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Search results 1 to 100 out of 117 for Wnk1

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Category: Publication
Type Details Score
Publication
First Author: Shekarabi M
Year: 2008
Journal: J Clin Invest
Title: Mutations in the nervous system--specific HSN2 exon of WNK1 cause hereditary sensory neuropathy type II.
Volume: 118
Issue: 7
Pages: 2496-505
Publication
First Author: Susa K
Year: 2014
Journal: Hum Mol Genet
Title: Impaired degradation of WNK1 and WNK4 kinases causes PHAII in mutant KLHL3 knock-in mice.
Volume: 23
Issue: 19
Pages: 5052-60
Publication
First Author: Chi RA
Year: 2023
Journal: iScience
Title: WNK1 is required during male pachynema to sustain fertility.
Volume: 26
Issue: 9
Pages: 107616
Publication
First Author: Boyd-Shiwarski CR
Year: 2018
Journal: Mol Biol Cell
Title: Potassium-regulated distal tubule WNK bodies are kidney-specific WNK1 dependent.
Volume: 29
Issue: 4
Pages: 499-509
Publication
First Author: Köchl R
Year: 2016
Journal: Nat Immunol
Title: WNK1 kinase balances T cell adhesion versus migration in vivo.
Volume: 17
Issue: 9
Pages: 1075-83
Publication    
First Author: Köchl R
Year: 2020
Journal: Elife
Title: Critical role of WNK1 in MYC-dependent early mouse thymocyte development.
Volume: 9
Publication
First Author: Mayes-Hopfinger L
Year: 2021
Journal: Nat Commun
Title: Chloride sensing by WNK1 regulates NLRP3 inflammasome activation and pyroptosis.
Volume: 12
Issue: 1
Pages: 4546
Publication
First Author: Lee BH
Year: 2004
Journal: Mol Cell
Title: WNK1 phosphorylates synaptotagmin 2 and modulates its membrane binding.
Volume: 15
Issue: 5
Pages: 741-51
Publication
First Author: Roy A
Year: 2015
Journal: J Clin Invest
Title: Alternatively spliced proline-rich cassettes link WNK1 to aldosterone action.
Volume: 125
Issue: 9
Pages: 3433-48
Publication  
First Author: Chi RA
Year: 2020
Journal: JCI Insight
Title: WNK1 regulates uterine homeostasis and its ability to support pregnancy.
Volume: 5
Issue: 22
Publication
First Author: Xie J
Year: 2013
Journal: J Biol Chem
Title: WNK1 protein kinase regulates embryonic cardiovascular development through the OSR1 signaling cascade.
Volume: 288
Issue: 12
Pages: 8566-74
Publication
First Author: Rafael C
Year: 2018
Journal: Sci Rep
Title: Consequences of SPAK inactivation on Hyperkalemic Hypertension caused by WNK1 mutations: evidence for differential roles of WNK1 and WNK4.
Volume: 8
Issue: 1
Pages: 3249
Publication
First Author: Xie J
Year: 2009
Journal: Am J Pathol
Title: Endothelial-specific expression of WNK1 kinase is essential for angiogenesis and heart development in mice.
Volume: 175
Issue: 3
Pages: 1315-27
Publication  
First Author: Hayward DA
Year: 2023
Journal: J Exp Med
Title: B cell-intrinsic requirement for WNK1 kinase in antibody responses in mice.
Volume: 220
Issue: 3
Publication
First Author: Liu Z
Year: 2009
Journal: J Biol Chem
Title: Regulation of ROMK channel and K+ homeostasis by kidney-specific WNK1 kinase.
Volume: 284
Issue: 18
Pages: 12198-206
Publication
First Author: Bergaya S
Year: 2011
Journal: Hypertension
Title: WNK1 regulates vasoconstriction and blood pressure response to α 1-adrenergic stimulation in mice.
Volume: 58
Issue: 3
Pages: 439-45
Publication
First Author: Cheng CJ
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Kidney-specific WNK1 inhibits sodium reabsorption in the cortical thick ascending limb.
