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Search results 101 to 200 out of 1144 for Pkd1

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Type Details Score
Publication
29875161 | J:267093
First Author: Yanda MK
Year: 2018
Journal: J Biol Chem
Title: A potential strategy for reducing cysts in autosomal dominant polycystic kidney disease with a CFTR corrector.
Volume: 293
Issue: 29
Pages: 11513-11526
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Publication
30332302 | J:286671
First Author: Kim DY
Year: 2019
Journal: FASEB J
Title: Impact of miR-192 and miR-194 on cyst enlargement through EMT in autosomal dominant polycystic kidney disease.
Volume: 33
Issue: 2
Pages: 2870-2884
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Publication
29931260 | J:266901
First Author: Parnell SC
Year: 2018
Journal: Hum Mol Genet
Title: A mutation affecting polycystin-1 mediated heterotrimeric G-protein signaling causes PKD.
Volume: 27
Issue: 19
Pages: 3313-3324
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Publication
17965720 | J:141463
First Author: Piontek K
Year: 2007
Journal: Nat Med
Title: A critical developmental switch defines the kinetics of kidney cyst formation after loss of Pkd1.
Volume: 13
Issue: 12
Pages: 1490-5
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Publication
27077126 | J:260415
 
First Author: Menezes LF
Year: 2016
Journal: EBioMedicine
Title: Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease.
Volume: 5
Pages: 183-92
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Publication
21345977 | J:280014
First Author: Leonhard WN
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: Curcumin inhibits cystogenesis by simultaneous interference of multiple signaling pathways: in vivo evidence from a Pkd1-deletion model.
Volume: 300
Issue: 5
Pages: F1193-202
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Publication
19401297 | J:150029
First Author: Happé H
Year: 2009
Journal: Hum Mol Genet
Title: Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways.
Volume: 18
Issue: 14
Pages: 2532-42
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Publication
38070582 | J:344168
First Author: Yasinoglu SA
Year: 2024
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Transcriptomic profiling of Polycystic Kidney Disease identifies paracrine factors in the early cyst microenvironment.
Volume: 1870
Issue: 2
Pages: 166987
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Publication
11689485 | J:72627
First Author: Lu W
Year: 2001
Journal: Hum Mol Genet
Title: Comparison of Pkd1-targeted mutants reveals that loss of polycystin-1 causes cystogenesis and bone defects.
Volume: 10
Issue: 21
Pages: 2385-96
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Publication
34262092 | J:328513
First Author: Sousa MV
Year: 2021
Journal: Sci Rep
Title: Smoking accelerates renal cystic disease and worsens cardiac phenotype in Pkd1-deficient mice.
Volume: 11
Issue: 1
Pages: 14443
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Publication
23858461 | J:198775
First Author: Seeger-Nukpezah T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inhibiting the HSP90 chaperone slows cyst growth in a mouse model of autosomal dominant polycystic kidney disease.
Volume: 110
Issue: 31
Pages: 12786-91
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Publication
30042193 | J:293549
First Author: Yang Y
Year: 2018
Journal: J Am Soc Nephrol
Title: Interactions between Macrophages and Cyst-Lining Epithelial Cells Promote Kidney Cyst Growth in Pkd1-Deficient Mice.
Volume: 29
Issue: 9
Pages: 2310-2325
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Publication
24472557 | J:219152
First Author: Rowe I
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Impaired glomerulogenesis and endothelial cell migration in Pkd1-deficient renal organ cultures.
Volume: 444
Issue: 4
Pages: 473-9
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Publication
23466997 | J:277132
First Author: Happé H
Year: 2013
Journal: Kidney Int
Title: Cyst expansion and regression in a mouse model of polycystic kidney disease.
Volume: 83
Issue: 6
Pages: 1099-108
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Publication
17656674 | J:134890
First Author: Hassane S
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Pathogenic sequence for dissecting aneurysm formation in a hypomorphic polycystic kidney disease 1 mouse model.
