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Search results 1 to 100 out of 251 for Ctsk

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Category: Publication
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Type Details Score
Publication
32212276 | J:311501
First Author: Li Q
Year: 2020
Journal: J Bone Miner Res
Title: Ubiquitin-Specific Protease 34 Inhibits Osteoclast Differentiation by Regulating NF-κB Signaling.
Volume: 35
Issue: 8
Pages: 1597-1608
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Publication
25958043 | J:225929
 
First Author: Sinnesael M
Year: 2015
Journal: Mol Cell Endocrinol
Title: The androgen receptor has no direct antiresorptive actions in mouse osteoclasts.
Volume: 411
Pages: 198-206
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Publication
25896020 | J:221174
First Author: Hao L
Year: 2015
Journal: FEBS Lett
Title: Deficiency of cathepsin K prevents inflammation and bone erosion in rheumatoid arthritis and periodontitis and reveals its shared osteoimmune role.
Volume: 589
Issue: 12
Pages: 1331-1339
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Publication
23321671 | J:194492
First Author: Lotinun S
Year: 2013
Journal: J Clin Invest
Title: Osteoclast-specific cathepsin K deletion stimulates S1P-dependent bone formation.
Volume: 123
Issue: 2
Pages: 666-81
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Publication
31112135 | J:289620
First Author: Lotinun S
Year: 2019
Journal: J Clin Invest
Title: Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression.
Volume: 129
Issue: 8
Pages: 3058-3071
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Publication
17668061 | J:129317
First Author: Funicello M
Year: 2007
Journal: PLoS One
Title: Cathepsin K null mice show reduced adiposity during the rapid accumulation of fat stores.
Volume: 2
Issue: 8
Pages: e683
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Publication
31065924 | J:294308
First Author: Zhao R
Year: 2019
Journal: Cell Mol Neurobiol
Title: Cathepsin K Knockout Exacerbates Haemorrhagic Transformation Induced by Recombinant Tissue Plasminogen Activator After Focal Cerebral Ischaemia in Mice.
Volume: 39
Issue: 6
Pages: 823-831
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Publication
20230792 | J:159232
First Author: Zenger S
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Long bone osteoclasts display an augmented osteoclast phenotype compared to calvarial osteoclasts.
Volume: 394
Issue: 3
Pages: 743-9
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Publication
28095448 | J:248530
First Author: Jiang T
Year: 2017
Journal: PLoS One
Title: Distribution of Cathepsin K in Late Stage of Tooth Germ Development and Its Function in Degrading Enamel Matrix Proteins in Mouse.
Volume: 12
Issue: 1
Pages: e0169857
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Publication
29880809 | J:314812
First Author: Guo R
Year: 2018
Journal: Cell Death Dis
Title: Cardiomyocyte-specific disruption of Cathepsin K protects against doxorubicin-induced cardiotoxicity.
Volume: 9
Issue: 6
Pages: 692
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Publication
15664014 | J:95525
First Author: Kiviranta R
Year: 2005
Journal: Bone
Title: Impaired bone resorption in cathepsin K-deficient mice is partially compensated for by enhanced osteoclastogenesis and increased expression of other proteases via an increased RANKL/OPG ratio.
Volume: 36
Issue: 1
Pages: 159-72
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Publication
16753017 | J:128098
First Author: Li CY
Year: 2006
Journal: J Bone Miner Res
Title: Mice lacking cathepsin K maintain bone remodeling but develop bone fragility despite high bone mass.
Volume: 21
Issue: 6
Pages: 865-75
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Publication
30850734 | J:298399
First Author: Li R
Year: 2019
Journal: Cell Death Differ
Title: Gut microbiota-stimulated cathepsin K secretion mediates TLR4-dependent M2 macrophage polarization and promotes tumor metastasis in colorectal cancer.
Volume: 26
Issue: 11
Pages: 2447-2463
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Publication
34183355 | J:310826
First Author: Khan IZ
Year: 2021
Journal: Cancer Res
Title: The CD200-CD200R Axis Promotes Squamous Cell Carcinoma Metastasis via Regulation of Cathepsin K.
Volume: 81
Issue: 19
Pages: 5021-5032
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Publication
10372556 | J:55345
First Author: Rantakokko J
Year: 1999
Journal: Matrix Biol
Title: Complete genomic structure of the mouse cathepsin K gene (Ctsk) and its localization next to the Arnt gene on mouse chromosome 3.
Volume: 18
Issue: 2
Pages: 155-61
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Publication
36147479 | J:329286
First Author: Zhu G
Year: 2022
Journal: Int J Biol Sci
Title: Knockout and Double Knockout of Cathepsin K and Mmp9 reveals a novel function of Cathepsin K as a regulator of osteoclast gene expression and bone homeostasis.
Volume: 18
Issue: 14
Pages: 5522-5538
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Publication
34742737 | J:334709
First Author: Yu J
Year: 2021
Journal: J Biol Chem
Title: Hairy and enhancer of split 1 is a primary effector of NOTCH2 signaling and induces osteoclast differentiation and function.
Volume: 297
Issue: 6
Pages: 101376
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Publication
31134061 | J:284399
 
