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Search results 501 to 600 out of 649 for Ikbkb

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Type Details Score
Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
31826938 | J:282971
First Author: Wu H
Year: 2020
Journal: J Immunol
Title: IKIP Negatively Regulates NF-κB Activation and Inflammation through Inhibition of IKKα/β Phosphorylation.
Volume: 204
Issue: 2
Pages: 418-427
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Publication
- | J:287716
       
First Author: Korea Mouse Phenotyping Center
Year: 2020
Title: International Mouse Strain Resource (IMSR) KMPC load file
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Allele
Ikbip<+> | MGI:4366835
 
Name: IKBKB interacting protein; wild type
Allele Type: Not Specified
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Protein Coding Gene
MGP_CAROLIEiJ_G0015724 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0017643 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017622 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017580 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017585 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914704 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018042 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0016973 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017377 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017483 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017557 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017506 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018079 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0016754 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017032 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031361 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016542 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
15389287 | J:114118
First Author: Hofer-Warbinek R
Year: 2004
Journal: Cell Death Differ
Title: A highly conserved proapoptotic gene, IKIP, located next to the APAF1 gene locus, is regulated by p53.
Volume: 11
Issue: 12
Pages: 1317-25
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_03
Specimen Label: euxassay_005339_03
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_04
Specimen Label: euxassay_005339_04
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_05
Specimen Label: euxassay_005339_05
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_06
Specimen Label: euxassay_005339_06
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_07
Specimen Label: euxassay_005339_07
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_08
Specimen Label: euxassay_005339_08
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_09
Specimen Label: euxassay_005339_09
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_15
Specimen Label: euxassay_005339_15
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_16
Specimen Label: euxassay_005339_16
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_17
Specimen Label: euxassay_005339_17
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_18
Specimen Label: euxassay_005339_18
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1829023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_19
Specimen Label: euxassay_005339_19
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_03
Note: periosteum
Specimen Label: euxassay_005339_03
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_04
Note: periosteum
Specimen Label: euxassay_005339_04
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_05
Note: periosteum
Specimen Label: euxassay_005339_05
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_16
Note: periosteum
Specimen Label: euxassay_005339_16
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_17
Note: periosteum
Specimen Label: euxassay_005339_17
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_18
Note: periosteum
Specimen Label: euxassay_005339_18
Detected: true
Specimen Num: 11
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GXD Expression
GXD Expression
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_19
Note: periosteum
Specimen Label: euxassay_005339_19
Detected: true
Specimen Num: 12
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GXD Expression
GXD Expression
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1801023
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_20
Note: periosteum
Specimen Label: euxassay_005339_20
Detected: true
Specimen Num: 13
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_03
Specimen Label: euxassay_005339_03
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_04
Specimen Label: euxassay_005339_04
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_05
Specimen Label: euxassay_005339_05
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_06
Specimen Label: euxassay_005339_06
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_07
Specimen Label: euxassay_005339_07
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_08
Specimen Label: euxassay_005339_08
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_09
Specimen Label: euxassay_005339_09
Detected: true
Specimen Num: 7
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_15
Specimen Label: euxassay_005339_15
Detected: true
Specimen Num: 8
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_16
Specimen Label: euxassay_005339_16
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_17
Specimen Label: euxassay_005339_17
Detected: true
Specimen Num: 10
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GXD Expression
GXD Expression
 
