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Search results 201 to 300 out of 1081 for Htt

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Type Details Score
Publication
24948797 | J:212083
First Author: Wade BE
Year: 2014
Journal: J Neurosci
Title: Ubiquitin-activating enzyme activity contributes to differential accumulation of mutant huntingtin in brain and peripheral tissues.
Volume: 34
Issue: 25
Pages: 8411-22
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Publication
32820193 | J:294905
First Author: Mason MA
Year: 2020
Journal: Sci Rep
Title: Silencing Srsf6 does not modulate incomplete splicing of the huntingtin gene in Huntington's disease models.
Volume: 10
Issue: 1
Pages: 14057
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Publication
24105466 | J:205992
First Author: McFarland KN
Year: 2014
Journal: Hum Mol Genet
Title: MeCP2: a novel Huntingtin interactor.
Volume: 23
Issue: 4
Pages: 1036-44
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Publication
24960609 | J:213778
First Author: Tourette C
Year: 2014
Journal: PLoS Biol
Title: The Wnt receptor Ryk reduces neuronal and cell survival capacity by repressing FOXO activity during the early phases of mutant huntingtin pathogenicity.
Volume: 12
Issue: 6
Pages: e1001895
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Publication
27199664 | J:244546
 
First Author: Agostoni E
Year: 2016
Journal: Front Cell Neurosci
Title: Effects of Pin1 Loss in Hdh(Q111) Knock-in Mice.
Volume: 10
Pages: 110
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Publication
15749339 | J:96770
First Author: Tallaksen-Greene SJ
Year: 2005
Journal: Neuroscience
Title: Neuronal intranuclear inclusions and neuropil aggregates in HdhCAG(150) knockin mice.
Volume: 131
Issue: 4
Pages: 843-52
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Publication
22492998 | J:185283
First Author: Tang B
Year: 2012
Journal: Hum Mol Genet
Title: Forkhead box protein p1 is a transcriptional repressor of immune signaling in the CNS: implications for transcriptional dysregulation in Huntington disease.
Volume: 21
Issue: 14
Pages: 3097-111
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Publication
24347167 | J:209517
First Author: Parsons MP
Year: 2014
Journal: J Biol Chem
Title: Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin.
Volume: 289
Issue: 6
Pages: 3518-28
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Publication
23145961 | J:192458
First Author: Soldati C
Year: 2013
Journal: J Neurochem
Title: Dysregulation of REST-regulated coding and non-coding RNAs in a cellular model of Huntington's disease.
Volume: 124
Issue: 3
Pages: 418-30
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Publication
25461618 | J:231417
 
First Author: Yao J
Year: 2014
Journal: Mol Cell Neurosci
Title: Huntingtin is associated with cytomatrix proteins at the presynaptic terminal.
Volume: 63
Pages: 96-100
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Publication
26048156 | J:227439
 
