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Search results 1001 to 1100 out of 1129 for Cftr

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Type Details Score
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Donowitz M
Year: 2011
Journal: Physiol Genomics
Title: Alterations in the proteome of the NHERF2 knockout mouse jejunal brush border membrane vesicles.
Volume: 43
Issue: 11
Pages: 674-84
GXD Expression
Probe: MGI:1049495
Assay Type: RNA in situ
Annotation Date: 2023-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3576022
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7444205
Age: embryonic day 14.5
Image: S1B
Note: Expression was detected primarily in the valve endothelium.
Specimen Label: S1B
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5588826
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:5602959
Age: embryonic day 15.5
Image: S9A E15.5
Note: Expression is present in the stereocilia on both inner hair cells (IHC) and outer hair cells (OHC).
Specimen Label: S9A E15.5
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:1049495
Assay Type: RNA in situ
Annotation Date: 2023-03-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3515422
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:7444205
Age: embryonic day 14.5
Image: S1B
Note: Expression was detected primarily in the valve endothelium.
Specimen Label: S1B
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:5588826
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906127
Pattern: Regionally restricted
Stage: TS27
Assay Id: MGI:5602959
Age: postnatal day 0
Image: S9A P0
Note: Expression is present in the stereocilia on both inner hair cells (IHC) and outer hair cells (OHC). This staining is more intense postnatally (versus embryonic staining).
Specimen Label: S9A P0
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5588826
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5602959
Age: postnatal day 5
Image: S9A P5
Note: Expression is present in the stereocilia on both inner hair cells (IHC) and outer hair cells (OHC).
Specimen Label: S9A P5
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5588826
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5602959
Age: postnatal day 15
Image: S9A P15
Note: Expression is present in the stereocilia on both inner hair cells (IHC) and outer hair cells (OHC).
Specimen Label: S9A P15
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:5588826
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5602959
Age: postnatal
Image: S9B wt
Note: Expression is present in hair bundles.
Specimen Label: S9B wt
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:5588826
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-27
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1906128
Stage: TS28
Assay Id: MGI:5602959
Age: postnatal
Image: S9B -/-
Specimen Label: S9B -/-
Detected: false
Specimen Num: 7
GXD Expression
Probe: MGI:5588826
Assay Type: Immunohistochemistry
Annotation Date: 2014-10-27
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1906128
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:5602959
Age: postnatal day 90
Image: S9A P90
Note: Expression is present in the stereocilia on both inner hair cells (IHC) and outer hair cells (OHC). Most of the staining is located in the stereocilia basal region.
Specimen Label: S9A P90
Detected: true
Specimen Num: 5
Publication    
First Author: Sarker AH
Year: 2000
Journal: GenBank Submission
Title: Mus musculus mRNA for mSlc9a3r2/E3karp/Sip-1/Tka-1/Octs2, complete cds
Pages: AB026489
Publication
First Author: Wang S
Year: 2000
Journal: Cell
Title: Accessory protein facilitated CFTR-CFTR interaction, a molecular mechanism to potentiate the chloride channel activity.
Volume: 103
Issue: 1
Pages: 169-79
Publication  
First Author: Zhou Z
Year: 2011
Journal: J Cyst Fibros
Title: The ENaC-overexpressing mouse as a model of cystic fibrosis lung disease.
Volume: 10 Suppl 2
Pages: S172-82
Publication
First Author: Cabrita I
Year: 2020
Journal: Nat Commun
Title: Cyst growth in ADPKD is prevented by pharmacological and genetic inhibition of TMEM16A in vivo.
Volume: 11
Issue: 1
Pages: 4320
Publication
First Author: Takiar V
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Activating AMP-activated protein kinase (AMPK) slows renal cystogenesis.
Volume: 108
Issue: 6
Pages: 2462-7
Publication
First Author: Perraud F
Year: 1992
Journal: Oncogene
Title: The promoter of the human cystic fibrosis transmembrane conductance regulator gene directing SV40 T antigen expression induces malignant proliferation of ependymal cells in transgenic mice.