First Author: Csete D
Year: 2019
Journal: Front Immunol
Title: Hematopoietic or Osteoclast-Specific Deletion of Syk Leads to Increased Bone Mass in Experimental Mice.
Volume: 10
Pages: 937
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Publication
30075049 | J:325973
First Author: Pohl S
Year: 2018
Journal: J Bone Miner Res
Title: The Lysosomal Protein Arylsulfatase B Is a Key Enzyme Involved in Skeletal Turnover.
Volume: 33
Issue: 12
Pages: 2186-2201
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Publication
19661463 | J:169972
First Author: Combs MD
Year: 2009
Journal: Circ Res
Title: VEGF and RANKL regulation of NFATc1 in heart valve development.
Volume: 105
Issue: 6
Pages: 565-74
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21447555 | J:171274
First Author: Combs MD
Year: 2011
Journal: Development
Title: NFATC1 promotes epicardium-derived cell invasion into myocardium.
Volume: 138
Issue: 9
Pages: 1747-57
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Publication
16680826 | J:109487
First Author: Lange AW
Year: 2006
Journal: Dev Biol
Title: NFATc1 expression in the developing heart valves is responsive to the RANKL pathway and is required for endocardial expression of cathepsin K.
Volume: 292
Issue: 2
Pages: 407-17
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Publication
12652657 | J:106181
First Author: Chiellini C
Year: 2003
Journal: J Cell Physiol
Title: Identification of cathepsin K as a novel marker of adiposity in white adipose tissue.
Volume: 195
Issue: 2
Pages: 309-21
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8814310 | J:35370
First Author: Rantakokko J
Year: 1996
Journal: FEBS Lett
Title: Mouse cathepsin K: cDNA cloning and predominant expression of the gene in osteoclasts, and in some hypertrophying chondrocytes during mouse development.
Volume: 393
Issue: 2-3
Pages: 307-13
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Publication
17210673 | J:117870
First Author: Chen W
Year: 2007
Journal: Hum Mol Genet
Title: Novel pycnodysostosis mouse model uncovers cathepsin K function as a potential regulator of osteoclast apoptosis and senescence.
Volume: 16
Issue: 4
Pages: 410-23
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Publication
31808010 | J:332715
First Author: Dauth S
Year: 2020
Journal: Cell Mol Neurobiol
Title: Function of Cathepsin K in the Central Nervous System of Male Mice is Independent of Its Role in the Thyroid Gland.
Volume: 40
Issue: 5
Pages: 695-710
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Publication
23152408 | J:320786
First Author: Arampatzidou M
Year: 2012
Journal: Biol Chem
Title: Effects of cathepsin K deficiency on intercellular junction proteins, luminal mucus layers, and extracellular matrix constituents in the mouse colon.
Volume: 393
Issue: 12
Pages: 1391-403
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Publication
29800693 | J:266619
 