Volume: 303
Issue: 5
Pages: F667-73
Publication
First Author: Louis-Dit-Picard H
Year: 2020
Journal: J Clin Invest
Title: Mutation affecting the conserved acidic WNK1 motif causes inherited hyperkalemic hyperchloremic acidosis.
Volume: 130
Issue: 12
Pages: 6379-6394
Publication
First Author: Cheng CJ
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Kidney-specific WNK1 regulates sodium reabsorption and potassium secretion in mouse cortical collecting duct.
Volume: 304
Issue: 4
Pages: F397-402
Publication
First Author: Lee BH
Year: 2007
Journal: J Biol Chem
Title: Biological cross-talk between WNK1 and the transforming growth factor beta-Smad signaling pathway.
Volume: 282
Issue: 25
Pages: 17985-96
Publication
First Author: Mandai S
Year: 2018
Journal: Sci Rep
Title: WNK1 regulates skeletal muscle cell hypertrophy by modulating the nuclear localization and transcriptional activity of FOXO4.
Volume: 8
Issue: 1
Pages: 9101
Publication
First Author: Chung WY
Year: 2018
Journal: Mol Cell Biochem
Title: Overexpression of WNK1 in POMC-expressing neurons reduces weigh gain via WNK4-mediated degradation of Kir6.2.
Volume: 447
Issue: 1-2
Pages: 165-174
Publication
First Author: Chávez-Canales M
Year: 2014
Journal: Hypertension
Title: WNK-SPAK-NCC cascade revisited: WNK1 stimulates the activity of the Na-Cl cotransporter via SPAK, an effect antagonized by WNK4.
Volume: 64
Issue: 5
Pages: 1047-53
Publication
First Author: Susa K
Year: 2012
Journal: Clin Exp Nephrol
Title: Effect of heterozygous deletion of WNK1 on the WNK-OSR1/ SPAK-NCC/NKCC1/NKCC2 signal cascade in the kidney and blood vessels.
Volume: 16
Issue: 4
Pages: 530-8
Publication
First Author: Liu Z
Year: 2011
Journal: Hum Mol Genet
Title: Downregulation of NCC and NKCC2 cotransporters by kidney-specific WNK1 revealed by gene disruption and transgenic mouse models.
Volume: 20
Issue: 5
Pages: 855-66
Publication
First Author: Delaloy C
Year: 2006
Journal: Am J Pathol
Title: Cardiovascular expression of the mouse WNK1 gene during development and adulthood revealed by a BAC reporter assay.
Volume: 169
Issue: 1
Pages: 105-18
Publication
First Author: Shekarabi M
Year: 2013
Journal: PLoS One
Title: Comparative analysis of the expression profile of Wnk1 and Wnk1/Hsn2 splice variants in developing and adult mouse tissues.
Volume: 8
Issue: 2
Pages: e57807
Publication
First Author: Hadchouel J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Decreased ENaC expression compensates the increased NCC activity following inactivation of the kidney-specific isoform of WNK1 and prevents hypertension.
Volume: 107
Issue: 42
Pages: 18109-14
Publication
First Author: Dbouk HA
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Actions of the protein kinase WNK1 on endothelial cells are differentially mediated by its substrate kinases OSR1 and SPAK.
Volume: 111
Issue: 45
Pages: 15999-6004
Publication
First Author: Jiang ZY
Year: 2005
Journal: J Biol Chem
Title: Identification of WNK1 as a substrate of Akt/protein kinase B and a negative regulator of insulin-stimulated mitogenesis in 3T3-L1 cells.
Volume: 280
Issue: 22
Pages: 21622-8
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Wu P
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Role of WNK4 and kidney-specific WNK1 in mediating the effect of high dietary K+ intake on ROMK channel in the distal convoluted tubule.
Volume: 315
Issue: 2
Pages: F223-F230
Publication
First Author: O'Reilly M
Year: 2003
Journal: J Am Soc Nephrol
Title: WNK1, a gene within a novel blood pressure control pathway, tissue-specifically generates radically different isoforms with and without a kinase domain.