Volume: 27
Issue: 10
Pages: 2177-83
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Publication
33705824 | J:324272
First Author: Arroyo J
Year: 2021
Journal: Kidney Int
Title: The genetic background significantly impacts the severity of kidney cystic disease in the Pkd1RC/RC mouse model of autosomal dominant polycystic kidney disease.
Volume: 99
Issue: 6
Pages: 1392-1407
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Publication
18385427 | J:323261
First Author: Yang B
Year: 2008
Journal: J Am Soc Nephrol
Title: Small-molecule CFTR inhibitors slow cyst growth in polycystic kidney disease.
Volume: 19
Issue: 7
Pages: 1300-10
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Publication
18566106 | J:138273
First Author: Battini L
Year: 2008
Journal: Hum Mol Genet
Title: Loss of polycystin-1 causes centrosome amplification and genomic instability.
Volume: 17
Issue: 18
Pages: 2819-33
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Publication
28993480 | J:257362
     
First Author: Ishimoto Y
Year: 2017
Journal: Mol Cell Biol
Title: Mitochondrial Abnormality Facilitates Cyst Formation in Autosomal Dominant Polycystic Kidney Disease.
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Publication
32239723 | J:307491
First Author: Cassina L
Year: 2020
Journal: FASEB J
Title: Increased mitochondrial fragmentation in polycystic kidney disease acts as a modifier of disease progression.
Volume: 34
Issue: 5
Pages: 6493-6507
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Publication
20808796 | J:164014
First Author: Woodward OM
Year: 2010
Journal: PLoS One
Title: Identification of a polycystin-1 cleavage product, P100, that regulates store operated Ca entry through interactions with STIM1.
Volume: 5
Issue: 8
Pages: e12305
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Publication
21900881 | J:196564
First Author: Fan LX
Year: 2012
Journal: Kidney Int
Title: Inhibition of histone deacetylases targets the transcription regulator Id2 to attenuate cystic epithelial cell proliferation.
Volume: 81
Issue: 1
Pages: 76-85
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Publication
17671167 | J:128281
First Author: Boca M
Year: 2007
Journal: Mol Biol Cell
Title: Polycystin-1 induces cell migration by regulating phosphatidylinositol 3-kinase-dependent cytoskeletal rearrangements and GSK3beta-dependent cell cell mechanical adhesion.
Volume: 18
Issue: 10
Pages: 4050-61
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Publication
21821671 | J:176682
First Author: Takakura A
Year: 2011
Journal: Hum Mol Genet
Title: Pyrimethamine inhibits adult polycystic kidney disease by modulating STAT signaling pathways.
Volume: 20
Issue: 21
Pages: 4143-54
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Publication
20814903 | J:164355
First Author: Wang E
Year: 2010
Journal: J Pathol
Title: Progressive renal distortion by multiple cysts in transgenic mice expressing artificial microRNAs against Pkd1.
Volume: 222
Issue: 3
Pages: 238-48
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Publication
21642537 | J:245263
First Author: Zhu J
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Structural model of the TRPP2/PKD1 C-terminal coiled-coil complex produced by a combined computational and experimental approach.
Volume: 108
Issue: 25
Pages: 10133-8
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Publication
9140045 | J:40260
First Author: Geng L
Year: 1997
Journal: Am J Physiol
Title: Distribution and developmentally regulated expression of murine polycystin.
Volume: 272
Issue: 4 Pt 2
Pages: F451-9
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Publication
9350642 | J:44584
First Author: Griffin MD
Year: 1997
Journal: Kidney Int
Title: Expression of polycystin in mouse metanephros and extra-metanephric tissues.
Volume: 52
Issue: 5
Pages: 1196-205
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Publication
17980165 | J:133252
First Author: Li X
Year: 2008
Journal: Biochim Biophys Acta
Title: Protein kinase X (PRKX) can rescue the effects of polycystic kidney disease-1 gene (PKD1) deficiency.
Volume: 1782
Issue: 1
Pages: 1-9
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Publication
28007903 | J:241440
First Author: Zhu P
Year: 2017
Journal: Hum Mol Genet
Title: Autophagy activators suppress cystogenesis in an autosomal dominant polycystic kidney disease model.
