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Search results 1 to 100 out of 318 for Furin

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Type Details Score
Publication
2266110 | J:23406
First Author: Hatsuzawa K
Year: 1990
Journal: J Biol Chem
Title: Structure and expression of mouse furin, a yeast Kex2-related protease. Lack of processing of coexpressed prorenin in GH4C1 cells.
Volume: 265
Issue: 36
Pages: 22075-8
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Publication
9412467 | J:51716
First Author: Liu G
Year: 1997
Journal: J Cell Biol
Title: Cytoskeletal protein ABP-280 directs the intracellular trafficking of furin and modulates proprotein processing in the endocytic pathway.
Volume: 139
Issue: 7
Pages: 1719-33
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Publication
18713856 | J:138967
First Author: Louagie E
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Role of furin in granular acidification in the endocrine pancreas: identification of the V-ATPase subunit Ac45 as a candidate substrate.
Volume: 105
Issue: 34
Pages: 12319-24
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Publication
12794637 | -
First Author: Henrich S
Year: 2003
Journal: Nat Struct Biol
Title: The crystal structure of the proprotein processing proteinase furin explains its stringent specificity.
Volume: 10
Issue: 7
Pages: 520-6
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Publication
9231654 | J:41797
First Author: Kayo T
Year: 1997
Journal: Diabetes
Title: Proprotein-processing endoprotease furin controls growth of pancreatic beta-cells.
Volume: 46
Issue: 8
Pages: 1296-304
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Publication
15471862 | J:118515
First Author: Roebroek AJ
Year: 2004
Journal: J Biol Chem
Title: Limited redundancy of the proprotein convertase furin in mouse liver.
Volume: 279
Issue: 51
Pages: 53442-50
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Publication
25926688 | J:242670
First Author: Ortutay Z
Year: 2015
Journal: J Leukoc Biol
Title: Proprotein convertase FURIN regulates T cell receptor-induced transactivation.
Volume: 98
Issue: 1
Pages: 73-83
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Publication
21147780 | J:169483
First Author: Essalmani R
Year: 2011
Journal: J Biol Chem
Title: In vivo evidence that furin from hepatocytes inactivates PCSK9.
Volume: 286
Issue: 6
Pages: 4257-63
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Publication
28972540 | J:252592
First Author: Al Rifai O
Year: 2017
Journal: J Clin Invest
Title: Proprotein convertase furin regulates osteocalcin and bone endocrine function.
Volume: 127
Issue: 11
Pages: 4104-4117
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Publication
12360192 | J:79598
First Author: Thomas G
Year: 2002
Journal: Nat Rev Mol Cell Biol
Title: Furin at the cutting edge: from protein traffic to embryogenesis and disease.
Volume: 3
Issue: 10
Pages: 753-66
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Publication
18701887 | J:138986
First Author: Pesu M
Year: 2008
Journal: Nature
Title: T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance.
Volume: 455
Issue: 7210
Pages: 246-50
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Publication
18772886 | J:141156
First Author: Blanchet MH
Year: 2008
Journal: EMBO J
Title: Cripto recruits Furin and PACE4 and controls Nodal trafficking during proteolytic maturation.
Volume: 27
Issue: 19
Pages: 2580-91
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Publication
8422932 | J:3714
First Author: Torii S
Year: 1993
Journal: FEBS Lett
Title: Localization of Kex2-like processing endoproteases, furin and PC4, within mouse testis by in situ hybridization.
Volume: 316
Issue: 1
Pages: 12-6
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Publication
36274943 | J:330951
First Author: Liang Z
Year: 2022
Journal: iScience
Title: The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance.
Volume: 25
Issue: 10
Pages: 105233
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Publication
1354647 | J:1676
First Author: Copeland NG
Year: 1992
Journal: Genomics
Title: Regional localization of three convertases, PC1 (Nec-1), PC2 (Nec-2), and furin (Fur), on mouse chromosomes.
Volume: 13
Issue: 4
Pages: 1356-8
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Publication
22733989 | J:196532
First Author: Kim W
Year: 2012
Journal: Mol Cell Biol
Title: Loss of endothelial furin leads to cardiac malformation and early postnatal death.
Volume: 32
Issue: 17
Pages: 3382-91
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Publication
26167473 | J:317010
 
First Author: Declercq J
Year: 2015
Journal: Biomed Res Int
Title: Liver-Specific Inactivation of the Proprotein Convertase FURIN Leads to Increased Hepatocellular Carcinoma Growth.
