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Search results 1 to 100 out of 436 for Tsc2

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Category: Publication
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Type Details Score
Publication
17245776 | J:121748
First Author: Hernandez O
Year: 2007
Journal: Genesis
Title: Generation of a conditional disruption of the Tsc2 gene.
Volume: 45
Issue: 2
Pages: 101-6
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Publication
29509898 | J:261762
First Author: Ogórek B
Year: 2018
Journal: Hum Mol Genet
Title: TSC2 regulates microRNA biogenesis via mTORC1 and GSK3β.
Volume: 27
Issue: 9
Pages: 1654-1663
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Publication
30700906 | J:286196
First Author: Ranek MJ
Year: 2019
Journal: Nature
Title: PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress.
Volume: 566
Issue: 7743
Pages: 264-269
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Publication
23604129 | J:309778
First Author: Guenther GG
Year: 2014
Journal: Oncogene
Title: Loss of TSC2 confers resistance to ceramide and nutrient deprivation.
Volume: 33
Issue: 14
Pages: 1776-87
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Publication
8833243 | J:32010
First Author: Olsson PG
Year: 1996
Journal: Mamm Genome
Title: Expression and differential splicing of the mouse TSC2 homolog.
Volume: 7
Issue: 3
Pages: 212-5
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Publication
28695825 | J:257092
   
First Author: Klover PJ
Year: 2017
Journal: Elife
Title: Tsc2 disruption in mesenchymal progenitors results in tumors with vascular anomalies overexpressing Lgals3.
Volume: 6
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Publication
26868506 | J:236273
 
First Author: Demetriades C
Year: 2016
Journal: Nat Commun
Title: Lysosomal recruitment of TSC2 is a universal response to cellular stress.
Volume: 7
Pages: 10662
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Publication
19357198 | J:149326
First Author: Pollizzi K
Year: 2009
Journal: Hum Mol Genet
Title: A hypomorphic allele of Tsc2 highlights the role of TSC1/TSC2 in signaling to AKT and models mild human TSC2 alleles.
Volume: 18
Issue: 13
Pages: 2378-87
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Publication
22923640 | J:193437
First Author: Moir LM
Year: 2012
Journal: Am J Physiol Lung Cell Mol Physiol
Title: TSC2 modulates cell adhesion and migration via integrin-α1β1.
Volume: 303
Issue: 8
Pages: L703-10
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Publication
34253722 | J:307919
First Author: Alesi N
Year: 2021
Journal: Nat Commun
Title: TSC2 regulates lysosome biogenesis via a non-canonical RAGC and TFEB-dependent mechanism.
Volume: 12
Issue: 1
Pages: 4245
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Publication
20145209 | J:260298
First Author: Kuo HP
Year: 2010
Journal: Sci Signal
Title: ARD1 stabilization of TSC2 suppresses tumorigenesis through the mTOR signaling pathway.
Volume: 3
Issue: 108
Pages: ra9
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Publication
23359422 | J:195049
First Author: Fu C
Year: 2013
Journal: Genesis
Title: Conditional and domain-specific inactivation of the Tsc2 gene in neural progenitor cells.
Volume: 51
Issue: 4
Pages: 284-92
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Publication
24591652 | J:213670
First Author: Riddle RC
Year: 2014
Journal: Mol Cell Biol
Title: Tsc2 is a molecular checkpoint controlling osteoblast development and glucose homeostasis.
Volume: 34
Issue: 10
Pages: 1850-62
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Publication
15851026 | J:120197
First Author: Ma L
Year: 2005
Journal: Cell
Title: Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis.
Volume: 121
Issue: 2
Pages: 179-93
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Publication
35288456 | J:322886
 