First Author: Yang P
Year: 2018
Journal: Bone
Title: Preservation of type H vessels and osteoblasts by enhanced preosteoclast platelet-derived growth factor type BB attenuates glucocorticoid-induced osteoporosis in growing mice.
Volume: 114
Pages: 1-13
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Publication
15161653 | J:109717
First Author: Bühling F
Year: 2004
Journal: Am J Pathol
Title: Pivotal role of cathepsin K in lung fibrosis.
Volume: 164
Issue: 6
Pages: 2203-16
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Publication
24928497 | J:215505
 
First Author: Gentile MA
Year: 2014
Journal: Bone
Title: Increased fracture callus mineralization and strength in cathepsin K knockout mice.
Volume: 66
Pages: 72-81
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Publication
21817099 | J:194802
First Author: Sun J
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Cathepsin K deficiency reduces elastase perfusion-induced abdominal aortic aneurysms in mice.
Volume: 32
Issue: 1
Pages: 15-23
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Publication
23529168 | J:268788
First Author: Hua Y
Year: 2013
Journal: Hypertension
Title: Cathepsin K knockout alleviates pressure overload-induced cardiac hypertrophy.
Volume: 61
Issue: 6
Pages: 1184-92
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Publication
26460818 | J:309069
First Author: Moriya S
Year: 2016
Journal: J Cell Physiol
Title: Cathepsin K Deficiency Suppresses Disuse-Induced Bone Loss.
Volume: 231
Issue: 5
Pages: 1163-70
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Publication
22484689 | J:186212
First Author: Hayami T
Year: 2012
Journal: Bone
Title: Inhibition of cathepsin K reduces cartilage degeneration in the anterior cruciate ligament transection rabbit and murine models of osteoarthritis.
Volume: 50
Issue: 6
Pages: 1250-9
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Publication
18845279 | J:146026
First Author: Pennypacker B
Year: 2009
Journal: Bone
Title: Bone density, strength, and formation in adult cathepsin K (-/-) mice.
Volume: 44
Issue: 2
Pages: 199-207
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15826870 | J:99669
First Author: Morko J
Year: 2005
Journal: Bone
Title: Differential turnover of cortical and trabecular bone in transgenic mice overexpressing cathepsin K.
Volume: 36
Issue: 5
Pages: 854-65
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37948912 | J:343371
 
First Author: Yamaguchi H
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Enhanced BMP signaling in Cathepsin K-positive tendon progenitors induces heterotopic ossification.
Volume: 688
Pages: 149147
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23269702 | J:194359
First Author: Yang C
Year: 2013
Journal: Cancer Discov
Title: Antagonism of inhibitor of apoptosis proteins increases bone metastasis via unexpected osteoclast activation.
Volume: 3
Issue: 2
Pages: 212-23
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24590570 | J:234751
First Author: Jacome-Galarza C
Year: 2014
Journal: J Cell Biochem
Title: Altered hematopoietic stem cell and osteoclast precursor frequency in cathepsin K null mice.
Volume: 115
Issue: 8
Pages: 1449-57
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Publication
34327196 | J:321400
 
First Author: Pánczél Á
Year: 2021
Journal: Front Cell Dev Biol
Title: Fluorescence-Based Real-Time Analysis of Osteoclast Development.
Volume: 9
Pages: 657935
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25951977 | J:228464
First Author: Rahman MM
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Secretion of PDGF isoforms during osteoclastogenesis and its modulation by anti-osteoclast drugs.
Volume: 462
Issue: 2
Pages: 159-64
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21968827 | J:233286
First Author: Kozawa E
Year: 2012
Journal: Arthritis Rheum
Title: Osteoarthritic change is delayed in a Ctsk-knockout mouse model of osteoarthritis.
Volume: 64
Issue: 2
Pages: 454-64
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25692548 | J:222030
First Author: Hua Y
Year: 2015
Journal: Aging Cell
Title: Cathepsin K knockout alleviates aging-induced cardiac dysfunction.
Volume: 14
Issue: 3
Pages: 345-51
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Publication
24894568 | J:274177
 