Volume: 2015
Pages: 148651
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Publication
8631882 | J:32910
First Author: Kayo T
Year: 1996
Journal: J Biol Chem
Title: Proprotein-processing endoprotease furin decreases regulated secretory pathway-specific proteins in the pancreatic beta cell line MIN6.
Volume: 271
Issue: 18
Pages: 10731-7
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Publication
9199665 | J:40644
First Author: Farhadi H
Year: 1997
Journal: J Histochem Cytochem
Title: Prohormone convertases in mouse submandibular gland: co-localization of furin and nerve growth factor.
Volume: 45
Issue: 6
Pages: 795-804
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Publication
28569793 | J:272231
First Author: Meng TG
Year: 2017
Journal: Cell Death Dis
Title: Oocyte-specific deletion of furin leads to female infertility by causing early secondary follicle arrest in mice.
Volume: 8
Issue: 6
Pages: e2846
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Publication
17283058 | J:121404
First Author: Tellier E
Year: 2007
Journal: Mol Cell Biol
Title: Role for furin in tumor necrosis factor alpha-induced activation of the matrix metalloproteinase/sphingolipid mitogenic pathway.
Volume: 27
Issue: 8
Pages: 2997-3007
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Publication
8891276 | J:35361
First Author: Meyer A
Year: 1996
Journal: Brain Res
Title: Kainic acid increases the expression of the prohormone convertases furin and PC1 in the mouse hippocampus.
Volume: 732
Issue: 1-2
Pages: 121-32
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Publication
14684599 | J:88698
First Author: Dey A
Year: 2004
Journal: Endocrinology
Title: Furin and prohormone convertase 1/3 are major convertases in the processing of mouse pro-growth hormone-releasing hormone.
Volume: 145
Issue: 4
Pages: 1961-71
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26416966 | J:227651
First Author: Bessonnard S
Year: 2015
Journal: J Cell Biol
Title: PC7 and the related proteases Furin and Pace4 regulate E-cadherin function during blastocyst formation.
Volume: 210
Issue: 7
Pages: 1185-97
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Publication
21896659 | J:176435
First Author: Mesnard D
Year: 2011
Journal: Genes Dev
Title: The microenvironment patterns the pluripotent mouse epiblast through paracrine Furin and Pace4 proteolytic activities.
Volume: 25
Issue: 17
Pages: 1871-80
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Publication
36374777 | J:331452
 
First Author: Coppola I
Year: 2022
Journal: Mol Metab
Title: Loss of hypothalamic Furin affects POMC to proACTH cleavage and feeding behavior in high-fat diet-fed mice.
Volume: 66
Pages: 101627
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Publication
32389711 | J:289151
 
First Author: He Z
Year: 2020
Journal: Cancer Lett
Title: Loss of the proprotein convertase Furin in T cells represses mammary tumorigenesis in oncogene-driven triple negative breast cancer.
Volume: 484
Pages: 40-49
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Publication
23918928 | J:203527
First Author: Essalmani R
Year: 2013
Journal: J Biol Chem
Title: Furin is the primary in vivo convertase of angiopoietin-like 3 and endothelial lipase in hepatocytes.
Volume: 288
Issue: 37
Pages: 26410-8
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Publication
30651003 | J:291374
First Author: Yakala GK
Year: 2019
Journal: Arterioscler Thromb Vasc Biol
Title: FURIN Inhibition Reduces Vascular Remodeling and Atherosclerotic Lesion Progression in Mice.
Volume: 39
Issue: 3
Pages: 387-401
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Publication
30266770 | J:267979
First Author: Li Y
Year: 2018
Journal: J Immunol
Title: STAT6 and Furin Are Successive Triggers for the Production of TGF-β by T Cells.
Volume: 201
Issue: 9
Pages: 2612-2623
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Publication
1765368 | J:419
First Author: Seidah NG
Year: 1991
Journal: Genomics
Title: Chromosomal assignments of the genes for neuroendocrine convertase PC1 (NEC1) to human 5q15-21, neuroendocrine convertase PC2 (NEC2) to human 20p11.1-11.2, and furin (mouse 7[D1-E2] region).
Volume: 11
Issue: 1
Pages: 103-7
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10701998 | J:59052
First Author: Seidah NG
Year: 1999
Journal: Brain Res
Title: Proprotein and prohormone convertases: a family of subtilases generating diverse bioactive polypeptides.
Volume: 848
Issue: 1-2
Pages: 45-62
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Publication
8226974 | J:15843
First Author: Robertson BJ
Year: 1993
Journal: J Biol Chem
Title: Defective processing of the insulin receptor in an endoprotease-deficient Chinese hamster cell strain is corrected by expression of mouse furin.
