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Search results 701 to 800 out of 949 for Alk

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Type Details Score
Publication
29046432 | J:248299
 
First Author: Zeng L
Year: 2017
Journal: Sci Transl Med
Title: ALK is a therapeutic target for lethal sepsis.
Volume: 9
Issue: 412
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Allele
Alk<tm1.1Rhp> | MGI:5700375
Name: anaplastic lymphoma kinase; targeted mutation 1.1, Ruth H Palmer
Allele Type: Targeted
Attribute String: Null/knockout
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HT Experiment
E-GEOD-46584 | Expression data from sympathetic nervous system of KI Alk F1178L mice
Series Id: GSE46584
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Protein
D3Z3D0
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 26
Description: ALK and LTK ligand 2
Type: chain
End: 151
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UniProt Feature
UniProt Feature
Begin: 28
Description: ALK and LTK ligand 1
Type: chain
End: 127
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Publication
19249873 | J:149248
First Author: Lu L
Year: 2009
Journal: Biochemistry
Title: ALK mutants in the kinase domain exhibit altered kinase activity and differential sensitivity to small molecule ALK inhibitors.
Volume: 48
Issue: 16
Pages: 3600-9
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Publication
21156280 | J:167436
First Author: Gerber DE
Year: 2010
Journal: Cancer Cell
Title: ALK inhibition for non-small cell lung cancer: from discovery to therapy in record time.
Volume: 18
Issue: 6
Pages: 548-51
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Publication
16878150 | -
First Author: Kuo AH
Year: 2007
Journal: Oncogene
Title: Recruitment of insulin receptor substrate-1 and activation of NF-kappaB essential for midkine growth signaling through anaplastic lymphoma kinase.
Volume: 26
Issue: 6
Pages: 859-69
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Publication
19459784 | -
First Author: Palmer RH
Year: 2009
Journal: Biochem J
Title: Anaplastic lymphoma kinase: signalling in development and disease.
Volume: 420
Issue: 3
Pages: 345-61
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Protein
H3BKM2
Organism: Mus musculus/domesticus
Length: 459  
Fragment?: false
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Protein
D3Z0B2
Organism: Mus musculus/domesticus
Length: 49  
Fragment?: false
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Protein
D3Z5A4
Organism: Mus musculus/domesticus
Length: 45  
Fragment?: true
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Publication
38741708 | J:351993
First Author: Bugide S
Year: 2024
Journal: iScience
Title: ALK inhibitors suppress HCC and synergize with anti-PD-1 therapy and ABT-263 in preclinical models.
Volume: 27
Issue: 5
Pages: 109800
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Publication
29669761 | J:262592
First Author: Yun MR
Year: 2018
Journal: Cancer Res
Title: Enhancer Remodeling and MicroRNA Alterations Are Associated with Acquired Resistance to ALK Inhibitors.
Volume: 78
Issue: 12
Pages: 3350-3362
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Gene
108716096 | alk.L
Type: gene
Organism: frog, African clawed
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Gene
108716378 | alkal2.L
Type: gene
Organism: frog, African clawed
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Gene
108717382 | alk.S
Type: gene
Organism: frog, African clawed
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Gene
108718224 | alkal2.S
Type: gene
Organism: frog, African clawed
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Gene
121395158 | alkal1.S
Type: gene
Organism: frog, African clawed
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Pathway
R-MMU-201556 | Signaling by ALK
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Publication
22696294 | J:185584
First Author: Illert AL
Year: 2012
Journal: Development
Title: Targeted inactivation of nuclear interaction partner of ALK disrupts meiotic prophase.
Volume: 139
Issue: 14
Pages: 2523-34
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Interaction Experiment
Motegi A (2004)
Description: ALK receptor tyrosine kinase promotes cell growth and neurite outgrowth.
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Publication
35412887 | J:324631
First Author: Ahmed M
Year: 2022
Journal: Proc Natl Acad Sci U S A
Title: A hypothalamic pathway for Augmentor α-controlled body weight regulation.
Volume: 119
Issue: 16
Pages: e2200476119
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Allele
Alkal1<+> | MGI:3659287
 
Name: ALK and LTK ligand 1; wild type
Allele Type: Not Specified
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Allele
Alkal2<+> | MGI:3843935
 
Name: ALK and LTK ligand 2; wild type
Allele Type: Not Specified
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Publication
26710715 | J:229545
 
