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Search results 701 to 800 out of 899 for Abca1

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Type Details Score
ncRNA Gene
MGP_BALBcJ_G0006390 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_C3HHeJ_G0006340 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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lncRNA Gene
MGI_C57BL6J_2140270 | -
Type: lncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_C57BL6NJ_G0006556 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CASTEiJ_G0006274 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_CBAJ_G0006323 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_DBA2J_G0006345 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_FVBNJ_G0006367 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_LPJ_G0006426 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_NODShiLtJ_G0006354 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_NZOHlLtJ_G0006560 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_PWKPhJ_G0006210 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_WSBEiJ_G0006319 | -
Type: ncRNA_gene
Organism: mouse, laboratory
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ncRNA Gene
MGP_PahariEiJ_G0006163 | -
Type: ncRNA_gene
Organism: Mus pahari
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ncRNA Gene
MGP_SPRETEiJ_G0006123 | -
Type: ncRNA_gene
Organism: Mus spretus
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Genotype
Genotype
Symbol: Tg(ALB-cre,CMV-rtTA)#Wcyy/? Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy/?
Background: involves: ICR
Zygosity: cn
Has Mutant Allele: true
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Allele
Abca1<em1Smoc> | MGI:7288019
Name: ATP-binding cassette, sub-family A member 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, No functional change
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Publication
17991739 | -
First Author: Yan D
Year: 2008
Journal: J Biol Chem
Title: OSBP-related protein 8 (ORP8) suppresses ABCA1 expression and cholesterol efflux from macrophages.
Volume: 283
Issue: 1
Pages: 332-40
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Publication
11355874 | -
First Author: Tanaka AR
Year: 2001
Journal: Biochem Biophys Res Commun
Title: Human ABCA1 contains a large amino-terminal extracellular domain homologous to an epitope of Sjögren's Syndrome.
Volume: 283
Issue: 5
Pages: 1019-25
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Allele
Abca1<tm1Jp> | MGI:3577723
Name: ATP-binding cassette, sub-family A member 1; targeted mutation 1, John S Parks
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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Allele
Abca1<tm1.1Jp> | MGI:3577725
Name: ATP-binding cassette, sub-family A member 1; targeted mutation 1.1, John S Parks
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Abca1<tm1Blt> | MGI:3525100
Name: ATP-binding cassette, sub-family A member 1; targeted mutation 1, Horst Bluethmann
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Abca1<tm1Wpfl> | MGI:1935193
Name: ATP-binding cassette, sub-family A member 1; targeted mutation 1, Wai-Ping Fung-Leung
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Abca1<tm1Jdm> | MGI:1935192
Name: ATP-binding cassette, sub-family A member 1; targeted mutation 1, John D McNeish
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
32482798 | J:292021
 
