Type |
Details |
Score |
Publication |
First Author: |
Sugiyama D |
Year: |
2013 |
Journal: |
Mech Dev |
Title: |
TGF-beta-1 up-regulates extra-cellular matrix production in mouse hepatoblasts. |
Volume: |
130 |
Issue: |
2-3 |
Pages: |
195-206 |
|
•
•
•
•
•
|
Publication |
First Author: |
Maddala R |
Year: |
2015 |
Journal: |
Dev Biol |
Title: |
Rap1 GTPase is required for mouse lens epithelial maintenance and morphogenesis. |
Volume: |
406 |
Issue: |
1 |
Pages: |
74-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bernier-Latmani J |
Year: |
2015 |
Journal: |
J Clin Invest |
Title: |
DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport. |
Volume: |
125 |
Issue: |
12 |
Pages: |
4572-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mailleux AA |
Year: |
2007 |
Journal: |
Dev Cell |
Title: |
BIM regulates apoptosis during mammary ductal morphogenesis, and its absence reveals alternative cell death mechanisms. |
Volume: |
12 |
Issue: |
2 |
Pages: |
221-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chiang YJ |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
CBAP functions as a novel component in chemokine-induced ZAP70-mediated T-cell adhesion and migration. |
Volume: |
8 |
Issue: |
4 |
Pages: |
e61761 |
|
•
•
•
•
•
|
Publication |
First Author: |
RitiƩ L |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Abnormal Wnt and PI3Kinase signaling in the malformed intestine of lama5 deficient mice. |
Volume: |
7 |
Issue: |
5 |
Pages: |
e37710 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chaen T |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Estrogen-dependent uterine secretion of osteopontin activates blastocyst adhesion competence. |
Volume: |
7 |
Issue: |
11 |
Pages: |
e48933 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gao G |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
Isthmin-1 (Ism1) modulates renal branching morphogenesis and mesenchyme condensation during early kidney development. |
Volume: |
14 |
Issue: |
1 |
Pages: |
2378 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aszodi A |
Year: |
2003 |
Journal: |
Genes Dev |
Title: |
Beta1 integrins regulate chondrocyte rotation, G1 progression, and cytokinesis. |
Volume: |
17 |
Issue: |
19 |
Pages: |
2465-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nantie LB |
Year: |
2018 |
Journal: |
Development |
Title: |
Lats1/2 inactivation reveals Hippo function in alveolar type I cell differentiation during lung transition to air breathing. |
Volume: |
145 |
Issue: |
21 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ayyangar U |
Year: |
2024 |
Journal: |
EMBO J |
Title: |
Metabolic rewiring of macrophages by epidermal-derived lactate promotes sterile inflammation in the murine skin. |
Volume: |
43 |
Issue: |
7 |
Pages: |
1113-1134 |
|
•
•
•
•
•
|
Publication |
First Author: |
Collins TN |
Year: |
2018 |
Journal: |
Elife |
Title: |
Crk proteins transduce FGF signaling to promote lens fiber cell elongation. |
Volume: |
7 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Gao J |
Year: |
2008 |
Journal: |
Genes Dev |
Title: |
Laminin-511 is an epithelial message promoting dermal papilla development and function during early hair morphogenesis. |
Volume: |
22 |
Issue: |
15 |
Pages: |
2111-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Reyahi A |
Year: |
2015 |
Journal: |
Dev Cell |
Title: |
Foxf2 Is Required for Brain Pericyte Differentiation and Development and Maintenance of the Blood-Brain Barrier. |
Volume: |
34 |
Issue: |
1 |
Pages: |
19-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Besschetnova TY |
Year: |
2015 |
Journal: |
Matrix Biol |
Title: |
Regulatory mechanisms of anthrax toxin receptor 1-dependent vascular and connective tissue homeostasis. |
Volume: |
42 |
|
Pages: |
56-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brody MJ |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
Ablation of the cardiac-specific gene leucine-rich repeat containing 10 (Lrrc10) results in dilated cardiomyopathy. |
Volume: |
7 |
Issue: |
12 |
Pages: |
e51621 |
|
•
•
•
•
•
|
Publication |
First Author: |
Petzold KM |
Year: |
2013 |
Journal: |
Development |
Title: |
Rho signalling restriction by the RhoGAP Stard13 integrates growth and morphogenesis in the pancreas. |
Volume: |
140 |
Issue: |
1 |
Pages: |
126-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hirano M |
Year: |
2008 |
Journal: |
J Cell Biol |
Title: |
EPB41L5 functions to post-transcriptionally regulate cadherin and integrin during epithelial-mesenchymal transition. |
Volume: |
182 |
Issue: |
6 |
Pages: |
1217-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tan J |
Year: |
2017 |
Journal: |
Neural Dev |
Title: |
Lacking of palladin leads to multiple cellular events changes which contribute to NTD. |
Volume: |
12 |
Issue: |
1 |
Pages: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Romano RA |
Year: |
2012 |
Journal: |
Development |
Title: |
ĪNp63 knockout mice reveal its indispensable role as a master regulator of epithelial development and differentiation. |
Volume: |
139 |
Issue: |
4 |
Pages: |
772-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen SR |
Year: |
2013 |
Journal: |
BMC Biol |
Title: |
Disruption of genital ridge development causes aberrant primordial germ cell proliferation but does not affect their directional migration. |
Volume: |
11 |
|
Pages: |
22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yang N |
Year: |
2022 |
Journal: |
J Dent Res |
Title: |
Adamts18 Deficiency Causes Spontaneous SMG Fibrogenesis in Adult Mice. |
Volume: |
101 |
Issue: |
2 |
Pages: |
226-234 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
1994 |
Journal: |
Mamm Genome |
Title: |
Genetic mapping of 40 cDNA clones on the mouse genome by PCR. |