First Author: Jiang H
Year: 2014
Journal: Nat Commun
Title: Cathepsin K-mediated Notch1 activation contributes to neovascularization in response to hypoxia.
Volume: 5
Pages: 3838
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Publication
23069627 | J:208613
First Author: Hua Y
Year: 2013
Journal: Diabetes
Title: Cathepsin K knockout mitigates high-fat diet-induced cardiac hypertrophy and contractile dysfunction.
Volume: 62
Issue: 2
Pages: 498-509
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Publication
24343118 | J:280766
First Author: Hu L
Year: 2014
Journal: Hypertension
Title: Cathepsin K activity controls injury-related vascular repair in mice.
Volume: 63
Issue: 3
Pages: 607-15
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Publication
21718816 | J:176984
First Author: Leung P
Year: 2011
Journal: Bone
Title: The effects of the cathepsin K inhibitor odanacatib on osteoclastic bone resorption and vesicular trafficking.
Volume: 49
Issue: 4
Pages: 623-35
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Publication
28821796 | J:255813
First Author: Guo R
Year: 2017
Journal: Sci Rep
Title: Cathepsin K knockout protects against cardiac dysfunction in diabetic mice.
Volume: 7
Issue: 1
Pages: 8703
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Publication
11082042 | J:66887
 
First Author: Tepel C
Year: 2000
Journal: J Cell Sci
Title: Cathepsin K in thyroid epithelial cells: sequence, localization and possible function in extracellular proteolysis of thyroglobulin.
Volume: 113 Pt 24
Pages: 4487-98
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Publication
8703060 | J:47500
First Author: Gelb BD
Year: 1996
Journal: Science
Title: Pycnodysostosis, a lysosomal disease caused by cathepsin K deficiency.
Volume: 273
Issue: 5279
Pages: 1236-8
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8986645 | J:38441
First Author: Gelb BD
Year: 1996
Journal: Biochem Mol Med
Title: Cathepsin K: isolation and characterization of the murine cDNA and genomic sequence, the homologue of the human pycnodysostosis gene.
Volume: 59
Issue: 2
Pages: 200-6
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9556067 | J:47097
First Author: Dodds RA
Year: 1998
Journal: J Bone Miner Res
Title: Cathepsin K mRNA detection is restricted to osteoclasts during fetal mouse development.
Volume: 13
Issue: 4
Pages: 673-82
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10234569 | J:54282
First Author: Li YP
Year: 1999
Journal: J Bone Miner Res
Title: Characterization of mouse cathepsin K gene, the gene promoter, and the gene expression.
Volume: 14
Issue: 4
Pages: 487-99
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15265002 | J:94063
First Author: Godat E
Year: 2004
Journal: Biochem J
Title: Cathepsin K: a cysteine protease with unique kinin-degrading properties.
Volume: 383
Issue: Pt. 3
Pages: 501-6
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16329095 | J:133863
First Author: Morko J
Year: 2005
Journal: Arthritis Rheum
Title: Spontaneous development of synovitis and cartilage degeneration in transgenic mice overexpressing cathepsin K.
Volume: 52
Issue: 12
Pages: 3713-7
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19700761 | J:153118
First Author: Podgorski I
Year: 2009
Journal: Am J Pathol
Title: Bone marrow-derived cathepsin K cleaves SPARC in bone metastasis.
Volume: 175
Issue: 3
Pages: 1255-69
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32853181 | J:309035
First Author: Feng H
Year: 2020
Journal: J Clin Invest
Title: Tendon-derived cathepsin K-expressing progenitor cells activate Hedgehog signaling to drive heterotopic ossification.
Volume: 130
Issue: 12
Pages: 6354-6365
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9811821 | J:50934