First Author: Swarnkar S
Year: 2015
Journal: Neurobiol Dis
Title: Ectopic expression of the striatal-enriched GTPase Rhes elicits cerebellar degeneration and an ataxia phenotype in Huntington's disease.
Volume: 82
Pages: 66-77
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Publication
32681824 | J:301372
First Author: Lee H
Year: 2020
Journal: Neuron
Title: Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation.
Volume: 107
Issue: 5
Pages: 891-908.e8
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Publication
34469738 | J:324645
First Author: Goold R
Year: 2021
Journal: Cell Rep
Title: FAN1 controls mismatch repair complex assembly via MLH1 retention to stabilize CAG repeat expansion in Huntington's disease.
Volume: 36
Issue: 9
Pages: 109649
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Publication
19525941 | J:152570
First Author: Morfini GA
Year: 2009
Journal: Nat Neurosci
Title: Pathogenic huntingtin inhibits fast axonal transport by activating JNK3 and phosphorylating kinesin.
Volume: 12
Issue: 7
Pages: 864-71
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Publication
25446099 | J:220288
First Author: Choudhury KR
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Chaperone protein HYPK interacts with the first 17 amino acid region of Huntingtin and modulates mutant HTT-mediated aggregation and cytotoxicity.
Volume: 456
Issue: 1
Pages: 66-73
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Publication
18838463 | J:143295
First Author: Dietrich P
Year: 2009
Journal: Hum Mol Genet
Title: Congenital hydrocephalus associated with abnormal subcommissural organ in mice lacking huntingtin in Wnt1 cell lineages.
Volume: 18
Issue: 1
Pages: 142-50
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Publication
32242231 | J:288628
First Author: Jiang M
Year: 2020
Journal: Hum Mol Genet
Title: Nemo-like kinase reduces mutant huntingtin levels and mitigates Huntington's disease.
Volume: 29
Issue: 8
Pages: 1340-1352
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Publication
32681165 | J:295993
First Author: Gerson JE
Year: 2020
Journal: Hum Mol Genet
Title: Ubiquilin-2 differentially regulates polyglutamine disease proteins.
Volume: 29
Issue: 15
Pages: 2596-2610
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Publication
17548833 | J:248257
First Author: Caviston JP
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Huntingtin facilitates dynein/dynactin-mediated vesicle transport.
Volume: 104
Issue: 24
Pages: 10045-50
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Publication
19646509 | J:154511
First Author: Cho KJ
Year: 2009
Journal: Neuroscience
Title: Inhibition of apoptosis signal-regulating kinase 1 reduces endoplasmic reticulum stress and nuclear huntingtin fragments in a mouse model of Huntington disease.
Volume: 163
Issue: 4
Pages: 1128-34
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Publication
21315254 | J:174750
First Author: Crook ZR
Year: 2011
Journal: Neuron
Title: Huntington's disease: can mice lead the way to treatment?
Volume: 69
Issue: 3
Pages: 423-35
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Publication
27516062 | J:259936
 