First Author: Dunkerly-Eyring BL
Year: 2022
Journal: Life Sci Alliance
Title: Single serine on TSC2 exerts biased control over mTORC1 activation mediated by ERK1/2 but not Akt.
Volume: 5
Issue: 6
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Publication
25613864 | J:220337
First Author: Rozas NS
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Prolonging the survival of Tsc2 conditional knockout mice by glutamine supplementation.
Volume: 457
Issue: 4
Pages: 635-9
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Publication
36400753 | J:334189
First Author: Liu X
Year: 2022
Journal: Cell Death Dis
Title: Loss of myeloid Tsc2 predisposes to angiotensin II-induced aortic aneurysm formation in mice.
Volume: 13
Issue: 11
Pages: 972
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Publication
27542907 | J:250631
First Author: García-Aguilar A
Year: 2016
Journal: Biochim Biophys Acta
Title: TSC2 N-terminal lysine acetylation status affects to its stability modulating mTORC1 signaling and autophagy.
Volume: 1863
Issue: 11
Pages: 2658-2667
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Publication
36357396 | J:331095
First Author: Asrani K
Year: 2022
Journal: Nat Commun
Title: An mTORC1-mediated negative feedback loop constrains amino acid-induced FLCN-Rag activation in renal cells with TSC2 loss.
Volume: 13
Issue: 1
Pages: 6808
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Publication
36586433 | J:339842
 
First Author: Brazill JM
Year: 2023
Journal: Mol Metab
Title: Knockout of TSC2 in Nav1.8+ neurons predisposes to the onset of normal weight obesity.
Volume: 68
Pages: 101664
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Publication
23749404 | J:203971
First Author: Mietzsch U
Year: 2013
Journal: J Comp Neurol
Title: Comparative analysis of Tsc1 and Tsc2 single and double radial glial cell mutants.
Volume: 521
Issue: 16
Pages: 3817-31
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Publication
21886784 | J:176342
First Author: Koyanagi M
Year: 2011
Journal: PLoS One
Title: Ablation of TSC2 enhances insulin secretion by increasing the number of mitochondria through activation of mTORC1.
Volume: 6
Issue: 8
Pages: e23238
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Publication
26693177 | J:239993
 
First Author: Crowell B
Year: 2015
Journal: eNeuro
Title: Complex Neurological Phenotype in Mutant Mice Lacking Tsc2 in Excitatory Neurons of the Developing Forebrain(123).
Volume: 2
Issue: 6
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Publication
11741832 | J:73510
First Author: Nellist M
Year: 2001
Journal: Hum Mol Genet
Title: TSC2 missense mutations inhibit tuberin phosphorylation and prevent formation of the tuberin-hamartin complex.
Volume: 10
Issue: 25
Pages: 2889-98
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10827137 | J:62413
First Author: Pasumarthi KB
Year: 2000
Journal: Circ Res
Title: Enhanced cardiomyocyte DNA synthesis during myocardial hypertrophy in mice expressing a modified TSC2 transgene.
Volume: 86
Issue: 10
Pages: 1069-77
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23820898 | J:221228
First Author: Prizant H
Year: 2013
Journal: Mol Endocrinol
Title: Uterine-specific loss of Tsc2 leads to myometrial tumors in both the uterus and lungs.
Volume: 27
Issue: 9
Pages: 1403-14
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Publication
27768862 | J:238741
First Author: Ren S
Year: 2016
Journal: Am J Pathol
Title: Inactivation of Tsc2 in Mesoderm-Derived Cells Causes Polycystic Kidney Lesions and Impairs Lung Alveolarization.
Volume: 186
Issue: 12
Pages: 3261-3272
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Publication
37788104 | J:343526
 
First Author: Patel CH
Year: 2023
Journal: JCI Insight
Title: TSC2 S1365A mutation potently regulates CD8+ T cell function and differentiation and improves adoptive cellular cancer therapy.
Volume: 8
Issue: 21
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Publication
23123587 | J:197492
 
First Author: Reith RM
Year: 2013
Journal: Neurobiol Dis
Title: Loss of Tsc2 in Purkinje cells is associated with autistic-like behavior in a mouse model of tuberous sclerosis complex.
Volume: 51
Pages: 93-103
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Publication
31182472 | J:277323
 