Volume: 26
Issue: 1
Pages: 158-172
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Publication
35955634 | J:328219
 
First Author: Chang MY
Year: 2022
Journal: Int J Mol Sci
Title: Effects of Suramin on Polycystic Kidney Disease in a Mouse Model of Polycystin-1 Deficiency.
Volume: 23
Issue: 15
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Publication
29483507 | J:259698
First Author: Flowers EM
Year: 2018
Journal: Nat Commun
Title: Lkb1 deficiency confers glutamine dependency in polycystic kidney disease.
Volume: 9
Issue: 1
Pages: 814
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Publication
29925518 | J:317608
 
First Author: Viau A
Year: 2018
Journal: EMBO J
Title: Cilia-localized LKB1 regulates chemokine signaling, macrophage recruitment, and tissue homeostasis in the kidney.
Volume: 37
Issue: 15
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Publication
21389971 | J:195613
First Author: Miller MM
Year: 2011
Journal: Kidney Int
Title: T-cell factor/β-catenin activity is suppressed in two different models of autosomal dominant polycystic kidney disease.
Volume: 80
Issue: 2
Pages: 146-53
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Publication
23129748 | J:190972
First Author: Ittner A
Year: 2012
Journal: J Exp Med
Title: Regulation of PTEN activity by p38δ-PKD1 signaling in neutrophils confers inflammatory responses in the lung.
Volume: 209
Issue: 12
Pages: 2229-46
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Publication
26931735 | J:236345
 
First Author: Pema M
Year: 2016
Journal: Nat Commun
Title: mTORC1-mediated inhibition of polycystin-1 expression drives renal cyst formation in tuberous sclerosis complex.
Volume: 7
Pages: 10786
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Publication
19255143 | J:148419
First Author: Distefano G
Year: 2009
Journal: Mol Cell Biol
Title: Polycystin-1 regulates extracellular signal-regulated kinase-dependent phosphorylation of tuberin to control cell size through mTOR and its downstream effectors S6K and 4EBP1.
Volume: 29
Issue: 9
Pages: 2359-71
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Publication
18579360 | J:140779
First Author: Kolpakova-Hart E
Year: 2008
Journal: Matrix Biol
Title: Col2-Cre recombinase is co-expressed with endogenous type II collagen in embryonic renal epithelium and drives development of polycystic kidney disease following inactivation of ciliary genes.
Volume: 27
Issue: 6
Pages: 505-12
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DO Term
DOID:0110858 | polycystic kidney disease 1
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Publication
15548533 | J:96951
First Author: Murakami M
Year: 2005
Journal: J Biol Chem
Title: Genomic organization and functional analysis of murine PKD2L1.
Volume: 280
Issue: 7
Pages: 5626-35
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Publication
25139996 | J:216403
First Author: Nikonova AS
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Nedd9 restrains renal cystogenesis in Pkd1-/- mice.
Volume: 111
Issue: 35
Pages: 12859-64
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Publication
30209078 | J:293550
First Author: Cassini MF
Year: 2018
Journal: J Am Soc Nephrol
Title: Mcp1 Promotes Macrophage-Dependent Cyst Expansion in Autosomal Dominant Polycystic Kidney Disease.
Volume: 29
Issue: 10
Pages: 2471-2481
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Publication
29717938 | J:280706
First Author: Kipp KR
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Comparison of folate-conjugated rapamycin versus unconjugated rapamycin in an orthologous mouse model of polycystic kidney disease.
Volume: 315
Issue: 2
Pages: F395-F405
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Publication
28604386 | J:243943
First Author: Li LX
Year: 2017
Journal: J Clin Invest
Title: Lysine methyltransferase SMYD2 promotes cyst growth in autosomal dominant polycystic kidney disease.
Volume: 127
Issue: 7
Pages: 2751-2764
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Publication
28701314 | J:273564
First Author: Porath B
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Cux1 promotes cell proliferation and polycystic kidney disease progression in an ADPKD mouse model.
