryonic day 14.0
Specimen Label: Table 1 E14
Detected: false
Specimen Num: 12
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751623
Stage: TS23
Assay Id: MGI:5707154
Age: embryonic day 15.0
Specimen Label: Table 1 E15
Detected: false
Specimen Num: 13
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751523
Stage: TS23
Assay Id: MGI:5707154
Age: embryonic day 15.0
Specimen Label: Table 1 E15
Detected: false
Specimen Num: 13
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1751624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:5707154
Age: embryonic day 16.0
Specimen Label: Table 1 E16
Detected: true
Specimen Num: 14
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751524
Stage: TS24
Assay Id: MGI:5707154
Age: embryonic day 16.0
Specimen Label: Table 1 E16
Detected: false
Specimen Num: 14
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751625
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5707154
Age: embryonic day 17.0
Specimen Label: Table 1 E17
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1751525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5707154
Age: embryonic day 17.0
Specimen Label: Table 1 E17
Specimen Num: 15
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5707154
Age: embryonic day 18.0
Specimen Label: Table 1 E18
Detected: true
Specimen Num: 16
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1751526
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5707154
Age: embryonic day 18.0
Specimen Label: Table 1 E18
Specimen Num: 16
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5707154
Age: embryonic day 20.0
Specimen Label: Table 1 E20
Detected: true
Specimen Num: 17
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751526
Stage: TS26
Assay Id: MGI:5707154
Age: embryonic day 20.0
Specimen Label: Table 1 E20
Detected: false
Specimen Num: 17
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5707154
Age: postnatal day 1
Specimen Label: Table 1 P1
Detected: true
Specimen Num: 18
GXD Expression      
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751527
Stage: TS27
Assay Id: MGI:5707154
Age: postnatal day 1
Specimen Label: Table 1 P1
Detected: false
Specimen Num: 18
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 5
Specimen Label: Table 1 P5
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 7
Specimen Label: Table 1 P7
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 9
Specimen Label: Table 1 P9
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 9
Specimen Label: Table 1 P9
Detected: true
Specimen Num: 22
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 11
Specimen Label: Table 1 P11
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 11
Specimen Label: Table 1 P11
Detected: true
Specimen Num: 23
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 14
Specimen Label: Table 1 P14
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 14
Specimen Label: Table 1 P14
Detected: true
Specimen Num: 24
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal adult
Specimen Label: Table 1 Adult
Detected: true
Specimen Num: 25
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1751528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal adult
Specimen Label: Table 1 Adult
Detected: true
Specimen Num: 25
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:1751527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5707154
Age: postnatal day 3
Specimen Label: Table 1 P3
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:5707154
Age: postnatal day 3
Specimen Label: Table 1 P3
Detected: true
Specimen Num: 19
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 5
Specimen Label: Table 1 P5
Detected: true
Specimen Num: 20
GXD Expression    
Probe: MGI:5707019
Assay Type: Immunohistochemistry
Annotation Date: 2016-02-03
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5707154
Age: postnatal day 7
Specimen Label: Table 1 P7
Detected: true
Specimen Num: 21
GXD Expression    
Probe: MGI:288259
Assay Type: RNA in situ
Annotation Date: 2019-01-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:6273897
Age: embryonic day 14.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6180267
Assay Type: RNA in situ
Annotation Date: 2019-01-24
Strength: Present
Sex: Male
Emaps: EMAPS:3270324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6274558
Age: embryonic day 15.5
Specimen Label: Table S1
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6376523
Assay Type: Immunohistochemistry
Annotation Date: 2019-11-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751626
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6376605
Age: embryonic day 18.5
Image: 6E
Note: Expression in intermediate lobe
Specimen Label: 6E
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6376523
Assay Type: Immunohistochemistry
Annotation Date: 2019-11-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1751626
Stage: TS26
Assay Id: MGI:6376605
Age: embryonic day 18.5
Image: 6F
Specimen Label: 6F
Detected: false
Specimen Num: 2
GXD Expression
Probe: MGI:6380533
Assay Type: Immunohistochemistry
Annotation Date: 2019-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:6380639
Age: embryonic day 18.5
Image: 2G
Note: Expression in melanotropes.
