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Search results 1 to 100 out of 113 for Gclc

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Type Details Score
Publication
28158580 | J:241658
First Author: Feng W
Year: 2017
Journal: Hum Mol Genet
Title: Gclc deficiency in mouse CNS causes mitochondrial damage and neurodegeneration.
Volume: 26
Issue: 7
Pages: 1376-1390
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Publication
17464988 | J:202376
First Author: Chen Y
Year: 2007
Journal: Hepatology
Title: Hepatocyte-specific Gclc deletion leads to rapid onset of steatosis with mitochondrial injury and liver failure.
Volume: 45
Issue: 5
Pages: 1118-28
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Publication
28423341 | J:259281
First Author: Mak TW
Year: 2017
Journal: Immunity
Title: Glutathione Primes T Cell Metabolism for Inflammation.
Volume: 46
Issue: 4
Pages: 675-689
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Publication
23226398 | J:194778
First Author: Fan X
Year: 2012
Journal: PLoS One
Title: The LEGSKO mouse: a mouse model of age-related nuclear cataract based on genetic suppression of lens glutathione synthesis.
Volume: 7
Issue: 11
Pages: e50832
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Publication
11118286 | J:66499
First Author: Dalton TP
Year: 2000
Journal: Biochem Biophys Res Commun
Title: Knockout of the mouse glutamate cysteine ligase catalytic subunit (Gclc) gene: embryonic lethal when homozygous, and proposed model for moderate glutathione deficiency when heterozygous.
Volume: 279
Issue: 2
Pages: 324-9
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Publication
20332089 | J:163893
First Author: Krejsa CM
Year: 2010
Journal: J Biol Chem
Title: Rapid activation of glutamate cysteine ligase following oxidative stress.
Volume: 285
Issue: 21
Pages: 16116-24
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Publication
32213345 | J:297232
First Author: Kurniawan H
Year: 2020
Journal: Cell Metab
Title: Glutathione Restricts Serine Metabolism to Preserve Regulatory T Cell Function.
Volume: 31
Issue: 5
Pages: 920-936.e7
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Publication
35379825 | J:330346
First Author: Franchina DG
Year: 2022
Journal: Nat Commun
Title: Glutathione-dependent redox balance characterizes the distinct metabolic properties of follicular and marginal zone B cells.
Volume: 13
Issue: 1
Pages: 1789
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Publication
15288121 | J:91536
First Author: Botta D
Year: 2004
Journal: Free Radic Biol Med
Title: Glutamate-cysteine ligase attenuates TNF-induced mitochondrial injury and apoptosis.
Volume: 37
Issue: 5
Pages: 632-42
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Publication
12384496 | J:80927
First Author: Yang Y
Year: 2002
Journal: J Biol Chem
Title: Initial characterization of the glutamate-cysteine ligase modifier subunit Gclm(-/-) knockout mouse. Novel model system for a severely compromised oxidative stress response.
Volume: 277
Issue: 51
Pages: 49446-52
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Publication
16081425 | J:102460
First Author: Chen Y
Year: 2005
Journal: J Biol Chem
Title: Glutamate cysteine ligase catalysis: dependence on ATP and modifier subunit for regulation of tissue glutathione levels.
Volume: 280
Issue: 40
Pages: 33766-74
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Publication
11933164 | J:75783
First Author: Díaz D
Year: 2002
Journal: Mol Reprod Dev
Title: Expression of glutamate-cysteine ligase during mouse development.
Volume: 62
Issue: 1
Pages: 83-91
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Publication
15336720 | J:93103
First Author: Díaz D
Year: 2004
Journal: Reprod Toxicol
Title: Effect of methylmercury on glutamate-cysteine ligase expression in the placenta and yolk sac during mouse development.
Volume: 19
Issue: 1
Pages: 117-29
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Publication
27140233 | J:330998
 
