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Search results 101 to 200 out of 649 for Ikbkb

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Type Details Score
Publication
16397523 | J:105714
First Author: Stratis A
Year: 2006
Journal: J Invest Dermatol
Title: Localized inflammatory skin disease following inducible ablation of I kappa B kinase 2 in murine epidermis.
Volume: 126
Issue: 3
Pages: 614-20
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Publication
14755344 | J:87587
First Author: Röhl M
Year: 2004
Journal: J Clin Invest
Title: Conditional disruption of IkappaB kinase 2 fails to prevent obesity-induced insulin resistance.
Volume: 113
Issue: 3
Pages: 474-81
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Publication
24078701 | J:206232
First Author: Perez-Nazario N
Year: 2013
Journal: J Immunol
Title: Selective ablation of lung epithelial IKK2 impairs pulmonary Th17 responses and delays the clearance of Pneumocystis.
Volume: 191
Issue: 9
Pages: 4720-30
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Publication
31088970 | J:276525
First Author: Ochaba J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: IKKβ slows Huntington's disease progression in R6/1 mice.
Volume: 116
Issue: 22
Pages: 10952-10961
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Publication
20007573 | J:157463
First Author: Emmanouil M
Year: 2009
Journal: J Immunol
Title: Neuronal I kappa B kinase beta protects mice from autoimmune encephalomyelitis by mediating neuroprotective and immunosuppressive effects in the central nervous system.
Volume: 183
Issue: 12
Pages: 7877-89
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Publication
26987064 | J:249075
First Author: Chen L
Year: 2016
Journal: PLoS One
Title: Corneal Wound Healing Requires IKB kinase β Signaling in Keratocytes.
Volume: 11
Issue: 3
Pages: e0151869
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Publication
10359587 | J:55737
First Author: Li ZW
Year: 1999
Journal: J Exp Med
Title: The IKKbeta subunit of IkappaB kinase (IKK) is essential for nuclear factor kappaB activation and prevention of apoptosis.
Volume: 189
Issue: 11
Pages: 1839-45
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Publication
17116751 | J:119008
First Author: Song L
Year: 2006
Journal: J Cell Biol
Title: IKKbeta programs to turn on the GADD45alpha-MKK4-JNK apoptotic cascade specifically via p50 NF-kappaB in arsenite response.
Volume: 175
Issue: 4
Pages: 607-17
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Publication
11713531 | J:72834
First Author: Tang G
Year: 2001
Journal: Nature
Title: Inhibition of JNK activation through NF-kappaB target genes.
Volume: 414
Issue: 6861
Pages: 313-7
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Publication
17118453 | J:116109
First Author: Wang J
Year: 2007
Journal: Mol Immunol
Title: IKK antagonizes CD95 ligation-mediated apoptosis by regulating NF-kappaB activity.
Volume: 44
Issue: 8
Pages: 2139-43
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Publication
- | J:274802
     
First Author: Zhong X
Year: 2019
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for Baby.
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Publication
34454938 | J:312968
 
First Author: Bantle CM
Year: 2021
Journal: Exp Neurol
Title: Astrocyte inflammatory signaling mediates α-synuclein aggregation and dopaminergic neuronal loss following viral encephalitis.
Volume: 346
Pages: 113845
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Publication
36001064 | J:336399
First Author: Silva VRR
Year: 2022
Journal: FASEB J
Title: Somatic ablation of IKKβ in liver and leukocytes is not tolerated in obese mice but hepatic IKKβ deletion improves fatty liver and insulin sensitivity.
Volume: 36
Issue: 9
Pages: e22512
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Publication
25297800 | J:219235
First Author: Kyrargyri V
Year: 2015
Journal: Glia
Title: Differential contributions of microglial and neuronal IKKβ to synaptic plasticity and associative learning in alert behaving mice.
Volume: 63
Issue: 4
Pages: 549-66
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Publication
30043530 | J:266203
First Author: Kim JH
Year: 2018
Journal: Glia
Title: Astroglia contribute to the pathogenesis of spinocerebellar ataxia Type 1 (SCA1) in a biphasic, stage-of-disease specific manner.
Volume: 66
Issue: 9
Pages: 1972-1987
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Publication
30818064 | J:279784
 
