|  Help  |  About  |  Contact Us

Search our database by keyword

- or -

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 319 for Cbl

Category restricted to Publication (x)

<< First    < Previous  |  Next >    Last >>
0.042s

Categories

Category: Publication
« show all
Type Details Score
Publication
10393178 | J:56338
First Author: Lee PS
Year: 1999
Journal: EMBO J
Title: The Cbl protooncoprotein stimulates CSF-1 receptor multiubiquitination and endocytosis, and attenuates macrophage proliferation.
Volume: 18
Issue: 13
Pages: 3616-28
•
•
•
•
•
Publication
9653117 | J:48737
First Author: Miyake S
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: The tyrosine kinase regulator Cbl enhances the ubiquitination and degradation of the platelet-derived growth factor receptor alpha.
Volume: 95
Issue: 14
Pages: 7927-32
•
•
•
•
•
Publication
8770364 | J:36118
First Author: Langdon WY
Year: 1995
Journal: Aust N Z J Med
Title: The cbl oncogene: a novel substrate of protein tyrosine kinases.
Volume: 25
Issue: 6
Pages: 859-64
•
•
•
•
•
Publication
29237719 | J:281256
First Author: Schmid FM
Year: 2018
Journal: J Cell Biol
Title: IFT20 modulates ciliary PDGFRα signaling by regulating the stability of Cbl E3 ubiquitin ligases.
Volume: 217
Issue: 1
Pages: 151-161
•
•
•
•
•
Publication
19074136 | J:147595
First Author: Chiang YJ
Year: 2009
Journal: J Biol Chem
Title: Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.
Volume: 284
Issue: 7
Pages: 4429-38
•
•
•
•
•
Publication
24113870 | J:328418
First Author: Bulut GB
Year: 2013
Journal: Blood
Title: Cbl ubiquitination of p85 is essential for Epo-induced EpoR endocytosis.
Volume: 122
Issue: 24
Pages: 3964-72
•
•
•
•
•
Publication
12671687 | J:115703
First Author: Shao Y
Year: 2003
Journal: EMBO Rep
Title: Negative regulation of Rap1 activation by the Cbl E3 ubiquitin ligase.
Volume: 4
Issue: 4
Pages: 425-31
•
•
•
•
•
Publication
21490975 | J:172283
First Author: Chiang J
Year: 2011
Journal: PLoS One
Title: Cbl enforces Vav1 dependence and a restricted pathway of T cell development.
Volume: 6
Issue: 4
Pages: e18542
•
•
•
•
•
Publication
2030914 | J:37010
First Author: Blake TJ
Year: 1991
Journal: Oncogene
Title: The sequences of the human and mouse c-cbl proto-oncogenes show v-cbl was generated by a large truncation encompassing a proline-rich domain and a leucine zipper-like motif.
Volume: 6
Issue: 4
Pages: 653-7
•
•
•
•
•
Publication
29562201 | J:272419
First Author: Li X
Year: 2018
Journal: Immunity
Title: Cbl Ubiquitin Ligases Control B Cell Exit from the Germinal-Center Reaction.
Volume: 48
Issue: 3
Pages: 530-541.e6
•
•
•
•
•
Publication
17493844 | J:123596
First Author: Kitaura Y
Year: 2007
Journal: Immunity
Title: Control of the B cell-intrinsic tolerance programs by ubiquitin ligases Cbl and Cbl-b.
Volume: 26
Issue: 5
Pages: 567-78
•
•
•
•
•
Publication
16494846 | J:106781
First Author: Gupte A
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Activation of the Cbl insulin signaling pathway in cardiac muscle; dysregulation in obesity and diabetes.
Volume: 342
Issue: 3
Pages: 751-7
•
•
•
•
•
Publication
32584413 | J:305085
 
