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Search results 101 to 200 out of 221 for Mcm3

0.035s
Type Details Score
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_17
Specimen Label: euxassay_001694_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_18
Specimen Label: euxassay_001694_18
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_19
Specimen Label: euxassay_001694_19
Detected: true
Specimen Num: 18
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_20
Specimen Label: euxassay_001694_20
Detected: true
Specimen Num: 19
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1691323
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_21
Specimen Label: euxassay_001694_21
Detected: true
Specimen Num: 20
GXD Expression  
Probe: MGI:4844319
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1636717
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:4848309
Age: embryonic day 10.5
Note: Staining is present in the external genitalia.
Specimen Label: Table S4 - E10.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_05
Specimen Label: euxassay_001694_05
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_06
Specimen Label: euxassay_001694_06
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_07
Specimen Label: euxassay_001694_07
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_08
Specimen Label: euxassay_001694_08
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_09
Specimen Label: euxassay_001694_09
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_10
Specimen Label: euxassay_001694_10
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_11
Specimen Label: euxassay_001694_11
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_12
Specimen Label: euxassay_001694_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_13
Specimen Label: euxassay_001694_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1697923
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_14
Specimen Label: euxassay_001694_14
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_02
Specimen Label: euxassay_001694_02
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_03
Specimen Label: euxassay_001694_03
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_04
Specimen Label: euxassay_001694_04
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_16
Specimen Label: euxassay_001694_16
Detected: true
Specimen Num: 15
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_17
Specimen Label: euxassay_001694_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856523
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_18
Specimen Label: euxassay_001694_18
Detected: true
Specimen Num: 17
GXD Expression  
Probe: MGI:4844319
Assay Type: RNA in situ
Annotation Date: 2010-12-22
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1616419
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4848309
Age: embryonic day 11.5
Note: Staining is present in the lateral neural tube.
Specimen Label: Table S4 - E11.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2023-08-31
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7522816
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_12
Specimen Label: euxassay_001694_12
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_13
Specimen Label: euxassay_001694_13
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_17
Specimen Label: euxassay_001694_17
Detected: true
Specimen Num: 16
GXD Expression  
Probe: MGI:951809
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778223
Pattern: Uniform
Stage: TS23
Assay Id: MGI:4826128
Age: embryonic day 14.5
Image: euxassay_001694_18
Specimen Label: euxassay_001694_18
Detected: true
Specimen Num: 17
Publication
First Author: Hughes CR
Year: 2012
Journal: J Clin Invest
Title: MCM4 mutation causes adrenal failure, short stature, and natural killer cell deficiency in humans.
Volume: 122
Issue: 3
Pages: 814-20
Publication
First Author: Kimura H
Year: 1995
Journal: Nucleic Acids Res
Title: Molecular cloning of cDNA encoding mouse Cdc21 and CDC46 homologs and characterization of the products: physical interaction between P1(MCM3) and CDC46 proteins.
Volume: 23
Issue: 12
Pages: 2097-104
Publication
First Author: Schaefer S
Year: 2019
Journal: Sci Rep
Title: Down-regulation of CK2α correlates with decreased expression levels of DNA replication minichromosome maintenance protein complex (MCM) genes.
Volume: 9
Issue: 1
Pages: 14581
Publication
First Author: Yoshida I
Year: 1996
Journal: Genomics
Title: The mouse Mcmd gene for DNA replication protein P1MCM3 maps to bands A3-A5 on chromosome 1 by fluorescence in situ hybridization.
Volume: 32
Issue: 3
Pages: 483-4
Publication
First Author: O'Driscoll M
Year: 2017
Journal: J Pathol
Title: The pathological consequences of impaired genome integrity in humans; disorders of the DNA replication machinery.
Volume: 241
Issue: 2
Pages: 192-207
Publication
First Author: Cecchini MJ
Year: 2014
Journal: Mol Cell Biol
Title: A retinoblastoma allele that is mutated at its common E2F interaction site inhibits cell proliferation in gene-targeted mice.
