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Search results 101 to 159 out of 159 for Gab2

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Type

Details

Score

Publication

- | J:85000

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2003

Title:	MGI Sequence Curation Reference

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Publication

21677750 | J:173534

First Author:	Skarnes WC
Year:	2011
Journal:	Nature
Title:	A conditional knockout resource for the genome-wide study of mouse gene function.
Volume:	474
Issue:	7351
Pages:	337-42

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Publication

38355793 | J:345621

First Author:	Adams DJ
Year:	2024
Journal:	Nature
Title:	Genetic determinants of micronucleus formation in vivo.
Volume:	627
Issue:	8002
Pages:	130-136

•

Publication

- | J:293217

First Author:	GemPharmatech
Year:	2020

Title:	GemPharmatech Website.

•

Publication

- | J:342587

First Author:	AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year:	2011

Title:	Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity

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Publication

- | J:68900

First Author:	The Jackson Laboratory Mouse Radiation Hybrid Database
Year:	2004
Journal:	Database Release
Title:	Mouse T31 Radiation Hybrid Data Load

•

Publication

12466851 | J:80000

First Author:	Okazaki Y
Year:	2002
Journal:	Nature
Title:	Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume:	420
Issue:	6915
Pages:	563-73

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Publication

- | J:164563

First Author:	The Gene Ontology Consortium
Year:	2010

Title:	Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs

•

Publication

21267068 | J:153498

First Author:	Diez-Roux G
Year:	2011
Journal:	PLoS Biol
Title:	A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume:	9
Issue:	1
Pages:	e1000582

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Publication

- | J:157972

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2010
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).

•

Publication

- | J:57747

First Author:	MGI Genome Annotation Group and UniGene Staff
Year:	2015
Journal:	Database Download
Title:	MGI-UniGene Interconnection Effort

•

Publication

- | J:75000

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2002

Title:	Mouse Genome Informatics Computational Sequence to Gene Associations

•

Publication

- | J:161428

First Author:	Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year:	2010

Title:	Annotation inferences using phylogenetic trees

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Publication

- | J:85324

First Author:	Mouse Genome Informatics Group
Year:	2003
Journal:	Database Procedure
Title:	Automatic Encodes (AutoE) Reference

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

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Publication

- | J:144087

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform

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Publication

- | J:53168

First Author:	Bairoch A
Year:	1999
Journal:	Database Release
Title:	SWISS-PROT Annotated protein sequence database

•

Publication

- | J:90438

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and loading genome assembly coordinates from NCBI annotations

•

Publication

- | J:63103

First Author:	Mouse Genome Database and National Center for Biotechnology Information
Year:	2000
Journal:	Database Release
Title:	Entrez Gene Load

•

Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

•

Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

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HT Experiment

E-GEOD-75615 | Distinct GAB2 signaling pathways are essential for myeloid and lymphoid transformation and leukemogenesis by BCR-ABL1

Series Id:	GSE75615
Experiment Type:	RNA-Seq
Study Type:	WT vs. Mutant
Source:	ArrayExpress

•

Publication

19523899 | J:201308

First Author:	Harkiolaki M
Year:	2009
Journal:	Structure
Title:	Distinct binding modes of two epitopes in Gab2 that interact with the SH3C domain of Grb2.
Volume:	17
Issue:	6
Pages:	809-22

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Publication

22858987 | J:193230

First Author:	Wöhrle FU
Year:	2013
Journal:	Leukemia
Title:	Gab2 signaling in chronic myeloid leukemia cells confers resistance to multiple Bcr-Abl inhibitors.
Volume:	27
Issue:	1
Pages:	118-29

•

Publication

21636860 | J:174862

First Author:	Futami M
Year:	2011
Journal:	Blood
Title:	G-CSF receptor activation of the Src kinase Lyn is mediated by Gab2 recruitment of the Shp2 phosphatase.
Volume:	118
Issue:	4
Pages:	1077-86

•

Publication

19845770 | J:158321

First Author:	Taguchi Y
Year:	2009
Journal:	Genes Cells
Title:	A unique domain in RANK is required for Gab2 and PLCgamma2 binding to establish osteoclastogenic signals.
Volume:	14
Issue:	11
Pages:	1331-45

•

Publication

10704825 | J:230396

First Author:	Bone H
Year:	2000
Journal:	Cell Signal
Title:	Shc associates with the IL-3 receptor beta subunit, SHIP and Gab2 following IL-3 stimulation. Contribution of Shc PTB and SH2 domains.
Volume:	12
Issue:	3
Pages:	183-94

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Interaction Experiment

Liu Y (2001)

Description:

Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase.