Volume: 313
Issue: 4
Pages: F1050-F1059
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Publication
31625572 | J:285775
First Author: Conduit SE
Year: 2020
Journal: Hum Mol Genet
Title: AKT signaling promotes DNA damage accumulation and proliferation in polycystic kidney disease.
Volume: 29
Issue: 1
Pages: 31-48
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Publication
27179075 | J:246270
First Author: Sroka R
Year: 2016
Journal: J Cell Sci
Title: Cortactin is a scaffolding platform for the E-cadherin adhesion complex and is regulated by protein kinase D1 phosphorylation.
Volume: 129
Issue: 12
Pages: 2416-29
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Publication
23064367 | J:193544
First Author: Hopp K
Year: 2012
Journal: J Clin Invest
Title: Functional polycystin-1 dosage governs autosomal dominant polycystic kidney disease severity.
Volume: 122
Issue: 11
Pages: 4257-73
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Publication
24203696 | J:206980
First Author: Zhou X
Year: 2014
Journal: Hum Mol Genet
Title: SIRT2 regulates ciliogenesis and contributes to abnormal centrosome amplification caused by loss of polycystin-1.
Volume: 23
Issue: 6
Pages: 1644-55
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Publication
33490963 | J:346469
First Author: Zimmerman KA
Year: 2020
Journal: Kidney360
Title: Interferon Regulatory Factor-5 in Resident Macrophage Promotes Polycystic Kidney Disease.
Volume: 1
Issue: 3
Pages: 179-190
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Publication
29202470 | J:258407
First Author: Xiao Z
Year: 2018
Journal: J Clin Invest
Title: Polycystin-1 interacts with TAZ to stimulate osteoblastogenesis and inhibit adipogenesis.
Volume: 128
Issue: 1
Pages: 157-174
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Publication
32185407 | J:322927
First Author: Cabrita I
Year: 2020
Journal: J Mol Med (Berl)
Title: TMEM16A drives renal cyst growth by augmenting Ca2+ signaling in M1 cells.
Volume: 98
Issue: 5
Pages: 659-671
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Publication
30768374 | J:292326
First Author: Wang W
Year: 2019
Journal: FASEB J
Title: Aquaporin-3 deficiency slows cyst enlargement in experimental mouse models of autosomal dominant polycystic kidney disease.
Volume: 33
Issue: 5
Pages: 6185-6196
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Publication
31589480 | J:293673
First Author: Chen YC
Year: 2019
Journal: FASEB J
Title: Prothymosin α promotes STAT3 acetylation to induce cystogenesis in Pkd1-deficient mice.
Volume: 33
Issue: 11
Pages: 13051-13061
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Publication
29767557 | J:279824
First Author: Verschuren EHJ
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Polycystin-1 dysfunction impairs electrolyte and water handling in a renal precystic mouse model for ADPKD.
Volume: 315
Issue: 3
Pages: F537-F546
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Publication
25531116 | J:226866
First Author: Le Corre S
Year: 2015
Journal: Nephron
Title: Cystic gene dosage influences kidney lesions after nephron reduction.
Volume: 129
Issue: 1
Pages: 42-51
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Publication
24767998 | J:211806
First Author: Outeda P
Year: 2014
Journal: Cell Rep
Title: Polycystin signaling is required for directed endothelial cell migration and lymphatic development.
Volume: 7
Issue: 3
Pages: 634-44
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Publication
22832196 | J:323538
First Author: Peyronnet R
Year: 2012
Journal: Cell Rep
Title: Mechanoprotection by polycystins against apoptosis is mediated through the opening of stretch-activated K(2P) channels.
Volume: 1
Issue: 3
Pages: 241-50
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Publication
10770959 | J:169812
First Author: Foggensteiner L
Year: 2000
Journal: J Am Soc Nephrol
Title: Cellular and subcellular distribution of polycystin-2, the protein product of the PKD2 gene.
Volume: 11
Issue: 5
Pages: 814-27
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Publication
27020852 | J:293509
First Author: Leonhard WN
Year: 2016
Journal: J Am Soc Nephrol
Title: Inhibition of Activin Signaling Slows Progression of Polycystic Kidney Disease.
