Type |
Details |
Score |
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
687
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
965
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
580
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
550
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
580
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
590
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
558
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Yun J |
Year: |
2014 |
Journal: |
Elife |
Title: |
MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin. |
Volume: |
3 |
|
Pages: |
e01958 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liang H |
Year: |
2014 |
Journal: |
Cell Metab |
Title: |
PTENα, a PTEN isoform translated through alternative initiation, regulates mitochondrial function and energy metabolism. |
Volume: |
19 |
Issue: |
5 |
Pages: |
836-48 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sarraf SA |
Year: |
2019 |
Journal: |
Cell Rep |
Title: |
PINK1/Parkin Influences Cell Cycle by Sequestering TBK1 at Damaged Mitochondria, Inhibiting Mitosis. |
Volume: |
29 |
Issue: |
1 |
Pages: |
225-235.e5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Baranov SV |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Mitochondria modulate programmed neuritic retraction. |
Volume: |
116 |
Issue: |
2 |
Pages: |
650-659 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dhungel N |
Year: |
2015 |
Journal: |
Neuron |
Title: |
Parkinson's disease genes VPS35 and EIF4G1 interact genetically and converge on α-synuclein. |
Volume: |
85 |
Issue: |
1 |
Pages: |
76-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carneiro FRG |
Year: |
2018 |
Journal: |
Cell Rep |
Title: |
An Essential Role for ECSIT in Mitochondrial Complex I Assembly and Mitophagy in Macrophages. |
Volume: |
22 |
Issue: |
10 |
Pages: |
2654-2666 |
|
•
•
•
•
•
|
Publication |
First Author: |
Murakami K |
Year: |
2021 |
Journal: |
Cell Rep |
Title: |
OGT Regulates Hematopoietic Stem Cell Maintenance via PINK1-Dependent Mitophagy. |
Volume: |
34 |
Issue: |
1 |
Pages: |
108579 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gong G |
Year: |
2015 |
Journal: |
Science |
Title: |
Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice. |
Volume: |
350 |
Issue: |
6265 |
Pages: |
aad2459 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhu Q |
Year: |
2023 |
Journal: |
Nat Commun |
Title: |
GRAF1 integrates PINK1-Parkin signaling and actin dynamics to mediate cardiac mitochondrial homeostasis. |
Volume: |
14 |
Issue: |
1 |
Pages: |
8187 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fang EF |
Year: |
2014 |
Journal: |
Cell |
Title: |
Defective mitophagy in XPA via PARP-1 hyperactivation and NAD(+)/SIRT1 reduction. |
Volume: |
157 |
Issue: |
4 |
Pages: |
882-896 |
|
•
•
•
•
•
|
Publication |
First Author: |
Okatsu K |
Year: |
2010 |
Journal: |
Genes Cells |
Title: |
p62/SQSTM1 cooperates with Parkin for perinuclear clustering of depolarized mitochondria. |
Volume: |
15 |
Issue: |
8 |
Pages: |
887-900 |
|
•
•
•
•
•
|
Publication |
First Author: |
Torii S |
Year: |
2020 |
Journal: |
Int J Mol Sci |
Title: |
Mitochondrial E3 Ubiquitin Ligase Parkin: Relationships with Other Causal Proteins in Familial Parkinson's Disease and Its Substrate-Involved Mouse Experimental Models. |
Volume: |
21 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ochi S |
Year: |
2020 |
Journal: |
Mol Neurobiol |
Title: |
Identifying Blood Transcriptome Biomarkers of Alzheimer's Disease Using Transgenic Mice. |
Volume: |
57 |
Issue: |
12 |
Pages: |
4941-4951 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roe ND |
Year: |
2015 |
Journal: |
Biochim Biophys Acta |
Title: |
Targeted deletion of PTEN in cardiomyocytes renders cardiac contractile dysfunction through interruption of Pink1-AMPK signaling and autophagy. |
Volume: |
1852 |
Issue: |
2 |
Pages: |
290-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu T |
Year: |
2023 |
Journal: |
Cells |
Title: |
Disruption of Mitophagy Flux through the PARL-PINK1 Pathway by CHCHD10 Mutations or CHCHD10 Depletion. |
Volume: |
12 |
Issue: |
24 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
McWilliams TG |
Year: |
2018 |
Journal: |
Open Biol |
Title: |
Phosphorylation of Parkin at serine 65 is essential for its activation in vivo. |
Volume: |
8 |
Issue: |
11 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mucha O |
Year: |
2021 |
Journal: |
Int J Mol Sci |
Title: |
