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Search results 201 to 214 out of 214 for Duox2

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0.018s
Type Details Score
Protein
Organism: Mus musculus/domesticus
Length: 100  
Fragment?: true
Publication
First Author: Grasberger H
Year: 2006
Journal: J Biol Chem
Title: Identification of the maturation factor for dual oxidase. Evolution of an eukaryotic operon equivalent.
Volume: 281
Issue: 27
Pages: 18269-72
Protein Domain
Type: Family
Description: DuoxA (Dual oxidase maturation factor) is the essential protein necessary for the final release of DUOX2 (an NADPH:O2 oxidoreductase flavoprotein) from the endoplasmic reticulum. Dual oxidases (DUOX1 and DUOX2) constitute the catalytic core of the hydrogen peroxide generator, which generates H2O2 at the apical membrane of thyroid follicular cells, essential for iodination of thyroglobulin by thyroid peroxidases. DuoxA carries five membrane-integral regions including a reverse signal-anchor with external N terminus (type III) and two N-glycosylation sites []. It is conserved from nematodes to humans.
Publication
First Author: Ha EM
Year: 2005
Journal: Science
Title: A direct role for dual oxidase in Drosophila gut immunity.
Volume: 310
Issue: 5749
Pages: 847-50
Publication
First Author: Grasberger H
Year: 2012
Journal: Mol Endocrinol
Title: Mice deficient in dual oxidase maturation factors are severely hypothyroid.
Volume: 26
Issue: 3
Pages: 481-92
Publication
First Author: Cagle L
Year: 2021
Journal: Am J Respir Cell Mol Biol
Title: Role of Dual Oxidases in Ventilator-induced Lung Injury.
Volume: 64
Issue: 2
Pages: 208-215
Publication
First Author: Afink GB
Year: 2010
Journal: Thyroid
Title: Initial characterization of C16orf89, a novel thyroid-specific gene.
Volume: 20
Issue: 7
Pages: 811-21
Publication
First Author: Esworthy RS
Year: 2012
Journal: PLoS One
Title: Analysis of candidate colitis genes in the Gdac1 locus of mice deficient in glutathione peroxidase-1 and -2.
Volume: 7
Issue: 9
Pages: e44262
Publication
First Author: Kim BW
Year: 2012
Journal: Free Radic Biol Med
Title: Expression of lactoperoxidase in differentiated mouse colon epithelial cells.
Volume: 52
Issue: 9
Pages: 1569-76
Publication
First Author: Cha JJ
Year: 2017
Journal: Lab Invest
Title: APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury.
Volume: 97
Issue: 4
Pages: 419-431
Publication
First Author: Grasberger H
Year: 2013
Journal: Gastroenterology
Title: Dual oxidases control release of hydrogen peroxide by the gastric epithelium to prevent Helicobacter felis infection and inflammation in mice.
Volume: 145
Issue: 5
Pages: 1045-54
Publication  
First Author: Cagle LA
Year: 2022
Journal: Front Physiol
Title: Early mechanisms of neutrophil activation and transmigration in acute lung injury.
Volume: 13
Pages: 1059686
Protein
Organism: Mus musculus/domesticus
Length: 1058  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 1551  
Fragment?: false