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Search results 201 to 300 out of 608 for Nphs2

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Type Details Score
Publication
18046313 | J:147670
First Author: Doné SC
Year: 2008
Journal: Kidney Int
Title: Nephrin is involved in podocyte maturation but not survival during glomerular development.
Volume: 73
Issue: 6
Pages: 697-704
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Publication
24717294 | J:238264
First Author: Clar J
Year: 2014
Journal: Kidney Int
Title: Targeted deletion of kidney glucose-6 phosphatase leads to nephropathy.
Volume: 86
Issue: 4
Pages: 747-56
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Publication
21406566 | J:182970
First Author: Saarikangas J
Year: 2011
Journal: J Cell Sci
Title: Missing-in-metastasis MIM/MTSS1 promotes actin assembly at intercellular junctions and is required for integrity of kidney epithelia.
Volume: 124
Issue: Pt 8
Pages: 1245-55
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Publication
23559562 | J:198192
First Author: Huang J
Year: 2013
Journal: Dev Dyn
Title: The transcription factor Sry-related HMG box-4 (SOX4) is required for normal renal development in vivo.
Volume: 242
Issue: 6
Pages: 790-9
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Publication
29113990 | J:253680
First Author: Chung E
Year: 2017
Journal: Development
Title: Notch is required for the formation of all nephron segments and primes nephron progenitors for differentiation.
Volume: 144
Issue: 24
Pages: 4530-4539
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Publication
18082680 | J:130822
First Author: Kanasaki K
Year: 2008
Journal: Dev Biol
Title: Integrin beta1-mediated matrix assembly and signaling are critical for the normal development and function of the kidney glomerulus.
Volume: 313
Issue: 2
Pages: 584-93
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Publication
21606590 | J:174022
First Author: Jeansson M
Year: 2011
Journal: J Clin Invest
Title: Angiopoietin-1 is essential in mouse vasculature during development and in response to injury.
Volume: 121
Issue: 6
Pages: 2278-89
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Publication
21521738 | J:171425
First Author: Marciano DK
Year: 2011
Journal: Development
Title: p120 catenin is required for normal renal tubulogenesis and glomerulogenesis.
Volume: 138
Issue: 10
Pages: 2099-109
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Publication
27591083 | J:255143
First Author: Rasouly HM
Year: 2016
Journal: Kidney Int
Title: Loss of Zeb2 in mesenchyme-derived nephrons causes primary glomerulocystic disease.
Volume: 90
Issue: 6
Pages: 1262-1273
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Publication
28334964 | J:242320
First Author: Kosfeld A
Year: 2017
Journal: Hum Mol Genet
Title: Mutations in the leukemia inhibitory factor receptor (LIFR) gene and Lifr deficiency cause urinary tract malformations.
Volume: 26
Issue: 9
Pages: 1716-1731
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Publication
16177003 | J:150394
First Author: Jouret F
Year: 2005
Journal: J Am Soc Nephrol
Title: Ubiquitous and kidney-specific subunits of vacuolar H+-ATPase are differentially expressed during nephrogenesis.
Volume: 16
Issue: 11
Pages: 3235-46
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Publication
29449453 | J:273779
First Author: Lindström NO
Year: 2018
Journal: J Am Soc Nephrol
Title: Conserved and Divergent Features of Human and Mouse Kidney Organogenesis.
Volume: 29
Issue: 3
Pages: 785-805
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Publication
18787044 | J:142530
First Author: Pitera JE
Year: 2008
Journal: Hum Mol Genet
Title: Fras1, a basement membrane-associated protein mutated in Fraser syndrome, mediates both the initiation of the mammalian kidney and the integrity of renal glomeruli.
Volume: 17
Issue: 24
Pages: 3953-64
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Publication
36445780 | J:333146
 
First Author: Kumar S
Year: 2023
Journal: JCI Insight
Title: ZEB2 controls kidney stromal progenitor differentiation and inhibits abnormal myofibroblast expansion and kidney fibrosis.