First Author: Li X
Year: 2020
Journal: J Exp Med
Title: Cbl and Cbl-b control the germinal center reaction by facilitating naive B cell antigen processing.
Volume: 217
Issue: 9
•
•
•
•
•
Publication
12652654 | J:82782
First Author: Caveggion E
Year: 2003
Journal: J Cell Physiol
Title: Expression and tyrosine phosphorylation of Cbl regulates macrophage chemokinetic and chemotactic movement.
Volume: 195
Issue: 2
Pages: 276-89
•
•
•
•
•
Publication
28100467 | J:245033
First Author: Mohapatra B
Year: 2017
Journal: Development
Title: An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance.
Volume: 144
Issue: 6
Pages: 1072-1086
•
•
•
•
•
Publication
8798454 | J:35411
First Author: Latour S
Year: 1996
Journal: J Biol Chem
Title: Differential intrinsic enzymatic activity of Syk and Zap-70 protein-tyrosine kinases.
Volume: 271
Issue: 37
Pages: 22782-90
•
•
•
•
•
Publication
8551236 | J:35635
First Author: Fournel M
Year: 1996
Journal: J Exp Med
Title: Association of tyrosine protein kinase Zap-70 with the protooncogene product p120c-cbl in T lymphocytes.
Volume: 183
Issue: 1
Pages: 301-6
•
•
•
•
•
Publication
34630435 | J:312696
 