Volume: 7
Issue: 5
Pages: 993-7
Protein
Organism: Mus musculus/domesticus
Length: 31  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 252  
Fragment?: true
Publication
First Author: van der Velden LM
Year: 2010
Journal: J Biol Chem
Title: Heteromeric interactions required for abundance and subcellular localization of human CDC50 proteins and class 1 P4-ATPases.
Volume: 285
Issue: 51
Pages: 40088-96
Publication
First Author: Bachmann O
Year: 2003
Journal: Am J Physiol Gastrointest Liver Physiol
Title: cAMP-mediated regulation of murine intestinal/pancreatic Na+/HCO3- cotransporter subtype pNBC1.
Volume: 284
Issue: 1
Pages: G37-45
Publication
First Author: Singh AK
Year: 2013
Journal: J Physiol
Title: Molecular transport machinery involved in orchestrating luminal acid-induced duodenal bicarbonate secretion in vivo.
Volume: 591
Issue: 21
Pages: 5377-91
Publication
First Author: Flagella M
Year: 1999
Journal: J Biol Chem
Title: Mice lacking the basolateral Na-K-2Cl cotransporter have impaired epithelial chloride secretion and are profoundly deaf.
Volume: 274
Issue: 38
Pages: 26946-55
Publication
First Author: Chow YH
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Development of an epithelium-specific expression cassette with human DNA regulatory elements for transgene expression in lung airways.
Volume: 94
Issue: 26
Pages: 14695-700
Publication
First Author: Maouche K
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Contribution of α7 nicotinic receptor to airway epithelium dysfunction under nicotine exposure.
Volume: 110
Issue: 10
Pages: 4099-104
Publication
First Author: Thomas A
Year: 2018
Journal: J Biol Chem
Title: AC6 is the major adenylate cyclase forming a diarrheagenic protein complex with cystic fibrosis transmembrane conductance regulator in cholera.
Volume: 293
Issue: 33
Pages: 12949-12959
Publication
First Author: Fenton RA
Year: 2019
Journal: J Infect Dis
Title: Adenylyl Cyclase 6 Expression Is Essential for Cholera Toxin-Induced Diarrhea.
Volume: 220
Issue: 11
Pages: 1719-1728
Publication
First Author: Yanda MK
Year: 2019
Journal: J Biol Chem
Title: Pharmacological reversal of renal cysts from secretion to absorption suggests a potential therapeutic strategy for managing autosomal dominant polycystic kidney disease.
Volume: 294
Issue: 45
Pages: 17090-17104
Publication
First Author: Burnight ER
Year: 2012
Journal: Am J Respir Cell Mol Biol
Title: Transcriptional targeting in the airway using novel gene regulatory elements.
Volume: 47
Issue: 2
Pages: 227-33
Publication
First Author: Yu K
Year: 2010
Journal: J Clin Invest
Title: Bestrophin-2 mediates bicarbonate transport by goblet cells in mouse colon.
Volume: 120
Issue: 5
Pages: 1722-35
Publication
First Author: Escoffier J
Year: 2012
Journal: J Cell Sci
Title: Flow cytometry analysis reveals a decrease in intracellular sodium during sperm capacitation.
Volume: 125
Issue: Pt 2
Pages: 473-85
Publication
First Author: Zhou H
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Ginkgolide B inhibits renal cyst development in in vitro and in vivo cyst models.
Volume: 302
Issue: 10
Pages: F1234-42
Publication    
First Author: Saint-Criq V
Year: 2022
Journal: Elife
Title: Inhibition of the sodium-dependent HCO(3)(-) transporter SLC4A4, produces a cystic fibrosis-like airway disease phenotype.
Volume: 11
Publication
First Author: Forteza R
Year: 2019
Journal: Mol Biol Cell
Title: Glucocorticoids and myosin5b loss of function induce heightened PKA signaling in addition to membrane traffic defects.
Volume: 30
Issue: 26
Pages: 3076-3089
Publication
First Author: Pattison AM
Year: 2016
Journal: Infect Immun
Title: Intestinal Enteroids Model Guanylate Cyclase C-Dependent Secretion Induced by Heat-Stable Enterotoxins.