Volume: 34
Issue: 11
Pages: 2029-45
Publication
First Author: McNairn AJ
Year: 2019
Journal: Nature
Title: Female-biased embryonic death from inflammation induced by genomic instability.
Volume: 567
Issue: 7746
Pages: 105-108
Publication  
First Author: Alvarez S
Year: 2015
Journal: Nat Commun
Title: Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality.
Volume: 6
Pages: 8548
Publication
First Author: Okano-Uchida T
Year: 2018
Journal: Genes Dev
Title: Endoreduplication of the mouse genome in the absence of ORC1.
Volume: 32
Issue: 13-14
Pages: 978-990
Publication
First Author: Leturcq M
Year: 2018
Journal: Cell Mol Life Sci
Title: O-GlcNAc transferase associates with the MCM2-7 complex and its silencing destabilizes MCM-MCM interactions.
Volume: 75
Issue: 23
Pages: 4321-4339
Publication
First Author: Kuipers MA
Year: 2011
Journal: J Cell Biol
Title: Highly stable loading of Mcm proteins onto chromatin in living cells requires replication to unload.
Volume: 192
Issue: 1
Pages: 29-41
Publication
First Author: Kang YH
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase epsilon in rolling circle DNA synthesis.
Volume: 109
Issue: 16
Pages: 6042-7
Publication
First Author: Lee EY
Year: 2009
Journal: Dev Biol
Title: E2F4 cooperates with pRB in the development of extra-embryonic tissues.
Volume: 332
Issue: 1
Pages: 104-15
Publication
First Author: Wenzel PL
Year: 2011
Journal: Dev Biol
Title: Cell proliferation in the absence of E2F1-3.
Volume: 351
Issue: 1
Pages: 35-45
Publication
First Author: Wang Y
Year: 2004
Journal: Cancer Res
Title: A chemically induced model for squamous cell carcinoma of the lung in mice: histopathology and strain susceptibility.
Volume: 64
Issue: 5
Pages: 1647-54
Publication
First Author: Hwang SY
Year: 2001
Journal: Mol Reprod Dev
Title: Expression of genes involved in mammalian meiosis during the transition from egg to embryo.
Volume: 59
Issue: 2
Pages: 144-58
Publication
First Author: Ajioka I
Year: 2006
Journal: Eur J Neurosci
Title: Identification of ventricular-side-enriched molecules regulated in a stage-dependent manner during cerebral cortical development.
Volume: 23
Issue: 2
Pages: 296-308
Publication
First Author: Tane S
Year: 2014
Journal: J Biol Chem
Title: Repression of cyclin D1 expression is necessary for the maintenance of cell cycle exit in adult mammalian cardiomyocytes.
Volume: 289
Issue: 26
Pages: 18033-44
Publication
First Author: Cho A
Year: 2008
Journal: Dev Biol
Title: FKBP8 cell-autonomously controls neural tube patterning through a Gli2- and Kif3a-dependent mechanism.
Volume: 321
Issue: 1
Pages: 27-39
Publication
First Author: Millien G
Year: 2008
Journal: Gene Expr Patterns
Title: Characterization of the mid-foregut transcriptome identifies genes regulated during lung bud induction.
Volume: 8
Issue: 2
Pages: 124-39
Publication
First Author: Lumayag S
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Inactivation of the microRNA-183/96/182 cluster results in syndromic retinal degeneration.
Volume: 110
Issue: 6
Pages: E507-16
Publication
First Author: Neidhardt L
Year: 2000
Journal: Mech Dev
Title: Large-scale screen for genes controlling mammalian embryogenesis, using high-throughput gene expression analysis in mouse embryos.
Volume: 98
Issue: 1-2
Pages: 77-94
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication
First Author: Koss M
Year: 2012
Journal: Dev Cell
Title: Congenital asplenia in mice and humans with mutations in a Pbx/Nkx2-5/p15 module.