First Author: Sánchez-Vallejo V
Year: 2016
Journal: Free Radic Biol Med
Title: Alterations in glutamate cysteine ligase content in the retina of two retinitis pigmentosa animal models.
Volume: 96
Pages: 245-54
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Publication
36670138 | J:333385
First Author: Hashimoto S
Year: 2023
Journal: Sci Rep
Title: Neuronal glutathione loss leads to neurodegeneration involving gasdermin activation.
Volume: 13
Issue: 1
Pages: 1109
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Publication
9223101 | J:41600
First Author: Kang Y
Year: 1997
Journal: Neuroreport
Title: Cloning/brain localization of mouse glutamylcysteine synthetase heavy chain mRNA.
Volume: 8
Issue: 8
Pages: 2053-60
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9224945 | J:41485
First Author: Reid LL
Year: 1997
Journal: Biochim Biophys Acta
Title: Molecular cloning and sequencing of the cDNA encoding the catalytic subunit of mouse glutamate-cysteine ligase.
Volume: 1352
Issue: 3
Pages: 233-7
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Publication
28525556 | J:242122
First Author: Whitson JA
Year: 2017
Journal: Invest Ophthalmol Vis Sci
Title: Transcriptome of the GSH-Depleted Lens Reveals Changes in Detoxification and EMT Signaling Genes, Transport Systems, and Lipid Homeostasis.
Volume: 58
Issue: 5
Pages: 2666-2684
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Publication
28827139 | J:250101
First Author: Wei Z
Year: 2017
Journal: Am J Pathol
Title: Reduced Glutathione Level Promotes Epithelial-Mesenchymal Transition in Lens Epithelial Cells via a Wnt/β-Catenin-Mediated Pathway: Relevance for Cataract Therapy.
Volume: 187
Issue: 11
Pages: 2399-2412
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28951044 | J:287904
 
First Author: Whitson JA
Year: 2017
Journal: Free Radic Biol Med
Title: Proteomic analysis of the glutathione-deficient LEGSKO mouse lens reveals activation of EMT signaling, loss of lens specific markers, and changes in stress response proteins.
Volume: 113
Pages: 84-96
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Publication
27472077 | J:286662
First Author: Whitson JA
Year: 2016
Journal: Invest Ophthalmol Vis Sci
Title: Evidence of Dual Mechanisms of Glutathione Uptake in the Rodent Lens: A Novel Role for Vitreous Humor in Lens Glutathione Homeostasis.
Volume: 57
Issue: 8
Pages: 3914-25
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Publication
28177569 | J:241227
First Author: Wang B
Year: 2017
Journal: Aging Cell
Title: The oxidized thiol proteome in aging and cataractous mouse and human lens revealed by ICAT labeling.
Volume: 16
Issue: 2
Pages: 244-261
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Publication
16840778 | J:117297
First Author: Botta D
Year: 2006
Journal: J Biol Chem
Title: Acetaminophen-induced liver injury is attenuated in male glutamate-cysteine ligase transgenic mice.
Volume: 281
Issue: 39
Pages: 28865-75
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Publication
11032771 | J:74043
First Author: Stover SK
Year: 2000
Journal: Toxicol Appl Pharmacol
Title: Regulation of gamma-glutamate-cysteine ligase expression by oxidative stress in the mouse preimplantation embryo.
Volume: 168
Issue: 2
Pages: 153-9
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Publication
18094238 | J:129268
First Author: Chinta SJ
Year: 2007
Journal: J Neurosci
Title: Inducible alterations of glutathione levels in adult dopaminergic midbrain neurons result in nigrostriatal degeneration.
Volume: 27
Issue: 51
Pages: 13997-4006
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Publication
12063408 | J:78157
First Author: Wydner KS
Year: 2001
Journal: Cytogenet Cell Genet
Title: The mouse orthologue of the human ionotropic glutamate receptor-like gene (GRINL1A) maps(1) to mouse chromosome 9.
Volume: 95
Issue: 3-4
Pages: 240-1
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Publication
17000861 | J:129361
First Author: Giordano G
Year: 2006
Journal: Mol Pharmacol
Title: Neurotoxicity of domoic Acid in cerebellar granule neurons in a genetic model of glutathione deficiency.
Volume: 70
Issue: 6
Pages: 2116-26
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Publication
20696779 | J:163690
First Author: Khouzami L
Year: 2010
Journal: Am J Pathol
Title: Delayed cardiomyopathy in dystrophin deficient mdx mice relies on intrinsic glutathione resource.
Volume: 177
Issue: 3
Pages: 1356-64
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Publication
10805773 | J:62177
First Author: Shi ZZ
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Glutathione synthesis is essential for mouse development but not for cell growth in culture.
Volume: 97
Issue: 10
Pages: 5101-6
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Publication
26808544 | J:232344
First Author: Telorack M
Year: 2016
Journal: PLoS Genet
Title: A Glutathione-Nrf2-Thioredoxin Cross-Talk Ensures Keratinocyte Survival and Efficient Wound Repair.
Volume: 12
Issue: 1
Pages: e1005800
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Publication
10966520 | J:74071
First Author: Thompson SA
Year: 2000
Journal: Toxicol Sci
Title: Modulation of glutathione and glutamate-L-cysteine ligase by methylmercury during mouse development.
Volume: 57
Issue: 1
Pages: 141-6
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Publication
8825659 | J:30588
First Author: Tsuchiya K
Year: 1995
Journal: Genomics
Title: Mapping of the glutamate-cysteine ligase catalytic subunit gene (GLCLC) to human chromosome 6p12 and mouse chromosome 9D-E and of the regulatory subunit gene (GLCLR) to human chromosome 1p21-p22 and mouse chromosome 3H1-3.
Volume: 30
Issue: 3
Pages: 630-2
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Publication
37432749 | J:339074
 