Volume: 84
Issue: 10
Pages: 3083-91
Publication
First Author: Jung ES
Year: 2014
Journal: J Physiol
Title: Shank2 mutant mice display a hypersecretory response to cholera toxin.
Volume: 592
Issue: 8
Pages: 1809-21
Publication
First Author: El Khouri E
Year: 2018
Journal: Mol Reprod Dev
Title: Slc26a3 deficiency is associated with epididymis dysplasia and impaired sperm fertilization potential in the mouse.
Volume: 85
Issue: 8-9
Pages: 682-695
Publication
First Author: Gentzsch M
Year: 2001
Journal: J Biol Chem
Title: Localization of sequences within the C-terminal domain of the cystic fibrosis transmembrane conductance regulator which impact maturation and stability.
Volume: 276
Issue: 2
Pages: 1291-8
Publication
First Author: Brady KG
Year: 2001
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Examining basal chloride transport using the nasal potential difference response in a murine model.
Volume: 281
Issue: 5
Pages: L1173-9
Publication
First Author: Cheng J
Year: 2002
Journal: J Biol Chem
Title: A Golgi-associated PDZ domain protein modulates cystic fibrosis transmembrane regulator plasma membrane expression.
Volume: 277
Issue: 5
Pages: 3520-9
Publication
First Author: Ehrlich G
Year: 1992
Journal: Genomics
Title: Mapping the human acetylcholinesterase gene to chromosome 7q22 by fluorescent in situ hybridization coupled with selective PCR amplification from a somatic hybrid cell panel and chromosome-sorted DNA libraries.
Volume: 13
Issue: 4
Pages: 1192-7
Publication
First Author: Yan W
Year: 2004
Journal: J Biol Chem
Title: Cystic fibrosis transmembrane conductance regulator differentially regulates human and mouse epithelial sodium channels in Xenopus oocytes.
Volume: 279
Issue: 22
Pages: 23183-92
Publication
First Author: Gnann A
Year: 2004
Journal: Mol Biol Cell
Title: Cystic fibrosis transmembrane conductance regulator degradation depends on the lectins Htm1p/EDEM and the Cdc48 protein complex in yeast.
Volume: 15
Issue: 9
Pages: 4125-35
Publication
First Author: Peña-Münzenmayer G
Year: 2005
Journal: J Cell Sci
Title: Basolateral localization of native ClC-2 chloride channels in absorptive intestinal epithelial cells and basolateral sorting encoded by a CBS-2 domain di-leucine motif.
Volume: 118
Issue: Pt 18
Pages: 4243-52
Publication
First Author: Factor P
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Adenosine regulation of alveolar fluid clearance.
Volume: 104
Issue: 10
Pages: 4083-8
Publication
First Author: Swiatecka-Urban A
Year: 2007
Journal: J Biol Chem
Title: Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells.
Volume: 282
Issue: 32
Pages: 23725-36
Publication
First Author: Raksaseri P
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Activation of liver X receptors reduces CFTR-mediated Cl(-) transport in kidney collecting duct cells.
Volume: 305
Issue: 4
Pages: F583-91
Publication
First Author: Stark JM
Year: 2010
Journal: J Virol
Title: Genomewide association analysis of respiratory syncytial virus infection in mice.
Volume: 84
Issue: 5
Pages: 2257-69
Protein
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 529  
Fragment?: false
Publication
First Author: Engevik AC
Year: 2018
Journal: Gastroenterology
Title: Loss of MYO5B Leads to Reductions in Na(+) Absorption With Maintenance of CFTR-Dependent Cl(-) Secretion in Enterocytes.
Volume: 155
Issue: 6
Pages: 1883-1897.e10
Publication
First Author: Kirkland JG
Year: 2007
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Agonists of protease-activated receptors 1 and 2 stimulate electrolyte secretion from mouse gallbladder.
Volume: 293
Issue: 1
Pages: G335-46
Publication
First Author: Ruan YC
Year: 2012
Journal: J Physiol
Title: ATP secretion in the male reproductive tract: essential role of CFTR.