First Author: Pan Y
Year: 2016
Journal: Sci Rep
Title: Inhibition of DNA Methyltransferases Blocks Mutant Huntingtin-Induced Neurotoxicity.
Volume: 6
Pages: 31022
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Publication
28396396 | J:242134
First Author: Zhao Z
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Formation of neurodegenerative aggresome and death-inducing signaling complex in maternal diabetes-induced neural tube defects.
Volume: 114
Issue: 17
Pages: 4489-4494
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Publication
29212017 | J:254849
First Author: Hachigian LJ
Year: 2017
Journal: Cell Rep
Title: Control of Huntington's Disease-Associated Phenotypes by the Striatum-Enriched Transcription Factor Foxp2.
Volume: 21
Issue: 10
Pages: 2688-2695
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Publication
23209424 | J:194172
First Author: Miller JP
Year: 2012
Journal: PLoS Genet
Title: A genome-scale RNA-interference screen identifies RRAS signaling as a pathologic feature of Huntington's disease.
Volume: 8
Issue: 11
Pages: e1003042
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Publication
36914640 | J:338909
First Author: Pancani T
Year: 2023
Journal: Nat Commun
Title: Cholinergic deficits selectively boost cortical intratelencephalic control of striatum in male Huntington's disease model mice.
Volume: 14
Issue: 1
Pages: 1398
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Publication
21985783 | J:178446
First Author: Keryer G
Year: 2011
Journal: J Clin Invest
Title: Ciliogenesis is regulated by a huntingtin-HAP1-PCM1 pathway and is altered in Huntington disease.
Volume: 121
Issue: 11
Pages: 4372-82
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Publication
31875875 | J:289016
First Author: Di Pardo A
Year: 2020
Journal: Hum Mol Genet
Title: Mutant huntingtin interacts with the sterol regulatory element-binding proteins and impairs their nuclear import.
Volume: 29
Issue: 3
Pages: 418-431
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Publication
14981075 | J:219104
First Author: Gafni J
Year: 2004
Journal: J Biol Chem
Title: Inhibition of calpain cleavage of huntingtin reduces toxicity: accumulation of calpain/caspase fragments in the nucleus.
Volume: 279
Issue: 19
Pages: 20211-20
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Publication
28550168 | J:243191
First Author: Louis Sam Titus ASC
Year: 2017
Journal: J Neurosci
Title: Reduced Expression of Foxp1 as a Contributing Factor in Huntington's Disease.
Volume: 37
Issue: 27
Pages: 6575-6587
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Publication
32859226 | J:302806
First Author: de Souza JM
Year: 2020
Journal: Mol Brain
Title: mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington's disease.
Volume: 13
Issue: 1
Pages: 118
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Publication
33086039 | J:300547
First Author: Yu X
Year: 2020
Journal: Neuron
Title: Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable.
Volume: 108
Issue: 6
Pages: 1146-1162.e10
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Publication
32876667 | J:298297
First Author: Loupe JM
Year: 2020
Journal: Hum Mol Genet
Title: Promotion of somatic CAG repeat expansion by Fan1 knock-out in Huntington's disease knock-in mice is blocked by Mlh1 knock-out.
Volume: 29
Issue: 18
Pages: 3044-3053
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Publication
25478910 | J:218852
First Author: Sanders SS
Year: 2015
Journal: Dev Biol
Title: Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development.
Volume: 397
Issue: 2
Pages: 257-66
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Publication
24991961 | J:224118
First Author: Plotkin JL
Year: 2014
Journal: Neuron
Title: Impaired TrkB receptor signaling underlies corticostriatal dysfunction in Huntington's disease.
Volume: 83
Issue: 1
Pages: 178-88
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Publication
11152656 | J:67077
First Author: Näf D
Year: 2001
Journal: Hum Mol Genet
Title: Mouse models for the Wolf-Hirschhorn deletion syndrome.
Volume: 10
Issue: 2
Pages: 91-8
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Publication
27721240 | J:239619
First Author: Rué L
Year: 2016
Journal: J Clin Invest
Title: Targeting CAG repeat RNAs reduces Huntington's disease phenotype independently of huntingtin levels.
Volume: 126
Issue: 11
Pages: 4319-4330
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Publication
17500595 | J:121567
First Author: Kaltenbach LS
Year: 2007
Journal: PLoS Genet
Title: Huntingtin interacting proteins are genetic modifiers of neurodegeneration.
Volume: 3
Issue: 5
Pages: e82
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Protein Coding Gene
MGP_CAROLIEiJ_G0027139 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029471 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029438 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029387 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029448 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029170 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_96067 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029902 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028579 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029138 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029286 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029245 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029371 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029935 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028304 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028660 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016923 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028135 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8162057 | J:16635
First Author: Lin B
Year: 1994
Journal: Hum Mol Genet
Title: Sequence of the murine Huntington disease gene: evidence for conservation, alternate splicing and polymorphism in a triplet (CCG) repeat [corrected].
Volume: 3
Issue: 1
Pages: 85-92
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Publication
8009370 | J:18404
First Author: Barnes GT
Year: 1994
Journal: Somat Cell Mol Genet
Title: Mouse Huntington's disease gene homolog (Hdh).
Volume: 20
Issue: 2
Pages: 87-97
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Publication
7647777 | J:24940
First Author: Trottier Y
Year: 1995
Journal: Nat Genet
Title: Cellular localization of the Huntington's disease protein and discrimination of the normal and mutated form.
Volume: 10
Issue: 1
Pages: 104-10
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Publication
7759106 | J:23247
First Author: Lin B
Year: 1995
Journal: Genomics
Title: Structural analysis of the 5' region of mouse and human Huntington disease genes reveals conservation of putative promoter region and di- and trinucleotide polymorphisms.
Volume: 25
Issue: 3
Pages: 707-15
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Publication
20018729 | J:156460
First Author: Bradford J
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Expression of mutant huntingtin in mouse brain astrocytes causes age-dependent neurological symptoms.
Volume: 106
Issue: 52
Pages: 22480-5
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Publication
16237181 | J:102158
First Author: Díaz-Hernández M
Year: 2005
Journal: J Neurosci
Title: Full motor recovery despite striatal neuron loss and formation of irreversible amyloid-like inclusions in a conditional mouse model of Huntington's disease.
Volume: 25
Issue: 42
Pages: 9773-81
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Publication
20383138 | J:159605
First Author: Martinez-Vicente M
Year: 2010
Journal: Nat Neurosci
Title: Cargo recognition failure is responsible for inefficient autophagy in Huntington's disease.
Volume: 13
Issue: 5
Pages: 567-76
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Publication
10778856 | J:61490
First Author: Yamamoto A
Year: 2000
Journal: Cell
Title: Reversal of neuropathology and motor dysfunction in a conditional model of Huntington's disease.
Volume: 101
Issue: 1
Pages: 57-66
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Publication
23374344 | J:193455
First Author: Zala D
Year: 2013
Journal: Cell
Title: Vesicular glycolysis provides on-board energy for fast axonal transport.
Volume: 152
Issue: 3
Pages: 479-91
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Publication
19279257 | J:147069
First Author: Heng MY
Year: 2009
Journal: J Neurosci
Title: In vivo evidence for NMDA receptor-mediated excitotoxicity in a murine genetic model of Huntington disease.
Volume: 29
Issue: 10
Pages: 3200-5
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Publication
28930690 | J:254932
First Author: Merienne N
Year: 2017
Journal: Cell Rep
Title: The Self-Inactivating KamiCas9 System for the Editing of CNS Disease Genes.
Volume: 20
Issue: 12
Pages: 2980-2991
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Publication
31379510 | J:284447
 