First Author: Kirkley KS
Year: 2019
Journal: Neurobiol Dis
Title: Genetic suppression of IKK2/NF-κB in astrocytes inhibits neuroinflammation and reduces neuronal loss in the MPTP-Probenecid model of Parkinson's disease.
Volume: 127
Pages: 193-209
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Publication
19171122 | J:146133
First Author: Koch KS
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Targeted deletion of hepatocyte Ikkbeta confers growth advantages.
Volume: 380
Issue: 2
Pages: 349-54
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Publication
15685170 | J:95947
First Author: Arkan MC
Year: 2005
Journal: Nat Med
Title: IKK-beta links inflammation to obesity-induced insulin resistance.
Volume: 11
Issue: 2
Pages: 191-8
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Publication
14614859 | J:113596
First Author: Maeda S
Year: 2003
Journal: Immunity
Title: IKKbeta is required for prevention of apoptosis mediated by cell-bound but not by circulating TNFalpha.
Volume: 19
Issue: 5
Pages: 725-37
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Publication
22067324 | J:181649
First Author: Jiao P
Year: 2012
Journal: Endocrinology
Title: Constitutive activation of IKKβ in adipose tissue prevents diet-induced obesity in mice.
Volume: 153
Issue: 1
Pages: 154-65
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Publication
22915098 | J:187707
First Author: Lattke M
Year: 2012
Journal: J Neurosci
Title: Nuclear factor κB activation impairs ependymal ciliogenesis and links neuroinflammation to hydrocephalus formation.
Volume: 32
Issue: 34
Pages: 11511-23
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Publication
23665348 | J:197438
First Author: Miyazaki D
Year: 2013
Journal: Am J Pathol
Title: Pharmacologic inhibition of IκB kinase activates immediate hypersensitivity reactions in mice.
Volume: 183
Issue: 1
Pages: 96-107
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Publication
20600852 | J:187567
First Author: Kim JE
Year: 2010
Journal: Cell Signal
Title: Suppression of NF-kappaB signaling by KEAP1 regulation of IKKbeta activity through autophagic degradation and inhibition of phosphorylation.
Volume: 22
Issue: 11
Pages: 1645-54
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Publication
11694538 | J:73695
First Author: Huber MA
Year: 2002
Journal: J Biol Chem
Title: The IKK-2/Ikappa Balpha /NF-kappa B pathway plays a key role in the regulation of CCR3 and eotaxin-1 in fibroblasts. A critical link to dermatitis in Ikappa Balpha -deficient mice.
Volume: 277
Issue: 2
Pages: 1268-75
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Publication
10373503 | J:55890
First Author: Zandi E
Year: 1999
Journal: Mol Cell Biol
Title: Bridging the gap: composition, regulation, and physiological function of the IkappaB kinase complex.
Volume: 19
Issue: 7
Pages: 4547-51
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Publication
16966325 | J:117584
First Author: Chen F
Year: 2006
Journal: J Biol Chem
Title: Loss of Ikkbeta promotes migration and proliferation of mouse embryo fibroblast cells.
Volume: 281
Issue: 48
Pages: 37142-9
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Publication
17525799 | J:122185
First Author: Baumann B
Year: 2007
Journal: J Clin Invest
Title: Constitutive IKK2 activation in acinar cells is sufficient to induce pancreatitis in vivo.
Volume: 117
Issue: 6
Pages: 1502-13
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Publication
11777949 | J:131003
First Author: Ren H
Year: 2002
Journal: J Immunol
Title: I-kappa B kinase beta is critical for B cell proliferation and antibody response.
Volume: 168
Issue: 2
Pages: 577-87
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Publication
18490760 | J:136345
First Author: Dan HC
Year: 2008
Journal: J Immunol
Title: Differential involvement of IkappaB kinases alpha and beta in cytokine- and insulin-induced mammalian target of rapamycin activation determined by Akt.
Volume: 180
Issue: 11
Pages: 7582-9
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Publication
18573490 | J:138018
First Author: Kim MH
Year: 2008
Journal: Biochem Pharmacol
Title: Novel iminobenzoxathiolone compound inhibits nuclear factor-kappaB activation targeting inhibitory kappaB kinase beta and down-regulating interleukin-1beta expression in lipopolysaccharide-activated macrophages.
Volume: 76
Issue: 3
Pages: 373-81
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Publication
19959994 | J:157473
First Author: Criollo A
Year: 2010
Journal: EMBO J
Title: The IKK complex contributes to the induction of autophagy.
Volume: 29
Issue: 3
Pages: 619-31
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Publication
22750522 | J:197510
First Author: Oeckl P
Year: 2012
Journal: Neurobiol Dis
Title: Astrocyte-specific IKK2 activation in mice is sufficient to induce neuroinflammation but does not increase susceptibility to MPTP.
Volume: 48
Issue: 3
Pages: 481-7
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Publication
24911653 | J:215318
First Author: Zhang J
Year: 2014
Journal: Biochem J
Title: An unexpected twist to the activation of IKKβ: TAK1 primes IKKβ for activation by autophosphorylation.
Volume: 461
Issue: 3
Pages: 531-7
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Publication
19962981 | J:309131
First Author: Shibata W
Year: 2010
Journal: Gastroenterology
Title: Conditional deletion of IkappaB-kinase-beta accelerates helicobacter-dependent gastric apoptosis, proliferation, and preneoplasia.
Volume: 138
Issue: 3
Pages: 1022-34.e1-10
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Publication
25358444 | J:319109
 
