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Search results 201 to 233 out of 233 for Smyd2

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Type Details Score
Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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UniProt Feature
UniProt Feature
Begin: 853
Description: N6-methyllysine; by SMYD2
Type: modified residue
End: 853
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UniProt Feature
UniProt Feature
Begin: 803
Description: N6-methyllysine; by SMYD2
Type: modified residue
End: 803
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UniProt Feature
UniProt Feature
Begin: 1
Description: N-lysine methyltransferase SMYD2
Type: chain
End: 433
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Publication
33127671 | J:313066
 
First Author: Li LX
Year: 2020
Journal: Sci Adv
Title: Cross-talk between CDK4/6 and SMYD2 regulates gene transcription, tubulin methylation, and ciliogenesis.
Volume: 6
Issue: 44
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Publication
18065756 | -
First Author: Abu-Farha M
Year: 2008
Journal: Mol Cell Proteomics
Title: The tale of two domains: proteomics and genomics analysis of SMYD2, a new histone methyltransferase.
Volume: 7
Issue: 3
Pages: 560-72
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Interaction Experiment
Diehl F (2010)
Description: Cardiac deletion of Smyd2 is dispensable for mouse heart development.
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Allele
Smyd2<em1Smoc> | MGI:7292491
Name: SET and MYND domain containing 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
32408548 | -
 
First Author: Jarrell DK
Year: 2020
Journal: Vet Sci
Title: Characterizing the Role of SMYD2 in Mammalian Embryogenesis-Future Directions.
Volume: 7
Issue: 2
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Publication
26826421 | -
 
First Author: Ohtomo-Oda R
Year: 2016
Journal: Hum Pathol
Title: SMYD2 overexpression is associated with tumor cell proliferation and a worse outcome in human papillomavirus-unrelated nonmultiple head and neck carcinomas.
Volume: 49
Pages: 145-55
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Publication
20870719 | -
First Author: Saddic LA
Year: 2010
Journal: J Biol Chem
Title: Methylation of the retinoblastoma tumor suppressor by SMYD2.
Volume: 285
Issue: 48
Pages: 37733-40
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Protein Domain
IPR044419 | SMYD2_SET
Type: Domain
Description: This entry represents the SET domain of SET and MYND domain-containing protein 2 (SMYD2). SMYD2 functions as a histone methyltransferase that methylates both histones and non-histone proteins, including p53/TP53 and RB1 [, ]. It specifically methylates histone H3 'Lys-4' (H3K4me) and dimethylates histone H3 'Lys-36' (H3K36me2). It plays a role in myofilament organisation in both skeletal and cardiac muscles via Hsp90 methylation []. SMYD2 overexpression is associated with tumour cell proliferation and a worse outcome in human papillomavirus-unrelated nonmultiple head and neck carcinomas []. It regulates leukemia cell growth such that diminished SMYD2 expression upregulates SET7/9, thereby possibly shifting leukemia cells from growth to quiescence state associated with resistance to DNA damage associated with Acute Myeloid Leukemia (AML) [].The SMYD family consists of five members including SMYD1/2/3/4/5. They contain two highly conserved structural and functional domains, the SET and MYND domains. The SET domain is involved in lysine methylation, while the MYND domain is involved in protein-protein interaction. They are essential in several mammalian developmental pathways [, , , ].
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Publication
37040760 | J:337236
First Author: Wang Z
Year: 2023
Journal: Cell
Title: Positive selection of somatically mutated clones identifies adaptive pathways in metabolic liver disease.
Volume: 186
Issue: 9
Pages: 1968-1984.e20
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Publication
29718165 | J:261401
First Author: Li Q
Year: 2018
Journal: Endocrinology
Title: Bisphenol A and Phthalates Modulate Peritoneal Macrophage Function in Female Mice Involving SYMD2-H3K36 Dimethylation.
Volume: 159
Issue: 5
Pages: 2216-2228
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Publication
25125178 | -
First Author: Du SJ
Year: 2014
Journal: Anat Rec (Hoboken)
Title: SMYD proteins: key regulators in skeletal and cardiac muscle development and function.
Volume: 297
Issue: 9
Pages: 1650-62
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Publication
26985287 | -
First Author: Mitchell LH
Year: 2016
Journal: ACS Med Chem Lett
Title: Novel Oxindole Sulfonamides and Sulfamides: EPZ031686, the First Orally Bioavailable Small Molecule SMYD3 Inhibitor.
Volume: 7
Issue: 2
Pages: 134-8
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Publication
26101576 | -
First Author: Sweis RF
Year: 2015
Journal: ACS Med Chem Lett
Title: Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2.
Volume: 6
Issue: 6
Pages: 695-700
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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