Probe: MGI:920678
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1763923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4825553
Age: embryonic day 14.5
Image: euxassay_005339_18
Specimen Label: euxassay_005339_18
Detected: true
Specimen Num: 11
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Allele
Ikbip<em1Hwl> | MGI:6423281
Name: IKBKB interacting protein; endonuclease-mediated mutation 1, Han-Woong Lee
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Ikbip<em1Bcgen> | MGI:6712194
Name: IKBKB interacting protein; endonuclease-mediated mutation 1, Biocytogen LLC
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready
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Allele
Ikbip<em3Gpt> | MGI:7300700
Name: IKBKB interacting protein; endonuclease-mediated mutation 3, GemPharmatech Co., Ltd
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6424040 | C57BL/6NTac-Ikbip<em1Hwl>/Krb
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Strain
MGI:6768096 | C57BL/6JGpt-Ikbip<em3Gpt>/Gpt
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Protein
O88351
Organism: Mus musculus/domesticus
Length: 757  
Fragment?: false
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GO Term
GO:0008384 | IkappaB kinase activity
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Genotype
Genotype
Symbol: Ikbip/Ikbip Lyz2/Lyz2<+>
Background: involves: 129P2/OlaHsd
Zygosity: cn
Has Mutant Allele: true
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Allele
Ikbkb<em1Macc> | MGI:6444679
Name: inhibitor of kappaB kinase beta; endonuclease-mediated mutation 1, Matthew C Cook
Allele Type: Endonuclease-mediated
Attribute String: Constitutively active, Humanized sequence
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Allele
Tg(Alb1-IKBKB*S177E*S181E)1Mka | MGI:5824105
Name: transgene insertion 1, Michael Karin
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Ikbkb/Ikbkb
Background: involves: C57BL/6NCrl
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Ikbkb/Ikbkb<+>
Background: involves: C57BL/6NCrl
Zygosity: ht
Has Mutant Allele: true
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DO Term
DOID:0111960 | immunodeficiency 15A
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Allele
Ikbkb<em2Smoc> | MGI:7278689
Name: inhibitor of kappaB kinase beta; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
21474453 | -
First Author: Benfield CT
Year: 2011
Journal: J Biol Chem
Title: Mapping the IkappaB kinase beta (IKKbeta)-binding interface of the B14 protein, a vaccinia virus inhibitor of IKKbeta-mediated activation of nuclear factor kappaB.
Volume: 286
Issue: 23
Pages: 20727-35
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Protein Domain
IPR011212 | Poxvirus_B14/B22/C16
Type: Family
Description: This is a family of conserved poxvirus proteins related to Protein B14 and Protein B22/C16 from Vaccinia virus. B14 contributes to virulence by binding to the host IKBKB subunit of the IKK complex and preventing host NF-kappa-B activation in response to pro-inflammatory stimuli such as TNF-alpha or IL1B. Mechanistically, it sterically hinders the direct contact between the kinase domains of IKBKB in the IKK complex containing IKBKB, CHUK/IKKA and NEMO [, , ].
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DO Term
DOID:0111959 | immunodeficiency 15B
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Allele
Gt(ROSA)26Sor<tm4(Ikbkb)Rsky> | MGI:3687199
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 4, Klaus Rajewsky
Allele Type: Targeted
Attribute String: Conditional ready, Constitutively active, Inserted expressed sequence, Reporter
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Publication
23792959 | -
First Author: Liu S
Year: 2013
Journal: J Biol Chem
Title: Crystal structure of a human IκB kinase β asymmetric dimer.
Volume: 288
Issue: 31
Pages: 22758-67
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Publication
23776406 | -
First Author: Polley S
Year: 2013
Journal: PLoS Biol
Title: A structural basis for IκB kinase 2 activation via oligomerization-dependent trans auto-phosphorylation.
Volume: 11
Issue: 6
Pages: e1001581
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Protein Domain
IPR041185 | IKBKB_SDD
Type: Domain
Description: This is the C-terminal scaffold dimerization domain (SDD) found in inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB) []. IKBKB is one of the core component of IKB kinases (IKK), which is an enzyme that quickly becomes active in response to diverse stresses. The SDD consists primarily of two long α-helices []. This domain can also be found in inhibitor of nuclear factor kappa-B kinase subunit alpha (IKKA).
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Protein Domain
IPR046375 | IKBKB_SDD_sf
Type: Homologous_superfamily
Description: This superfamily represents the C-terminal scaffold dimerization domain (SDD) found in inhibitor of nuclear factor kappa-B kinase subunit beta (IKBKB) []. IKBKB is one of the core component of IKB kinases (IKK), which is an enzyme that quickly becomes active in response to diverse stresses. The SDD consists primarily of two long α-helices []. This domain can also be found in inhibitor of nuclear factor kappa-B kinase subunit alpha (IKKA).
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Allele
Tg(KRT5-IKBKB)1Armz | MGI:4456367
Name: transgene insertion 1, Angel Ramirez
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:3773070 | B6.Cg-Gt(ROSA)26Sor<tm4(Ikbkb)Rsky>/J
Attribute String: congenic, targeted mutation, mutant strain
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Allele
Ikbkb<tm1Ver> | MGI:2386269
Name: inhibitor of kappaB kinase beta; targeted mutation 1, Inder M Verma
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Tg(KRT5-IKBKB)2Armz | MGI:4456368
Name: transgene insertion 2, Angel Ramirez
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Genotype
Genotype
Symbol: Ikbkb/Ikbkb
Background: involves: 129S4/SvJae * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Protein
A0AUV3
Organism: Mus musculus/domesticus
Length: 306  
Fragment?: true
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Publication
29748387 | -
First Author: Tang Q
Year: 2018
Journal: J Biol Chem
Title: Mechanism of vaccinia viral protein B14-mediated inhibition of IκB kinase β activation.
Volume: 293
Issue: 26
Pages: 10344-10352
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Strain
MGI:5708159 | B6D2-Tg(KRT5-IKBKB)1Armz/Cnbc
Attribute String: mutant stock, transgenic
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Publication
30425986 | J:290021
 
First Author: Nakagawa MM
Year: 2018
Journal: Front Cell Dev Biol
Title: Constitutive Activation of NF-κB Pathway in Hematopoietic Stem Cells Causes Loss of Quiescence and Deregulated Transcription Factor Networks.
Volume: 6
Pages: 143
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Publication
26896735 | J:335357
First Author: Tétreault MP
Year: 2016
Journal: Gastroenterology
Title: Esophageal Expression of Active IκB Kinase-β in Mice Up-Regulates Tumor Necrosis Factor and Granulocyte-Macrophage Colony-Stimulating Factor, Promoting Inflammation and Angiogenesis.
Volume: 150
Issue: 7
Pages: 1609-1619.e11
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Genotype
Genotype
Symbol: Cd19/Cd19<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(KRT5-IKBKB)1Armz/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(KRT5-IKBKB)2Armz/?
Background: involves: C57BL/6 * DBA/2
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ighg1/Ighg1<+>
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Twist2/Twist2<+>
Background: involves: 129X1/SvJ * C57BL/6J
Zygosity: cn
Has Mutant Allele: true
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Publication
27043411 | J:259593
First Author: Xing Y
Year: 2016
Journal: Nat Immunol
Title: Late stages of T cell maturation in the thymus involve NF-κB and tonic type I interferon signaling.
Volume: 17
Issue: 5
Pages: 565-73
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Publication
32661025 | J:294220
First Author: Lei Z
Year: 2020
Journal: J Neurosci
Title: NF-κB Activation Accounts for the Cytoprotective Effects of PERK Activation on Oligodendrocytes during EAE.
Volume: 40
Issue: 33
Pages: 6444-6456
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