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Search results 501 to 600 out of 911 for Traf6

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Protein
A2AR78
Organism: Mus musculus/domesticus
Length: 360  
Fragment?: false
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Publication
21931631 | -
First Author: Goncalves A
Year: 2011
Journal: PLoS One
Title: Functional dissection of the TBK1 molecular network.
Volume: 6
Issue: 9
Pages: e23971
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Protein Domain
IPR037307 | TRAF4_MATH
Type: Domain
Description: TNF receptor-associated factor 4 (TRAF4) is an adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. TRAF4 plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. It regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. TRAF4 modulates TRAF6 functions [, , , , , ]. In mouse, it has been shown to be required for normal skeleton development, and for normal development of the respiratory tract []. TRAF4 contains a RING finger domain, seven zinc finger domains, and a TRAF domain.The TRAF domain can be divided into a more divergent N-terminal alpha helical region (TRAF-N), and a highly conserved C-terminal MATH subdomain (TRAF-C) with an eight-stranded β-sandwich structure. TRAF-N mediates trimerization while TRAF-C interacts with receptors [, ].
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Protein Coding Gene
MGI:1341909 | Ly96
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:98217 | S100b
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914853 | Dusp6
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1914495 | Peli1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1346862 | Mapk9
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1346868 | Map2k3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1346869 | Map2k4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1919216 | Nkiras2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1919599 | Dusp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:95574 | Fos
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1920336 | Rps6ka5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1916971 | Nkiras1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2445060 | Lrrc14
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1298366 | Atf1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:893592 | Ager
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2147032 | Ticam1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1346878 | Map3k8
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1928898 | Usp14
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:88318 | Cd14
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3040056 | Ticam2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:109349 | Atf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1918731 | Alpk1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2182965 | Tifa
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96824 | Tlr4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96646 | Jun
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2386643 | Tnip2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1346863 | Mapk10
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:96113 | Hmgb1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1341839 | Nod1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2429603 | Irak2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1344364 | Usp18
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2182465 | Vrk3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1859179 | Irf3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:1346871 | Map2k7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2442191 | Dusp4
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2136825 | N4bp1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2429397 | Nod2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:3612191 | Nlrc5
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2429611 | Nlrx1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2387100 | Dusp7
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI:2143163 | Mapkapk3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q9CXB8
Organism: Mus musculus/domesticus
Length: 1231  
Fragment?: false
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Protein
Q9D7X3
Organism: Mus musculus/domesticus
Length: 185  
Fragment?: false
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Protein
Q62151
Organism: Mus musculus/domesticus
Length: 402  
Fragment?: false
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Protein
Q3UMW7
Organism: Mus musculus/domesticus
Length: 384  
Fragment?: false
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Protein
P05627
Organism: Mus musculus/domesticus
Length: 334  
Fragment?: false
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Protein
Q9WTU6
Organism: Mus musculus/domesticus
Length: 423  
Fragment?: false
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Protein
Q07174
Organism: Mus musculus/domesticus
Length: 467  
Fragment?: false
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Protein
Q61831
Organism: Mus musculus/domesticus
Length: 464  
Fragment?: false
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Protein
Q8CFA1
Organism: Mus musculus/domesticus
Length: 622  
Fragment?: false
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Protein
Q8CE90
Organism: Mus musculus/domesticus
Length: 535  
Fragment?: false
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Protein
Q8BFV3
Organism: Mus musculus/domesticus
Length: 398  
Fragment?: false
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Protein
Q3TL44
Organism: Mus musculus/domesticus
Length: 975  
Fragment?: false
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Protein
Q8C050
Organism: Mus musculus/domesticus
Length: 863  
Fragment?: false
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Protein
C3VPR6
Organism: Mus musculus/domesticus
Length: 1915  
Fragment?: false
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Protein
P63158
Organism: Mus musculus/domesticus
Length: 215  
Fragment?: false
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Protein
Q8C669
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: false
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Protein
Q8BHB0
Organism: Mus musculus/domesticus
Length: 953  
Fragment?: false
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Protein
P01101
Organism: Mus musculus/domesticus
Length: 380  
Fragment?: false
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Protein
Q91Z46
Organism: Mus musculus/domesticus
Length: 422  
Fragment?: false
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Protein
Q9DBB1
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: false
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Protein
Q9JHF9
Organism: Mus musculus/domesticus
Length: 160  
Fragment?: false
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Protein
P81269
Organism: Mus musculus/domesticus
Length: 269  
Fragment?: false
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Protein
Q8K3Z0
Organism: Mus musculus/domesticus
Length: 1020  
Fragment?: false
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Protein
P10810
Organism: Mus musculus/domesticus
Length: 366  
Fragment?: false
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Protein
Q9CR56
Organism: Mus musculus/domesticus
Length: 191  
Fragment?: false
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Protein
P70671
Organism: Mus musculus/domesticus
Length: 419  
Fragment?: false
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Protein
O09110
Organism: Mus musculus/domesticus
Length: 347  
Fragment?: false
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Protein
P47809
Organism: Mus musculus/domesticus
Length: 397  
Fragment?: false
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Protein
Q8VC16
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
Q8CEC5
Organism: Mus musculus/domesticus
Length: 192  
Fragment?: false
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Protein
P50114
Organism: Mus musculus/domesticus
Length: 92  
Fragment?: false
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Protein
P16951
Organism: Mus musculus/domesticus
Length: 487  
Fragment?: false
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Protein
Q80UF7
Organism: Mus musculus/domesticus
Length: 732  
Fragment?: false
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Protein
Q99JG7
Organism: Mus musculus/domesticus
Length: 430  
Fragment?: false
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Protein
Q9QUK6
Organism: Mus musculus/domesticus
Length: 835  
Fragment?: false
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Protein
Q8BJQ4
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: false
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Protein
Q9WTV6
Organism: Mus musculus/domesticus
Length: 368  
Fragment?: false
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Protein
Q8K3G5
Organism: Mus musculus/domesticus
Length: 453  
Fragment?: false
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Protein
Q9JMA1
Organism: Mus musculus/domesticus
Length: 493  
Fragment?: false
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Protein
Q6A037
Organism: Mus musculus/domesticus
Length: 893  
Fragment?: false
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Publication
16157600 | J:163137
First Author: Abell AN
Year: 2005
Journal: J Biol Chem
Title: MEKK4 is an effector of the embryonic TRAF4 for JNK activation.