Dysregulated Autophagy and Mitophagy in a Mouse Model of Duchenne Muscular Dystrophy Remain Unchanged Following Heme Oxygenase-1 Knockout. |
Volume: |
23 |
Issue: |
1 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Irrcher I |
Year: |
2010 |
Journal: |
Hum Mol Genet |
Title: |
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics. |
Volume: |
19 |
Issue: |
19 |
Pages: |
3734-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lu W |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
e0147792 |
|
•
•
•
•
•
|
Publication |
First Author: |
Khang R |
Year: |
2015 |
Journal: |
Neuroscience |
Title: |
Dysregulation of parkin in the substantia nigra of db/db and high-fat diet mice. |
Volume: |
294 |
|
Pages: |
182-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Malik AU |
Year: |
2021 |
Journal: |
Biochem J |
Title: |
Deciphering the LRRK code: LRRK1 and LRRK2 phosphorylate distinct Rab proteins and are regulated by diverse mechanisms. |
Volume: |
478 |
Issue: |
3 |
Pages: |
553-578 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou G |
Year: |
2023 |
Journal: |
Int Immunopharmacol |
Title: |
Mitochondrial calcium uptake 3 mitigates cerebral amyloid angiopathy-related neuronal death and glial inflammation by reducing mitochondrial dysfunction. |
Volume: |
117 |
|
Pages: |
109614 |
|
•
•
•
•
•
|
Publication |
First Author: |
Narala VR |
Year: |
2018 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
Akap1 genetic deletion increases the severity of hyperoxia-induced acute lung injury in mice. |
Volume: |
314 |
Issue: |
5 |
Pages: |
L860-L870 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo H |
Year: |
2021 |
Journal: |
Acta Physiol (Oxf) |
Title: |
Pharmacological inhibition of USP30 activates tissue-specific mitophagy. |
Volume: |
232 |
Issue: |
3 |
Pages: |
e13666 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rossin F |
Year: |
2015 |
Journal: |
Cell Death Differ |
Title: |
Transglutaminase 2 ablation leads to mitophagy impairment associated with a metabolic shift towards aerobic glycolysis. |
Volume: |
22 |
Issue: |
3 |
Pages: |
408-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roy A |
Year: |
2016 |
Journal: |
Sci Rep |
Title: |
BPOZ-2 Gene Delivery Ameliorates Alpha-Synucleinopathy in A53T Transgenic Mouse Model of Parkinson's Disease. |
Volume: |
6 |
|
Pages: |
22067 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hull TD |
Year: |
2016 |
Journal: |
JCI Insight |
Title: |
Heme oxygenase-1 regulates mitochondrial quality control in the heart. |
Volume: |
1 |
Issue: |
2 |
Pages: |
e85817 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shires SE |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Nuclear Parkin Activates the ERRα Transcriptional Program and Drives Widespread Changes in Gene Expression Following Hypoxia. |
Volume: |
10 |
Issue: |
1 |
Pages: |
8499 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peker N |
Year: |
2018 |
Journal: |
Am J Physiol Cell Physiol |
Title: |
Loss of Parkin impairs mitochondrial function and leads to muscle atrophy. |
Volume: |
315 |
Issue: |
2 |
Pages: |
C164-C185 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dongil P |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
Pas Kinase Deficiency Triggers Antioxidant Mechanisms in the Liver. |
Volume: |
8 |
Issue: |
1 |
Pages: |
13810 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dusonchet J |
Year: |
2014 |
Journal: |
Hum Mol Genet |
Title: |
A Parkinson's disease gene regulatory network identifies the signaling protein RGS2 as a modulator of LRRK2 activity and neuronal toxicity. |
Volume: |
23 |
Issue: |
18 |
Pages: |
4887-905 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi G |
Year: |
2011 |
Journal: |
Hum Mol Genet |
Title: |
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease. |
Volume: |
20 |
Issue: |
10 |
Pages: |
1966-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quadri M |
Year: |
2013 |
Journal: |
Hum Mutat |
Title: |
Mutation in the SYNJ1 gene associated with autosomal recessive, early-onset Parkinsonism. |
Volume: |
34 |
Issue: |
9 |
Pages: |
1208-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Coughlin L |
Year: |
2015 |
Journal: |
Invest Ophthalmol Vis Sci |
Title: |
Mitochondrial morphology differences and mitophagy deficit in murine glaucomatous optic nerve. |
Volume: |
56 |
Issue: |
3 |
Pages: |
1437-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bernardini JP |
Year: |
2017 |
Journal: |
Oncogene |
Title: |
Parkin and mitophagy in cancer. |