First Author: Hu G
Year: 2023
Journal: JCI Insight
Title: Glutathione limits RUNX2 oxidation and degradation to regulate bone formation.
Volume: 8
Issue: 16
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Publication
23671099 | J:197430
First Author: Cabungcal JH
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Perineuronal nets protect fast-spiking interneurons against oxidative stress.
Volume: 110
Issue: 22
Pages: 9130-5
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30198844 | J:269762
   
First Author: Lian G
Year: 2018
Journal: Elife
Title: Glutathione de novo synthesis but not recycling process coordinates with glutamine catabolism to control redox homeostasis and directs murine T cell differentiation.
Volume: 7
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Publication
17189825 | J:117265
First Author: Habib GM
Year: 2007
Journal: Free Radic Biol Med
Title: Glutathione protects cells against arsenite-induced toxicity.
Volume: 42
Issue: 2
Pages: 191-201
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Publication
35655024 | J:334086
First Author: He W
Year: 2022
Journal: Nat Metab
Title: Mesaconate is synthesized from itaconate and exerts immunomodulatory effects in macrophages.
Volume: 4
Issue: 5
Pages: 524-533
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Publication
20463017 | J:288986
First Author: Mandal PK
Year: 2010
Journal: J Biol Chem
Title: System x(c)- and thioredoxin reductase 1 cooperatively rescue glutathione deficiency.
Volume: 285
Issue: 29
Pages: 22244-53
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Publication
29618580 | J:262214
First Author: Okuno Y
Year: 2018
Journal: Diabetes
Title: Oxidative Stress Inhibits Healthy Adipose Expansion Through Suppression of SREBF1-Mediated Lipogenic Pathway.
Volume: 67
Issue: 6
Pages: 1113-1127
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Publication
20061376 | J:165953
First Author: Shinohara M
Year: 2010
Journal: J Biol Chem
Title: Silencing glycogen synthase kinase-3beta inhibits acetaminophen hepatotoxicity and attenuates JNK activation and loss of glutamate cysteine ligase and myeloid cell leukemia sequence 1.
Volume: 285
Issue: 11
Pages: 8244-55
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Publication
9582278 | J:48216
First Author: Günes C
Year: 1998
Journal: EMBO J
Title: Embryonic lethality and liver degeneration in mice lacking the metal-responsive transcriptional activator MTF-1.
Volume: 17
Issue: 10
Pages: 2846-54
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7578676 | J:29012
First Author: Harvey MB
Year: 1995
Journal: Biol Reprod
Title: Expression of genes encoding antioxidant enzymes in preimplantation mouse and cow embryos and primary bovine oviduct cultures employed for embryo coculture.
Volume: 53
Issue: 3
Pages: 532-40
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10421798 | J:57158
First Author: El Mouatassim S
Year: 1999
Journal: Mol Hum Reprod
Title: Expression of genes encoding antioxidant enzymes in human and mouse oocytes during the final stages of maturation.
Volume: 5
Issue: 8
Pages: 720-5
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Publication
36243294 | J:330375
 
