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Search results 1 to 100 out of 140 for Rhbdf2

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Categories

Hits by Strain

Hits by Category

Type Details Score
Gene
79651 | RHBDF2
Type: gene
Organism: human
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Gene
454905 | RHBDF2
Type: gene
Organism: chimpanzee
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Gene
517903 | RHBDF2
Type: gene
Organism: cattle
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Gene
417358 | RHBDF2
Type: gene
Organism: chicken
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Gene
707033 | RHBDF2
Type: gene
Organism: macaque, rhesus
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Gene
100036646 | rhbdf2
Type: gene
Organism: frog, western clawed
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Gene
303690 | Rhbdf2
Type: gene
Organism: rat
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Gene
483332 | RHBDF2
Type: gene
Organism: dog, domestic
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Protein Coding Gene
MGI:2442473 | Rhbdf2
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
30694569 | J:273061
First Author: Geesala R
Year: 2019
Journal: J Leukoc Biol
Title: Loss of RHBDF2 results in an early-onset spontaneous murine colitis.
Volume: 105
Issue: 4
Pages: 767-781
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Publication
32094386 | J:289667
First Author: Levy R
Year: 2020
Journal: Sci Rep
Title: A genome-wide association study in mice reveals a role for Rhbdf2 in skeletal homeostasis.
Volume: 10
Issue: 1
Pages: 3286
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Publication
29116018 | J:250259
First Author: Hosur V
Year: 2017
Journal: BMC Res Notes
Title: Tissue-specific role of RHBDF2 in cutaneous wound healing and hyperproliferative skin disease.
Volume: 10
Issue: 1
Pages: 573
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Publication
24825892 | J:211269
First Author: Hosur V
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Rhbdf2 mutations increase its protein stability and drive EGFR hyperactivation through enhanced secretion of amphiregulin.
Volume: 111
Issue: 21
Pages: E2200-9
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Publication
28655741 | J:244160
First Author: Hosur V
Year: 2017
Journal: Biol Open
Title: Genetic deletion of amphiregulin restores the normal skin phenotype in a mouse model of the human skin disease tylosis.
Volume: 6
Issue: 8
Pages: 1174-1179
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Publication
28128203 | J:244670
 
First Author: Maruthappu T
Year: 2017
Journal: Nat Commun
Title: Rhomboid family member 2 regulates cytoskeletal stress-associated Keratin 16.
Volume: 8
Pages: 14174
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Publication
29523849 | J:259696
First Author: Arcidiacono P
Year: 2018
Journal: Nat Commun
Title: p63 is a key regulator of iRHOM2 signalling in the keratinocyte stress response.
Volume: 9
Issue: 1
Pages: 1021
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Publication
25395669 | J:217394
First Author: Siggs OM
Year: 2014
Journal: Biol Open
Title: Genetic interaction implicates iRhom2 in the regulation of EGF receptor signalling in mice.
Volume: 3
Issue: 12
Pages: 1151-7
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Publication
28104813 | J:246731
First Author: Li X
Year: 2017
Journal: J Cell Sci
Title: Structural modeling defines transmembrane residues in ADAM17 that are crucial for Rhbdf2-ADAM17-dependent proteolysis.
Volume: 130
Issue: 5
Pages: 868-878
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Publication
23348744 | J:194483
First Author: Issuree PD
Year: 2013
Journal: J Clin Invest
Title: iRHOM2 is a critical pathogenic mediator of inflammatory arthritis.
Volume: 123
Issue: 2
Pages: 928-32
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Protein Coding Gene
MGP_CAROLIEiJ_G0017449 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0019433 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0019401 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0019372 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0019376 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0019182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2442473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0019825 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0018737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0019153 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0019265 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0019257 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0019335 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0019290 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0019864 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0018501 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0018789 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0018578 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0018294 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
29491382 | J:262722
First Author: Kim JH
Year: 2018
Journal: Sci Rep
Title: Role of iRhom2 in intestinal ischemia-reperfusion-mediated acute lung injury.
Volume: 8
Issue: 1
Pages: 3797
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Publication
31918923 | J:285442
 
First Author: Badenes M
Year: 2020
Journal: Mol Metab
Title: Deletion of iRhom2 protects against diet-induced obesity by increasing thermogenesis.
Volume: 31
Pages: 67-84
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Publication
- | J:213194
     