Volume: 268
Issue: 32
Pages: 24274-7
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8003017 | J:18659
First Author: Goodman LJ
Year: 1994
Journal: Biochem Biophys Res Commun
Title: Autoproteolytic activation of the mouse prohormone convertase mPC1.
Volume: 201
Issue: 2
Pages: 795-804
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15606899 | J:95653
First Author: Wickham L
Year: 2005
Journal: J Neurochem
Title: Beta-amyloid protein converting enzyme 1 and brain-specific type II membrane protein BRI3: binding partners processed by furin.
Volume: 92
Issue: 1
Pages: 93-102
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18425334 | J:142978
First Author: De Vos L
Year: 2008
Journal: Int J Oncol
Title: MMTV-cre-mediated fur inactivation concomitant with PLAG1 proto-oncogene activation delays salivary gland tumorigenesis in mice.
Volume: 32
Issue: 5
Pages: 1073-83
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29723063 | J:282780
First Author: Shi LY
Year: 2018
Journal: FASEB J
Title: Placenta-specific 1 regulates oocyte meiosis and fertilization through furin.
Volume: 32
Issue: 10
Pages: 5483-5494
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23441131 | J:316434
First Author: Fu J
Year: 2013
Journal: Neoplasia
Title: Enhanced UV-induced skin carcinogenesis in transgenic mice overexpressing proprotein convertases.
Volume: 15
Issue: 2
Pages: 169-79
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Publication
34149625 | J:308473
 
First Author: Al Rifai O
Year: 2021
Journal: Front Endocrinol (Lausanne)
Title: In Vivo Analysis of the Contribution of Proprotein Convertases to the Processing of FGF23.
Volume: 12
Pages: 690681
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Publication
15505202 | J:93446
First Author: Guzman-Ayala M
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Nodal protein processing and fibroblast growth factor 4 synergize to maintain a trophoblast stem cell microenvironment.
Volume: 101
Issue: 44
Pages: 15656-60
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Publication
24101515 | J:201970
First Author: Wetsel WC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Disruption of the expression of the proprotein convertase PC7 reduces BDNF production and affects learning and memory in mice.
Volume: 110
Issue: 43
Pages: 17362-7
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19056739 | J:147603
First Author: Ikonomov OC
Year: 2009
Journal: J Biol Chem
Title: Kinesin adapter JLP links PIKfyve to microtubule-based endosome-to-trans-Golgi network traffic of furin.
Volume: 284
Issue: 6
Pages: 3750-61
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Publication
28468828 | J:245609
First Author: Essalmani R
Year: 2017
Journal: J Biol Chem
Title: Thrombin activation of protein C requires prior processing by a liver proprotein convertase.
Volume: 292
Issue: 25
Pages: 10564-10573
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Publication
30840660 | J:273415
First Author: Dupays L
Year: 2019
Journal: PLoS One
Title: Furin, a transcriptional target of NKX2-5, has an essential role in heart development and function.
Volume: 14
Issue: 3
Pages: e0212992
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20876279 | J:165252
First Author: Mesnard D
Year: 2010
Journal: J Cell Biol
Title: Imaging proprotein convertase activities and their regulation in the implanting mouse blastocyst.
Volume: 191
Issue: 1
Pages: 129-39
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Publication
16950123 | J:112799
First Author: Ben-Haim N
Year: 2006
Journal: Dev Cell
Title: The nodal precursor acting via activin receptors induces mesoderm by maintaining a source of its convertases and BMP4.
Volume: 11
Issue: 3
Pages: 313-23
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10603343 | J:56972
First Author: Constam DB
Year: 2000
Journal: Development
Title: Tissue-specific requirements for the proprotein convertase furin/SPC1 during embryonic turning and heart looping.
Volume: 127
Issue: 2
Pages: 245-54
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Publication
18664504 | J:140467
First Author: Scamuffa N
Year: 2008
Journal: Gut
Title: Regulation of prohepcidin processing and activity by the subtilisin-like proprotein convertases Furin, PC5, PACE4 and PC7.
Volume: 57
Issue: 11
Pages: 1573-82
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15082773 | J:90197
First Author: Marschang P
Year: 2004
Journal: Mol Cell Biol
Title: Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.
Volume: 24
Issue: 9
Pages: 3782-93
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9811571 | J:50582
First Author: Roebroek AJ
Year: 1998
Journal: Development
Title: Failure of ventral closure and axial rotation in embryos lacking the proprotein convertase Furin.
Volume: 125
Issue: 24
Pages: 4863-76
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7819324 | J:23191
First Author: Seidah NG
Year: 1994
Journal: Biochimie
Title: The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions.