Volume: 14
Issue: 10
Pages: 2447-56
Publication
First Author: Wilson FH
Year: 2001
Journal: Science
Title: Human hypertension caused by mutations in WNK kinases.
Volume: 293
Issue: 5532
Pages: 1107-12
Publication
First Author: Yang CL
Year: 2003
Journal: J Clin Invest
Title: WNK kinases regulate thiazide-sensitive Na-Cl cotransport.
Volume: 111
Issue: 7
Pages: 1039-45
Publication
First Author: Yang D
Year: 2011
Journal: J Clin Invest
Title: IRBIT governs epithelial secretion in mice by antagonizing the WNK/SPAK kinase pathway.
Volume: 121
Issue: 3
Pages: 956-65
Publication
First Author: Vidal-Petiot E
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: WNK1-related Familial Hyperkalemic Hypertension results from an increased expression of L-WNK1 specifically in the distal nephron.
Volume: 110
Issue: 35
Pages: 14366-71
Publication
First Author: Choate KA
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: WNK1, a kinase mutated in inherited hypertension with hyperkalemia, localizes to diverse Cl- -transporting epithelia.
Volume: 100
Issue: 2
Pages: 663-8
Publication
First Author: Kahle KT
Year: 2016
Journal: Sci Signal
Title: Inhibition of the kinase WNK1/HSN2 ameliorates neuropathic pain by restoring GABA inhibition.
Volume: 9
Issue: 421
Pages: ra32
Publication
First Author: Sato A
Year: 2013
Journal: PLoS One
Title: WNK signaling is involved in neural development via Lhx8/Awh expression.
Volume: 8
Issue: 1
Pages: e55301
Publication
First Author: Friedel P
Year: 2015
Journal: Sci Signal
Title: WNK1-regulated inhibitory phosphorylation of the KCC2 cotransporter maintains the depolarizing action of GABA in immature neurons.
Volume: 8
Issue: 383
Pages: ra65
Publication
First Author: Izadifar A
Year: 2021
Journal: Neuron
Title: Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.
Volume: 109
Issue: 18
Pages: 2864-2883.e8
Publication
First Author: Shibata S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Kelch-like 3 and Cullin 3 regulate electrolyte homeostasis via ubiquitination and degradation of WNK4.
Volume: 110
Issue: 19
Pages: 7838-43
Publication
First Author: Ostrosky-Frid M
Year: 2021
Journal: Am J Physiol Renal Physiol
Title: Role of KLHL3 and dietary K+ in regulating KS-WNK1 expression.
Volume: 320
Issue: 5
Pages: F734-F747
Publication
First Author: Rinehart J
Year: 2011
Journal: J Biol Chem
Title: WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters.
Volume: 286
Issue: 34
Pages: 30171-80
Publication  
First Author: Watanabe M
Year: 2019
Journal: Sci Signal
Title: Developmentally regulated KCC2 phosphorylation is essential for dynamic GABA-mediated inhibition and survival.
Volume: 12
Issue: 603
Publication  
First Author: Zhang J
Year: 2016
Journal: Sci Rep
Title: Functional kinomics establishes a critical node of volume-sensitive cation-Cl- cotransporter regulation in the mammalian brain.
Volume: 6
Pages: 35986
Publication
First Author: Jensen P
Year: 2004
Journal: Brain Res Mol Brain Res
Title: A neurogenomics approach to gene expression analysis in the developing brain.
Volume: 132
Issue: 2
Pages: 116-27
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication      
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Subramanya AR
Year: 2006
Journal: Am J Physiol Renal Physiol
Title: Dominant-negative regulation of WNK1 by its kidney-specific kinase-defective isoform.
Volume: 290
Issue: 3
Pages: F619-24
Publication
First Author: Delaloy C
Year: 2008
Journal: Hypertension
Title: Deletion of WNK1 first intron results in misregulation of both isoforms in renal and extrarenal tissues.
Volume: 52
Issue: 6
Pages: 1149-54
Publication  
First Author: Zeng G
Year: 2005
Journal: Gene
Title: Expression of the mouse WNK1 gene in correlation with ganglioside GD3 and functional analysis of the mouse WNK1 promoter.