First Author: Carlin D
Year: 2019
Journal: eNeuro
Title: Nociceptor Deletion of Tsc2 Enhances Axon Regeneration by Inducing a Conditioning Injury Response in Dorsal Root Ganglia.
Volume: 6
Issue: 3
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30508035 | J:277580
First Author: M A S
Year: 2019
Journal: Carcinogenesis
Title: Heterozygous Tsc2 (Tsc2+/-) mouse model to study induced renal cancer in response to ionizing radiation at low doses.
Volume: 40
Issue: 6
Pages: 782-790
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32912901 | J:303713
First Author: Van Nostrand JL
Year: 2020
Journal: Genes Dev
Title: AMPK regulation of Raptor and TSC2 mediate metformin effects on transcriptional control of anabolism and inflammation.
Volume: 34
Issue: 19-20
Pages: 1330-1344
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10096549 | J:52464
First Author: Kobayashi T
Year: 1999
Journal: Cancer Res
Title: Renal carcinogenesis, hepatic hemangiomatosis, and embryonic lethality caused by a germ-line Tsc2 mutation in mice.
Volume: 59
Issue: 6
Pages: 1206-11
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29766046 | J:266779
 
First Author: Carlin D
Year: 2018
Journal: eNeuro
Title: Deletion of Tsc2 in Nociceptors Reduces Target Innervation, Ion Channel Expression, and Sensitivity to Heat.
Volume: 5
Issue: 2
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12504590 | J:81245
First Author: Onda H
Year: 2002
Journal: Mol Cell Neurosci
Title: Tsc2 null murine neuroepithelial cells are a model for human tuber giant cells, and show activation of an mTOR pathway.
Volume: 21
Issue: 4
Pages: 561-74
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16027168 | J:100094
First Author: Ma L
Year: 2005
Journal: Genes Dev
Title: Genetic analysis of Pten and Tsc2 functional interactions in the mouse reveals asymmetrical haploinsufficiency in tumor suppression.
Volume: 19
Issue: 15
Pages: 1779-86
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25189766 | J:317521
First Author: Kaneko-Tarui T
Year: 2014
Journal: Mol Hum Reprod
Title: Hyperplasia and fibrosis in mice with conditional loss of the TSC2 tumor suppressor in Müllerian duct mesenchyme-derived myometria.
Volume: 20
Issue: 11
Pages: 1126-34
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26837766 | J:235545
First Author: D'Armiento J
Year: 2016
Journal: Cancer Res
Title: Mesenchymal Tumorigenesis Driven by TSC2 Haploinsufficiency Requires HMGA2 and Is Independent of mTOR Pathway Activation.
Volume: 76
Issue: 4
Pages: 844-54
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19150975 | J:146159
First Author: Way SW
Year: 2009
Journal: Hum Mol Genet
Title: Loss of Tsc2 in radial glia models the brain pathology of tuberous sclerosis complex in the mouse.
Volume: 18
Issue: 7
Pages: 1252-65
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18587048 | J:137850
First Author: Rachdi L
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Disruption of Tsc2 in pancreatic beta cells induces beta cell mass expansion and improved glucose tolerance in a TORC1-dependent manner.
Volume: 105
Issue: 27
Pages: 9250-5
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21062901 | J:167241
First Author: Zeng LH
Year: 2011
Journal: Hum Mol Genet
Title: Tsc2 gene inactivation causes a more severe epilepsy phenotype than Tsc1 inactivation in a mouse model of tuberous sclerosis complex.
Volume: 20
Issue: 3
Pages: 445-54
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20616807 | J:186339
First Author: Kang YJ
Year: 2011
Journal: Cell Death Differ
Title: The TSC1 and TSC2 tumor suppressors are required for proper ER stress response and protect cells from ER stress-induced apoptosis.
Volume: 18
Issue: 1
Pages: 133-44
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23732640 | J:214196
First Author: Jacobs BL
Year: 2013
Journal: J Physiol
Title: Eccentric contractions increase the phosphorylation of tuberous sclerosis complex-2 (TSC2) and alter the targeting of TSC2 and the mechanistic target of rapamycin to the lysosome.
Volume: 591
Issue: 18
Pages: 4611-20
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11438694 | J:70463
First Author: Kobayashi T
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: A germ-line Tsc1 mutation causes tumor development and embryonic lethality that are similar, but not identical to, those caused by Tsc2 mutation in mice.
Volume: 98
Issue: 15
Pages: 8762-7
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31461347 | J:290697
First Author: Gewin LS
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Inactivation of Tsc2 in Abcg2 lineage-derived cells drives the appearance of polycystic lesions and fibrosis in the adult kidney.
Volume: 317
Issue: 5
Pages: F1201-F1210
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7558029 | J:27400
First Author: Xu L
Year: 1995
Journal: Genomics
Title: Alternative splicing of the tuberous sclerosis 2 (TSC2) gene in human and mouse tissues.
Volume: 27
Issue: 3
Pages: 475-80
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22198573 | J:182345
First Author: Chévere-Torres I
Year: 2012
Journal: Neurobiol Dis
Title: Metabotropic glutamate receptor-dependent long-term depression is impaired due to elevated ERK signaling in the ΔRG mouse model of tuberous sclerosis complex.
Volume: 45
Issue: 3
Pages: 1101-10
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20038814 | J:156692
First Author: Ma J
Year: 2010
Journal: J Clin Invest
Title: Mammalian target of rapamycin regulates murine and human cell differentiation through STAT3/p63/Jagged/Notch cascade.
Volume: 120
Issue: 1
Pages: 103-14
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22752306 | J:187405
First Author: Yuan E
Year: 2012
Journal: Hum Mol Genet
Title: Graded loss of tuberin in an allelic series of brain models of TSC correlates with survival, and biochemical, histological and behavioral features.
Volume: 21
Issue: 19
Pages: 4286-300
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11030407 | J:64752
First Author: Cheadle JP
Year: 2000
Journal: Hum Genet
Title: Molecular genetic advances in tuberous sclerosis.
Volume: 107
Issue: 2
Pages: 97-114
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30910807 | J:286086
 