First Author: Zhang Z
Year: 2014
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for LosTNF
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Publication
33950315 | J:310482
First Author: Düsterhöft S
Year: 2021
Journal: Cell Mol Life Sci
Title: The iRhom homology domain is indispensable for ADAM17-mediated TNFα and EGF receptor ligand release.
Volume: 78
Issue: 11
Pages: 5015-5040
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Publication
- | J:220064
     
First Author: Zhang Z
Year: 2015
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for LosTNF2 (Last updated March 25, 2015)
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Publication
29155878 | J:256003
First Author: Luo WW
Year: 2017
Journal: PLoS Pathog
Title: iRhom2 is essential for innate immunity to RNA virus by antagonizing ER- and mitochondria-associated degradation of VISA.
Volume: 13
Issue: 11
Pages: e1006693
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Publication
10425919 | J:52604
First Author: Li SR
Year: 1999
Journal: Genet Res
Title: Uncv (uncovered): a new mutation causing hairloss on mouse chromosome 11.
Volume: 73
Issue: 3
Pages: 233-8
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Publication
12766798 | J:83830
First Author: Shi YZ
Year: 2003
Journal: Sheng Wu Hua Xue Yu Sheng Wu Wu Li Xue Bao (Shanghai)
Title: A high-resolution genetic and physical map of a mouse coat abnormality locus (Uncv).
Volume: 35
Issue: 5
Pages: 397-402
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Publication
32135161 | J:291967
 
First Author: Skurski J
Year: 2020
Journal: Metabolism
Title: Loss of iRhom2 accelerates fat gain and insulin resistance in diet-induced obesity despite reduced adipose tissue inflammation.
Volume: 106
Pages: 154194
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Publication
31662486 | J:280798
 
First Author: Sundaram B
Year: 2019
Journal: Sci Signal
Title: iRhom2 inhibits bile duct obstruction-induced liver fibrosis.
Volume: 12
Issue: 605
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Publication
30097271 | J:271775
First Author: Chaohui C
Year: 2018
Journal: Biochem Biophys Res Commun
Title: iRhom2 promotes atherosclerosis through macrophage inflammation and induction of oxidative stress.
Volume: 503
Issue: 3
Pages: 1897-1904
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Publication
32180551 | J:304194
 
First Author: Xu M
Year: 2020
Journal: Mol Metab
Title: Functional loss of inactive rhomboid-like protein 2 mitigates obesity by suppressing pro-inflammatory macrophage activation-triggered adipose inflammation.
Volume: 34
Pages: 112-123
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Publication
29415889 | J:315620
 
First Author: Barnette DN
Year: 2018
Journal: JCI Insight
Title: iRhom2-mediated proinflammatory signalling regulates heart repair following myocardial infarction.
Volume: 3
Issue: 3
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Publication
30165303 | J:313195
 
First Author: Chenxu G
Year: 2018
Journal: Redox Biol
Title: iRhom2 loss alleviates renal injury in long-term PM2.5-exposed mice by suppression of inflammation and oxidative stress.
Volume: 19
Pages: 147-157
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Publication
27393687 | J:319206
First Author: Yang L
Year: 2016
Journal: Arch Dermatol Res
Title: iRhom2 (Uncv) mutation blocks bulge stem cells assuming the fate of hair follicle.
Volume: 308
Issue: 7
Pages: 503-10
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GXD Expression
GXD Expression
   