First Author: Saville JT
Year: 2016
Journal: Exp Neurol
Title: Selective normalisation of regional brain bis(monoacylglycero)phosphate in the mucopolysaccharidosis 1 (Hurler) mouse.
Volume: 277
Pages: 68-75
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Publication
31431076 | J:299165
First Author: Nouri K
Year: 2019
Journal: FASEB J
Title: A kinome-wide screen using a NanoLuc LATS luminescent biosensor identifies ALK as a novel regulator of the Hippo pathway in tumorigenesis and immune evasion.
Volume: 33
Issue: 11
Pages: 12487-12499
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Allele
Alkal1<Gt(RRK010)Byg> | MGI:4129168
 
Name: ALK and LTK ligand 1; gene trap RRK010, BayGenomics
Allele Type: Gene trapped
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Allele
Alkal1<tm1Lex> | MGI:5007128
Name: ALK and LTK ligand 1; targeted mutation 1, Lexicon Pharmaceuticals
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Alkal2<em1(IMPC)J> | MGI:7328421
Name: ALK and LTK ligand 2; endonuclease-mediated mutation 1, Jackson
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Allele
Alkal2<tm1Schl> | MGI:7578836
Name: ALK and LTK ligand 2; targeted mutation 1, Joseph Schlessinger
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Allele
Alkal1<tm1Schl> | MGI:7578839
Name: ALK and LTK ligand 1; targeted mutation 1, Joseph Schlessinger
Allele Type: Targeted
Attribute String: Null/knockout, Reporter
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Protein Coding Gene
MGP_CAROLIEiJ_G0013931 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_CAROLIEiJ_G0017669 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0015819 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_129S1SvImJ_G0019653 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0015801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019620 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0015760 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0015757 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019597 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0015591 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019401 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3645495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3697448 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016209 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0020044 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015171 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019372 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0015663 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019486 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0015668 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019477 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0015736 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019556 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0015687 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019512 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016256 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0020084 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0014955 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015235 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0019007 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023887 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_PahariEiJ_G0029427 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0014735 | -
Type: protein_coding_gene
Organism: Mus spretus
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Protein Coding Gene
MGP_SPRETEiJ_G0018511 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Stage: TS23
Assay Id: MGI:7544035
Age: embryonic day 15.5
Image: EV1
Specimen Label: E15.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7544035
Age: postnatal day 0
Image: EV1
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Stage: TS27
Assay Id: MGI:7544035
Age: postnatal day 2
Image: EV1
Specimen Label: P2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7544035
Age: postnatal day 7
Image: EV1
Specimen Label: P7
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7544035
Age: postnatal adult
Image: EV1
Specimen Label: Adult
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7544037
Age: embryonic day 15.5
Image: EV1
Specimen Label: E15.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7544037
Age: postnatal day 0
Image: EV1
Specimen Label: P0
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:7544037
Age: postnatal day 2
Image: EV1
Specimen Label: P2
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544037
Age: postnatal day 7
Image: EV1
Specimen Label: P7
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544037
Age: postnatal adult
Image: EV1
Specimen Label: Adult
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7544916
Age: embryonic day 15.5
Image: EV3
Specimen Label: E15.5 WT
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544916
Age: postnatal day 20
Image: EV3
Specimen Label: P20 WT
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544916
Age: postnatal month 3-6
Image: EV3
Specimen Label: Adult WT
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Stage: TS23
Assay Id: MGI:7544916
Age: embryonic day 15.5
Image: EV3
Specimen Label: E15.5 DKO
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544916
Age: postnatal day 20
Image: EV3
Specimen Label: P20 DKO
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:7543997
Assay Type: RT-PCR
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:7544916
Age: postnatal month 3-6
Image: EV3
Specimen Label: Adult DKO
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1B
Specimen Label: EV1B
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1A
Specimen Label: EV1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1D
Specimen Label: EV1D
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Specimen Label: EV1E
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3585923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Note: Expression was detected in the ventrolateral thalamic nucleus.
Specimen Label: EV1E
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753623
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Note: Expression was detected in the hypothalamic area.
Specimen Label: EV1E
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754423
Pattern: Widespread
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1A
Specimen Label: EV1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Note: Expression was detected in the amygdaloid area.
Specimen Label: EV1E
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1A
Specimen Label: EV1A
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1D
Specimen Label: EV1D
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3280923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1E
Note: Expression was detected in the lateral olfactory bulb.
Specimen Label: EV1E
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7544009
Assay Type: RNA in situ
Annotation Date: 2023-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689423
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:7544901
Age: embryonic day 15.5
Image: EV1F
Specimen Label: EV1F
Detected: true
Specimen Num: 5
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Pathway
R-MMU-9701898 | STAT3 nuclear events downstream of ALK signaling
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Pathway
R-MMU-9851151 | MDK and PTN in ALK signaling
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