First Author: Quirion JG
Year: 2019
Journal: Front Cell Neurosci
Title: The Onset and Progression of Hippocampal Synaptic Plasticity Deficits in the Q175FDN Mouse Model of Huntington Disease.
Volume: 13
Pages: 326
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Publication
11494364 | J:76017
First Author: Ishiguro H
Year: 2001
Journal: J Neurosci Res
Title: Age-dependent and tissue-specific CAG repeat instability occurs in mouse knock-in for a mutant Huntington's disease gene.
Volume: 65
Issue: 4
Pages: 289-97
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Publication
11358447 | J:69982
First Author: Guidetti P
Year: 2001
Journal: Exp Neurol
Title: Early degenerative changes in transgenic mice expressing mutant huntingtin involve dendritic abnormalities but no impairment of mitochondrial energy production.
Volume: 169
Issue: 2
Pages: 340-50
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Publication
16230019 | J:105723
First Author: Graham RK
Year: 2006
Journal: Neurobiol Dis
Title: Levels of mutant huntingtin influence the phenotypic severity of Huntington disease in YAC128 mouse models.
Volume: 21
Issue: 2
Pages: 444-55
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Publication
32144144 | J:288894
 
First Author: Glangetas C
Year: 2020
Journal: eNeuro
Title: Deficit in Motor Skill Consolidation-Dependent Synaptic Plasticity at Motor Cortex to Dorsolateral Striatum Synapses in a Mouse Model of Huntington's Disease.
Volume: 7
Issue: 2
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Publication
28927719 | J:250587
 
