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Search results 1 to 100 out of 111 for Idh2

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Category: Publication
Type Details Score
Publication  
First Author: Wang H
Year: 2023
Journal: Metabolism
Title: Hepatic IDH2 regulates glycolysis and gluconeogenesis.
Volume: 143
Pages: 155559
Publication
First Author: Kats LM
Year: 2014
Journal: Cell Stem Cell
Title: Proto-oncogenic role of mutant IDH2 in leukemia initiation and maintenance.
Volume: 14
Issue: 3
Pages: 329-41
Publication  
First Author: Ku HJ
Year: 2015
Journal: Free Radic Biol Med
Title: IDH2 deficiency promotes mitochondrial dysfunction and cardiac hypertrophy in mice.
Volume: 80
Pages: 84-92
Publication  
First Author: Park JH
Year: 2018
Journal: Redox Biol
Title: IDH2 deficiency accelerates skin pigmentation in mice via enhancing melanogenesis.
Volume: 17
Pages: 16-24
Publication
First Author: Lee SJ
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Idh2 deficiency accelerates renal dysfunction in aged mice.
Volume: 493
Issue: 1
Pages: 34-39
Publication
First Author: White K
Year: 2018
Journal: Sci Rep
Title: Loss of IDH2 Accelerates Age-related Hearing Loss in Male Mice.
Volume: 8
Issue: 1
Pages: 5039
Publication
First Author: Zhang X
Year: 2020
Journal: Blood
Title: Dnmt3a loss and Idh2 neomorphic mutations mutually potentiate malignant hematopoiesis.
Volume: 135
Issue: 11
Pages: 845-856
Publication
First Author: Kim SH
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: IDH2 deficiency impairs cutaneous wound healing via ROS-dependent apoptosis.
Volume: 1865
Issue: 11
Pages: 165523
Publication
First Author: Kim H
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: IDH2 deficiency exacerbates acetaminophen hepatotoxicity in mice via mitochondrial dysfunction-induced apoptosis.
Volume: 1865
Issue: 9
Pages: 2333-2341
Publication
First Author: Gong F
Year: 2019
Journal: Biochem Biophys Res Commun
Title: IDH2 protects against nonalcoholic steatohepatitis by alleviating dyslipidemia regulated by oxidative stress.
Volume: 514
Issue: 3
Pages: 593-600
Publication
First Author: Park JH
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Disruption of IDH2 attenuates lipopolysaccharide-induced inflammation and lung injury in an α-ketoglutarate-dependent manner.
Volume: 503
Issue: 2
Pages: 798-802
Publication  
First Author: Lee SH
Year: 2019
Journal: Bone
Title: IDH2 deficiency increases bone mass with reduced osteoclastogenesis by limiting RANKL expression in osteoblasts.
Volume: 129
Pages: 115056
Publication  
First Author: Pan JH
Year: 2020
Journal: Int J Mol Sci
Title: IDH2 Deficiency Is Critical in Myogenesis and Fatty Acid Metabolism in Mice Skeletal Muscle.
Volume: 21
Issue: 16
Publication
First Author: Chen TC
Year: 2022
Journal: Oncogene
Title: Oncogenesis induced by combined Phf6 and Idh2 mutations through increased oncometabolites and impaired DNA repair.
Volume: 41
Issue: 11
Pages: 1576-1588
Publication
First Author: Leca J
Year: 2023
Journal: Cancer Cell
Title: IDH2 and TET2 mutations synergize to modulate T Follicular Helper cell functional interaction with the AITL microenvironment.
Volume: 41
Issue: 2
Pages: 323-339.e10
Publication
First Author: Lemonnier F
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development.
Volume: 113
Issue: 52
Pages: 15084-15089
Publication  
First Author: Han YK
Year: 2021
Journal: Redox Biol
Title: Oxidative stress following acute kidney injury causes disruption of lung cell cilia and their release into the bronchoaveolar lavage fluid and lung injury, which are exacerbated by Idh2 deletion.
Volume: 46
Pages: 102077
Publication
First Author: Chae U
Year: 2018
Journal: Physiol Res
Title: IDH2-deficient mice develop spinal deformities with aging.
Volume: 67
Issue: 3
Pages: 487-494
Publication
First Author: Kim S
Year: 2022
Journal: Commun Biol
Title: miR204 potentially promotes non-alcoholic fatty liver disease by inhibition of cpt1a in mouse hepatocytes.
Volume: 5
Issue: 1
Pages: 1002
Publication  
First Author: Cha H
Year: 2017
Journal: Redox Biol
Title: Increased susceptibility of IDH2-deficient mice to dextran sodium sulfate-induced colitis.
Volume: 13
Pages: 32-38
Publication  
First Author: Lee SJ
Year: 2016
Journal: Free Radic Biol Med
Title: Increased obesity resistance and insulin sensitivity in mice lacking the isocitrate dehydrogenase 2 gene.