First Author: Saftig P
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Impaired osteoclastic bone resorption leads to osteopetrosis in cathepsin-K-deficient mice.
Volume: 95
Issue: 23
Pages: 13453-8
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19834056 | J:154691
First Author: Wilson S
Year: 2009
Journal: Am J Pathol
Title: Glycosaminoglycan-mediated loss of cathepsin K collagenolytic activity in MPS I contributes to osteoclast and growth plate abnormalities.
Volume: 175
Issue: 5
Pages: 2053-62
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23341620 | J:193823
First Author: Coury F
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: SLC4A2-mediated Cl-/HCO3- exchange activity is essential for calpain-dependent regulation of the actin cytoskeleton in osteoclasts.
Volume: 110
Issue: 6
Pages: 2163-8
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22308398 | J:182617
First Author: Tsuji-Takechi K
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Stage-specific functions of leukemia/lymphoma-related factor (LRF) in the transcriptional control of osteoclast development.
Volume: 109
Issue: 7
Pages: 2561-6
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23526406 | J:233252
First Author: Nagai Y
Year: 2013
Journal: J Bone Miner Res
Title: p130Cas, Crk-associated substrate, plays important roles in osteoclastic bone resorption.
Volume: 28
Issue: 12
Pages: 2449-62
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11472890 | J:167697
First Author: Yamaza T
Year: 2001
Journal: Bone
Title: Comparison in localization between cystatin C and cathepsin K in osteoclasts and other cells in mouse tibia epiphysis by immunolight and immunoelectron microscopy.
Volume: 29
Issue: 1
Pages: 42-53
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27636705 | J:251282
First Author: Donners MM
Year: 2016
Journal: PLoS One
Title: Cathepsin K Deficiency Prevents the Aggravated Vascular Remodeling Response to Flow Cessation in ApoE-/- Mice.
Volume: 11
Issue: 9
Pages: e0162595
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16365196 | J:121514
First Author: Lutgens E
Year: 2006
Journal: Circulation
Title: Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation.
Volume: 113
Issue: 1
Pages: 98-107
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19028686 | J:146945
First Author: Wilson SR
Year: 2009
Journal: J Biol Chem
Title: Cathepsin K activity-dependent regulation of osteoclast actin ring formation and bone resorption.
Volume: 284
Issue: 4
Pages: 2584-92
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20203298 | J:180871
First Author: Samokhin AO
Year: 2010
Journal: Arterioscler Thromb Vasc Biol
Title: Cholate-containing high-fat diet induces the formation of multinucleated giant cells in atherosclerotic plaques of apolipoprotein E-/- mice.
Volume: 30
Issue: 6
Pages: 1166-73
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16972305 | J:115163
First Author: Lutgens SP
Year: 2006
Journal: J Pathol
Title: Gene profiling of cathepsin K deficiency in atherogenesis: profibrotic but lipogenic.
Volume: 210
Issue: 3
Pages: 334-43
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18818416 | J:159791
First Author: Yang M
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: Deficiency and inhibition of cathepsin K reduce body weight gain and increase glucose metabolism in mice.
Volume: 28
Issue: 12
Pages: 2202-8
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Publication
33486152 | J:310339
 
First Author: Weng Y
Year: 2021
Journal: Redox Biol
Title: Trem2 mediated Syk-dependent ROS amplification is essential for osteoclastogenesis in periodontitis microenvironment.
Volume: 40
Pages: 101849
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30659979 | J:273280
 
