Type |
Details |
Score |
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Allele |
Name: |
interferon induced with helicase C domain 1; endonuclease-mediated mutation 2, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Allele |
Name: |
interferon induced with helicase C domain 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
261
|
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2016 |
Journal: |
EMBO Rep |
Title: |
RNF123 has an E3 ligase-independent function in RIG-I-like receptor-mediated antiviral signaling. |
Volume: |
17 |
Issue: |
8 |
Pages: |
1155-68 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of RING finger-containing proteins, including RNF123/RSPRY1 from humans and RKP from Arabidopsis.RNF123 is the catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. It also functions as an inhibitor of innate antiviral signalling mediated by DDX58 and IFIH1 independently of its E3 ligase activity []. The role of RSPRY1 (RING finger and SPRY domain-containing protein 1) is not known, but it may have a role in bone development. Mutations in RSPRY1 cause skeletal dysplasia [].RKP is an E3 ubiquitin-protein ligase that promotes the ubiquitination and proteasomal degradation of KRP1 and KRP2 [, ]. |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Faden M |
Year: |
2015 |
Journal: |
Am J Hum Genet |
Title: |
Identification of a Recognizable Progressive Skeletal Dysplasia Caused by RSPRY1 Mutations. |
Volume: |
97 |
Issue: |
4 |
Pages: |
608-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lai J |
Year: |
2009 |
Journal: |
Plant J |
Title: |
RKP, a RING finger E3 ligase induced by BSCTV C4 protein, affects geminivirus infection by regulation of the plant cell cycle. |
Volume: |
57 |
Issue: |
5 |
Pages: |
905-17 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ren H |
Year: |
2008 |
Journal: |
Plant J |
Title: |
Degradation of the cyclin-dependent kinase inhibitor KRP1 is regulated by two different ubiquitin E3 ligases. |
Volume: |
53 |
Issue: |
5 |
Pages: |
705-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sheikh F |
Year: |
2014 |
Journal: |
J Leukoc Biol |
Title: |
An essential role for IFN-β in the induction of IFN-stimulated gene expression by LPS in macrophages. |
Volume: |
96 |
Issue: |
4 |
Pages: |
591-600 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishikawa A |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Identification of a Putative Quantitative Trait Gene for Resistance to Obesity in Mice Using Transcriptome Analysis and Causal Inference Tests. |
Volume: |
12 |
Issue: |
1 |
Pages: |
e0170652 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang A |
Year: |
2023 |
Journal: |
Int Immunopharmacol |
Title: |
IFIH1/IRF1/STAT1 promotes sepsis associated inflammatory lung injury via activating macrophage M1 polarization. |
Volume: |
114 |
|
Pages: |
109478 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1239
|
Fragment?: |
true |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1314
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
576
|
Fragment?: |
false |
|
•
•
•
•
•
|