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Search results 301 to 350 out of 350 for Sp2

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Hits by Strain

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Type Details Score
Strain
Attribute String: gene trap, mutant strain
Allele  
Name: Sp2 transcription factor; gene trap IST14266E10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST13158C2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST10029E2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST14118E2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST14133E1, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST14142E6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST14474C7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST10322G3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST13695H3, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST14143C7, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST15044F10, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST13562F6, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST13887G5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST14404B2, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST14459C5, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Allele  
Name: Sp2 transcription factor; gene trap IST14588E4, Texas A&M Institute for Genomic Medicine
Allele Type: Gene trapped
Genotype
Symbol: Sp2/Sp2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Sp2/Sp2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Sp2/Sp2
Background: involves: 129P2/OlaHsd * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Sp2/Sp2
Background: involves: 129
Zygosity: cn
Has Mutant Allele: true
Protein
Organism: Mus musculus/domesticus
Length: 428  
Fragment?: false
Genotype
Symbol: Sp2/Sp2 Tg(Nes-cre)1Kln/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sp2/Sp2<+> Tg(Nes-cre)1Kln/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Sp2/Sp2 Emx1/Emx1<+>
Background: involves: 129S2/SvPas
Zygosity: cn
Has Mutant Allele: true
Pseudogene
Type: pseudogene
Organism: mouse, laboratory
Publication  
First Author: Martin BM
Year: 1994
Journal: Biochem J
Title: Novel K(+)-channel-blocking toxins from the venom of the scorpion Centruroides limpidus limpidus Karsch.
Volume: 304 ( Pt 1)
Pages: 51-6
Publication
First Author: Zhang N
Year: 2004
Journal: Proteins
Title: Solution structure of BmKK2, a new potassium channel blocker from the venom of chinese scorpion Buthus martensi Karsch.
Volume: 55
Issue: 4
Pages: 835-45
Publication  
First Author: Zhang Y
Year: 2019
Journal: Cell Biosci
Title: Immunosuppressive effects of a novel potassium channel toxin Ktx-Sp2 from Scorpiops Pocoki.
Volume: 9
Pages: 99
Publication
First Author: Reynaud S
Year: 2020
Journal: J Med Chem
Title: A Venomics Approach Coupled to High-Throughput Toxin Production Strategies Identifies the First Venom-Derived Melanocortin Receptor Agonists.
Volume: 63
Issue: 15
Pages: 8250-8264
Publication  
First Author: Zhao F
Year: 2021
Journal: Toxins (Basel)
Title: BmK NSPK, a Potent Potassium Channel Inhibitor from Scorpion Buthus martensii Karsch, Promotes Neurite Outgrowth via NGF/TrkA Signaling Pathway.
Volume: 13
Issue: 1
Protein Domain
Type: Family
Description: Scorpion venoms contain a variety of peptides toxic to mammals, insects and crustaceans. Among these peptides there is a family of short toxins (30 to 40 residues) [, ]. This entry represents members of this family with potassium channel blocking activity []. KTX 12 Sp2 toxin from Scorpiops pococki has shown a strong immunosuppressant effect, being an interesting therapeutic agent for autoimmune disease treatment []. This entry also includes NU-buthitoxin-Ptr1a, a toxin that acts as an agonist on melanocortin receptors and does not show activity on mammalian sodium or potassium channels []. Toxin BmK NSPK from Manchurian scorpion, is a voltage-gated potassium (Kv) channel inhibitor that augments neurite extension via NGF/TrkA signaling pathway. As Kv channels may represent molecular targets to modulate spinal cord neurons development and regeneration, they become interesting targets to develop treatments for spinal cord injury [].
Publication
First Author: Lippens G
Year: 1995
Journal: Biochemistry
Title: NMR sequential assignments and solution structure of chlorotoxin, a small scorpion toxin that blocks chloride channels.
Volume: 34
Issue: 1
Pages: 13-21
Publication
First Author: Chen J
Year: 2009
Journal: J Biol Chem
Title: A new isoform of interleukin-3 receptor {alpha} with novel differentiation activity and high affinity binding mode.
Volume: 284
Issue: 9
Pages: 5763-73
Publication
First Author: Kurosawa Y
Year: 1982
Journal: J Exp Med
Title: Organization, structure, and assembly of immunoglobulin heavy chain diversity DNA segments.
Volume: 155
Issue: 1
Pages: 201-18
Publication
First Author: Reininger L
Year: 1987
Journal: J Immunol
Title: Novel V genes encode virtually identical variable regions of six murine monoclonal anti-bromelain-treated red blood cell autoantibodies.
Volume: 138
Issue: 1
Pages: 316-23
Publication
First Author: Suzow J
Year: 1993
Journal: Mol Cell Biol
Title: The murine myeloperoxidase promoter contains several functional elements, one of which binds a cell type-restricted transcription factor, myeloid nuclear factor 1 (MyNF1).
Volume: 13
Issue: 4
Pages: 2141-51
Publication
First Author: Berberich S
Year: 1994
Journal: Oncogene
Title: The mdm-2 oncogene is translocated and overexpressed in a murine plasmacytoma cell line expressing wild-type p53.
Volume: 9
Issue: 5
Pages: 1469-72
Publication
First Author: Asakura K
Year: 1995
Journal: Brain Res Mol Brain Res
Title: Oligodendrocyte-reactive O1, O4, and HNK-1 monoclonal antibodies are encoded by germline immunoglobulin genes.
Volume: 34
Issue: 2
Pages: 283-93
Publication
First Author: Tsai YT
Year: 2014
Journal: J Neurochem
Title: Epigenetic activation of mouse ganglioside synthase genes: implications for neurogenesis.
Volume: 128
Issue: 1
Pages: 101-10
Publication
First Author: Suske G
Year: 2017
Journal: Biochim Biophys Acta
Title: NF-Y and SP transcription factors - New insights in a long-standing liaison.
Volume: 1860
Issue: 5
Pages: 590-597
Publication
First Author: Mirza S
Year: 2010
Journal: J Biol Chem
Title: Two modes of beta-receptor recognition are mediated by distinct epitopes on mouse and human interleukin-3.
Volume: 285
Issue: 29
Pages: 22370-81
Publication
First Author: Fitzgerald CT
Year: 1998
Journal: DNA Cell Biol
Title: Regulation of mouse Ah receptor (Ahr) gene basal expression by members of the Sp family of transcription factors.
Volume: 17
Issue: 9
Pages: 811-22
Publication
First Author: Okazaki N
Year: 2004
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 11
Issue: 3
Pages: 205-18
Publication
First Author: Carninci P
Year: 2000
Journal: Genome Res
Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.
Volume: 10
Issue: 10
Pages: 1617-30
Publication  
First Author: Carninci P
Year: 1999
Journal: Methods Enzymol
Title: High-efficiency full-length cDNA cloning.
Volume: 303
Pages: 19-44
Publication
First Author: Shibata K
Year: 2000
Journal: Genome Res
Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.
Volume: 10
Issue: 11
Pages: 1757-71
Publication
First Author: Katayama S
Year: 2005
Journal: Science
Title: Antisense transcription in the mammalian transcriptome.
Volume: 309
Issue: 5740
Pages: 1564-6
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
Publication
First Author: Church DM
Year: 2009
Journal: PLoS Biol
Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.
Volume: 7
Issue: 5
Pages: e1000112