First Author: Yang M
Year: 2020
Journal: Mol Cell Biol
Title: Human Insulin Growth Factor 2 mRNA Binding Protein 2 Increases MicroRNA 33a/b Inhibition of Liver ABCA1 Expression and Alters Low-Density Apolipoprotein Levels in Mice.
Volume: 40
Issue: 16
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Transgene
MGI:3510913 | Tg(CMV-EGFP,Rnu6-siAbca1)#Wcyy
Type: transgene
Organism: mouse, laboratory
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Genotype
Genotype
Symbol: Abca1/Abca1
Background: DBA/1LacJ-Abca1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Abca1/Abca1
Background: involves: 129P2/OlaHsd * C57BL/6J
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Abca1/Abca1
Background: C57BL/6-Abca1
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Abca1/Abca1 Speer6-ps1/Speer6-ps1<+>
Background: involves: 129S6/SvEvTac * B6.Cg-Tg(Alb-cre)21Mgn/J
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Abca1/Abca1
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: hm
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Abca1/Abca1 Tg(APOA1)427Bres/?
Background: involves: 129X1/SvJ * C57BL/6J * CBA/J
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Abca1/Abca1<+> Tg(APOA1)427Bres/?
Background: involves: 129X1/SvJ * C57BL/6J * CBA/J
Zygosity: cx
Has Mutant Allele: true
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DO Term
DOID:1388 | Tangier disease
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Allele
Tg(APOE-ABCA1)30Ssf | MGI:3696684
Name: transgene insertion 30, Silvia Santamarina-Fojo
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-Abca1)DHol | MGI:7614750
Name: transgene insertion D, David M Holtzman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Tg(Prnp-Abca1)EHol | MGI:3800823
Name: transgene insertion E, David M Holtzman
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:5140313 | C57BL/6N-Tg(APOE-ABCA1)30Ssf
Attribute String: coisogenic, mutant strain, transgenic
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Strain
MGI:4422212 | C57BL/6-Tg(APOE-ABCA1)30Ssf/Mmmh
Attribute String: transgenic, mutant strain, coisogenic
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Strain
MGI:3801181 | B6.Cg-Tg(Prnp-Abca1)EHol/J
Attribute String: transgenic, congenic
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Genotype
Genotype
Symbol: Tg(Prnp-Abca1)EHol/?
Background: involves: C57BL/6 * CBA
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APOE-ABCA1)30Ssf/?
Background: C57BL/6N-Tg(APOE-ABCA1)30Ssf
Zygosity: ot
Has Mutant Allele: true
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Publication
37995685 | J:346146
First Author: Litvinchuk A
Year: 2024
Journal: Neuron
Title: Amelioration of Tau and ApoE4-linked glial lipid accumulation and neurodegeneration with an LXR agonist.
Volume: 112
Issue: 3
Pages: 384-403.e8
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Publication
15509524 | J:93624
First Author: Chang HS
Year: 2004
Journal: Am J Pathol
Title: Using siRNA technique to generate transgenic animals with spatiotemporal and conditional gene knockdown.
Volume: 165
Issue: 5
Pages: 1535-41
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Allele
Tg(ABCA1)1Hgc | MGI:3832216
Name: transgene insertion 1, Human Genome Center
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Strain
MGI:3832217 | FVB-Tg(ABCA1)1Hgc/Mmmh
Attribute String: coisogenic, transgenic
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Genotype
Genotype
Symbol: Apoe/Apoe Tg(Prnp-Abca1)EHol/?
Background: involves: 129P2/OlaHsd * C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(APPV717F)109Ili/? Tg(Prnp-Abca1)EHol/?
Background: involves: C57BL/6 * CBA
Zygosity: cx
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(ABCA1)1Hgc/?
Background: involves: FVB
Zygosity: ot
Has Mutant Allele: true
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Publication
21554545 | J:190796
First Author: Nagao K
Year: 2011
Journal: FEBS J
Title: Function and regulation of ABCA1--membrane meso-domain organization and reorganization.
Volume: 278
Issue: 18
Pages: 3190-203
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Publication
27148853 | J:233832
First Author: Ikhlef S
Year: 2016
Journal: FEBS Lett
Title: Paraoxonase 1-treated oxLDL promotes cholesterol efflux from macrophages by stimulating the PPARγ-LXRα-ABCA1 pathway.
Volume: 590
Issue: 11
Pages: 1614-29
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Publication
36291054 | J:330958
 
First Author: Cassim Bawa FN
Year: 2022
Journal: Cells
Title: Retinoic Acid Receptor Alpha (RARα) in Macrophages Protects from Diet-Induced Atherosclerosis in Mice.
Volume: 11
Issue: 20
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Publication
20466885 | J:160971
First Author: Rayner KJ
Year: 2010
Journal: Science
Title: MiR-33 contributes to the regulation of cholesterol homeostasis.
Volume: 328
Issue: 5985
Pages: 1570-3
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Publication
27460411 | J:241166
 