Volume: 344
Pages: 233-9
Publication
First Author: Lafreniere RG
Year: 2004
Journal: Am J Hum Genet
Title: Identification of a novel gene (HSN2) causing hereditary sensory and autonomic neuropathy type II through the Study of Canadian Genetic Isolates.
Volume: 74
Issue: 5
Pages: 1064-73
Publication
First Author: Susa K
Year: 2017
Journal: Biochem Biophys Res Commun
Title: WNK4 is indispensable for the pathogenesis of pseudohypoaldosteronism type II caused by mutant KLHL3.
Volume: 491
Issue: 3
Pages: 727-732
Publication  
First Author: Sasaki E
Year: 2017
Journal: Mol Cell Biol
Title: KLHL3 Knockout Mice Reveal the Physiological Role of KLHL3 and the Pathophysiology of Pseudohypoaldosteronism Type II Caused by Mutant KLHL3.
Volume: 37
Issue: 7
Publication
First Author: Park S
Year: 2013
Journal: Gastroenterology
Title: Irbit mediates synergy between ca(2+) and cAMP signaling pathways during epithelial transport in mice.
Volume: 145
Issue: 1
Pages: 232-41
Publication
First Author: Boyd-Shiwarski CR
Year: 2022
Journal: Cell
Title: WNK kinases sense molecular crowding and rescue cell volume via phase separation.
Volume: 185
Issue: 24
Pages: 4488-4506.e20
Publication
First Author: Yang SS
Year: 2007
Journal: Cell Metab
Title: Molecular pathogenesis of pseudohypoaldosteronism type II: generation and analysis of a Wnk4(D561A/+) knockin mouse model.
Volume: 5
Issue: 5
Pages: 331-44
Publication
First Author: Chiga M
Year: 2008
Journal: Kidney Int
Title: Dietary salt regulates the phosphorylation of OSR1/SPAK kinases and the sodium chloride cotransporter through aldosterone.
Volume: 74
Issue: 11
Pages: 1403-9
Publication
First Author: Richards J
Year: 2014
Journal: J Biol Chem
Title: A role for the circadian clock protein Per1 in the regulation of the NaCl co-transporter (NCC) and the with-no-lysine kinase (WNK) cascade in mouse distal convoluted tubule cells.
Volume: 289
Issue: 17
Pages: 11791-806
Publication
First Author: Wilson FH
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Molecular pathogenesis of inherited hypertension with hyperkalemia: the Na-Cl cotransporter is inhibited by wild-type but not mutant WNK4.
Volume: 100
Issue: 2
Pages: 680-4
Publication
First Author: Yang CL
Year: 2007
Journal: J Clin Invest
Title: The thiazide-sensitive Na-Cl cotransporter is regulated by a WNK kinase signaling complex.
Volume: 117
Issue: 11
Pages: 3403-11
Publication
First Author: Al-Qusairi L
Year: 2017
Journal: J Am Soc Nephrol
Title: Renal Tubular Ubiquitin-Protein Ligase NEDD4-2 Is Required for Renal Adaptation during Long-Term Potassium Depletion.
Volume: 28
Issue: 8
Pages: 2431-2442
Publication
First Author: Al-Qusairi L
Year: 2016
Journal: Am J Physiol Renal Physiol
Title: Renal tubular SGK1 deficiency causes impaired K+ excretion via loss of regulation of NEDD4-2/WNK1 and ENaC.
Volume: 311
Issue: 2
Pages: F330-42
Publication
First Author: Oi K
Year: 2012
Journal: Biol Open
Title: A minor role of WNK3 in regulating phosphorylation of renal NKCC2 and NCC co-transporters in vivo.
Volume: 1
Issue: 2
Pages: 120-7
Publication  
First Author: Takahashi D
Year: 2014
Journal: Biosci Rep
Title: WNK4 is the major WNK positively regulating NCC in the mouse kidney.
Volume: 34
Issue: 3