Volume: 8
Issue: 1
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Publication
16498405 | J:106710
First Author: Takemoto M
Year: 2006
Journal: EMBO J
Title: Large-scale identification of genes implicated in kidney glomerulus development and function.
Volume: 25
Issue: 5
Pages: 1160-74
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Publication
32715478 | J:300975
First Author: Weiss AC
Year: 2020
Journal: J Pathol
Title: Expansion of the renal capsular stroma, ureteric bud branching defects and cryptorchidism in mice with Wilms tumor 1 gene deletion in the stromal compartment of the developing kidney.
Volume: 252
Issue: 3
Pages: 290-303
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Publication
35341793 | J:333283
First Author: Guan N
Year: 2022
Journal: Kidney Int
Title: Disruption of mitochondrial complex III in cap mesenchyme but not in ureteric progenitors results in defective nephrogenesis associated with amino acid deficiency.
Volume: 102
Issue: 1
Pages: 108-120
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Publication
21931791 | J:177885
First Author: Brunskill EW
Year: 2011
Journal: PLoS One
Title: Defining the molecular character of the developing and adult kidney podocyte.
Volume: 6
Issue: 9
Pages: e24640
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Publication
32179912 | J:288446
First Author: Christians A
Year: 2020
Journal: Hum Mol Genet
Title: Inflammation-like changes in the urothelium of Lifr-deficient mice and LIFR-haploinsufficient humans with urinary tract anomalies.
Volume: 29
Issue: 7
Pages: 1192-1204
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Publication
29459093 | J:309384
First Author: Neirijnck Y
Year: 2018
Journal: Kidney Int
Title: Sox11 gene disruption causes congenital anomalies of the kidney and urinary tract (CAKUT).
Volume: 93
Issue: 5
Pages: 1142-1153
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Publication
30377232 | J:291050
First Author: Ide S
Year: 2018
Journal: J Am Soc Nephrol
Title: Transcription Factor 21 Is Required for Branching Morphogenesis and Regulates the Gdnf-Axis in Kidney Development.
Volume: 29
Issue: 12
Pages: 2795-2808
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Publication
28527294 | J:243840
First Author: Gerl K
Year: 2017
Journal: Am J Pathol
Title: Activation of Hypoxia Signaling in Stromal Progenitors Impairs Kidney Development.
Volume: 187
Issue: 7
Pages: 1496-1511
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Publication
28535371 | J:241850
First Author: Naiman N
Year: 2017
Journal: Dev Cell
Title: Repression of Interstitial Identity in Nephron Progenitor Cells by Pax2 Establishes the Nephron-Interstitium Boundary during Kidney Development.
Volume: 41
Issue: 4
Pages: 349-365.e3
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:171409
     
First Author: GUDMAP Consortium
Year: 2004
Journal: www.gudmap.org
Title: GUDMAP: the GenitoUrinary Development Molecular Anatomy Project
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2023-02-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2823928
Stage: TS28
Assay Id: MGI:7439177
Age: postnatal adult
Image: 2B Eltd1 bottom
Note: Expression did not colocalize with Nphs2 in the podocytes.