First Author: Tsang K
Year: 2019
Journal: Bone
Title: Defective circadian control in mesenchymal cells reduces adult bone mass in mice by promoting osteoclast function.
Volume: 121
Pages: 172-180
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28177161 | J:276277
First Author: Nakamichi Y
Year: 2017
Journal: J Bone Miner Res
Title: VDR in Osteoblast-Lineage Cells Primarily Mediates Vitamin D Treatment-Induced Increase in Bone Mass by Suppressing Bone Resorption.
Volume: 32
Issue: 6
Pages: 1297-1308
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25737953 | J:220976
First Author: Ma C
Year: 2015
Journal: Mol Metab
Title: Genetic determination of the cellular basis of the ghrelin-dependent bone remodeling.
Volume: 4
Issue: 3
Pages: 175-85
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24938130 | J:219434
First Author: Yu TY
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Aryl hydrocarbon receptor catabolic activity in bone metabolism is osteoclast dependent in vivo.
Volume: 450
Issue: 1
Pages: 416-22
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33607650 | J:303673
First Author: Zhu M
Year: 2021
Journal: PLoS One
Title: Selective deletion of the receptor for CSF1, c-fms, in osteoclasts results in a high bone mass phenotype, smaller osteoclasts in vivo and an impaired response to an anabolic PTH regimen.
Volume: 16
Issue: 2
Pages: e0247199
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29358671 | J:303477
First Author: Xu S
Year: 2018
Journal: Cell Death Differ
Title: TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42.
Volume: 25
Issue: 9
Pages: 1549-1566
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Publication
33605542 | J:329409
First Author: Shalev M
Year: 2021
Journal: FEBS J
Title: PTPRJ promotes osteoclast maturation and activity by inhibiting Cbl-mediated ubiquitination of NFATc1 in late osteoclastogenesis.
Volume: 288
Issue: 15
Pages: 4702-4723
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27677594 | J:252544
 
First Author: Hirozane T
Year: 2016
Journal: Sci Rep
Title: Conditional abrogation of Atm in osteoclasts extends osteoclast lifespan and results in reduced bone mass.
Volume: 6
Pages: 34426
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30250253 | J:266610
First Author: Debnath S
Year: 2018
Journal: Nature
Title: Discovery of a periosteal stem cell mediating intramembranous bone formation.
Volume: 562
Issue: 7725
Pages: 133-139
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32582715 | J:303381
 
First Author: Li S
Year: 2020
Journal: Front Cell Dev Biol
Title: Conditional Knockout of PKC-δ in Osteoclasts Favors Bone Mass Accrual in Males Due to Decreased Osteoclast Function.
Volume: 8
Pages: 450
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Publication
31919867 | J:291961
First Author: Roberts JL
Year: 2020
Journal: Ann N Y Acad Sci
Title: Deletion of Wnt5a in osteoclasts results in bone loss through decreased bone formation.
Volume: 1463
Issue: 1
Pages: 45-59
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Publication
22308018 | J:285787
First Author: Qing H
Year: 2012
Journal: J Bone Miner Res
Title: Demonstration of osteocytic perilacunar/canalicular remodeling in mice during lactation.
Volume: 27
Issue: 5
Pages: 1018-29
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Publication
20039311 | J:161253
First Author: Mizoguchi F
Year: 2010
Journal: J Cell Biochem
Title: Osteoclast-specific Dicer gene deficiency suppresses osteoclastic bone resorption.
Volume: 109
Issue: 5
Pages: 866-75
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Publication
31941964 | J:283710
First Author: Wang L
Year: 2020
Journal: Nat Commun
Title: Mechanical sensing protein PIEZO1 regulates bone homeostasis via osteoblast-osteoclast crosstalk.
Volume: 11
Issue: 1
Pages: 282
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Publication
24327965 | J:221302
First Author: Lacombe J
Year: 2013
Journal: Mol Metab
Title: In vivo analysis of the contribution of bone resorption to the control of glucose metabolism in mice.
Volume: 2
Issue: 4
Pages: 498-504
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Publication
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