Type |
Details |
Score |
Publication |
First Author: |
Fernández-García V |
Year: |
2022 |
Journal: |
Biomed Pharmacother |
Title: |
NOD1 splenic activation confers ferroptosis protection and reduces macrophage recruitment under pro-atherogenic conditions. |
Volume: |
148 |
|
Pages: |
112769 |
|
•
•
•
•
•
|
HT Experiment |
Series Id: |
GSE23497 |
Experiment Type: |
transcription profiling by array |
Study Type: |
WT vs. Mutant |
Source: |
ArrayExpress |
|
•
•
•
•
•
|
Publication |
First Author: |
Li SK |
Year: |
2015 |
Journal: |
J Immunol |
Title: |
Identification of a negative regulatory role for spi-C in the murine B cell lineage. |
Volume: |
194 |
Issue: |
8 |
Pages: |
3798-807 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kosoy R |
Year: |
2005 |
Journal: |
Genes Immun |
Title: |
Functional variants in SUMO4, TAB2, and NFkappaB and the risk of type 1 diabetes. |
Volume: |
6 |
Issue: |
3 |
Pages: |
231-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park JH |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs. |
Volume: |
178 |
Issue: |
4 |
Pages: |
2380-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim DJ |
Year: |
2013 |
Journal: |
Eur J Immunol |
Title: |
The Cag pathogenicity island and interaction between TLR2/NOD2 and NLRP3 regulate IL-1β production in Helicobacter pylori infected dendritic cells. |
Volume: |
43 |
Issue: |
10 |
Pages: |
2650-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shaw PJ |
Year: |
2011 |
Journal: |
Immunity |
Title: |
Signaling via the RIP2 adaptor protein in central nervous system-infiltrating dendritic cells promotes inflammation and autoimmunity. |
Volume: |
34 |
Issue: |
1 |
Pages: |
75-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vlacil AK |
Year: |
2020 |
Journal: |
Basic Res Cardiol |
Title: |
Deficiency of Nucleotide-binding oligomerization domain-containing proteins (NOD) 1 and 2 reduces atherosclerosis. |
Volume: |
115 |
Issue: |
4 |
Pages: |
47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Amer A |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf. |
Volume: |
281 |
Issue: |
46 |
Pages: |
35217-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ferwerda G |
Year: |
2005 |
Journal: |
PLoS Pathog |
Title: |
NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis. |
Volume: |
1 |
Issue: |
3 |
Pages: |
279-85 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yu AI |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
Gut Microbiota Modulate CD8 T Cell Responses to Influence Colitis-Associated Tumorigenesis. |
Volume: |
31 |
Issue: |
1 |
Pages: |
107471 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dooher JE |
Year: |
2011 |
Journal: |
Mol Cancer Res |
Title: |
C/EBPα, C/EBPα oncoproteins, or C/EBPβ preferentially bind NF-κB p50 compared with p65, focusing therapeutic targeting on the C/EBP:p50 interaction. |
Volume: |
9 |
Issue: |
10 |
Pages: |
1395-405 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nollet M |
Year: |
2014 |
Journal: |
Autophagy |
Title: |
Autophagy in osteoblasts is involved in mineralization and bone homeostasis. |
Volume: |
10 |
Issue: |
11 |
Pages: |
1965-77 |
|
•
•
•
•
•
|
Publication |
First Author: |
Su Y |
Year: |
2023 |
Journal: |
Theranostics |
Title: |
Inactivating IL34 promotes regenerating muscle stem cell expansion and attenuates Duchenne muscular dystrophy in mouse models. |
Volume: |
13 |
Issue: |
8 |
Pages: |
2588-2604 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sowa AK |
Year: |
2013 |
Journal: |
Am J Pathol |
Title: |
Functional interaction of osteogenic transcription factors Runx2 and Vdr in transcriptional regulation of Opn during soft tissue calcification. |
Volume: |
183 |
Issue: |
1 |
Pages: |
60-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ippagunta SK |
Year: |
2012 |
Journal: |
Nat Immunol |
Title: |
Addendum: defective Dock2 expression in a subset of ASC-deficient mouse lines. |
Volume: |
13 |
Issue: |
7 |
Pages: |
701-2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Anand PK |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
TLR2 and RIP2 pathways mediate autophagy of Listeria monocytogenes via extracellular signal-regulated kinase (ERK) activation. |
Volume: |
286 |
Issue: |
50 |
Pages: |
42981-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ermann J |
Year: |
2014 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Nod/Ripk2 signaling in dendritic cells activates IL-17A-secreting innate lymphoid cells and drives colitis in T-bet-/-.Rag2-/- (TRUC) mice. |
Volume: |
111 |
Issue: |
25 |
Pages: |
E2559-66 |
|
•
•
•
•
•
|
Publication |
First Author: |
Motomura Y |
Year: |
2015 |
Journal: |
Arterioscler Thromb Vasc Biol |
Title: |
Identification of Pathogenic Cardiac CD11c+ Macrophages in Nod1-Mediated Acute Coronary Arteritis. |
Volume: |
35 |
Issue: |
6 |
Pages: |
1423-33 |
|
•
•
•
•
•
|
Allele |
Name: |
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105; targeted mutation 1, David Baltimore |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Publication |