Specimen Label: 2B Eltd1 bottom
Detected: false
Specimen Num: 7
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Allele
Nphs2<em1Smoc> | MGI:7265005
Name: nephrosis 2, podocin; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Nphs2<em2Smoc> | MGI:7265006
Name: nephrosis 2, podocin; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Not Specified
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Allele
Nphs2<em3Smoc> | MGI:7265007
Name: nephrosis 2, podocin; endonuclease-mediated mutation 3, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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DO Term
DOID:0080379 | nephrotic syndrome type 2
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Gene
7225 | TRPC6
Type: gene
Organism: human
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Allele
Nphs2<tm1(cre/ERT2)Smoc> | MGI:6758036
Name: nephrosis 2, podocin; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Inducible, Recombinase
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Strain
MGI:6475895 | C57BL/6-Nphs2<em3Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Allele
Tg(NPHS2-cre)295Lbh | MGI:2450359
Name: transgene insertion 295, Lawrence B Holzman
Allele Type: Transgenic
Attribute String: Recombinase
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Gene
51196 | PLCE1
Type: gene
Organism: human
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Strain
MGI:6354508 | C57BL/6-Nphs2<tm1(cre/ERT2)Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Strain
MGI:4437893 | 129S6.Cg-Tg(NPHS2-cre)295Lbh/BroJ
Attribute String: mutant strain, transgenic, congenic
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Strain
MGI:3844275 | B6.Cg-Tg(NPHS2-cre)295Lbh/J
Attribute String: congenic, transgenic
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Publication
15784842 | J:134739
First Author: Moeller MJ
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: An efficient system for tissue-specific overexpression of transgenes in podocytes in vivo.
Volume: 289
Issue: 2
Pages: F481-8
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Publication
30810063 | J:285845
First Author: Balkawade RS
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Podocyte-specific expression of Cre recombinase promotes glomerular basement membrane thickening.
Volume: 316
Issue: 5
Pages: F1026-F1040
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Publication
20562105 | J:165990
First Author: Kaufman L
Year: 2010
Journal: J Biol Chem
Title: Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosis.
Volume: 285
Issue: 33
Pages: 25677-85
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Publication
22249312 | J:183428
First Author: Boucher I
Year: 2012
Journal: Lab Invest
Title: Gα12 activation in podocytes leads to cumulative changes in glomerular collagen expression, proteinuria and glomerulosclerosis.
Volume: 92
Issue: 5
Pages: 662-75
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Allele
Tg(NPHS2-rtTA2*M2)1Jbk | MGI:3629962
Name: transgene insertion 1, Jeffrey B Kopp
Allele Type: Transgenic
Attribute String: Transactivator
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Genotype
Genotype
Symbol: Tg(NPHS2-cre)295Lbh/?
Background: 129S6.Cg-Tg(NPHS2-cre)295Lbh/BroJ
Zygosity: ot
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Tg(NPHS2-cre)295Lbh/Tg(NPHS2-cre)295Lbh
Background: 129S6.Cg-Tg(NPHS2-cre)295Lbh/BroJ
Zygosity: hm
Has Mutant Allele: true
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Publication
12481297 | J:81633
First Author: Moeller MJ
Year: 2003
Journal: Genesis
Title: Podocyte-specific expression of cre recombinase in transgenic mice.
Volume: 35
Issue: 1
Pages: 39-42
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Publication
20641128 | J:162633
First Author: Wang J
Year: 2010
Journal: Genesis
Title: Tamoxifen-inducible podocyte-specific iCre recombinase transgenic mouse provides a simple approach for modulation of podocytes in vivo.
Volume: 48
Issue: 7
Pages: 446-51
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Publication
35396346 | J:325405
First Author: Matoba K
Year: 2022
Journal: Commun Biol
Title: ROCK2-induced metabolic rewiring in diabetic podocytopathy.
Volume: 5
Issue: 1
Pages: 341
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Publication
28352079 | J:275262
First Author: Hsu MF
Year: 2017
Journal: Sci Rep
Title: Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria.
Volume: 7
Issue: 1
Pages: 461
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Publication
35342338 | J:322948
First Author: Li MR
Year: 2022
Journal: Int J Biol Sci
Title: MAD2B promotes podocyte injury through regulating Numb-dependent Notch 1 pathway in diabetic nephropathy.
Volume: 18
Issue: 5
Pages: 1896-1911
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Publication
29720549 | J:290115
First Author: Artelt N
Year: 2018
Journal: J Am Soc Nephrol
Title: The Role of Palladin in Podocytes.
Volume: 29
Issue: 6
Pages: 1662-1678
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Publication
34879092 | J:317431
First Author: Artelt N
Year: 2021
Journal: PLoS One
Title: The podocyte-specific knockout of palladin in mice with a 129 genetic background affects podocyte morphology and the expression of palladin interacting proteins.