Probe: MGI:5705736
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705765
Age: postnatal
Image: 2
Specimen Label: +/+ mcub/mcub
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5705736
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705765
Age: postnatal
Image: 2
Specimen Label: cub/cub mcub/mcub
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5705737
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705766
Age: postnatal
Image: 2
Specimen Label: +/+ mcub/mcub
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5705737
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705766
Age: postnatal
Image: 2
Specimen Label: cub/cub mcub/mcub
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5705738
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705767
Age: postnatal
Image: 2
Specimen Label: +/+ mcub/mcub
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5705738
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705767
Age: postnatal
Image: 2
Specimen Label: cub/cub mcub/mcub
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5705739
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705768
Age: postnatal
Image: 2
Specimen Label: +/+ mcub/mcub
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5705739
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705768
Age: postnatal
Image: 2
Specimen Label: cub/cub mcub/mcub
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5705740
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705769
Age: postnatal
Image: 2
Specimen Label: +/+ mcub/mcub
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5705740
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705769
Age: postnatal
Image: 2
Specimen Label: cub/cub mcub/mcub
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5705741
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705770
Age: postnatal
Image: 2
Specimen Label: +/+ mcub/mcub
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5705741
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705770
Age: postnatal
Image: 2
Specimen Label: cub/cub mcub/mcub
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5705742
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705773
Age: postnatal
Image: 2
Specimen Label: +/+ mcub/mcub
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5705742
Assay Type: RT-PCR
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1752528
Stage: TS28
Assay Id: MGI:5705773
Age: postnatal
Image: 2
Specimen Label: cub/cub mcub/mcub
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-28
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3649828
Stage: TS28
Assay Id: MGI:5705763
Age: postnatal week 2
Image: 3B (right)
Specimen Label: 3B (right)
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-28
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1752826
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:5705763
Age: embryonic day 18.5
Image: 3B (left)
Specimen Label: 3B (left)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3279328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5705763
Age: postnatal week 2
Image: 3B (right)
Specimen Label: 3B (right)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Assay Type: In situ reporter (knock in)
Annotation Date: 2016-01-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3279228
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5705763
Age: postnatal week 2
Image: 3B (right)
Specimen Label: 3B (right)
Detected: true
Specimen Num: 2
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Publication
21439629 | J:173119
First Author: Zettl M
Year: 2011
Journal: Cell
Title: Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling.
Volume: 145
Issue: 1
Pages: 79-91
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Publication
23969955 | J:203951
First Author: Christova Y
Year: 2013
Journal: EMBO Rep
Title: Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation.
Volume: 14
Issue: 10
Pages: 884-90
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Publication
29045841 | J:254204
First Author: Cavadas M
Year: 2017
Journal: Cell Rep
Title: Phosphorylation of iRhom2 Controls Stimulated Proteolytic Shedding by the Metalloprotease ADAM17/TACE.
Volume: 21
Issue: 3
Pages: 745-757
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Publication
34937930 | J:320534
First Author: Kubo S
Year: 2022
Journal: Nat Immunol
Title: Congenital iRHOM2 deficiency causes ADAM17 dysfunction and environmentally directed immunodysregulatory disease.
Volume: 23
Issue: 1
Pages: 75-85
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Publication
27428826 | J:259147
First Author: Luo WW
Year: 2016
Journal: Nat Immunol
Title: iRhom2 is essential for innate immunity to DNA viruses by mediating trafficking and stability of the adaptor STING.
Volume: 17
Issue: 9
Pages: 1057-66
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Publication
32646486 | J:291556
First Author: Hosur V
Year: 2020
Journal: Genome Biol
Title: Genes adapt to outsmart gene-targeting strategies in mutant mouse strains by skipping exons to reinitiate transcription and translation.
Volume: 21
Issue: 1
Pages: 168
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Publication
33576385 | J:341296
First Author: Hannemann C
Year: 2022
Journal: Cardiovasc Res
Title: Deficiency of inactive rhomboid protein 2 (iRhom2) attenuates diet-induced hyperlipidaemia and early atherogenesis.
Volume: 118
Issue: 1
Pages: 156-168
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Publication
33957124 | J:306272
   
First Author: Lora J
Year: 2021
Journal: J Biol Chem
Title: Targeted truncation of the ADAM17 cytoplasmic domain in mice results in protein destabilization and a hypomorphic phenotype.
Pages: 100733
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Publication
32103528 | J:304951
First Author: Tang B
Year: 2020
Journal: FASEB J
Title: Substrate-selective protein ectodomain shedding by ADAM17 and iRhom2 depends on their juxtamembrane and transmembrane domains.
Volume: 34
Issue: 4
Pages: 4956-4969
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Publication
28965953 | J:305773
First Author: Ge CX
Year: 2017
Journal: Biochem Biophys Res Commun
Title: iRhom2 deficiency relieves TNF-α associated hepatic dyslipidemia in long-term PM2.5-exposed mice.
Volume: 493
Issue: 4
Pages: 1402-1409
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Publication
29369823 | J:261790
First Author: Qing X
Year: 2018
Journal: J Clin Invest
Title: iRhom2 promotes lupus nephritis through TNF-α and EGFR signaling.
Volume: 128
Issue: 4
Pages: 1397-1412
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Publication
29897333 | J:264179
   