First Author: Tong H
Year: 2021
Journal: Front Immunol
Title: Ubiquitin Ligases CBL and CBL-B Maintain the Homeostasis and Immune Quiescence of Dendritic Cells.
Volume: 12
Pages: 757231
•
•
•
•
•
Publication
27449297 | J:302686
First Author: An W
Year: 2016
Journal: Oncotarget
Title: VAV1-Cre mediated hematopoietic deletion of CBL and CBL-B leads to JMML-like aggressive early-neonatal myeloproliferative disease.
Volume: 7
Issue: 37
Pages: 59006-59016
•
•
•
•
•
Publication
38019655 | J:347517
First Author: Henry CM
Year: 2023
Journal: Cell Rep
Title: SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells.
Volume: 42
Issue: 12
Pages: 113506
•
•
•
•
•
Publication
25871390 | J:302741
First Author: An W
Year: 2015
Journal: Oncotarget
Title: Loss of Cbl and Cbl-b ubiquitin ligases abrogates hematopoietic stem cell quiescence and sensitizes leukemic disease to chemotherapy.
Volume: 6
Issue: 12
Pages: 10498-509
•
•
•
•
•
Publication
9890970 | J:200344
First Author: Hunter S
Year: 1999
Journal: J Biol Chem
Title: Fyn associates with Cbl and phosphorylates tyrosine 731 in Cbl, a binding site for phosphatidylinositol 3-kinase.
Volume: 274
Issue: 4
Pages: 2097-106
•
•
•
•
•
Publication
17045823 | J:114877
First Author: Huang F
Year: 2006
Journal: Immunity
Title: Establishment of the major compatibility complex-dependent development of CD4+ and CD8+ T cells by the Cbl family proteins.
Volume: 25
Issue: 4
Pages: 571-81
•
•
•
•
•
Publication
28611190 | J:243931
First Author: Lv K
Year: 2017
Journal: Genes Dev
Title: CBL family E3 ubiquitin ligases control JAK2 ubiquitination and stability in hematopoietic stem cells and myeloid malignancies.
Volume: 31
Issue: 10
Pages: 1007-1023
•
•
•
•
•
Publication
23457600 | J:199397
First Author: Wang L
Year: 2013
Journal: PLoS One
Title: Berberine inhibits proliferation and down-regulates epidermal growth factor receptor through activation of Cbl in colon tumor cells.
Volume: 8
Issue: 2
Pages: e56666
•
•
•
•
•
Publication
9687507 | J:114192
First Author: Meng F
Year: 1998
Journal: EMBO J
Title: A beta 1 integrin signaling pathway involving Src-family kinases, Cbl and PI-3 kinase is required for macrophage spreading and migration.
Volume: 17
Issue: 15
Pages: 4391-403
•
•
•
•
•
Publication
21703542 | J:173993
First Author: Schnyder T
Year: 2011
Journal: Immunity
Title: B cell receptor-mediated antigen gathering requires ubiquitin ligase Cbl and adaptors Grb2 and Dok-3 to recruit dynein to the signaling microcluster.
Volume: 34
Issue: 6
Pages: 905-18
•
•
•
•
•
Publication
19380812 | J:147711
First Author: Dale BM
Year: 2009
Journal: J Immunol
Title: Phagocytosis in macrophages lacking Cbl reveals an unsuspected role for Fc gamma receptor signaling and actin assembly in target binding.
Volume: 182
Issue: 9
Pages: 5654-62
•
•
•
•
•
Publication
27474268 | J:239186
First Author: Voisinne G
Year: 2016
Journal: Mol Syst Biol
Title: Co-recruitment analysis of the CBL and CBLB signalosomes in primary T cells identifies CD5 as a key regulator of TCR-induced ubiquitylation.
Volume: 12
Issue: 7
Pages: 876
•
•
•
•
•
Publication
38761804 | J:354878
First Author: Li X
Year: 2024
Journal: Immunity
Title: Deficiency of CBL and CBLB ubiquitin ligases leads to hyper T follicular helper cell responses and lupus by reducing BCL6 degradation.
Volume: 57
Issue: 7
Pages: 1603-1617.e7
•
•
•
•
•
Publication
8627181 | J:305755
First Author: Tezuka T
Year: 1996
Journal: J Exp Med
Title: Physical and functional association of the cbl protooncogen product with an src-family protein tyrosine kinase, p53/56lyn, in the B cell antigen receptor-mediated signaling.
Volume: 183
Issue: 2
Pages: 675-80
•
•
•
•
•
Publication
18034775 | J:177152
First Author: Fasen K
Year: 2008
Journal: Traffic
Title: Ligand binding induces Cbl-dependent EphB1 receptor degradation through the lysosomal pathway.
Volume: 9
Issue: 2
Pages: 251-66
•
•
•
•
•
Publication
12024036 | J:76785
First Author: Loreto MP
Year: 2002
Journal: Mol Cell Biol
Title: Functional cooperation between c-Cbl and Src-like adaptor protein 2 in the negative regulation of T-cell receptor signaling.
Volume: 22
Issue: 12
Pages: 4241-55
•
•
•
•
•
Publication
9824625 | -
First Author: Ollendorff V
Year: 1998
Journal: Int J Oncol
Title: A third human CBL gene is on chromosome 19.
Volume: 13
Issue: 6
Pages: 1159-61
•
•
•
•
•
Publication
26393915 | J:227226
First Author: Scanlon V
Year: 2015
Journal: PLoS One
Title: Role of Cbl-PI3K Interaction during Skeletal Remodeling in a Murine Model of Bone Repair.
Volume: 10
Issue: 9
Pages: e0138194
•
•
•
•
•
Publication
31299383 | J:294733
 
First Author: Yu J
Year: 2019
Journal: Bone
Title: Cbl-PI3K interaction regulates Cathepsin K secretion in osteoclasts.
Volume: 127
Pages: 376-385
•
•
•
•
•
Publication
28209720 | J:241533
First Author: Nakata Y
Year: 2017
Journal: Blood
Title: Acquired expression of CblQ367P in mice induces dysplastic myelopoiesis mimicking chronic myelomonocytic leukemia.
Volume: 129
Issue: 15
Pages: 2148-2160
•
•
•
•
•
Publication
20851882 | J:167020
First Author: Adapala NS
Year: 2010
Journal: J Biol Chem
Title: The loss of Cbl-phosphatidylinositol 3-kinase interaction perturbs RANKL-mediated signaling, inhibiting bone resorption and promoting osteoclast survival.
Volume: 285
Issue: 47
Pages: 36745-58
•
•
•
•
•
Publication
31665177 | J:281600
First Author: Doherty L
Year: 2019
Journal: PLoS One
Title: A PDGFRβ-PI3K signaling axis mediates periosteal cell activation during fracture healing.
Volume: 14
Issue: 10
Pages: e0223846
•
•
•
•
•
Publication
24994594 | J:215452
 