Volume: 16
Issue: 12
Pages: e0260878
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Strain
MGI:3776159 | FVB/N-Tg(NPHS2-rtTA2*M2)1Jbk/J
Attribute String: coisogenic, transgenic
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Publication
17625119 | J:148150
First Author: Davis B
Year: 2007
Journal: J Am Soc Nephrol
Title: Podocyte-specific expression of angiopoietin-2 causes proteinuria and apoptosis of glomerular endothelia.
Volume: 18
Issue: 8
Pages: 2320-9
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Publication
23954273 | J:201883
First Author: Reidy KJ
Year: 2013
Journal: Am J Pathol
Title: Excess podocyte semaphorin-3A leads to glomerular disease involving plexinA1-nephrin interaction.
Volume: 183
Issue: 4
Pages: 1156-68
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Publication
18647955 | J:141994
First Author: Ku CH
Year: 2008
Journal: Diabetes
Title: Inducible overexpression of sFlt-1 in podocytes ameliorates glomerulopathy in diabetic mice.
Volume: 57
Issue: 10
Pages: 2824-33
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Genotype
Genotype
Symbol: Ldb1/Ldb1 Tg(NPHS2-cre)295Lbh/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Agrn/Agrn Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Jaml/Jaml Tg(NPHS2-cre)295Lbh/?
Background: B6.Cg-Jaml Tg(NPHS2-cre)295Lbh
Zygosity: cn
Has Mutant Allele: true
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Publication
17316599 | J:122505
First Author: Suleiman H
Year: 2007
Journal: Dev Biol
Title: The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes.
Volume: 304
Issue: 2
Pages: 701-12
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Gene
7941 | PLA2G7
Type: gene
Organism: human
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Publication
20472933 | J:165315
First Author: Garg P
Year: 2010
Journal: J Biol Chem
Title: Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture.
Volume: 285
Issue: 29
Pages: 22676-88
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Publication
26644409 | J:236136
First Author: Verma R
Year: 2015
Journal: Mol Cell Biol
Title: Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury.
Volume: 36
Issue: 4
Pages: 596-614
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Allele
Tg(NPHS2-cre/ERT2)#Hika | MGI:6728122
Name: transgene insertion, Hiroshi Kawachi
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
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Publication
22975019 | J:190128
First Author: Brähler S
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria.
Volume: 303
Issue: 10
Pages: F1473-85
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Publication
26268269 | J:280490
First Author: Brähler S
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: The NF-κB essential modulator (NEMO) controls podocyte cytoskeletal dynamics independently of NF-κB.
Volume: 309
Issue: 7
Pages: F617-26
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Publication
16611717 | J:129244
First Author: El-Aouni C
Year: 2006
Journal: J Am Soc Nephrol
Title: Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.
Volume: 17
Issue: 5
Pages: 1334-44
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Publication
16837631 | J:129286
First Author: Dai C
Year: 2006
Journal: J Am Soc Nephrol
Title: Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling.
Volume: 17
Issue: 8
Pages: 2164-75
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Publication
20375988 | J:184271
First Author: Dai C
Year: 2010
Journal: Kidney Int
Title: Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria.
Volume: 77
Issue: 11
Pages: 962-73
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Publication
33761352 | J:312325
First Author: Maier JI
Year: 2021
Journal: Cell Rep
Title: EPB41L5 controls podocyte extracellular matrix assembly by adhesome-dependent force transmission.
Volume: 34
Issue: 12
Pages: 108883
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Publication
22034640 | J:232697
First Author: Riediger F
Year: 2011
Journal: J Am Soc Nephrol
Title: Prorenin receptor is essential for podocyte autophagy and survival.
Volume: 22
Issue: 12
Pages: 2193-202
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Genotype
Genotype
Symbol: Ilk/Ilk Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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