•

Publication

19172738 | -

First Author:	Brummer T
Year:	2008
Journal:	EMBO J
Title:	Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein.
Volume:	27
Issue:	17
Pages:	2305-16

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Publication

16009726 | -

First Author:	Mao Y
Year:	2005
Journal:	J Cell Biol
Title:	A novel role for Gab2 in bFGF-mediated cell survival during retinoic acid-induced neuronal differentiation.
Volume:	170
Issue:	2
Pages:	305-16

•

Publication

11287610 | -

First Author:	Liu Y
Year:	2001
Journal:	Mol Cell Biol
Title:	Scaffolding protein Gab2 mediates differentiation signaling downstream of Fms receptor tyrosine kinase.
Volume:	21
Issue:	9
Pages:	3047-56

•

Allele

Gab2<tm5.1Thir> | MGI:6477303

Name:	growth factor receptor bound protein 2-associated protein 2; targeted mutation 5.1, Toshio Hirano
Allele Type:	Targeted

•

Publication

11572860 | -

First Author:	Yamasaki S
Year:	2001
Journal:	J Biol Chem
Title:	Docking protein Gab2 is phosphorylated by ZAP-70 and negatively regulates T cell receptor signaling by recruitment of inhibitory molecules.
Volume:	276
Issue:	48
Pages:	45175-83

•

Strain

MGI:6146712 | B6;129-Gab2<tm5.1Thir>/Rbrc

Attribute String:

mutant strain, targeted mutation

•

Allele

Tg(CD2-Ptpn11*C459S)1Axdr | MGI:5310938

Name:	transgene insertion 1, Denis R Alexander
Allele Type:	Transgenic
Attribute String:	Dominant negative, Inserted expressed sequence

•

Publication

19735729 | -

First Author:	Ahmed Z
Year:	2010
Journal:	Cell Signal
Title:	Direct binding of Grb2 SH3 domain to FGFR2 regulates SHP2 function.
Volume:	22
Issue:	1
Pages:	23-33

•

Protein Domain

IPR035643 | GRB2_C_SH3

Type:

Domain

Description:

GRB2 (growth factor receptor-bound protein 2) is a critical signaling molecule that regulates the Ras pathway by linking tyrosine kinases to the Ras guanine nucleotide releasing protein Sos (son of sevenless), which converts Ras to the active GTP-bound state. It is ubiquitously expressed in all tissues throughout development and is important in cell cycle progression, motility, morphogenesis and angiogenesis []. In lymphocytes, GRB2 is associated with antigen receptor signaling components []. GRB2 contains an N-terminal SH3 domain, a central SH2 domain and a C-terminal SH3 domain. This entry represents the SH3 domain found at the C terminus of GRB2. This SH3 domain has been found to bind to Gab2 (Grb2-associated binder 2) through epitopes containing RxxK motifs, as well as to the proline-rich C terminus of FGRF2 [, ].

•

Publication

19909362 | -

First Author:	Jang IK
Year:	2009
Journal:	Immunol Rev
Title:	Grb2, a simple adapter with complex roles in lymphocyte development, function, and signaling.
Volume:	232
Issue:	1
Pages:	150-9

•

Publication

18620523 | -

First Author:	Giubellino A
Year:	2008
Journal:	Expert Opin Ther Targets
Title:	Grb2 signaling in cell motility and cancer.
Volume:	12
Issue:	8
Pages:	1021-33

•

Publication

16272304 | J:119396

First Author:	Salmond RJ
Year:	2005
Journal:	J Immunol
Title:	The src homology 2 domain-containing tyrosine phosphatase 2 regulates primary T-dependent immune responses and Th cell differentiation.
Volume:	175
Issue:	10
Pages:	6498-508