Volume: 590
Issue: 17
Pages: 4209-22
Publication
First Author: Lidington D
Year: 2022
Journal: Stroke
Title: Circadian Rhythmicity in Cerebral Microvascular Tone Influences Subarachnoid Hemorrhage-Induced Injury.
Volume: 53
Issue: 1
Pages: 249-259
Publication
First Author: Mukaibo T
Year: 2018
Journal: J Dent Res
Title: Defective NaCl Reabsorption in Salivary Glands of Eda-Null X-LHED Mice.
Volume: 97
Issue: 11
Pages: 1244-1251
Publication
First Author: Lee ER
Year: 1996
Journal: Hum Gene Ther
Title: Detailed analysis of structures and formulations of cationic lipids for efficient gene transfer to the lung.
Volume: 7
Issue: 14
Pages: 1701-17
Publication
First Author: Vuillaumier S
Year: 1997
Journal: Mol Biol Evol
Title: Phylogenetic analysis of cystic fibrosis transmembrane conductance regulator gene in mammalian species argues for the development of a rabbit model for cystic fibrosis.
Volume: 14
Issue: 4
Pages: 372-80
Publication
First Author: Hill WG
Year: 1997
Journal: Biochem Mol Med
Title: Organ-specific over-sulfation of glycosaminoglycans and altered extracellular matrix in a mouse model of cystic fibrosis.
Volume: 62
Issue: 1
Pages: 113-22
Publication
First Author: Falany CN
Year: 2009
Journal: J Steroid Biochem Mol Biol
Title: Regulation of hepatic sulfotransferase (SULT) 1E1 expression and effects on estrogenic activity in cystic fibrosis (CF).
Volume: 114
Issue: 1-2
Pages: 113-9
Publication
First Author: Speak AO
Year: 2017
Journal: Nat Protoc
Title: A high-throughput in vivo screening method in the mouse for identifying regulators of metastatic colonization.
Volume: 12
Issue: 12
Pages: 2465-2477
Publication
First Author: Chen M
Year: 2010
Journal: J Physiol
Title: Loss of PDZ-adaptor protein NHERF2 affects membrane localization and cGMP- and [Ca2+]- but not cAMP-dependent regulation of Na+/H+ exchanger 3 in murine intestine.
Volume: 588
Issue: Pt 24
Pages: 5049-63
Publication
First Author: Murtazina R
Year: 2011
Journal: Am J Physiol Cell Physiol
Title: NHERF2 is necessary for basal activity, second messenger inhibition, and LPA stimulation of NHE3 in mouse distal ileum.
Volume: 301
Issue: 1
Pages: C126-36
Publication
First Author: Zhang J
Year: 1999
Journal: Int J Dev Biol
Title: In vitro binding and expression studies demonstrate a role for the mouse Sry Q-rich domain in sex determination.
Volume: 43
Issue: 3
Pages: 219-27
Publication    
First Author: Sarker AH
Year: 2000
Journal: GenBank Submission
Title: Mus musculus gene for mSlc9a3r2/E3karp/Sip-1/Tka-1/Octs2 and mNthl1, complete cds and partial sequence
Pages: AB026490
Protein
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 403  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 463  
Fragment?: false
Publication
First Author: Cunningham R
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Urine electrolyte, mineral, and protein excretion in NHERF-2 and NHERF-1 null mice.
Volume: 294
Issue: 4
Pages: F1001-7
Publication  
First Author: Ritter-Makinson SL
Year: 2017
Journal: Neuroscience
Title: Group II metabotropic glutamate receptor interactions with NHERF scaffold proteins: Implications for receptor localization in brain.
Volume: 353
Pages: 58-75
Publication
First Author: Yoshida M
Year: 2016
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Deletion of Na+/H+ exchanger regulatory factor 2 represses colon cancer progress by suppression of Stat3 and CD24.
Volume: 310
Issue: 8
Pages: G586-98
Publication
First Author: Avula LR
Year: 2018
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Both NHERF3 and NHERF2 are necessary for multiple aspects of acute regulation of NHE3 by elevated Ca2+, cGMP, and lysophosphatidic acid.