First Author: Aryal B
Year: 2016
Journal: Nat Commun
Title: ANGPTL4 deficiency in haematopoietic cells promotes monocyte expansion and atherosclerosis progression.
Volume: 7
Pages: 12313
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Publication
33458623 | J:322010
First Author: Wilkinson H
Year: 2021
Journal: iScience
Title: PAR-1 signaling on macrophages is required for effective in vivo delayed-type hypersensitivity responses.
Volume: 24
Issue: 1
Pages: 101981
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Publication
33299105 | J:301483
First Author: Nagai N
Year: 2020
Journal: Commun Biol
Title: Renin-angiotensin system impairs macrophage lipid metabolism to promote age-related macular degeneration in mouse models.
Volume: 3
Issue: 1
Pages: 767
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Publication
25301063 | J:260487
First Author: Valenza M
Year: 2015
Journal: Cell Death Differ
Title: Disruption of astrocyte-neuron cholesterol cross talk affects neuronal function in Huntington's disease.
Volume: 22
Issue: 4
Pages: 690-702
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Publication
20855588 | J:165420
First Author: Horie T
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: MicroRNA-33 encoded by an intron of sterol regulatory element-binding protein 2 (Srebp2) regulates HDL in vivo.
Volume: 107
Issue: 40
Pages: 17321-6
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Publication
31141688 | J:278830
First Author: Vivas O
Year: 2019
Journal: Cell Rep
Title: Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P2 That Regulates Neuronal Excitability.
Volume: 27
Issue: 9
Pages: 2636-2648.e4
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Publication
30580964 | J:311833
First Author: Moon SH
Year: 2019
Journal: Cell
Title: p53 Represses the Mevalonate Pathway to Mediate Tumor Suppression.
Volume: 176
Issue: 3
Pages: 564-580.e19
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Publication
34341345 | J:323035
First Author: Wright MB
Year: 2021
Journal: Nat Commun
Title: Compounds targeting OSBPL7 increase ABCA1-dependent cholesterol efflux preserving kidney function in two models of kidney disease.
Volume: 12
Issue: 1
Pages: 4662
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Publication
20466882 | J:160972
First Author: Najafi-Shoushtari SH
Year: 2010
Journal: Science
Title: MicroRNA-33 and the SREBP host genes cooperate to control cholesterol homeostasis.
Volume: 328
Issue: 5985
Pages: 1566-9
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Publication
14580333 | J:87052
First Author: Castrillo A
Year: 2003
Journal: Mol Cell
Title: Crosstalk between LXR and toll-like receptor signaling mediates bacterial and viral antagonism of cholesterol metabolism.
Volume: 12
Issue: 4
Pages: 805-16
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Publication
20566875 | J:162069
First Author: Marquart TJ
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: miR-33 links SREBP-2 induction to repression of sterol transporters.
Volume: 107
Issue: 27
Pages: 12228-32
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Publication
25035344 | J:227173
First Author: Cao Q
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Histone deacetylase 9 represses cholesterol efflux and alternatively activated macrophages in atherosclerosis development.
Volume: 34
Issue: 9
Pages: 1871-9
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Publication
27297104 | J:236100
First Author: Okoro EU
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Akt isoform-dependent regulation of ATP-Binding cassette A1 expression by apolipoprotein E.
Volume: 477
Issue: 1
Pages: 123-8
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Publication
29144234 | J:255005
   
First Author: Xian X
Year: 2017
Journal: Elife
Title: LRP1 integrates murine macrophage cholesterol homeostasis and inflammatory responses in atherosclerosis.
Volume: 6
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Publication
31799433 | J:289136
 
First Author: Belorusova AY
Year: 2019
Journal: Commun Biol
Title: Structural analysis identifies an escape route from the adverse lipogenic effects of liver X receptor ligands.
Volume: 2
Pages: 431
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Publication
34854376 | J:344007
   
First Author: Wilfahrt D
Year: 2021
Journal: Elife
Title: Histone deacetylase 3 represses cholesterol efflux during CD4(+) T-cell activation.
Volume: 10
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Publication
32687853 | J:302471
First Author: Ray AG
Year: 2020
Journal: J Mol Biol
Title: Novel Mechanism of Cholesterol Transport by ABCA5 in Macrophages and Its Role in Dyslipidemia.
Volume: 432
Issue: 17
Pages: 4922-4941
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Publication
12917409 | J:207821
First Author: Wang N
Year: 2003
Journal: J Biol Chem
Title: ATP-binding cassette transporter A7 (ABCA7) binds apolipoprotein A-I and mediates cellular phospholipid but not cholesterol efflux.
Volume: 278
Issue: 44
Pages: 42906-12
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Publication
15550377 | J:96865
First Author: Kim WS
Year: 2005
Journal: J Biol Chem
Title: Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.
Volume: 280
Issue: 5
Pages: 3989-95
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Publication
12706902 | J:83207
 