Volume: |
5 |
Issue: |
6 |
Pages: |
349-55 |
|
•
•
•
•
•
|
Publication |
First Author: |
Heinrich A |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Distinct Roles for Rac1 in Sertoli Cell Function during Testicular Development and Spermatogenesis. |
Volume: |
31 |
Issue: |
2 |
Pages: |
107513 |
|
•
•
•
•
•
|
Publication |
First Author: |
Franco CA |
Year: |
2008 |
Journal: |
Dev Cell |
Title: |
Serum response factor is required for sprouting angiogenesis and vascular integrity. |
Volume: |
15 |
Issue: |
3 |
Pages: |
448-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morse HC 3rd |
Year: |
1992 |
Journal: |
J Immunol |
Title: |
Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells. |
Volume: |
149 |
Issue: |
10 |
Pages: |
3129-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ghai R |
Year: |
2013 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structural basis for endosomal trafficking of diverse transmembrane cargos by PX-FERM proteins. |
Volume: |
110 |
Issue: |
8 |
Pages: |
E643-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Papin J |
Year: |
2004 |
Journal: |
Curr Opin Biotechnol |
Title: |
Bioinformatics and cellular signaling. |
Volume: |
15 |
Issue: |
1 |
Pages: |
78-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Neidhardt L |
Year: |
2000 |
Journal: |
Mech Dev |
Title: |
Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos. |
Volume: |
98 |
Issue: |
1-2 |
Pages: |
77-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Koss M |
Year: |
2012 |
Journal: |
Dev Cell |
Title: |
Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module. |
Volume: |
22 |
Issue: |
5 |
Pages: |
913-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Freeman TC |
Year: |
1998 |
Journal: |
MGI Direct Data Submission |
Title: |
Expression Mapping of Mouse Genes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2001 |
|
Title: |
Gene Ontology Annotation by the MGI Curatorial Staff |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
Journal: |
Database Download |
Title: |
Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen J |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
Volume: |
100 |
Issue: |
17 |
Pages: |
9918-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
Issue: |
1 |
Pages: |
278-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bedogni F |
Year: |
2021 |
Journal: |
Front Mol Neurosci |
Title: |
Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. |
Volume: |
14 |
|
Pages: |
686034 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6197250 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2018-09-10 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754420 |
Pattern: |
Not Specified |
Stage: |
TS20 |
Assay Id: |
MGI:6197274 |
Age: |
embryonic day 11.5 |
|
Note: |
Co-localized with Itgb1 in neuroepithelial cells. |
Specimen Label: |
S6 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:7431095 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2023-02-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3268828 |
Pattern: |
Regionally restricted |
Stage: |
TS28 |
Assay Id: |
MGI:7431102 |
Age: |
postnatal adult |
Image: |
2C (right) |
Note: |
Expression co-localized with Itgb1 in costamere at sarcolemmal membrane. |
Specimen Label: |
2C (right) |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
Allele |
Name: |
integrin beta 1 (fibronectin receptor beta); endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Humanized sequence, Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
Allele |
Name: |
integrin beta 1 (fibronectin receptor beta); targeted mutation 3, Reinhard Fassler |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout, Reporter |
|
•
•
•
•
•
|
Allele |
Name: |
integrin beta 1 (fibronectin receptor beta); targeted mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
integrin beta 1 (fibronectin receptor beta); targeted mutation 1.1, Elaine Fuchs |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Itgb1/Itgb1 |
Background: |
involves: 129X1/SvJ |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
88
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
490
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
528
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
396
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
SCAI is a transcriptional cofactor and tumour suppressor that suppresses MKL1-induced SRF transcriptional activity. It may function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1 []. |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Itgb1/Itgb1 |
Background: |
involves: 129S1/Sv * 129X1/SvJ |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
606
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents protein SCAI from metazoans and plants. SCAI is a transcriptional cofactor and tumour suppressor that suppresses MKL1-induced SRF transcriptional activity. It may function in the RHOA-DIAPH1 signal transduction pathway and regulate cell migration through transcriptional regulation of ITGB1 []. |
|
•
•
•
•
•
|
Allele |
Name: |
integrin beta 1 (fibronectin receptor beta); targeted mutation 5.1, Reinhard Fassler |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Itgb1/Itgb1 |
Background: |
involves: 129X1/SvJ |
Zygosity: |
ht |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Allele |
Name: |
integrin beta 3; targeted mutation 2, Ararat J Ablooglu |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Genotype |
Symbol: |
Itgb1/Itgb1 |
Background: |
involves: 129S1/Sv * 129X1/SvJ |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Itgb3/Itgb3 |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Itgb1/Itgb1 Tg(Ttr-cre)1Hadj/? |
Background: |
involves: 129X1/SvJ * C57BL/6J * CBA/J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|