Volume: 99
Pages: 179-188
Publication
First Author: Han SJ
Year: 2017
Journal: J Am Soc Nephrol
Title: Mitochondrial NADP+-Dependent Isocitrate Dehydrogenase Deficiency Exacerbates Mitochondrial and Cell Damage after Kidney Ischemia-Reperfusion Injury.
Volume: 28
Issue: 4
Pages: 1200-1215
Publication
First Author: Choi SJ
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Isocitrate dehydrogenase 2 deficiency induces endothelial inflammation via p66sh-mediated mitochondrial oxidative stress.
Volume: 503
Issue: 3
Pages: 1805-1811
Publication  
First Author: Pan JH
Year: 2019
Journal: Genes (Basel)
Title: Hepatic Transcriptomics Reveals that Lipogenesis Is a Key Signaling Pathway in Isocitrate Dehydrogenase 2 Deficient Mice.
Volume: 10
Issue: 9
Publication
First Author: Karlstaedt A
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Oncometabolite d-2-hydroxyglutarate impairs α-ketoglutarate dehydrogenase and contractile function in rodent heart.
Volume: 113
Issue: 37
Pages: 10436-41
Publication
First Author: Fortin J
Year: 2023
Journal: Proc Natl Acad Sci U S A
Title: Distinct and opposite effects of leukemogenic Idh and Tet2 mutations in hematopoietic stem and progenitor cells.
Volume: 120
Issue: 4
Pages: e2208176120
Publication
First Author: Ku HJ
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Isocitrate dehydrogenase 2 deficiency exacerbates dermis damage by ultraviolet-B via ΔNp63 downregulation.
Volume: 1864
Issue: 4 Pt A
Pages: 1138-1147
Publication
First Author: Savoia M
Year: 2019
Journal: FASEB J
Title: P300/CBP-associated factor regulates transcription and function of isocitrate dehydrogenase 2 during muscle differentiation.
Volume: 33
Issue: 3
Pages: 4107-4123
Publication
First Author: Shih AH
Year: 2017
Journal: Cancer Discov
Title: Combination Targeted Therapy to Disrupt Aberrant Oncogenic Signaling and Reverse Epigenetic Dysfunction in IDH2- and TET2-Mutant Acute Myeloid Leukemia.
Volume: 7
Issue: 5
Pages: 494-505
Publication
First Author: Chae U
Year: 2019
Journal: Aging (Albany NY)
Title: Reactive oxygen species-mediated senescence is accelerated by inhibiting Cdk2 in Idh2-deficient conditions.
Volume: 11
Issue: 17
Pages: 7242-7256
Publication
First Author: Yoshimi A
Year: 2019
Journal: Nature
Title: Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis.
Volume: 574
Issue: 7777
Pages: 273-277
Publication
First Author: Jo SH
Year: 2001
Journal: J Biol Chem
Title: Control of mitochondrial redox balance and cellular defense against oxidative damage by mitochondrial NADP+-dependent isocitrate dehydrogenase.
Volume: 276
Issue: 19
Pages: 16168-76
Publication  
First Author: Britton-Davidian J
Year: 1983
Journal: Mouse News Lett
Title: Linkage data in chromosome 7
Volume: 68
Pages: 79
Publication
First Author: Yang L
Year: 1996
Journal: J Cell Biochem
Title: Molecular cloning of the cDNA of mouse mitochondrial NADP-dependent isocitrate dehydrogenase and the expression of the gene during lymphocyte activation.
Volume: 60
Issue: 3
Pages: 400-10
Publication
First Author: Lu Q
Year: 2008
Journal: Arch Biochem Biophys
Title: Dual compartmental localization and function of mammalian NADP+-specific isocitrate dehydrogenase in yeast.
Volume: 472
Issue: 1
Pages: 17-25
Publication
First Author: Lalley PA
Year: 1978
Journal: Cytogenet Cell Genet
Title: Comparative gene mapping in man and mouse: assignment of the genes for lactate dehydrogenase-A, peptidase-D, and isocitrate dehydrogenase-2 to mouse chromosome 7.
Volume: 22
Issue: 1-6
Pages: 577-80
Publication  
First Author: Lalley PA
Year: 1979
Journal: Cytogenet Cell Genet
Title: Comparative mapping in man and mouse involving genes assigned to human chromosomes 11, 15, 19, and X.
Volume: 25
Pages: 177 (Abstr.)
Publication
First Author: Izzo F
Year: 2020
Journal: Nat Genet
Title: DNA methylation disruption reshapes the hematopoietic differentiation landscape.
Volume: 52
Issue: 4
Pages: 378-387
Publication
First Author: Kim S
Year: 2014
Journal: Biochim Biophys Acta
Title: Suppression of tumorigenesis in mitochondrial NADP(+)-dependent isocitrate dehydrogenase knock-out mice.
Volume: 1842
Issue: 2
Pages: 135-43
Publication  
First Author: Bogdanovic E
Year: 2014
Journal: Neurosci Lett
Title: IDH1 regulates phospholipid metabolism in developing astrocytes.
Volume: 582
Pages: 87-92
Publication
First Author: Lalley PA
Year: 1978
Journal: Nature
Title: Conservation of autosomal gene synteny groups in mouse and man.