First Author: Barros SA
Year: 2003
Journal: Gene
Title: Molecular structure and characterization of a novel murine ABC transporter, Abca13.
Volume: 307
Pages: 191-200
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Publication
25347070 | J:223099
First Author: van Kampen E
Year: 2014
Journal: PLoS One
Title: Orp8 deficiency in bone marrow-derived cells reduces atherosclerotic lesion progression in LDL receptor knockout mice.
Volume: 9
Issue: 10
Pages: e109024
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Publication
15173162 | J:121206
First Author: Davis HR Jr
Year: 2004
Journal: J Biol Chem
Title: Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
Volume: 279
Issue: 32
Pages: 33586-92
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Publication
23719382 | J:198730
First Author: Fang L
Year: 2013
Journal: Nature
Title: Control of angiogenesis by AIBP-mediated cholesterol efflux.
Volume: 498
Issue: 7452
Pages: 118-22
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Publication
24871327 | J:317579
First Author: Iatan I
Year: 2014
Journal: Circ Cardiovasc Genet
Title: The WWOX gene modulates high-density lipoprotein and lipid metabolism.
Volume: 7
Issue: 4
Pages: 491-504
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Publication
31055081 | J:283443
First Author: Fanaee-Danesh E
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Astaxanthin exerts protective effects similar to bexarotene in Alzheimer's disease by modulating amyloid-beta and cholesterol homeostasis in blood-brain barrier endothelial cells.
Volume: 1865
Issue: 9
Pages: 2224-2245
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Publication
19416652 | J:148766
First Author: Li Z
Year: 2009
Journal: Biochim Biophys Acta
Title: Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol.
Volume: 1791
Issue: 4
Pages: 297-306
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Publication
28487312 | J:277018
First Author: De Giorgi M
Year: 2017
Journal: J Lipid Res
Title: Complete deletion of Cd39 is atheroprotective in apolipoprotein E-deficient mice.
Volume: 58
Issue: 7
Pages: 1292-1305
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Publication
20064973 | J:161502
First Author: Baker AD
Year: 2010
Journal: J Lipid Res
Title: Targeted PPAR{gamma} deficiency in alveolar macrophages disrupts surfactant catabolism.
Volume: 51
Issue: 6
Pages: 1325-31
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Publication
15919660 | J:100822
First Author: Valasek MA
Year: 2005
Journal: J Biol Chem
Title: Caveolin-1 is not required for murine intestinal cholesterol transport.
Volume: 280
Issue: 30
Pages: 28103-9
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Publication
19207582 | J:215883
First Author: Okada K
Year: 2009
Journal: Hepatol Res
Title: The alpha-glucosidase inhibitor acarbose prevents obesity and simple steatosis in sequestosome 1/A170/p62 deficient mice.
Volume: 39
Issue: 5
Pages: 490-500
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Publication
21138980 | J:278493
First Author: de Beer MC
Year: 2011
Journal: J Lipid Res
Title: ATP binding cassette G1-dependent cholesterol efflux during inflammation.
Volume: 52
Issue: 2
Pages: 345-53
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Publication
15831500 | J:100273
First Author: Gerin I
Year: 2005
Journal: J Biol Chem
Title: LXRbeta is required for adipocyte growth, glucose homeostasis, and beta cell function.
Volume: 280
Issue: 24
Pages: 23024-31
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Publication
32588196 | J:309960
First Author: Vlacil AK
Year: 2020
Journal: Basic Res Cardiol
Title: Deficiency of Nucleotide-binding oligomerization domain-containing proteins (NOD) 1 and 2 reduces atherosclerosis.
Volume: 115
Issue: 4
Pages: 47
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Publication
16823488 | J:111742
First Author: Cummins CL
Year: 2006
Journal: J Clin Invest
Title: Liver X receptors regulate adrenal cholesterol balance.
Volume: 116
Issue: 7
Pages: 1902-12
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Publication
23519695 | J:340671
First Author: Ramírez CM
Year: 2013
Journal: Circ Res
Title: Control of cholesterol metabolism and plasma high-density lipoprotein levels by microRNA-144.
Volume: 112
Issue: 12
Pages: 1592-601
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Publication
32861706 | J:296682
 