First Author: Rushing GV
Year: 2019
Journal: Life Sci Alliance
Title: Location-dependent maintenance of intrinsic susceptibility to mTORC1-driven tumorigenesis.
Volume: 2
Issue: 2
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9799836 | J:50577
First Author: Kawakami S
Year: 1998
Journal: Mamm Genome
Title: Tctex3, related to Drosophila polycomblike, is expressed in male germ cells and mapped to the mouse t-complex.
Volume: 9
Issue: 11
Pages: 874-80
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8777431 | J:33186
First Author: Kim KK
Year: 1995
Journal: Cell Mol Biol Res
Title: Cloning, developmental expression, and evidence for alternative splicing of the murine tuberous sclerosis (TSC2) gene product.
Volume: 41
Issue: 6
Pages: 515-26
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18316403 | J:135811
First Author: Shigeyama Y
Year: 2008
Journal: Mol Cell Biol
Title: Biphasic response of pancreatic beta-cell mass to ablation of tuberous sclerosis complex 2 in mice.
Volume: 28
Issue: 9
Pages: 2971-9
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20062052 | J:156683
First Author: Nie D
Year: 2010
Journal: Nat Neurosci
Title: Tsc2-Rheb signaling regulates EphA-mediated axon guidance.
Volume: 13
Issue: 2
Pages: 163-72
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34222844 | J:308160
First Author: Unachukwu U
Year: 2021
Journal: iScience
Title: Renal neoplasms in tuberous sclerosis mice are neurocristopathies.
Volume: 24
Issue: 7
Pages: 102684
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24529379 | J:338164
First Author: Menon S
Year: 2014
Journal: Cell
Title: Spatial control of the TSC complex integrates insulin and nutrient regulation of mTORC1 at the lysosome.
Volume: 156
Issue: 4
Pages: 771-85
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11703097 | J:73317
First Author: Lou D
Year: 2001
Journal: Mol Cell Biol Res Commun
Title: The tuberous sclerosis 2 gene product can localize to nuclei in a phosphorylation-dependent manner.
Volume: 4
Issue: 6
Pages: 374-80
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23955302 | J:201593
First Author: Zhang J
Year: 2013
Journal: Nat Cell Biol
Title: A tuberous sclerosis complex signalling node at the peroxisome regulates mTORC1 and autophagy in response to ROS.
Volume: 15
Issue: 10
Pages: 1186-96
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10491404 | J:57631
First Author: Onda H
Year: 1999
Journal: J Clin Invest
Title: Tsc2(+/-) mice develop tumors in multiple sites that express gelsolin and are influenced by genetic background.
Volume: 104
Issue: 6
Pages: 687-95
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23035046 | J:188257
First Author: Goncharova EA
Year: 2012
Journal: Sci Transl Med
Title: Prevention of alveolar destruction and airspace enlargement in a mouse model of pulmonary lymphangioleiomyomatosis (LAM).
Volume: 4
Issue: 154
Pages: 154ra134
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34806651 | J:316405
 