Specimen Label: 2G
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6380533
Assay Type: Immunohistochemistry
Annotation Date: 2019-12-13
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:3599826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6380639
Age: embryonic day 18.5
Image: 2H
Note: Expression nearly undetectable.
Specimen Label: 2H
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:6471700
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751624
Pattern: Widespread
Stage: TS24
Assay Id: MGI:6471713
Age: embryonic day 16.5
Image: 2M
Note: Expression in melanotrophes throughout intermediate lobe.
Specimen Label: 2M
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:6471700
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-12
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1751624
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6471713
Age: embryonic day 16.5
Image: 2N
Note: Very few, if any, cells in the intermediate lobe differentiate into melanotropes
Specimen Label: 2N
Specimen Num: 2
GXD Expression
Probe: MGI:6471700
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751624
Pattern: Single cells
Stage: TS24
Assay Id: MGI:6471713
Age: embryonic day 16.5
Image: 2O
Note: Occasional expressing cell.
Specimen Label: 2O
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6471700
Assay Type: Immunohistochemistry
Annotation Date: 2020-11-12
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3599824
Stage: TS24
Assay Id: MGI:6471713
Age: embryonic day 16.5
Image: 2P
Note: Entire mutant pituitary gland is devoid of expression.
Specimen Label: 2P
Detected: false
Specimen Num: 4
GXD Expression  
Probe: MGI:7525900
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7526046
Age: embryonic day 18.5
Image: 4Bu
Specimen Label: 4Bu
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:7525900
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:7526046
Age: embryonic day 18.5
Image: 4Bv
Specimen Label: 4Bv
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:7525900
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7526046
Age: embryonic day 18.5
Image: 4Bw
Note: Expression in patches of cells in dysmorphic intermediate lobe.
Specimen Label: 4Bw
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:7525900
Assay Type: Immunohistochemistry
Annotation Date: 2023-09-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1751626
Pattern: Regionally restricted
Stage: TS26
Assay Id: MGI:7526046
Age: embryonic day 18.5
Image: 4Bx
Note: Expression in same subset of cells as in single Wnt5a mutant.
Specimen Label: 4Bx
Detected: true
Specimen Num: 4
Publication
First Author: Westphal CH
Year: 1999
Journal: Cell
Title: The neuroendocrine protein 7B2 is required for peptide hormone processing in vivo and provides a novel mechanism for pituitary Cushing's disease.
Volume: 96
Issue: 5
Pages: 689-700
Publication
First Author: Furuta M
Year: 2001
Journal: J Biol Chem
Title: Severe defect in proglucagon processing in islet A-cells of prohormone convertase 2 null mice.
Volume: 276
Issue: 29
Pages: 27197-202
Publication
First Author: Seidah NG
Year: 1991
Journal: Mol Endocrinol
Title: Cloning and primary sequence of a mouse candidate prohormone convertase PC1 homologous to PC2, Furin, and Kex2: distinct chromosomal localization and messenger RNA distribution in brain and pituitary compared to PC2.
Volume: 5
Issue: 1
Pages: 111-22
Publication
First Author: Seidah NG
Year: 1990
Journal: DNA Cell Biol
Title: cDNA sequence of two distinct pituitary proteins homologous to Kex2 and furin gene products: tissue-specific mRNAs encoding candidates for pro-hormone processing proteinases.
Volume: 9
Issue: 6
Pages: 415-24
Publication
First Author: Wardman JH
Year: 2010
Journal: J Neurochem
Title: Analysis of peptides in prohormone convertase 1/3 null mouse brain using quantitative peptidomics.
Volume: 114
Issue: 1
Pages: 215-25
Publication
First Author: Hardiman A
Year: 2005
Journal: J Mol Endocrinol
Title: Endocrinomic profile of neurointermediate lobe pituitary prohormone processing in PC1/3- and PC2-Null mice using SELDI-TOF mass spectrometry.
Volume: 34
Issue: 3
Pages: 739-51
Publication
First Author: Laurent V
Year: 2004
Journal: Endocrinology
Title: Biosynthesis of proopiomelanocortin-derived peptides in prohormone convertase 2 and 7B2 null mice.