Volume: 27
Issue: 12
Pages: 3589-3599
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Publication
35229718 | J:327479
   
First Author: MacKay CE
Year: 2022
Journal: Elife
Title: A plasma membrane-localized polycystin-1/polycystin-2 complex in endothelial cells elicits vasodilation.
Volume: 11
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Publication
25574838 | J:220561
First Author: Gainullin VG
Year: 2015
Journal: J Clin Invest
Title: Polycystin-1 maturation requires polycystin-2 in a dose-dependent manner.
Volume: 125
Issue: 2
Pages: 607-20
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Publication
25503729 | J:283211
First Author: Hopp K
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Effects of hydration in rats and mice with polycystic kidney disease.
Volume: 308
Issue: 3
Pages: F261-6
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Publication
29401581 | J:273819
First Author: Nikonova AS
Year: 2018
Journal: FASEB J
Title: Ganetespib limits ciliation and cystogenesis in autosomal-dominant polycystic kidney disease (ADPKD).
Volume: 32
Issue: 5
Pages: 2735-2746
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Publication
28615245 | J:281864
First Author: Ye H
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: The regulatory 1α subunit of protein kinase A modulates renal cystogenesis.
Volume: 313
Issue: 3
Pages: F677-F686
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Publication
25365220 | J:219409
First Author: Cai Y
Year: 2014
Journal: J Clin Invest
Title: Altered trafficking and stability of polycystins underlie polycystic kidney disease.
Volume: 124
Issue: 12
Pages: 5129-44
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Publication
10655152 | J:60518
First Author: Wu G
Year: 2000
Journal: Mol Genet Metab
Title: Molecular genetics and mechanism of autosomal dominant polycystic kidney disease.
Volume: 69
Issue: 1
Pages: 1-15
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Publication
23209428 | J:194672
First Author: Menezes LF
Year: 2012
Journal: PLoS Genet
Title: Network analysis of a Pkd1-mouse model of autosomal dominant polycystic kidney disease identifies HNF4α as a disease modifier.
Volume: 8
Issue: 11
Pages: e1003053
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Publication
34473378 | J:317723
First Author: Talbi K
Year: 2021
Journal: FASEB J
Title: The chloride channel CFTR is not required for cyst growth in an ADPKD mouse model.
Volume: 35
Issue: 10
Pages: e21897
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Publication
28077374 | J:283128
First Author: Streets AJ
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: Parallel microarray profiling identifies ErbB4 as a determinant of cyst growth in ADPKD and a prognostic biomarker for disease progression.
Volume: 312
Issue: 4
Pages: F577-F588
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Publication
23390129 | J:194972
First Author: Streets AJ
Year: 2013
Journal: Hum Mol Genet
Title: Hyperphosphorylation of polycystin-2 at a critical residue in disease reveals an essential role for polycystin-1-regulated dephosphorylation.
Volume: 22
Issue: 10
Pages: 1924-39
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Publication
26289599 | J:270901
First Author: Jansson K
Year: 2015
Journal: J Membr Biol
Title: Ouabain Regulates CFTR-Mediated Anion Secretion and Na,K-ATPase Transport in ADPKD Cells.
Volume: 248
Issue: 6
Pages: 1145-57
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Publication
23778143 | J:201423
First Author: Zhou X
Year: 2013
Journal: J Clin Invest
Title: Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney disease.
Volume: 123
Issue: 7
Pages: 3084-98
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Publication
17082250 | J:117762
First Author: Stayner C
Year: 2006
Journal: Hum Mol Genet
Title: Pax2 gene dosage influences cystogenesis in autosomal dominant polycystic kidney disease.
Volume: 15
Issue: 24
Pages: 3520-8
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Publication
16905538 | J:116968
First Author: Xiao Z
Year: 2006
Journal: J Biol Chem
Title: Cilia-like structures and polycystin-1 in osteoblasts/osteocytes and associated abnormalities in skeletogenesis and Runx2 expression.