First Author: Thomas A
Year: 2021
Journal: JCI Insight
Title: Benign tumors in TSC are amenable to treatment by GD3 CAR T cells in mice.
Volume: 6
Issue: 22
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25700280 | J:222879
First Author: Hobbs RM
Year: 2015
Journal: EMBO Rep
Title: Distinct germline progenitor subsets defined through Tsc2-mTORC1 signaling.
Volume: 16
Issue: 4
Pages: 467-80
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22532572 | J:185369
First Author: Way SW
Year: 2012
Journal: Hum Mol Genet
Title: The differential effects of prenatal and/or postnatal rapamycin on neurodevelopmental defects and cognition in a neuroglial mouse model of tuberous sclerosis complex.
Volume: 21
Issue: 14
Pages: 3226-36
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Publication
21419848 | J:174327
First Author: Reith RM
Year: 2011
Journal: Neurobiol Dis
Title: Loss of the tuberous sclerosis complex protein tuberin causes Purkinje cell degeneration.
Volume: 43
Issue: 1
Pages: 113-22
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34576223 | J:313693
 
First Author: Czapski GA
Year: 2021
Journal: Int J Mol Sci
Title: Synaptic Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders.
Volume: 22
Issue: 18
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19527517 | J:157342
 
First Author: Pollizzi K
Year: 2009
Journal: Mol Cancer
Title: Equivalent benefit of mTORC1 blockade and combined PI3K-mTOR blockade in a mouse model of tuberous sclerosis.
Volume: 8
Pages: 38
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19602587 | J:150957
First Author: Huang J
Year: 2009
Journal: Cancer Res
Title: Signaling events downstream of mammalian target of rapamycin complex 2 are attenuated in cells and tumors deficient for the tuberous sclerosis complex tumor suppressors.
Volume: 69
Issue: 15
Pages: 6107-14
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23386687 | J:205463
First Author: Guo Y
Year: 2013
Journal: Mol Cancer Res
Title: Equivalent benefit of rapamycin and a potent mTOR ATP-competitive inhibitor, MLN0128 (INK128), in a mouse model of tuberous sclerosis.
Volume: 11
Issue: 5
Pages: 467-73
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22363765 | J:252088
First Author: Auricchio N
Year: 2012
Journal: PLoS One
Title: Therapeutic trial of metformin and bortezomib in a mouse model of tuberous sclerosis complex (TSC).
Volume: 7
Issue: 2
Pages: e31900
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30928642 | J:282236
 
First Author: Okamoto SI
Year: 2019
Journal: Neurobiol Dis
Title: NitroSynapsin for the treatment of neurological manifestations of tuberous sclerosis complex in a rodent model.
Volume: 127
Pages: 390-397
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37108467 | J:335265
 