Volume: 145
Issue: 2
Pages: 519-28
Publication
First Author: Helwig M
Year: 2011
Journal: J Biol Chem
Title: Dynamic modulation of prohormone convertase 2 (PC2)-mediated precursor processing by 7B2 protein: preferential effect on glucagon synthesis.
Volume: 286
Issue: 49
Pages: 42504-13
Publication
First Author: Peinado JR
Year: 2005
Journal: Endocrinology
Title: Strain-dependent influences on the hypothalamo-pituitary-adrenal axis profoundly affect the 7B2 and PC2 null phenotypes.
Volume: 146
Issue: 8
Pages: 3438-44
Publication
First Author: Vishnuvardhan D
Year: 2000
Journal: Biochem Biophys Res Commun
Title: PC2 and 7B2 null mice demonstrate that PC2 is essential for normal pro-CCK processing.
Volume: 273
Issue: 1
Pages: 188-91
Publication
First Author: Laurent V
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Mortality in 7B2 null mice can be rescued by adrenalectomy: involvement of dopamine in ACTH hypersecretion.
Volume: 99
Issue: 5
Pages: 3087-92
Publication
First Author: Rehfeld JF
Year: 2002
Journal: FEBS Lett
Title: Progastrin processing differs in 7B2 and PC2 knockout animals: a role for 7B2 independent of action on PC2.
Volume: 510
Issue: 1-2
Pages: 89-93
Publication
First Author: Beinfeld MC
Year: 2005
Journal: J Biol Chem
Title: Cholecystokinin levels in prohormone convertase 2 knock-out mouse brain regions reveal a complex phenotype of region-specific alterations.
Volume: 280
Issue: 46
Pages: 38410-5
Publication
First Author: Wang J
Year: 2001
Journal: Diabetes
Title: The prohormone convertase enzyme 2 (PC2) is essential for processing pro-islet amyloid polypeptide at the NH2-terminal cleavage site.
Volume: 50
Issue: 3
Pages: 534-9
Publication
First Author: Fujita Y
Year: 2010
Journal: Gastroenterology
Title: Glucose-dependent insulinotropic polypeptide is expressed in pancreatic islet alpha-cells and promotes insulin secretion.
Volume: 138
Issue: 5
Pages: 1966-75
Publication
First Author: Miller R
Year: 2003
Journal: J Neurochem
Title: Obliteration of alpha-melanocyte-stimulating hormone derived from POMC in pituitary and brains of PC2-deficient mice.
Volume: 86
Issue: 3
Pages: 556-63
Publication
First Author: Ni XP
Year: 2003
Journal: J Clin Invest
Title: Genetic disruption of gamma-melanocyte-stimulating hormone signaling leads to salt-sensitive hypertension in the mouse.
Volume: 111
Issue: 8
Pages: 1251-8
Publication
First Author: Poirier S
Year: 2006
Journal: J Neurochem
Title: Implication of the proprotein convertase NARC-1/PCSK9 in the development of the nervous system.
Volume: 98
Issue: 3
Pages: 838-50
Publication
First Author: Breslin MB
Year: 1993
Journal: J Biol Chem
Title: Differential processing of proenkephalin by prohormone convertases 1(3) and 2 and furin.
Volume: 268
Issue: 36
Pages: 27084-93
Publication  
First Author: Benjannet S
Year: 1993
Journal: Biochem J
Title: Comparative biosynthesis, covalent post-translational modifications and efficiency of prosegment cleavage of the prohormone convertases PC1 and PC2: glycosylation, sulphation and identification of the intracellular site of prosegment cleavage of PC1 and PC2.
Volume: 294 ( Pt 3)
Pages: 735-43
Publication
First Author: Smeekens SP
Year: 1991
Journal: Proc Natl Acad Sci U S A
Title: Identification of a cDNA encoding a second putative prohormone convertase related to PC2 in AtT20 cells and islets of Langerhans.
Volume: 88
Issue: 2
Pages: 340-4
Publication
First Author: Marcinkiewicz M
Year: 1994
Journal: Endocrinology
Title: Developmental expression of the prohormone convertases PC1 and PC2 in mouse pancreatic islets.
Volume: 135
Issue: 4
Pages: 1651-60