Volume: 314
Issue: 1
Pages: G81-G90
Publication
First Author: Palmada M
Year: 2005
Journal: Cell Physiol Biochem
Title: Requirement of PDZ domains for the stimulation of the epithelial Ca2+ channel TRPV5 by the NHE regulating factor NHERF2 and the serum and glucocorticoid inducible kinase SGK1.
Volume: 15
Issue: 1-4
Pages: 175-82
Publication
First Author: Andersson ER
Year: 2018
Journal: Gastroenterology
Title: Mouse Model of Alagille Syndrome and Mechanisms of Jagged1 Missense Mutations.
Volume: 154
Issue: 4
Pages: 1080-1095
Publication
First Author: Innes BA
Year: 2001
Journal: Mamm Genome
Title: Submucosal gland distribution in the mouse has a genetic determination localized on chromosome 9.
Volume: 12
Issue: 2
Pages: 124-8
Publication  
First Author: Di Paola M
Year: 2017
Journal: MBio
Title: SLC6A14 Is a Genetic Modifier of Cystic Fibrosis That Regulates Pseudomonas aeruginosa Attachment to Human Bronchial Epithelial Cells.
Volume: 8
Issue: 6
Publication  
First Author: Vuillaumier S
Year: 1997
Journal: Biochem J
Title: Cross-species characterization of the promoter region of the cystic fibrosis transmembrane conductance regulator gene reveals multiple levels of regulation.
Volume: 327 ( Pt 3)
Pages: 651-62
Protein
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: true
Publication
First Author: He P
Year: 2011
Journal: Mol Biol Cell
Title: Serum- and glucocorticoid-induced kinase 3 in recycling endosomes mediates acute activation of Na+/H+ exchanger NHE3 by glucocorticoids.
Volume: 22
Issue: 20
Pages: 3812-25
Publication
First Author: Vogl C
Year: 2017
Journal: EMBO Rep
Title: The BEACH protein LRBA is required for hair bundle maintenance in cochlear hair cells and for hearing.
Volume: 18
Issue: 11
Pages: 2015-2029
Publication
First Author: Shenolikar S
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Targeted disruption of the mouse NHERF-1 gene promotes internalization of proximal tubule sodium-phosphate cotransporter type IIa and renal phosphate wasting.
Volume: 99
Issue: 17
Pages: 11470-5
Publication
First Author: He P
Year: 2015
Journal: J Clin Invest
Title: Restoration of Na+/H+ exchanger NHE3-containing macrocomplexes ameliorates diabetes-associated fluid loss.
Volume: 125
Issue: 9
Pages: 3519-31
Publication
First Author: Malmberg EK
Year: 2008
Journal: Biochem J
Title: The C-terminus of the transmembrane mucin MUC17 binds to the scaffold protein PDZK1 that stably localizes it to the enterocyte apical membrane in the small intestine.
Volume: 410
Issue: 2
Pages: 283-9
Publication
First Author: Lin S
Year: 2010
Journal: Gastroenterology
Title: Lysophosphatidic acid stimulates the intestinal brush border Na(+)/H(+) exchanger 3 and fluid absorption via LPA(5) and NHERF2.
Volume: 138
Issue: 2
Pages: 649-58
Protein
Organism: Mus musculus/domesticus
Length: 999  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 894  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 239  
Fragment?: false
Publication
First Author: Dean M
Year: 2001
Journal: J Lipid Res
Title: The human ATP-binding cassette (ABC) transporter superfamily.
Volume: 42
Issue: 7
Pages: 1007-17
Publication
First Author: Terawaki S
Year: 2006
Journal: Structure
Title: Structural basis for NHERF recognition by ERM proteins.
Volume: 14
Issue: 4
Pages: 777-89
Publication
First Author: Gisler SM
Year: 2003
Journal: Kidney Int
Title: PDZK1: I. a major scaffolder in brush borders of proximal tubular cells.
Volume: 64
Issue: 5
Pages: 1733-45
Publication
First Author: Thevenet L
Year: 2005
Journal: J Biol Chem
Title: NHERF2/SIP-1 interacts with mouse SRY via a different mechanism than human SRY.
Volume: 280
Issue: 46
Pages: 38625-30