•

Strain

MGI:5310966 | B10.Cg-H2<k2> Tg(CD2-Ptpn11*C459S)1Axdr/AxdrH

Attribute String:

congenic, mutant strain, transgenic, major histocompatibility congenic

•

Publication

18725415 | J:142551

First Author:	Samayawardhena LA
Year:	2008
Journal:	J Biol Chem
Title:	Protein-tyrosine phosphatase alpha regulates stem cell factor-dependent c-Kit activation and migration of mast cells.
Volume:	283
Issue:	43
Pages:	29175-85

•

Publication

11805142 | J:76219

First Author:	Takaki S
Year:	2002
Journal:	J Exp Med
Title:	Enhanced hematopoiesis by hematopoietic progenitor cells lacking intracellular adaptor protein, Lnk.
Volume:	195
Issue:	2
Pages:	151-60

•

Publication

16731527 | J:116450

First Author:	Udell CM
Year:	2006
Journal:	J Biol Chem
Title:	Fer and Fps/Fes participate in a Lyn-dependent pathway from FcepsilonRI to platelet-endothelial cell adhesion molecule 1 to limit mast cell activation.
Volume:	281
Issue:	30
Pages:	20949-57

•

Publication

19508371 | J:155066

First Author:	Akimoto M
Year:	2009
Journal:	Scand J Immunol
Title:	Protein tyrosine phosphatase epsilon is a negative regulator of FcepsilonRI-mediated mast cell responses.
Volume:	69
Issue:	5
Pages:	401-11

•

Publication

11739737 | J:78670

First Author:	Wolf I
Year:	2002
Journal:	Mol Cell Biol
Title:	Gab3, a new DOS/Gab family member, facilitates macrophage differentiation.
Volume:	22
Issue:	1
Pages:	231-44

•

Publication

12640125 | J:82505

First Author:	Seiffert M
Year:	2003
Journal:	Mol Cell Biol
Title:	Gab3-deficient mice exhibit normal development and hematopoiesis and are immunocompetent.
Volume:	23
Issue:	7
Pages:	2415-24

•

Publication

17513616 | J:147024

First Author:	Hong H
Year:	2007
Journal:	Blood
Title:	The Src family kinase Hck regulates mast cell activation by suppressing an inhibitory Src family kinase Lyn.
Volume:	110
Issue:	7
Pages:	2511-9

•

Publication

22859831 | J:191113

First Author:	Serra-Pages M
Year:	2012
Journal:	J Leukoc Biol
Title:	E-prostanoid 2 receptors dampen mast cell degranulation via cAMP/PKA-mediated suppression of IgE-dependent signaling.
Volume:	92
Issue:	6
Pages:	1155-65

•

Publication

28804122 | J:253876

First Author:	Gu S
Year:	2018
Journal:	Leukemia
Title:	SHP2 is required for BCR-ABL1-induced hematologic neoplasia.
Volume:	32
Issue:	1
Pages:	203-213

•

Publication

17579026 | J:149424

First Author:	Leung WH
Year:	2007
Journal:	J Immunol
Title:	The inositol 5'-phosphatase SHIP-2 negatively regulates IgE-induced mast cell degranulation and cytokine production.
Volume:	179
Issue:	1
Pages:	95-102

•

Publication

37161070 | J:337733

First Author:	Langhammer M
Year:	2023
Journal:	Leukemia
Title:	Mast cell deficiency prevents BCR::ABL1 induced splenomegaly and cytokine elevation in a CML mouse model.
Volume:	37
Issue:	7
Pages:	1474-1484

•

Publication

27861634 | J:251516

First Author:	Yasui T
Year:	2016
Journal:	PLoS One
Title:	Molecular Characterization of Striated Muscle-Specific Gab1 Isoform as a Critical Signal Transducer for Neuregulin-1/ErbB Signaling in Cardiomyocytes.
Volume:	11
Issue:	11
Pages:	e0166710

•

Publication

7665895 | J:105228

First Author:	Zhumabekov T
Year:	1995
Journal:	J Immunol Methods
Title:	Improved version of a human CD2 minigene based vector for T cell-specific expression in transgenic mice.
Volume:	185
Issue:	1
Pages:	133-40

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Protein

Q60631

Organism:	Mus musculus/domesticus
Length:	217
Fragment?:	false

•

Protein

Q3U1Q4

Organism:	Mus musculus/domesticus
Length:	217
Fragment?:	false

•

Protein

Q3U5I5

Organism:	Mus musculus/domesticus
Length:	217
Fragment?:	false

•

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