Volume: 280
Issue: 43
Pages: 35793-6
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Publication
11098060 | -
First Author: Leo E
Year: 2001
Journal: J Biol Chem
Title: TRAF1 is a substrate of caspases activated during tumor necrosis factor receptor-alpha-induced apoptosis.
Volume: 276
Issue: 11
Pages: 8087-93
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Publication
9847406 | -
First Author: Wajant H
Year: 1998
Journal: J Mol Evol
Title: Identification of a TRAF (TNF receptor-associated factor) gene in Caenorhabditis elegans.
Volume: 47
Issue: 6
Pages: 656-62
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Publication
9744859 | -
First Author: Arch RH
Year: 1998
Journal: Genes Dev
Title: Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death.
Volume: 12
Issue: 18
Pages: 2821-30
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Publication
10021364 | -
First Author: Liu H
Year: 1999
Journal: Curr Biol
Title: A Drosophila TNF-receptor-associated factor (TRAF) binds the ste20 kinase Misshapen and activates Jun kinase.
Volume: 9
Issue: 2
Pages: 101-4
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Publication
24012418 | J:208213
First Author: Xia M
Year: 2013
Journal: Immunity
Title: Histone methyltransferase Ash1l suppresses interleukin-6 production and inflammatory autoimmune diseases by inducing the ubiquitin-editing enzyme A20.
Volume: 39
Issue: 3
Pages: 470-81
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Publication
17438001 | J:121114
First Author: Grabiner BC
Year: 2007
Journal: Genes Dev
Title: CARMA3 deficiency abrogates G protein-coupled receptor-induced NF-{kappa}B activation.
Volume: 21
Issue: 8
Pages: 984-96
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Publication
22044243 | J:181390
First Author: Portillo JA
Year: 2012
Journal: Immunology
Title: CD40 and tumour necrosis factor-α co-operate to up-regulate inducuble nitric oxide synthase expression in macrophages.
Volume: 135
Issue: 2
Pages: 140-50
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Publication
26414765 | J:258700
First Author: Geng J
Year: 2015
Journal: Nat Immunol
Title: Kinases Mst1 and Mst2 positively regulate phagocytic induction of reactive oxygen species and bactericidal activity.
Volume: 16
Issue: 11
Pages: 1142-52
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Publication
30996248 | J:275578
First Author: Ben J
Year: 2019
Journal: Nat Commun
Title: Major vault protein suppresses obesity and atherosclerosis through inhibiting IKK-NF-κB signaling mediated inflammation.
Volume: 10
Issue: 1
Pages: 1801
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Publication
36577385 | J:340918
First Author: Veras FP
Year: 2022
Journal: Cell Rep
Title: Pyruvate kinase M2 mediates IL-17 signaling in keratinocytes driving psoriatic skin inflammation.
Volume: 41
Issue: 13
Pages: 111897
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Publication
33893298 | J:306089
First Author: Garo LP
Year: 2021
Journal: Nat Commun
Title: MicroRNA-146a limits tumorigenic inflammation in colorectal cancer.
Volume: 12
Issue: 1
Pages: 2419
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Publication
21703540 | J:173995
First Author: Allen IC
Year: 2011
Journal: Immunity
Title: NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways.
Volume: 34
Issue: 6
Pages: 854-65
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Publication
23001144 | J:188566
First Author: Yan D
Year: 2012
Journal: Nat Immunol
Title: Inhibition of TLR signaling by a bacterial protein containing immunoreceptor tyrosine-based inhibitory motifs.
Volume: 13
Issue: 11
Pages: 1063-71
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Publication
26932182 | J:266713
 
First Author: Guo M
Year: 2016
Journal: Sci Rep
Title: Cyclophilin A (CypA) Plays Dual Roles in Regulation of Bone Anabolism and Resorption.
Volume: 6
Pages: 22378
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Publication
12619928 | J:111298
First Author: Kanazawa K
Year: 2003
Journal: J Bone Miner Res
Title: TRAF5 functions in both RANKL- and TNFalpha-induced osteoclastogenesis.
Volume: 18
Issue: 3
Pages: 443-50
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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