First Author: Dionne G
Year: 2022
Journal: Gene Expr Patterns
Title: Expression and localization of NRF2/Keap1 signalling pathway genes in mouse preimplantation embryos exposed to free fatty acids.
Volume: 46
Pages: 119281
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Publication
21554947 | J:172598
First Author: Brewer AC
Year: 2011
Journal: Free Radic Biol Med
Title: Nox4 regulates Nrf2 and glutathione redox in cardiomyocytes in vivo.
Volume: 51
Issue: 1
Pages: 205-15
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9441766 | J:45558
First Author: Yamazaki K
Year: 1997
Journal: Genomics
Title: Assignment of a disintegrin and metalloproteinase domain 10 (Adam10) gene to mouse chromosome 9.
Volume: 46
Issue: 3
Pages: 528-9
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23237955 | J:191045
First Author: Huebner AJ
Year: 2012
Journal: Dev Cell
Title: Amniotic fluid activates the nrf2/keap1 pathway to repair an epidermal barrier defect in utero.
Volume: 23
Issue: 6
Pages: 1238-46
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Publication
20404090 | J:162676
First Author: Taguchi K
Year: 2010
Journal: Mol Cell Biol
Title: Genetic analysis of cytoprotective functions supported by graded expression of Keap1.
Volume: 30
Issue: 12
Pages: 3016-26
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Publication
30753104 | J:287221
First Author: Partearroyo T
Year: 2019
Journal: FASEB J
Title: Betaine-homocysteine S-methyltransferase deficiency causes increased susceptibility to noise-induced hearing loss associated with plasma hyperhomocysteinemia.
Volume: 33
Issue: 5
Pages: 5942-5956
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Publication
20300111 | J:175212
First Author: Meixner A
Year: 2010
Journal: Cell Death Differ
Title: Jun and JunD-dependent functions in cell proliferation and stress response.
Volume: 17
Issue: 9
Pages: 1409-19
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27125672 | J:232562
First Author: Dayton TL
Year: 2016
Journal: Genes Dev
Title: Germline loss of PKM2 promotes metabolic distress and hepatocellular carcinoma.
Volume: 30
Issue: 9
Pages: 1020-33
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Publication
34359856 | J:314222
 
First Author: Celaya AM
Year: 2021
Journal: Cells
Title: IGF-1 Haploinsufficiency Causes Age-Related Chronic Cochlear Inflammation and Increases Noise-Induced Hearing Loss.
Volume: 10
Issue: 7
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Publication
26199344 | J:318865
First Author: Zheng B
Year: 2015
Journal: Mol Cell Proteomics
Title: Quantitative Proteomics Reveals the Essential Roles of Stromal Interaction Molecule 1 (STIM1) in the Testicular Cord Formation in Mouse Testis.
Volume: 14
Issue: 10
Pages: 2682-91
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Publication
31220272 | J:277277
First Author: Zieman AG
Year: 2019
Journal: Hum Mol Genet
Title: Altered keratinocyte differentiation is an early driver of keratin mutation-based palmoplantar keratoderma.
Volume: 28
Issue: 13
Pages: 2255-2270
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30938680 | J:274697
   
First Author: Celaya AM
Year: 2019
Journal: Elife
Title: Deficit of mitogen-activated protein kinase phosphatase 1 (DUSP1) accelerates progressive hearing loss.
Volume: 8
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9811942 | J:50869
First Author: Ko MS
Year: 1998
Journal: Hum Mol Genet
Title: Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome.
Volume: 7
Issue: 12
Pages: 1967-78
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Publication
19521500 | J:149737
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
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19521566 | J:177549
First Author: Willnow T
Year: 2005
Journal: Organogenesis
Title: The European renal genome project: an integrated approach towards understanding the genetics of kidney development and disease.
Volume: 2
Issue: 2
Pages: 42-7
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Publication
- | J:175295
     
First Author: Mouse Genome Informatics and the Wellcome Trust Sanger Institute Mouse Genetics Project (MGP)
Year: 2011
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the Wellcome Trust Sanger Institute (WTSI) Mouse Resources Portal
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
- | J:24194
     
First Author: The Jackson Laboratory Backcross DNA Panel Mapping Resource
Year: 1999
Journal: Database Release
Title: JAX BSS Panel Mapping Data
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30973865 | J:274872
First Author: Ingham NJ
Year: 2019
Journal: PLoS Biol
Title: Mouse screen reveals multiple new genes underlying mouse and human hearing loss.
Volume: 17
Issue: 4
Pages: e3000194
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10725249 | J:60984
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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Publication
14681479 | J:122989
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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