Volume: 22
Issue: 5
Pages: 913-26
Publication
First Author: Sansom SN
Year: 2009
Journal: PLoS Genet
Title: The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis.
Volume: 5
Issue: 6
Pages: e1000511
Publication      
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication        
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
Publication
First Author: Ko MS
Year: 2000
Journal: Development
Title: Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development.
Volume: 127
Issue: 8
Pages: 1737-49
Publication
First Author: Yokoyama S
Year: 2009
Journal: Dev Cell
Title: A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58.
Volume: 17
Issue: 6
Pages: 836-48
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication  
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
Publication
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: frog, western clawed
UniProt Feature
Begin: 2
Description: DNA replication licensing factor MCM3
Type: chain
End: 812
Interaction Experiment
Description: Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies.
Publication
First Author: Shi Y
Year: 2007
Journal: J Biol Chem
Title: Identification of carboxyl-terminal MCM3 phosphorylation sites using polyreactive phosphospecific antibodies.
Volume: 282
Issue: 12
Pages: 9236-43
Publication
First Author: Kuwahara K
Year: 2000
Journal: Blood
Title: A novel nuclear phosphoprotein, GANP, is up-regulated in centrocytes of the germinal center and associated with MCM3, a protein essential for DNA replication.
Volume: 95
Issue: 7
Pages: 2321-8
Gene
Type: gene
Organism: frog, African clawed
Publication
First Author: Lin DI
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Phosphorylation of MCM3 on Ser-112 regulates its incorporation into the MCM2-7 complex.
Volume: 105
Issue: 23
Pages: 8079-84
Publication
First Author: Sherman DA
Year: 1998
Journal: Nucleic Acids Res
Title: Schizosaccharomyces pombe Mcm3p, an essential nuclear protein, associates tightly with Nda4p (Mcm5p).
Volume: 26
Issue: 17
Pages: 3955-60
Publication
First Author: Albani F
Year: 1998
Journal: J Exp Zool
Title: B24 protein stored in lampbrush spheres is involved in early cleavage in urodele amphibians.
Volume: 280
Issue: 2
Pages: 142-51
Publication  
First Author: Singh SK
Year: 2013
Journal: Nat Commun
Title: GANP regulates recruitment of AID to immunoglobulin variable regions by modulating transcription and nucleosome occupancy.
Volume: 4
Pages: 1830
Publication
First Author: Eid MM
Year: 2014
Journal: J Immunol
Title: GANP regulates the choice of DNA repair pathway by DNA-PKcs interaction in AID-dependent IgV region diversification.
Volume: 192
Issue: 12
Pages: 5529-39
Publication
First Author: Takei Y
Year: 2001
Journal: EMBO Rep
Title: MCM3AP, a novel acetyltransferase that acetylates replication protein MCM3.
Volume: 2
Issue: 2
Pages: 119-23
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif (RRM) of MCM3-associated protein (MCM3AP, also known as GANP), a nuclear protein with multiple domains, which have different functions. GANP serves as the scaffold of the mammalian TREX-2 complex that links transcription with nuclear messenger RNA export []. GANP can act as an RNA export factor that interacts with activation-induced cytidine deaminase (AID) and shepherds it from the cytoplasm to the nucleus, and toward the IgV region loci in B cells []. GANP contains the Sac3-homology domain, a putative RNA recognition motif, the Nup-homology domain, and the C-terminal histone-acetyltransferase (HAT) domain. Its HAT domain has been shown to regulate minichromosome maintenance protein 3 (MCM3) []. An alternatively spliced variant of GANP mRNA has been reported in humans. A shorter isoform of GANP (likely to encode an 80kDa protein) is associated with MCM3 of the DNA helicase MCM-complex (composed of MCM2-MCM7) and possesses HAT activity [].