Volume: 76
Issue: 3-4
Pages: 197-209
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12447384 | J:81247
First Author: Beck S
Year: 2002
Journal: Nat Cell Biol
Title: Extraembryonic proteases regulate Nodal signalling during gastrulation.
Volume: 4
Issue: 12
Pages: 981-5
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16728477 | J:289378
First Author: Mesnard D
Year: 2006
Journal: Development
Title: Nodal specifies embryonic visceral endoderm and sustains pluripotent cells in the epiblast before overt axial patterning.
Volume: 133
Issue: 13
Pages: 2497-505
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17936261 | J:127541
First Author: Andersson O
Year: 2007
Journal: Dev Biol
Title: Distinct and cooperative roles of mammalian Vg1 homologs GDF1 and GDF3 during early embryonic development.
Volume: 311
Issue: 2
Pages: 500-11
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19752221 | J:152772
First Author: Medina F
Year: 2009
Journal: J Immunol
Title: Furin-processed antigens targeted to the secretory route elicit functional TAP1-/-CD8+ T lymphocytes in vivo.
Volume: 183
Issue: 7
Pages: 4639-47
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8661011 | J:32889
First Author: Chu FF
Year: 1996
Journal: Genomics
Title: The mouse glutathione peroxidase Gpx2 gene maps to chromosome 12; its pseudogene Gpx2-ps maps to chromosome 7.
Volume: 33
Issue: 3
Pages: 516-8
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33284103 | J:317447
   
First Author: Al Rifai O
Year: 2020
Journal: Elife
Title: The half-life of the bone-derived hormone osteocalcin is regulated through O-glycosylation in mice, but not in humans.
Volume: 9
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8825647 | J:30584
First Author: Mohandas TK
Year: 1995
Journal: Genomics
Title: Localization of the tight junction protein gene TJP1 to human chromosome 15q13, distal to the Prader-Willi/Angelman region, and to mouse chromosome 7.
Volume: 30
Issue: 3
Pages: 594-7
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10852913 | J:63941
First Author: Liu Z
Year: 2000
Journal: J Biol Chem
Title: Characterization of human RhCG and mouse Rhcg as novel nonerythroid Rh glycoprotein homologues predominantly expressed in kidney and testis.
Volume: 275
Issue: 33
Pages: 25641-51
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9452465 | J:45717
First Author: Furuta M
Year: 1998
Journal: J Biol Chem
Title: Incomplete processing of proinsulin to insulin accompanied by elevation of Des-31,32 proinsulin intermediates in islets of mice lacking active PC2.
Volume: 273
Issue: 6
Pages: 3431-7
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1429684 | J:52522
First Author: Steiner DF
Year: 1992
Journal: J Biol Chem
Title: The new enzymology of precursor processing endoproteases.
Volume: 267
Issue: 33
Pages: 23435-8
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16829522 | J:116943
First Author: Thomas JT
Year: 2006
Journal: J Biol Chem
Title: CDMP1/GDF5 has specific processing requirements that restrict its action to joint surfaces.
Volume: 281
Issue: 36
Pages: 26725-33
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9291583 | J:42730
First Author: Rancourt SL
Year: 1997
Journal: Dev Genet
Title: Murine subtilisin-like proteinase SPC6 is expressed during embryonic implantation, somitogenesis, and skeletal formation.
Volume: 21
Issue: 1
Pages: 75-81
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9666083 | J:49056
First Author: Yoshitomi H
Year: 1998
Journal: Gene
Title: Cloning of mouse uncoupling protein 3 cDNA and 5'-flanking region, and its genetic map.
Volume: 215
Issue: 1
Pages: 77-84
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11587854 | J:72333
First Author: Glowacki G
Year: 2001
Journal: Gene
Title: Structure, chromosomal localization, and expression of the gene for mouse ecto-mono(ADP-ribosyl)transferase ART5.
Volume: 275
Issue: 2
Pages: 267-77
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23645881 | J:204761
First Author: Edwards JP
Year: 2013
Journal: J Immunol
Title: Regulation of the expression of GARP/latent TGF-β1 complexes on mouse T cells and their role in regulatory T cell and Th17 differentiation.
Volume: 190
Issue: 11
Pages: 5506-15
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7782070 | J:23897
First Author: Mbikay M
Year: 1995
Journal: Genomics
Title: Chromosomal assignment of the genes for proprotein convertases PC4, PC5, and PACE 4 in mouse and human.