First Author: Ma L
Year: 2020
Journal: Cancer Lett
Title: 27-Hydroxycholesterol acts on myeloid immune cells to induce T cell dysfunction, promoting breast cancer progression.
Volume: 493
Pages: 266-283
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Publication
30153049 | J:285601
First Author: Huang Z
Year: 2019
Journal: FASEB J
Title: G protein pathway suppressor 2 (GPS2) links inflammation and cholesterol efflux by controlling lipopolysaccharide-induced ATP-binding cassette transporter A1 expression in macrophages.
Volume: 33
Issue: 2
Pages: 1631-1643
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Publication
27154724 | J:243983
First Author: Higashi Y
Year: 2016
Journal: Circulation
Title: Insulin-Like Growth Factor-1 Receptor Deficiency in Macrophages Accelerates Atherosclerosis and Induces an Unstable Plaque Phenotype in Apolipoprotein E-Deficient Mice.
Volume: 133
Issue: 23
Pages: 2263-78
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Publication
25926396 | J:325785
First Author: Paik J
Year: 2015
Journal: Comp Med
Title: Effects of murine norovirus on atherosclerosis in ldlr(-/-) mice depends on the timing of infection.
Volume: 65
Issue: 2
Pages: 114-22
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Publication
31803904 | J:282801
First Author: Salerno AG
Year: 2019
Journal: Biochem J
Title: Lack of mitochondrial NADP(H)-transhydrogenase expression in macrophages exacerbates atherosclerosis in hypercholesterolemic mice.
Volume: 476
Issue: 24
Pages: 3769-3789
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Publication
16199802 | J:106132
First Author: Ko KW
Year: 2005
Journal: J Lipid Res
Title: Endothelial lipase modulates HDL but has no effect on atherosclerosis development in apoE-/- and LDLR-/- mice.
Volume: 46
Issue: 12
Pages: 2586-94
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Publication
26253613 | J:252783
First Author: Daffu G
Year: 2015
Journal: Diabetes
Title: RAGE Suppresses ABCG1-Mediated Macrophage Cholesterol Efflux in Diabetes.
Volume: 64
Issue: 12
Pages: 4046-60
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Publication
17478758 | J:134908
First Author: Yan D
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Expression of human OSBP-related protein 1L in macrophages enhances atherosclerotic lesion development in LDL receptor-deficient mice.
Volume: 27
Issue: 7
Pages: 1618-24
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Publication
24466075 | J:225166
First Author: van Stijn CM
Year: 2014
Journal: PLoS One
Title: Adiponectin expression protects against angiotensin II-mediated inflammation and accelerated atherosclerosis.
Volume: 9
Issue: 1
Pages: e86404
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Publication
31852219 | J:304903
First Author: Cheng J
Year: 2020
Journal: Arterioscler Thromb Vasc Biol
Title: MicroRNA-144 Silencing Protects Against Atherosclerosis in Male, but Not Female Mice.
Volume: 40
Issue: 2
Pages: 412-425
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Publication
17846428 | J:125197
First Author: Terasaka N
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: High-density lipoprotein protects macrophages from oxidized low-density lipoprotein-induced apoptosis by promoting efflux of 7-ketocholesterol via ABCG1.
Volume: 104
Issue: 38
Pages: 15093-8
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Publication
17724261 | J:139843
First Author: Babaev VR
Year: 2007
Journal: Circulation
Title: Macrophage expression of peroxisome proliferator-activated receptor-alpha reduces atherosclerosis in low-density lipoprotein receptor-deficient mice.
Volume: 116
Issue: 12
Pages: 1404-12
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