Volume: 274
Issue: 5667
Pages: 160-3
Publication
First Author: Crespo I
Year: 2015
Journal: Am J Pathol
Title: Molecular and Genomic Alterations in Glioblastoma Multiforme.
Volume: 185
Issue: 7
Pages: 1820-33
Publication
First Author: Krog HH
Year: 1977
Journal: Hereditas
Title: Genetic characterization of important mouse strains used in cancer research.
Volume: 87
Issue: 2
Pages: 201-4
Publication
First Author: Stallings RL
Year: 1981
Journal: Somatic Cell Genet
Title: Confirmational, provisional, and/or regional assignment of 15 enzyme loci onto Chinese hamster autosomes 1, 2, and 7.
Volume: 7
Issue: 6
Pages: 683-98
Publication
First Author: Bonhomme F
Year: 1984
Journal: Biochem Genet
Title: Biochemical diversity and evolution in the genus Mus.
Volume: 22
Issue: 3-4
Pages: 275-303
Publication
First Author: Chong D
Year: 2022
Journal: Cell Discov
Title: Neonatal ketone body elevation regulates postnatal heart development by promoting cardiomyocyte mitochondrial maturation and metabolic reprogramming.
Volume: 8
Issue: 1
Pages: 106
Publication  
First Author: Cankaya M
Year: 2007
Journal: BMC Genomics
Title: An analysis of expression patterns of genes encoding proteins with catalytic activities.
Volume: 8
Pages: 232
Publication
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
Publication
First Author: Da Cruz S
Year: 2003
Journal: J Biol Chem
Title: Proteomic analysis of the mouse liver mitochondrial inner membrane.
Volume: 278
Issue: 42
Pages: 41566-71
Publication
First Author: Bulusu V
Year: 2017
Journal: Dev Cell
Title: Spatiotemporal Analysis of a Glycolytic Activity Gradient Linked to Mouse Embryo Mesoderm Development.
Volume: 40
Issue: 4
Pages: 331-341.e4
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
Publication
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
Publication      
First Author: Freeman TC
Year: 1998
Journal: MGI Direct Data Submission
Title: Expression Mapping of Mouse Genes
Publication
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
Publication      
First Author: NIH Mouse Knockout Inventory
Year: 2004
Journal: MGI Direct Data Submission
Title: Information obtained from the NIH Mouse Knockout Inventory
Publication        
First Author: International Committee on Standardized Genetic Nomenclature for Mice
Year: 1993
Title: Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols
Publication
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
Publication
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
Publication
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
Publication
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
Publication
First Author: Visel A
Year: 2004
Journal: Nucleic Acids Res
Title: GenePaint.org: an atlas of gene expression patterns in the mouse embryo.
Volume: 32
Issue: Database issue
Pages: D552-6
Publication      
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Akbay EA
Year: 2014
Journal: Genes Dev
Title: D-2-hydroxyglutarate produced by mutant IDH2 causes cardiomyopathy and neurodegeneration in mice.
Volume: 28
Issue: 5
Pages: 479-90
Publication
First Author: Zhou L
Year: 2016
Journal: EMBO Rep
Title: SIRT5 promotes IDH2 desuccinylation and G6PD deglutarylation to enhance cellular antioxidant defense.
Volume: 17
Issue: 6
Pages: 811-22
Publication
First Author: Cupp JR
Year: 1991
Journal: J Biol Chem
Title: NAD(+)-dependent isocitrate dehydrogenase. Cloning, nucleotide sequence, and disruption of the IDH2 gene from Saccharomyces cerevisiae.
Volume: 266
Issue: 33
Pages: 22199-205
Publication
First Author: Goldberg L
Year: 2021
Journal: Cancer Res
Title: Mutant Idh2 Cooperates with a NUP98-HOXD13 Fusion to Induce Early Immature Thymocyte Precursor ALL.
Volume: 81
Issue: 19
Pages: 5033-5046
Publication
First Author: Saha SK
Year: 2014
Journal: Nature
Title: Mutant IDH inhibits HNF-4α to block hepatocyte differentiation and promote biliary cancer.
Volume: 513
Issue: 7516
Pages: 110-4
Publication
First Author: Waitkus MS
Year: 2018
Journal: Cancer Cell
Title: Biological Role and Therapeutic Potential of IDH Mutations in Cancer.
Volume: 34
Issue: 2
Pages: 186-195
Publication
First Author: Zhang H
Year: 2019
Journal: Nat Commun
Title: Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.
Volume: 10
Issue: 1
Pages: 244
Publication
First Author: Someya S
Year: 2010
Journal: Cell
Title: Sirt3 mediates reduction of oxidative damage and prevention of age-related hearing loss under caloric restriction.
Volume: 143
Issue: 5
Pages: 802-12
Publication
First Author: Wang Y
Year: 2015
Journal: Mol Cell
Title: WT1 recruits TET2 to regulate its target gene expression and suppress leukemia cell proliferation.
Volume: 57
Issue: 4
Pages: 662-73