Volume: 281
Issue: 41
Pages: 30884-95
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Publication
16931520 | J:117400
First Author: Van Bodegom D
Year: 2006
Journal: J Biol Chem
Title: The polycystic kidney disease-1 gene is a target for p53-mediated transcriptional repression.
Volume: 281
Issue: 42
Pages: 31234-44
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Publication
11901144 | J:77086
First Author: Newby LJ
Year: 2002
Journal: J Biol Chem
Title: Identification, characterization, and localization of a novel kidney polycystin-1-polycystin-2 complex.
Volume: 277
Issue: 23
Pages: 20763-73
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Publication
8828041 | J:33617
First Author: Burn TC
Year: 1996
Journal: Genome Res
Title: Generation of a transcriptional map for a 700-kb region surrounding the polycystic kidney disease type 1 (PKD1) and tuberous sclerosis type 2 (TSC2) disease genes on human chromosome 16p3.3.
Volume: 6
Issue: 6
Pages: 525-37
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Publication
24459142 | J:317220
First Author: Cebotaru V
Year: 2014
Journal: J Biol Chem
Title: Polycystin-1 negatively regulates Polycystin-2 expression via the aggresome/autophagosome pathway.
Volume: 289
Issue: 10
Pages: 6404-6414
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Publication
24153433 | J:206193
 
First Author: Castelli M
Year: 2013
Journal: Nat Commun
Title: Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.
Volume: 4
Pages: 2658
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Publication
25999403 | J:229242
 
First Author: Saigusa T
Year: 2015
Journal: Physiol Rep
Title: Activation of the intrarenal renin-angiotensin-system in murine polycystic kidney disease.
Volume: 3
Issue: 5
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Publication
12514735 | J:81443
First Author: Nauli SM
Year: 2003
Journal: Nat Genet
Title: Polycystins 1 and 2 mediate mechanosensation in the primary cilium of kidney cells.
Volume: 33
Issue: 2
Pages: 129-37
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Publication
18263604 | J:135301
First Author: Shibazaki S
Year: 2008
Journal: Hum Mol Genet
Title: Cyst formation and activation of the extracellular regulated kinase pathway after kidney specific inactivation of Pkd1.
Volume: 17
Issue: 11
Pages: 1505-16
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Publication
19321600 | J:148543
First Author: Bonnet CS
Year: 2009
Journal: Hum Mol Genet
Title: Defects in cell polarity underlie TSC and ADPKD-associated cystogenesis.
Volume: 18
Issue: 12
Pages: 2166-76
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Publication
34199520 | J:321356
 
First Author: Talbi K
Year: 2021
Journal: Int J Mol Sci
Title: Gender-Dependent Phenotype in Polycystic Kidney Disease Is Determined by Differential Intracellular Ca2+ Signals.
Volume: 22
Issue: 11
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24071006 | J:299121
First Author: Liu D
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Journal: J Am Soc Nephrol
Title: A Pkd1-Fbn1 genetic interaction implicates TGF-β signaling in the pathogenesis of vascular complications in autosomal dominant polycystic kidney disease.
Volume: 25
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28104302 | J:314819
First Author: Fragiadaki M
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Title: STAT5 drives abnormal proliferation in autosomal dominant polycystic kidney disease.
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Title: Urine Fetuin-A is a biomarker of autosomal dominant polycystic kidney disease progression.
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Title: Progesterone induced mesenchymal differentiation and rescued cystic dilation of renal tubules of Pkd1(-/-) mice.
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Title: HDAC6 regulates epidermal growth factor receptor (EGFR) endocytic trafficking and degradation in renal epithelial cells.
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Title: Nephron-Specific Disruption of Polycystin-1 Induces Cyclooxygenase-2-Mediated Blood Pressure Reduction Independent of Cystogenesis.
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Title: Tulp3 Is a Ciliary Trafficking Gene that Regulates Polycystic Kidney Disease.
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Title: A RhoA-YAP-c-Myc signaling axis promotes the development of polycystic kidney disease.
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Title: Long noncoding RNA Hoxb3os is dysregulated in autosomal dominant polycystic kidney disease and regulates mTOR signaling.
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