Volume: 26
Issue: 1
Pages: 123-9
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9885250 | J:52417
First Author: Constam DB
Year: 1999
Journal: J Cell Biol
Title: Regulation of bone morphogenetic protein activity by pro domains and proprotein convertases.
Volume: 144
Issue: 1
Pages: 139-49
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17548631 | J:148583
First Author: Tiwari N
Year: 2007
Journal: J Immunol
Title: A transporter associated with antigen-processing independent vacuolar pathway for the MHC class I-mediated presentation of endogenous transmembrane proteins.
Volume: 178
Issue: 12
Pages: 7932-42
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8698813 | J:34068
First Author: Constam DB
Year: 1996
Journal: J Cell Biol
Title: SPC4, SPC6, and the novel protease SPC7 are coexpressed with bone morphogenetic proteins at distinct sites during embryogenesis.
Volume: 134
Issue: 1
Pages: 181-91
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10585447 | J:58784
First Author: Xu S
Year: 1999
Journal: J Biol Chem
Title: PHR1 encodes an abundant, pleckstrin homology domain-containing integral membrane protein in the photoreceptor outer segments.
Volume: 274
Issue: 50
Pages: 35676-85
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16163737 | J:104961
First Author: St Germain C
Year: 2005
Journal: Mol Reprod Dev
Title: Expression and transient nuclear translocation of proprotein convertase 1 (PC1) during mouse preimplantation embryonic development.
Volume: 72
Issue: 4
Pages: 483-93
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15078902 | J:89488
First Author: Seaman MN
Year: 2004
Journal: J Cell Biol
Title: Cargo-selective endosomal sorting for retrieval to the Golgi requires retromer.
Volume: 165
Issue: 1
Pages: 111-22
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21518694 | J:174826
First Author: Rousselet E
Year: 2011
Journal: J Lipid Res
Title: PCSK9 reduces the protein levels of the LDL receptor in mouse brain during development and after ischemic stroke.
Volume: 52
Issue: 7
Pages: 1383-91
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25453830 | J:263215
First Author: Osterwalder M
Year: 2014
Journal: Dev Cell
Title: HAND2 targets define a network of transcriptional regulators that compartmentalize the early limb bud mesenchyme.
Volume: 31
Issue: 3
Pages: 345-357
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20530870 | J:163721
First Author: Yang T
Year: 2010
Journal: J Clin Invest
Title: E-selectin ligand-1 regulates growth plate homeostasis in mice by inhibiting the intracellular processing and secretion of mature TGF-beta.
Volume: 120
Issue: 7
Pages: 2474-85
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21205794 | J:170542
First Author: Weber S
Year: 2011
Journal: Development
Title: The disintegrin/metalloproteinase Adam10 is essential for epidermal integrity and Notch-mediated signaling.
Volume: 138
Issue: 3
Pages: 495-505
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Publication
11110696 | J:61187
First Author: Gwynn B
Year: 2000
Journal: Blood
Title: Defects in the cappuccino (cno) gene on mouse chromosome 5 and human 4p cause Hermansky-Pudlak syndrome by an AP-3-independent mechanism.
Volume: 96
Issue: 13
Pages: 4227-35
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18781635 | J:138922
First Author: Uez N
Year: 2008
Journal: Genesis
Title: Sall4 isoforms act during proximal-distal and anterior-posterior axis formation in the mouse embryo.
Volume: 46
Issue: 9
Pages: 463-77
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15829518 | J:98382
First Author: Donnison M
Year: 2005
Journal: Development
Title: Loss of the extraembryonic ectoderm in Elf5 mutants leads to defects in embryonic patterning.
Volume: 132
Issue: 10
Pages: 2299-308
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Publication
20708584 | J:163670
First Author: Spruce T
Year: 2010
Journal: Dev Cell
Title: An early developmental role for miRNAs in the maintenance of extraembryonic stem cells in the mouse embryo.
Volume: 19
Issue: 2
Pages: 207-19
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Publication
18206867 | J:131988
First Author: Han D
Year: 2008
Journal: Dev Biol
Title: SRG3, a core component of mouse SWI/SNF complex, is essential for extra-embryonic vascular development.
Volume: 315
Issue: 1
Pages: 136-46
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9722956 | J:49394
First Author: Yamazaki K
Year: 1998
Journal: Genomics
Title: Genetic mapping of mouse transient receptor potential (Trrp) genes responsible for capacitative calcium entry channels to chromosomes 3, 7, 9, and X.
Volume: 51
Issue: 2
Pages: 303-5
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Publication
24859004 | J:219394
First Author: Boroviak T
Year: 2014
Journal: Nat Cell Biol
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