First Author: Liu C
Year: 2014
Journal: Part Fibre Toxicol
Title: Central IKKβ inhibition prevents air pollution mediated peripheral inflammation and exaggeration of type II diabetes.
Volume: 11
Pages: 53
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Publication
28377875 | J:318449
First Author: Douglass JD
Year: 2017
Journal: Mol Metab
Title: Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation.
Volume: 6
Issue: 4
Pages: 366-373
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Publication
36688823 | J:338758
First Author: Schnöder L
Year: 2023
Journal: FASEB J
Title: Deficiency of IKKβ in neurons ameliorates Alzheimer's disease pathology in APP- and tau-transgenic mice.
Volume: 37
Issue: 2
Pages: e22778
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GXD Expression
GXD Expression
     
Probe: MGI:2669235
Assay Type: Northern blot
Annotation Date: 2003-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2669238
Age: embryonic day 7.0
Specimen Label: 7-day
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:2669235
Assay Type: Northern blot
Annotation Date: 2003-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2669238
Age: embryonic day 11.0
Specimen Label: 11-day
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:2669235
Assay Type: Northern blot
Annotation Date: 2003-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2669238
Age: embryonic day 15.0
Specimen Label: 15-day
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:2669235
Assay Type: Northern blot
Annotation Date: 2003-08-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2669238
Age: embryonic day 17.0
Specimen Label: 17-day
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6108133
Assay Type: Western blot
Annotation Date: 2018-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557726
Stage: TS26
Assay Id: MGI:6108158
Age: embryonic day 18.0
Specimen Label: -/-
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6108133
Assay Type: Western blot
Annotation Date: 2018-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557726
Stage: TS26
Assay Id: MGI:6108158
Age: embryonic day 18.0
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6108133
Assay Type: Western blot
Annotation Date: 2018-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557726
Stage: TS26
Assay Id: MGI:6108158
Age: embryonic day 18.0
Specimen Label: +/-
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6108133
Assay Type: Western blot
Annotation Date: 2018-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557726
Stage: TS26
Assay Id: MGI:6108158
Age: embryonic day 18.0
Specimen Label: -/-
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:6108133
Assay Type: Western blot
Annotation Date: 2018-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557726
Stage: TS26
Assay Id: MGI:6108158
Age: embryonic day 18.0
Specimen Label: +/-
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6108133
Assay Type: Western blot
Annotation Date: 2018-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557726
Stage: TS26
Assay Id: MGI:6108158
Age: embryonic day 18.0
Specimen Label: +/-
Detected: true
Specimen Num: 6
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•
GXD Expression
GXD Expression
     