First Author: Cao JK
Year: 2018
Journal: Behav Brain Res
Title: Sex-dependent behavioral impairments in the HdhQ350/+ mouse line.
Volume: 337
Pages: 34-45
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Publication
11152661 | J:67074
First Author: Lin CH
Year: 2001
Journal: Hum Mol Genet
Title: Neurological abnormalities in a knock-in mouse model of Huntington's disease.
Volume: 10
Issue: 2
Pages: 137-44
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Publication
15200234 | J:90356
First Author: Dixon KT
Year: 2004
Journal: Gene Expr
Title: Mouse Huntington's disease homolog mRNA levels: variation and allele effects.
Volume: 11
Issue: 5-6
Pages: 221-31
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Publication
33113354 | J:298610
First Author: Friedman A
Year: 2020
Journal: Cell
Title: Striosomes Mediate Value-Based Learning Vulnerable in Age and a Huntington's Disease Model.
Volume: 183
Issue: 4
Pages: 918-934.e49
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Publication
10196373 | J:54551
First Author: Usdin MT
Year: 1999
Journal: Hum Mol Genet
Title: Impaired synaptic plasticity in mice carrying the Huntington's disease mutation.
Volume: 8
Issue: 5
Pages: 839-46
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Publication
10196365 | J:54906
First Author: Shelbourne PF
Year: 1999
Journal: Hum Mol Genet
Title: A Huntington's disease CAG expansion at the murine Hdh locus is unstable and associated with behavioural abnormalities in mice.
Volume: 8
Issue: 5
Pages: 763-74
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Publication
15781041 | J:97469
First Author: Kennedy L
Year: 2005
Journal: Brain Res
Title: Alterations in dopamine and benzodiazepine receptor binding precede overt neuronal pathology in mice modelling early Huntington disease pathogenesis.
Volume: 1039
Issue: 1-2
Pages: 14-21
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Publication
14570710 | J:136414
First Author: Kennedy L
Year: 2003
Journal: Hum Mol Genet
Title: Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis.
Volume: 12
Issue: 24
Pages: 3359-67
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Publication
11030759 | J:65412
First Author: Kennedy L
Year: 2000
Journal: Hum Mol Genet
Title: Dramatic mutation instability in HD mouse striatum: does polyglutamine load contribute to cell-specific vulnerability in Huntington's disease?
Volume: 9
Issue: 17
Pages: 2539-44
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Publication
10932179 | J:118556
First Author: Li H
Year: 2000
Journal: Nat Genet
Title: Amino-terminal fragments of mutant huntingtin show selective accumulation in striatal neurons and synaptic toxicity.
Volume: 25
Issue: 4
Pages: 385-9
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Publication
29324753 | J:257872
First Author: Langfelder P
Year: 2018
Journal: PLoS One
Title: MicroRNA signatures of endogenous Huntingtin CAG repeat expansion in mice.
Volume: 13
Issue: 1
Pages: e0190550
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Publication
17519223 | J:142943
First Author: Kuhn A
Year: 2007
Journal: Hum Mol Genet
Title: Mutant huntingtin's effects on striatal gene expression in mice recapitulate changes observed in human Huntington's disease brain and do not differ with mutant huntingtin length or wild-type huntingtin dosage.
Volume: 16
Issue: 15
Pages: 1845-61
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Publication
11606636 | J:72357
First Author: Li H
Year: 2001
Journal: J Neurosci
Title: Huntingtin aggregate-associated axonal degeneration is an early pathological event in Huntington's disease mice.
Volume: 21
Issue: 21
Pages: 8473-81
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Publication
17291464 | J:118624
 
First Author: Shelbourne P
Year: 2007
Journal: Brain Res
Title: Normal electrical properties of hippocampal neurons modelling early Huntington disease pathogenesis.
Volume: 1139
Pages: 226-34
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Publication
8898202 | J:36689
First Author: Mangiarini L
Year: 1996
Journal: Cell
Title: Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.
Volume: 87
Issue: 3
Pages: 493-506
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Publication
11152662 | J:67073
First Author: Fain JN
Year: 2001
Journal: Hum Mol Genet
Title: Abnormalities in the functioning of adipocytes from R6/2 mice that are transgenic for the Huntington's disease mutation.
Volume: 10
Issue: 2
Pages: 145-52
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Publication
25748626 | J:224159
First Author: Mielcarek M
Year: 2015
Journal: PLoS Genet
Title: HDAC4-myogenin axis as an important marker of HD-related skeletal muscle atrophy.
Volume: 11
Issue: 3
Pages: e1005021
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Publication
11752065 | J:73480
First Author: Bogdanov MB
Year: 2001
Journal: J Neurochem
Title: Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease.
Volume: 79
Issue: 6
Pages: 1246-9
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Publication
24906892 | J:218075
First Author: Marangoni M
Year: 2014
Journal: Neurobiol Aging
Title: Age-related axonal swellings precede other neuropathological hallmarks in a knock-in mouse model of Huntington's disease.
Volume: 35
Issue: 10
Pages: 2382-93
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Publication
11821898 | J:74541
First Author: Karpuj MV
Year: 2002
Journal: Nat Med
Title: Prolonged survival and decreased abnormal movements in transgenic model of Huntington disease, with administration of the transglutaminase inhibitor cystamine.
Volume: 8
Issue: 2
Pages: 143-9
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Publication
28993428 | J:263524
First Author: Alpaugh M
Year: 2017
Journal: EMBO Mol Med
Title: Disease-modifying effects of ganglioside GM1 in Huntington's disease models.
Volume: 9
Issue: 11
Pages: 1537-1557
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Publication
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