First Author: Oikonomidi I
Year: 2018
Journal: Elife
Title: iTAP, a novel iRhom interactor, controls TNF secretion by policing the stability of iRhom/TACE.
Volume: 7
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Publication
29897336 | J:264397
   
First Author: Künzel U
Year: 2018
Journal: Elife
Title: FRMD8 promotes inflammatory and growth factor signalling by stabilising the iRhom/ADAM17 sheddase complex.
Volume: 7
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Publication
28432785 | J:259889
   
First Author: Grieve AG
Year: 2017
Journal: Elife
Title: Phosphorylation of iRhom2 at the plasma membrane controls mammalian TACE-dependent inflammatory and growth factor signalling.
Volume: 6
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Publication
37282854 | J:338016
 
First Author: Rabinowitsch AI
Year: 2023
Journal: J Cell Sci
Title: Analysis of the function of ADAM17 in iRhom2 curly-bare and tylosis with esophageal cancer mutant mice.
Volume: 136
Issue: 13
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Publication
27601030 | J:247030
First Author: Qing X
Year: 2016
Journal: Eur J Immunol
Title: iRhom2 regulates CSF1R cell surface expression and non-steady state myelopoiesis in mice.
Volume: 46
Issue: 12
Pages: 2737-2748
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Publication
23801765 | J:198810
First Author: Maretzky T
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: iRhom2 controls the substrate selectivity of stimulated ADAM17-dependent ectodomain shedding.
Volume: 110
Issue: 28
Pages: 11433-8
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Publication
33227998 | J:303061
 
First Author: Fang R
Year: 2020
Journal: Int J Mol Sci
Title: Role of iRhoms 1 and 2 in Endochondral Ossification.
Volume: 21
Issue: 22
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Publication
32060096 | J:287404
First Author: Weskamp G
Year: 2020
Journal: J Biol Chem
Title: ADAM17 stabilizes its interacting partner inactive Rhomboid 2 (iRhom2) but not inactive Rhomboid 1 (iRhom1).
Volume: 295
Issue: 13
Pages: 4350-4358
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Publication
22246777 | J:179654
First Author: Adrain C
Year: 2012
Journal: Science
Title: Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE.
Volume: 335
Issue: 6065
Pages: 225-8
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Publication
30022999 | J:275895
 
First Author: Hosur V
Year: 2018
Journal: Front Genet
Title: RHBDF2-Regulated Growth Factor Signaling in a Rare Human Disease, Tylosis With Esophageal Cancer: What Can We Learn From Murine Models?
Volume: 9
Pages: 233
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Publication
22550345 | J:187583
First Author: Siggs OM
Year: 2012
Journal: Blood
Title: iRhom2 is required for the secretion of mouse TNFα.
Volume: 119
Issue: 24
Pages: 5769-71
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Publication
22246778 | J:179653
First Author: McIlwain DR
Year: 2012
Journal: Science
Title: iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS.
Volume: 335
Issue: 6065
Pages: 229-32
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Publication
25918388 | J:221411
First Author: Li X
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling.
Volume: 112
Issue: 19
Pages: 6080-5
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Publication
34613632 | J:317051
First Author: Tüshaus J
Year: 2021
Journal: FASEB J
Title: The pseudoprotease iRhom1 controls ectodomain shedding of membrane proteins in the nervous system.
Volume: 35
Issue: 11
Pages: e21962
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Publication
12573256 | J:82006
First Author: Johnson KR
Year: 2003
Journal: Genomics
Title: Curly bare (cub), a new mouse mutation on chromosome 11 causing skin and hair abnormalities, and a modifier gene (mcub) on chromosome 5.
Volume: 81
Issue: 1
Pages: 6-14
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Publication
29776906 | J:265993
First Author: Haxaire C
Year: 2018
Journal: Blood
Title: Blood-induced bone loss in murine hemophilic arthropathy is prevented by blocking the iRhom2/ADAM17/TNF-α pathway.
Volume: 132
Issue: 10
Pages: 1064-1074
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Publication
25546423 | J:228844
First Author: Leilei Y
Year: 2014
Journal: PLoS One
Title: iRhom2 mutation leads to aberrant hair follicle differentiation in mice.
Volume: 9
Issue: 12
Pages: e115114
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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