First Author: Gąssowska-Dobrowolska M
Year: 2023
Journal: Int J Mol Sci
Title: Microtubule Cytoskeletal Network Alterations in a Transgenic Model of Tuberous Sclerosis Complex: Relevance to Autism Spectrum Disorders.
Volume: 24
Issue: 8
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15972957 | J:99509
First Author: Mak BC
Year: 2005
Journal: Am J Pathol
Title: Aberrant beta-catenin signaling in tuberous sclerosis.
Volume: 167
Issue: 1
Pages: 107-16
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20534473 | J:161396
First Author: Young DM
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Altered ultrasonic vocalizations in a tuberous sclerosis mouse model of autism.
Volume: 107
Issue: 24
Pages: 11074-9
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16390268 | J:107438
First Author: Brown AB
Year: 2005
Journal: Hum Gene Ther
Title: Magnetic resonance imaging and characterization of spontaneous lesions in a transgenic mouse model of tuberous sclerosis as a model for endothelial cell-based transgene delivery.
Volume: 16
Issue: 12
Pages: 1367-76
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20159776 | J:159339
First Author: Cao J
Year: 2010
Journal: Hum Mol Genet
Title: Thoracic aortic disease in tuberous sclerosis complex: molecular pathogenesis and potential therapies in Tsc2+/- mice.
Volume: 19
Issue: 10
Pages: 1908-20
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32303566 | J:288768
 
First Author: Saré RM
Year: 2020
Journal: eNeuro
Title: Sex-Selective Effects on Behavior in a Mouse Model of Tuberous Sclerosis Complex.
Volume: 7
Issue: 2
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29635516 | J:262779
First Author: McKenna J 3rd
Year: 2018
Journal: Hum Mol Genet
Title: Metabolomic studies identify changes in transmethylation and polyamine metabolism in a brain-specific mouse model of tuberous sclerosis complex.
Volume: 27
Issue: 12
Pages: 2113-2124
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23081885 | J:217855
First Author: Tsai V
Year: 2014
Journal: Cereb Cortex
Title: Fetal brain mTOR signaling activation in tuberous sclerosis complex.
Volume: 24
Issue: 2
Pages: 315-27
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29491408 | J:263157
First Author: Shi Q
Year: 2018
Journal: Sci Rep
Title: Nox4 is a Target for Tuberin Deficiency Syndrome.
Volume: 8
Issue: 1
Pages: 3781
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32579942 | J:304326
First Author: Di Nardo A
Year: 2020
Journal: Cell Rep
Title: Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia.
Volume: 31
Issue: 12
Pages: 107780
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16027169 | J:100095
First Author: Manning BD
Year: 2005
Journal: Genes Dev
Title: Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2.
Volume: 19
Issue: 15
Pages: 1773-8
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12438748 | J:79792
First Author: Simckes AM
Year: 2002
Journal: Cytogenet Genome Res
Title: Chromosomal localization of three vacuolar-H+ -ATPase 16 kDa subunit (ATP6V0C) genes in the murine genome.
Volume: 97
Issue: 1-2
Pages: 111-5
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24740570 | J:229869
First Author: Bartolomé A
Year: 2014
Journal: Diabetes
Title: Pancreatic β-cell failure mediated by mTORC1 hyperactivity and autophagic impairment.
Volume: 63
Issue: 9
Pages: 2996-3008
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29080681 | J:259390
First Author: Yang F
Year: 2018
Journal: J Invest Dermatol
Title: Uncoupling of ER/Mitochondrial Oxidative Stress in mTORC1 Hyperactivation-Associated Skin Hypopigmentation.
Volume: 138
Issue: 3
Pages: 669-678
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Publication
31978189 | J:284067
First Author: Yang F
Year: 2020
Journal: PLoS One
Title: Epilepsy in a melanocyte-lineage mTOR hyperactivation mouse model: A novel epilepsy model.
Volume: 15
Issue: 1
Pages: e0228204
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Publication
27760312 | J:240756
First Author: Ebrahimi-Fakhari D
Year: 2016
Journal: Cell Rep
Title: Impaired Mitochondrial Dynamics and Mitophagy in Neuronal Models of Tuberous Sclerosis Complex.
Volume: 17
Issue: 4
Pages: 1053-1070
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Publication
12820960 | J:338163
First Author: Garami A
Year: 2003
Journal: Mol Cell
Title: Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2.
Volume: 11
Issue: 6
Pages: 1457-66
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Publication
25155956 | J:217829
First Author: Tang G
Year: 2014
Journal: Neuron
Title: Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits.
Volume: 83
Issue: 5
Pages: 1131-43
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Publication
37293130 | J:346335
 
