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Search results 101 to 149 out of 149 for Xirp2

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Type Details Score
Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Allele
Xirp2<tm1Itl> | MGI:4947971
Name: xin actin-binding repeat containing 2; targeted mutation 1, inGenious Targeting Laboratory
Allele Type: Targeted
Attribute String: Conditional ready, Hypomorph
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Allele
Xirp2<tm1.1Itl> | MGI:4947972
Name: xin actin-binding repeat containing 2; targeted mutation 1.1, inGenious Targeting Laboratory
Allele Type: Targeted
Attribute String: Hypomorph
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Publication
20940435 | -
First Author: Ottenheijm CA
Year: 2010
Journal: Physiology (Bethesda)
Title: Lifting the nebula: novel insights into skeletal muscle contractility.
Volume: 25
Issue: 5
Pages: 304-10
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Publication
26792324 | -
First Author: Chu M
Year: 2016
Journal: J Exp Biol
Title: Nebulin, a multi-functional giant.
Volume: 219
Issue: Pt 2
Pages: 146-52
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Publication
32470469 | J:292146
 
First Author: Chen Y
Year: 2020
Journal: J Mol Cell Cardiol
Title: Identifying modifier genes for hypertrophic cardiomyopathy.
Volume: 144
Pages: 119-126
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Publication
14657273 | J:87879
First Author: Carroll S
Year: 2004
Journal: J Cell Sci
Title: N-RAP scaffolds I-Z-I assembly during myofibrillogenesis in cultured chick cardiomyocytes.
Volume: 117
Issue: Pt 1
Pages: 105-14
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Publication
11739655 | -
First Author: Carroll SL
Year: 2001
Journal: J Cell Sci
Title: Targeting and functional role of N-RAP, a nebulin-related LIM protein, during myofibril assembly in cultured chick cardiomyocytes.
Volume: 114
Issue: Pt 23
Pages: 4229-38
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Protein Domain
IPR035629 | Nebulin_SH3
Type: Domain
Description: Nebulin is a giant filamentous protein (600-900 kD) that plays a role in numerous cellular processes including regulation of muscle contraction, Z-disc formation, and myofibril organization and assembly in skeletal muscle. It contains an N-terminal LIM domain, many nebulin repeats/super repeats, and a C-terminal SH3 domain. The N terminus of nebulin is located near the pointed end of the thin filament and contains a binding site for the actin filament capping protein tropomodulin (Tmod). The super repeat region of nebulin has been shown to interact with kelch-like family member 40 (KLHL40). The C terminus of nebulin is located within the highly specialized boundary of the sarcomere (Z-disc), and plays an important role in myofibril assembly, mechanosensing, signaling, force generation and transmission, and sarcolemmal resilience. The SH3 domain of nebulin interacts with multiple proteins, such as alpha-actinin, XIRP2 and titin []. Mutations in nebulin can cause nemaline myopathy, characterised by muscle weakness which can be severe and can lead to neonatal lethality []. This entry represents the SH3 domain of Nebulin.
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Protein Domain
IPR013998 | Nebulin-like
Type: Family
Description: This entry include nebulin and nebulin-related-anchoring protein (N-RAP). Nebulin is a giant filamentous protein (600-900 kD) that plays a role in numerous cellular processes including regulation of muscle contraction, Z-disc formation, and myofibril organization and assembly in skeletal muscle. It contains an N-terminal LIM domain, many nebulin repeats/super repeats, and a C-terminal SH3 domain. The N terminus of nebulin is located near the pointed end of the thin filament and contains a binding site for the actin filament capping protein tropomodulin (Tmod). The super repeat region of nebulin has been shown to interact with kelch-like family member 40 (KLHL40). The C terminus of nebulin is located within the highly specialized boundary of the sarcomere (Z-disc), and plays an important role in myofibril assembly, mechanosensing, signaling, force generation and transmission, and sarcolemmal resilience. The SH3 domain of nebulin interacts with multiple proteins, such as alpha-actinin, XIRP2 and titin []. Mutations in nebulin can cause nemaline myopathy, characterised by muscle weakness which can be severe and can lead to neonatal lethality []. Nebulin-related-anchoring protein (N-RAP) is a muscle-specific protein that may serve as a scaffold for premyofibril assembly [, ]. N-RAP contains a N-terminal LIM domain (LIM), the C-terminal actin-binding nebulin super repeats and the nebulin-related simple repeats (IB) in between the two []. The N-terminal IB region is essential for alpha-actinin organisation, while the N-RAP super repeats are essential for sarcomeric actin organisation [].
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Publication
12692149 | J:83790
First Author: Lu S
Year: 2003
Journal: J Cell Sci
Title: New N-RAP-binding partners alpha-actinin, filamin and Krp1 detected by yeast two-hybrid screening: implications for myofibril assembly.
Volume: 116
Issue: Pt 11
Pages: 2169-78
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Protein
Q8C3C3
Organism: Mus musculus/domesticus
Length: 354  
Fragment?: true
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Protein
A0A1B0GSI0
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: true
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Protein
F6RDH3
Organism: Mus musculus/domesticus
Length: 1190  
Fragment?: true
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Protein
Q62412
Organism: Mus musculus/domesticus
Length: 1190  
Fragment?: true
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Protein
G3UWS1
Organism: Mus musculus/domesticus
Length: 342  
Fragment?: true
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Protein
Q61953
Organism: Mus musculus/domesticus
Length: 424  
Fragment?: true
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Protein
F7CXG1
Organism: Mus musculus/domesticus
Length: 387  
Fragment?: true
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Protein
Q62411
Organism: Mus musculus/domesticus
Length: 1358  
Fragment?: true
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Protein
A0A571BF46
Organism: Mus musculus/domesticus
Length: 7488  
Fragment?: false
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Protein
A0A571BF58
Organism: Mus musculus/domesticus
Length: 7523  
Fragment?: false
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Protein
A2AQA9
Organism: Mus musculus/domesticus
Length: 6909  
Fragment?: false
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Protein
A2AQB2
Organism: Mus musculus/domesticus
Length: 3044  
Fragment?: false
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Protein
E9Q1W3
Organism: Mus musculus/domesticus
Length: 7152  
Fragment?: false
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Protein
Q80XB4
Organism: Mus musculus/domesticus
Length: 1728  
Fragment?: false
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Protein
E9PZF4
Organism: Mus musculus/domesticus
Length: 1692  
Fragment?: false
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Protein
F6X9B6
Organism: Mus musculus/domesticus
Length: 768  
Fragment?: true
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Protein
Q9JL90
Organism: Mus musculus/domesticus
Length: 768  
Fragment?: true
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Protein
E9Q641
Organism: Mus musculus/domesticus
Length: 1485  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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