First Author: |
Meunier C |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Positional mapping and candidate gene analysis of the mouse Ccs3 locus that regulates differential susceptibility to carcinogen-induced colorectal cancer. |
Volume: |
8 |
Issue: |
3 |
Pages: |
e58733 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alkaissi H |
Year: |
2018 |
Journal: |
PLoS One |
Title: |
Bank1 and NF-kappaB as key regulators in anti-nucleolar antibody development. |
Volume: |
13 |
Issue: |
7 |
Pages: |
e0199979 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang S |
Year: |
2019 |
Journal: |
Sci Rep |
Title: |
FOXS1 is regulated by GLI1 and miR-125a-5p and promotes cell proliferation and EMT in gastric cancer. |
Volume: |
9 |
Issue: |
1 |
Pages: |
5281 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oosting M |
Year: |
2012 |
Journal: |
Arthritis Res Ther |
Title: |
Murine Borrelia arthritis is highly dependent on ASC and caspase-1, but independent of NLRP3. |
Volume: |
14 |
Issue: |
6 |
Pages: |
R247 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kanneganti TD |
Year: |
2007 |
Journal: |
Immunity |
Title: |
Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. |
Volume: |
26 |
Issue: |
4 |
Pages: |
433-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hasegawa M |
Year: |
2010 |
Journal: |
Infect Immun |
Title: |
Transitions in oral and intestinal microflora composition and innate immune receptor-dependent stimulation during mouse development. |
Volume: |
78 |
Issue: |
2 |
Pages: |
639-50 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant strain, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, targeted mutation, congenic |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 Nfkbia/Nfkbia |
Background: |
involves: 129S4/SvJae * C57BL/6J |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 Rela/Rela Tnf/Tnf |
Background: |
involves: 129P2/OlaHsd * 129S1/Sv * 129S4/SvJae |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 |
Background: |
B6;129P-Nfkb1/J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 Rel/Rel |
Background: |
involves: 129P2/OlaHsd * 129S1/Sv |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 Rela/Rela |
Background: |
involves: 129P2/OlaHsd * 129S4/SvJae |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 |
Background: |
involves: 129P2/OlaHsd |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 Rela/Rela<+> |
Background: |
involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 Tg(Tnfsf13b)1Fma/? |
Background: |
B6.Cg-Nfkb1 Tg(Tnfsf13b)1Fma |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 |
Background: |
B6.Cg-Nfkb1/J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 Nfkb2/Nfkb2 |
Background: |
involves: 129P2/OlaHsd * 129S4/SvJae |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Mir146/Mir146 Nfkb1/Nfkb1 |
Background: |
involves: 129P2/OlaHsd * C57BL/6 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nfkb1/Nfkb1 Rel/Rel Rela/Rela Tg(Cd4-cre)1Cwi/? |
Background: |
involves: 129 * 129P2/OlaHsd * C57BL/6J |
Zygosity: |
cn |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Bharadwaj R |
Year: |
2023 |
Journal: |
Immunity |
Title: |
Methotrexate suppresses psoriatic skin inflammation by inhibiting muropeptide transporter SLC46A2 activity. |
Volume: |
56 |
Issue: |
5 |
Pages: |
998-1012.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kamimura Y |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
Homeostatic control of memory cell progenitors in the natural killer cell lineage. |
Volume: |
10 |
Issue: |
2 |
Pages: |
280-91 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
467
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
467
|
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
467
|
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Kayagaki N |
Year: |
2011 |
Journal: |
Nature |
Title: |
Non-canonical inflammasome activation targets caspase-11. |
Volume: |
479 |
Issue: |
7371 |
Pages: |
117-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
McWhirter SM |
Year: |
2009 |
Journal: |
J Exp Med |
Title: |
A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP. |
Volume: |
206 |
Issue: |
9 |
Pages: |
1899-911 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karki R |
Year: |
2015 |
Journal: |
Cell Host Microbe |
Title: |
Concerted activation of the AIM2 and NLRP3 inflammasomes orchestrates host protection against Aspergillus infection. |
Volume: |
17 |
Issue: |
3 |
Pages: |
357-368 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shenderov K |
Year: |
2013 |
Journal: |
J Immunol |
Title: |
Cord factor and peptidoglycan recapitulate the Th17-promoting adjuvant activity of mycobacteria through mincle/CARD9 signaling and the inflammasome. |
Volume: |
190 |
Issue: |
11 |
Pages: |
5722-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kang SJ |
Year: |
2008 |
Journal: |
Immunity |
Title: |
Regulation of hierarchical clustering and activation of innate immune cells by dendritic cells. |
Volume: |
29 |
Issue: |
5 |
Pages: |
819-33 |
|
•
•
•
•
•
|