Probe: MGI:6108133
Assay Type: Western blot
Annotation Date: 2018-01-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3557726
Stage: TS26
Assay Id: MGI:6108158
Age: embryonic day 18.0
Specimen Label: +/+
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
   
Probe: MGI:7377716
Assay Type: RT-PCR
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:7377721
Age: embryonic day 17.5
Image: 2
Specimen Label: Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7377716
Assay Type: RT-PCR
Annotation Date: 2022-10-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610525
Stage: TS25
Assay Id: MGI:7377721
Age: embryonic day 17.5
Image: 2
Specimen Label: IKK
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4416098
Assay Type: RNA in situ
Annotation Date: 2024-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7614699
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2769723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4416098
Assay Type: RNA in situ
Annotation Date: 2024-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7614699
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2853323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
   
Probe: MGI:4416098
Assay Type: RNA in situ
Annotation Date: 2024-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7614699
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2845723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1795023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1869223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2854023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2762123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1797223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:1832123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:4416098
Assay Type: RNA in situ
Annotation Date: 2024-03-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7614699
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2851823
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2760523
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2852723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2874723
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Male
Emaps: EMAPS:2850023
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5115
Specimen Label: GUDMAP:5115
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:5000602
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Present
Sex: Female
Emaps: EMAPS:1796223
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5541162
Age: embryonic day 15.5
Image: GUDMAP:5114
Specimen Label: GUDMAP:5114
Detected: true
Specimen Num: 1
•
•
•
•
•
Publication
17322906 | J:120808
First Author: Zaph C
Year: 2007
Journal: Nature
Title: Epithelial-cell-intrinsic IKK-beta expression regulates intestinal immune homeostasis.
Volume: 446
Issue: 7135
Pages: 552-6
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•
•
•
•
Publication
23011799 | J:190332
First Author: Miller M
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: ORMDL3 is an inducible lung epithelial gene regulating metalloproteases, chemokines, OAS, and ATF6.
Volume: 109
Issue: 41
Pages: 16648-53
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Publication
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First Author: Karim ZA
Year: 2013
Journal: Blood
Title: IκB kinase phosphorylation of SNAP-23 controls platelet secretion.
Volume: 121
Issue: 22
Pages: 4567-74
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Publication
16887827 | J:112268
First Author: Baxter FO
Year: 2006
Journal: Development
Title: IKKbeta/2 induces TWEAK and apoptosis in mammary epithelial cells.
Volume: 133
Issue: 17
Pages: 3485-94
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Publication
27387502 | J:236157
First Author: Mei ZZ
Year: 2016
Journal: J Biol Chem
Title: Kelch-like Protein 21 (KLHL21) Targets IκB Kinase-β to Regulate Nuclear Factor κ-Light Chain Enhancer of Activated B Cells (NF-κB) Signaling Negatively.
Volume: 291
Issue: 35
Pages: 18176-89
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Publication
9520401 | J:54768
First Author: Nakano H
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Differential regulation of IkappaB kinase alpha and beta by two upstream kinases, NF-kappaB-inducing kinase and mitogen-activated protein kinase/ERK kinase kinase-1.
Volume: 95
Issue: 7
Pages: 3537-42
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Publication
25326420 | J:216669
First Author: Ren J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: IKKβ is an IRF5 kinase that instigates inflammation.