First Author: Chalkiadaki K
Year: 2023
Journal: Front Cell Dev Biol
Title: Reversal of memory and autism-related phenotypes in Tsc2(+/-) mice via inhibition of Nlgn1.
Volume: 11
Pages: 1205112
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Publication
11875047 | J:75243
First Author: Kwiatkowski DJ
Year: 2002
Journal: Hum Mol Genet
Title: A mouse model of TSC1 reveals sex-dependent lethality from liver hemangiomas, and up-regulation of p70S6 kinase activity in Tsc1 null cells.
Volume: 11
Issue: 5
Pages: 525-34
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Publication
28092373 | J:260616
First Author: Linke M
Year: 2017
Journal: Nat Immunol
Title: Chronic signaling via the metabolic checkpoint kinase mTORC1 induces macrophage granuloma formation and marks sarcoidosis progression.
Volume: 18
Issue: 3
Pages: 293-302
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Publication
24874429 | J:232230
First Author: Sun Y
Year: 2014
Journal: Am J Respir Cell Mol Biol
Title: Rapamycin-resistant poly (ADP-ribose) polymerase-1 overexpression is a potential therapeutic target in lymphangioleiomyomatosis.
Volume: 51
Issue: 6
Pages: 738-49
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Publication
22795129 | J:187614
First Author: Dibble CC
Year: 2012
Journal: Mol Cell
Title: TBC1D7 is a third subunit of the TSC1-TSC2 complex upstream of mTORC1.
Volume: 47
Issue: 4
Pages: 535-46
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Publication
21387562 | J:234610
First Author: Bernardi R
Year: 2011
Journal: EMBO Mol Med
Title: Pml represses tumour progression through inhibition of mTOR.
Volume: 3
Issue: 5
Pages: 249-57
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Publication
8661056 | J:33374
First Author: Olsson PG
Year: 1996
Journal: Genomics
Title: The mouse homologue of the polycystic kidney disease gene (Pkd1) is a single-copy gene.
Volume: 34
Issue: 2
Pages: 233-5
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Publication
32588887 | J:294610
First Author: Kapfhamer D
Year: 2020
Journal: Hum Mol Genet
Title: Ornithine decarboxylase, the rate-limiting enzyme of polyamine synthesis, modifies brain pathology in a mouse model of tuberous sclerosis complex.
Volume: 29
Issue: 14
Pages: 2395-2407
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Publication
20146790 | J:283264
 
First Author: Woodrum C
Year: 2010
Journal: J Transl Med
Title: Comparison of three rapamycin dosing schedules in A/J Tsc2+/- mice and improved survival with angiogenesis inhibitor or asparaginase treatment in mice with subcutaneous tuberous sclerosis related tumors.
Volume: 8
Pages: 14
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Publication
25880340 | J:222712
 
First Author: Sugiura H
Year: 2015
Journal: Nat Commun
Title: Rheb activation disrupts spine synapse formation through accumulation of syntenin in tuberous sclerosis complex.
Volume: 6
Pages: 6842
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Publication
24077282 | J:214354
First Author: Wang F
Year: 2014
Journal: Oncogene
Title: Pivotal role of augmented αB-crystallin in tumor development induced by deficient TSC1/2 complex.
Volume: 33
Issue: 34
Pages: 4352-8
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