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Search results 501 to 548 out of 548 for Tle3

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0.021s
Type Details Score
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
GXD Expression
Probe: MGI:6441164
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6441170
Age: embryonic day 17.5
Image: 1A
Note: Many Gcg-positive alpha-cells were Tle3 negative or had low-level nuclear Tle3 expression.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6441165
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6441181
Age: embryonic day 17.5
Image: 1A
Note: The majority of insulin-positive b-cells expressed Tle3. Many Gcg-positive alpha-cells were Tle3 negative or had low-level nuclear Tle3 expression.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6441165
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-14
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750325
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:6441475
Age: embryonic day 17.5
Image: 1A
Note: The majority of insulin-positive b-cells expressed Tle3. Many Gcg-positive alpha-cells were Tle3 negative or had low-level nuclear Tle3 expression.
Specimen Label: 1A
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6441164
Assay Type: Immunohistochemistry
Annotation Date: 2020-07-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6441170
Age: postnatal adult
Image: 1B right
Note: The majority of Gcg-positive alpha-cells were Tle3 negative. The percentage of Tle3+ alpha-cells decreased from E17.5 (47%) to the adult (14%).
Specimen Label: 1B right
Detected: true
Specimen Num: 2
GO Term
Allele
Name: transgene insertion LU125, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
Strain
Attribute String: mutant stock, transgenic
Publication
First Author: Shooshtarizadeh P
Year: 2019
Journal: Nat Commun
Title: Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes.
Volume: 10
Issue: 1
Pages: 1270
Publication
First Author: Zhou S
Year: 2022
Journal: Stem Cell Reports
Title: UHRF1 interacts with snRNAs and regulates alternative splicing in mouse spermatogonial stem cells.
Volume: 17
Issue: 8
Pages: 1859-1873
Publication
First Author: Liu Y
Year: 1996
Journal: Genomics
Title: Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia.
Volume: 31
Issue: 1
Pages: 58-64
Publication
First Author: Wood TE
Year: 2019
Journal: Cell Rep
Title: The Pseudomonas aeruginosa T6SS Delivers a Periplasmic Toxin that Disrupts Bacterial Cell Morphology.
Volume: 29
Issue: 1
Pages: 187-201.e7
Publication
First Author: Flaugnatti N
Year: 2020
Journal: EMBO J
Title: Structural basis for loading and inhibition of a bacterial T6SS phospholipase effector by the VgrG spike.
Volume: 39
Issue: 11
Pages: e104129
Publication  
First Author: Berni B
Year: 2019
Journal: Front Microbiol
Title: A Type VI Secretion System Trans-Kingdom Effector Is Required for the Delivery of a Novel Antibacterial Toxin in Pseudomonas aeruginosa.
Volume: 10
Pages: 1218
Publication
First Author: Sana TG
Year: 2015
Journal: mBio
Title: Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network.
Volume: 6
Issue: 3
Pages: e00712
Protein Domain
Type: Domain
Description: Type VI secretion system (T6SS) appears to be confined to Proteobacteria. It is important for bacterial pathogenesis, but it is also found in non-pathogenic bacteria, suggesting that T6SS involvement is not limited to virulence []. T6SS was identified in Vibrio cholerae []and Pseudomonas aeruginosa [], and exports Hcp (Haemolysin-Coregulated Protein) and a class of proteins named Vgr (Val-Gly Repeats). In addition to Vgr and Hcp proteins, T6SS is characterised by the presence of an AAA+ Clp-like ATPase and of two additional genes icmF and dotU, encoding homologues of T4SS stabilising proteins []. Type VI secretion system spike protein VgrG2a and VgrG2b are homologous to (gp27)3-(gp5)3 phage-tail proteins, which is followed by a domain of unknown function (DUF2345). Unlike VgrG2a, VgrG2b belongs to a subclass of VgrG proteins, called evolved VgrGs that have an additional C-terminal extension with a putative zinc-dependent metallopeptidase domain. VrgG2b acts directly as an effector and promotes internalization by interacting with the host gamma-tubulin ring complex []. It also elicits toxicity also in the bacterial periplasm and disrupts bacterial cell morphology. This toxicity is counteracted by a cognate immunity protein []. In addition, it allows the delivery of the Tle3 antibacterial toxin to target cells where it exerts its toxicity [].This entry represents DUF2345, which is found in the C-terminal region of VgrG2a/b from Pseudomonas aeruginosa. This domain, present in both proteins, folds as a β-prism [, ].
Publication  
First Author: Lee WJ
Year: 2017
Journal: Biomed Res Int
Title: An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos.
Volume: 2017
Pages: 8932583
Publication
First Author: Pukatzki S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Identification of a conserved bacterial protein secretion system in Vibrio cholerae using the Dictyostelium host model system.
Volume: 103
Issue: 5
Pages: 1528-33
Publication
First Author: Sexton JA
Year: 2004
Journal: Infect Immun
Title: Legionella pneumophila DotU and IcmF are required for stability of the Dot/Icm complex.
Volume: 72
Issue: 10
Pages: 5983-92
Publication  
First Author: Boyer F
Year: 2009
Journal: BMC Genomics
Title: Dissecting the bacterial type VI secretion system by a genome wide in silico analysis: what can be learned from available microbial genomic resources?
Volume: 10
Pages: 104
Publication
First Author: Mougous JD
Year: 2006
Journal: Science
Title: A virulence locus of Pseudomonas aeruginosa encodes a protein secretion apparatus.
Volume: 312
Issue: 5779
Pages: 1526-30
Publication      
First Author: The Gene Expression Nervous System Atlas (GENSAT) Project, The Rockefeller University (New York, NY)
Year: 2005
Journal: Database Download
Title: MGI download of GENSAT transgene data