Volume: 111
Issue: 49
Pages: 17438-43
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Publication
20220849 | J:157973
First Author: Ammirante M
Year: 2010
Journal: Nature
Title: B-cell-derived lymphotoxin promotes castration-resistant prostate cancer.
Volume: 464
Issue: 7286
Pages: 302-5
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•
•
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Publication
16775250 | J:133761
First Author: Rasoulpour RJ
Year: 2006
Journal: J Androl
Title: The Sycp1-Cre transgenic mouse and male germ cell inhibition of NF-kappa b.
Volume: 27
Issue: 6
Pages: 729-33
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•
•
•
Publication
20007767 | J:156490
First Author: Herrero L
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Inflammation and adipose tissue macrophages in lipodystrophic mice.
Volume: 107
Issue: 1
Pages: 240-5
•
•
•
•
•
Publication
17570221 | J:128311
First Author: Geisler F
Year: 2007
Journal: Gastroenterology
Title: Genetic inactivation of RelA/p65 sensitizes adult mouse hepatocytes to TNF-induced apoptosis in vivo and in vitro.
Volume: 132
Issue: 7
Pages: 2489-503
•
•
•
•
•
Publication
26102347 | J:237886
First Author: Zhang J
Year: 2015
Journal: PLoS One
Title: Loss of IKKβ but Not NF-κB p65 Skews Differentiation towards Myeloid over Erythroid Commitment and Increases Myeloid Progenitor Self-Renewal and Functional Long-Term Hematopoietic Stem Cells.
Volume: 10
Issue: 6
Pages: e0130441
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•
Publication
15070758 | J:292666
First Author: Schmidt-Supprian M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-kappaB activation.
Volume: 101
Issue: 13
Pages: 4566-71
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•
•
•
•
Publication
15265889 | J:92037
First Author: Schmidt-Supprian M
Year: 2004
Journal: J Immunol
Title: I kappa B kinase 2 deficiency in T cells leads to defects in priming, B cell help, germinal center reactions, and homeostatic expansion.
Volume: 173
Issue: 3
Pages: 1612-9
•
•
•
•
•
Publication
14499113 | J:85810
First Author: Schmidt-Supprian M
Year: 2003
Journal: Immunity
Title: Mature T cells depend on signaling through the IKK complex.
Volume: 19
Issue: 3
Pages: 377-89
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•
•
•
•
Publication
27582100 | J:281395
First Author: Guo L
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Lymphocyte-specific deletion of IKK2 or NEMO mediates an increase in intrarenal Th17 cells and accelerates renal damage in an ischemia-reperfusion injury mouse model.
Volume: 311
Issue: 5
Pages: F1005-F1014
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Publication
30285578 | J:289926
First Author: Guo L
Year: 2019
Journal: FASEB J
Title: T-lymphocyte-specific knockout of IKK-2 or NEMO induces Th17 cells in an experimental nephrotoxic nephritis mouse model.
Volume: 33
Issue: 2
Pages: 2359-2371
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•
•
•
•
Publication
21983962 | J:268782
First Author: Takeda Y
Year: 2011
Journal: Nature
Title: Macrophage skewing by Phd2 haplodeficiency prevents ischaemia by inducing arteriogenesis.
Volume: 479
Issue: 7371
Pages: 122-6
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•
•
Publication
17204585 | J:136649
First Author: Mathew B
Year: 2007
Journal: Am J Respir Cell Mol Biol
Title: Inhibitory kappaB kinase 2 activates airway epithelial cells to stimulate bone marrow macrophages.
Volume: 36
Issue: 5
Pages: 562-72
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•
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•
Publication
31552024 | J:281376
 
First Author: Mackos AR
Year: 2019
Journal: Front Immunol
Title: Mice Deficient in Epithelial or Myeloid Cell Iκκβ Have Distinct Colonic Microbiomes and Increased Resistance to Citrobacter rodentium Infection.
Volume: 10
Pages: 2062
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Publication
24667561 | J:214148
First Author: Bonnegarde-Bernard A
Year: 2014
Journal: PLoS One
Title: Routes of allergic sensitization and myeloid cell IKKβ differentially regulate antibody responses and allergic airway inflammation in male and female mice.
Volume: 9
Issue: 3
Pages: e92307
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Publication
18819987 | J:266691
First Author: Cho IH
Year: 2008
Journal: Brain
Title: Role of microglial IKKbeta in kainic acid-induced hippocampal neuronal cell death.
Volume: 131
Issue: Pt 11
Pages: 3019-33
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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