Volume: |
36 |
Issue: |
10 |
Pages: |
1315-1327 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aguirre JD |
Year: |
2017 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Structure of phosphorylated UBL domain and insights into PINK1-orchestrated parkin activation. |
Volume: |
114 |
Issue: |
2 |
Pages: |
298-303 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang C |
Year: |
2017 |
Journal: |
J Biol Chem |
Title: |
Sorafenib targets the mitochondrial electron transport chain complexes and ATP synthase to activate the PINK1-Parkin pathway and modulate cellular drug response. |
Volume: |
292 |
Issue: |
36 |
Pages: |
15105-15120 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moller A |
Year: |
2017 |
Journal: |
Hum Mol Genet |
Title: |
Amyotrophic lateral sclerosis-associated mutant SOD1 inhibits anterograde axonal transport of mitochondria by reducing Miro1 levels. |
Volume: |
26 |
Issue: |
23 |
Pages: |
4668-4679 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhang X |
Year: |
2017 |
Journal: |
FASEB J |
Title: |
Calcium/calmodulin-dependent protein kinase regulates the PINK1/Parkin and DJ-1 pathways of mitophagy during sepsis. |
Volume: |
31 |
Issue: |
10 |
Pages: |
4382-4395 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bertolin G |
Year: |
2015 |
Journal: |
Cell Death Differ |
Title: |
Parkin maintains mitochondrial levels of the protective Parkinson's disease-related enzyme 17-β hydroxysteroid dehydrogenase type 10. |
Volume: |
22 |
Issue: |
10 |
Pages: |
1563-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Verma M |
Year: |
2020 |
Journal: |
J Biol Chem |
Title: |
Chronic treatment with the complex I inhibitor MPP+ depletes endogenous PTEN-induced kinase 1 (PINK1) via up-regulation of Bcl-2-associated athanogene 6 (BAG6). |
Volume: |
295 |
Issue: |
23 |
Pages: |
7865-7876 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Z |
Year: |
2022 |
Journal: |
Redox Biol |
Title: |
XBP1 deficiency promotes hepatocyte pyroptosis by impairing mitophagy to activate mtDNA-cGAS-STING signaling in macrophages during acute liver injury. |
Volume: |
52 |
|
Pages: |
102305 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu WN |
Year: |
2023 |
Journal: |
Int J Biol Sci |
Title: |
Sesn2 Serves as a Regulator between Mitochondrial Unfolded Protein Response and Mitophagy in Intervertebral Disc Degeneration. |
Volume: |
19 |
Issue: |
2 |
Pages: |
571-592 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zhou X |
Year: |
2023 |
Journal: |
Front Pharmacol |
Title: |
Evaluation of therapeutic effects of tetramethylpyrazine nitrone in Alzheimer's disease mouse model and proteomics analysis. |
Volume: |
14 |
|
Pages: |
1082602 |
|
•
•
•
•
•
|
Publication |
First Author: |
Roca-Agujetas V |
Year: |
2021 |
Journal: |
Mol Neurodegener |
Title: |
Cholesterol alters mitophagy by impairing optineurin recruitment and lysosomal clearance in Alzheimer's disease. |
Volume: |
16 |
Issue: |
1 |
Pages: |
15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Simonovitch S |
Year: |
2019 |
Journal: |
J Alzheimers Dis |
Title: |
The Effects of APOE4 on Mitochondrial Dynamics and Proteins in vivo. |
Volume: |
70 |
Issue: |
3 |
Pages: |
861-875 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yazdani HO |
Year: |
2019 |
Journal: |
Cancer Res |
Title: |
Neutrophil Extracellular Traps Drive Mitochondrial Homeostasis in Tumors to Augment Growth. |
Volume: |
79 |
Issue: |
21 |
Pages: |
5626-5639 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chi HC |
Year: |
2017 |
Journal: |
Oncogene |
Title: |
Thyroid hormone protects hepatocytes from HBx-induced carcinogenesis by enhancing mitochondrial turnover. |
Volume: |
36 |
Issue: |
37 |
Pages: |
5274-5284 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lai YC |
Year: |
2015 |
Journal: |
EMBO J |
Title: |
Phosphoproteomic screening identifies Rab GTPases as novel downstream targets of PINK1. |
Volume: |
34 |
Issue: |
22 |
Pages: |
2840-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Livingston MJ |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
Clearance of damaged mitochondria via mitophagy is important to the protective effect of ischemic preconditioning in kidneys. |
Volume: |
15 |
Issue: |
12 |
Pages: |
2142-2162 |
|
•
•
•
•
•
|
Publication |
First Author: |
Araya J |
Year: |
2019 |
Journal: |
Autophagy |
Title: |
PRKN-regulated mitophagy and cellular senescence during COPD pathogenesis. |
Volume: |
15 |
Issue: |
3 |
Pages: |
510-526 |
|
•
•
•
•
•
|