First Author: Adapala NS
Year: 2014
Journal: Bone
Title: Loss of Cbl-PI3K interaction in mice prevents significant bone loss following ovariectomy.
Volume: 67
Pages: 1-9
•
•
•
•
•
Publication
21830225 | J:227464
First Author: Feng L
Year: 2011
Journal: Cell Biochem Funct
Title: SH3KBP1-binding protein 1 prevents epidermal growth factor receptor degradation by the interruption of c-Cbl-CIN85 complex.
Volume: 29
Issue: 7
Pages: 589-96
•
•
•
•
•
Publication
27884787 | J:255148
 
First Author: Scanlon V
Year: 2017
Journal: Bone
Title: Loss of Cbl-PI3K interaction modulates the periosteal response to fracture by enhancing osteogenic commitment and differentiation.
Volume: 95
Pages: 124-135
•
•
•
•
•
Publication
9447983 | J:46223
First Author: Ribon V
Year: 1998
Journal: Mol Cell Biol
Title: A novel, multifuntional c-Cbl binding protein in insulin receptor signaling in 3T3-L1 adipocytes.
Volume: 18
Issue: 2
Pages: 872-9
•
•
•
•
•
Publication
23374343 | J:193456
First Author: Chen W
Year: 2013
Journal: Cell
Title: Induction of Siglec-G by RNA viruses inhibits the innate immune response by promoting RIG-I degradation.
Volume: 152
Issue: 3
Pages: 467-78
•
•
•
•
•
Publication
24470255 | J:244051
First Author: Adapala NS
Year: 2014
Journal: J Cell Biochem
Title: Loss of Cbl-PI3K interaction enhances osteoclast survival due to p21-Ras mediated PI3K activation independent of Cbl-b.
Volume: 115
Issue: 7
Pages: 1277-89
•
•
•
•
•
Publication
32954656 | J:329627
First Author: Märklin M
Year: 2020
Journal: J Cell Mol Med
Title: C-Cbl regulates c-MPL receptor trafficking and its internalization.
Volume: 24
Issue: 21
Pages: 12491-12503
•
•
•
•
•
Publication
17130487 | J:121012
First Author: Molero JC
Year: 2006
Journal: Diabetes
Title: Genetic ablation of the c-Cbl ubiquitin ligase domain results in increased energy expenditure and improved insulin action.
Volume: 55
Issue: 12
Pages: 3411-7
•
•
•
•
•
Publication
21967979 | J:178858
First Author: Buitrago L
Year: 2011
Journal: Blood
Title: Tyrosine phosphorylated c-Cbl regulates platelet functional responses mediated by outside-in signaling.
Volume: 118
Issue: 20
Pages: 5631-40
•
•
•
•
•
Publication
20133944 | J:161184
First Author: Thien CB
Year: 2010
Journal: J Biol Chem
Title: c-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.
Volume: 285
Issue: 14
Pages: 10969-81
•
•
•
•
•
Publication
15304502 | J:119327
First Author: Shao Y
Year: 2004
Journal: J Biol Chem
Title: Differential regulation of the B cell receptor-mediated signaling by the E3 ubiquitin ligase Cbl.
Volume: 279
Issue: 42
Pages: 43646-53
•
•
•
•
•
Publication
12415267 | J:80427
First Author: Naramura M
Year: 2002
Journal: Nat Immunol
Title: c-Cbl and Cbl-b regulate T cell responsiveness by promoting ligand-induced TCR down-modulation.
Volume: 3
Issue: 12
Pages: 1192-9
•
•
•
•
•
Publication
24440350 | J:206833
First Author: Leiser D
Year: 2014
Journal: FEBS Lett
Title: Targeting of the MET receptor tyrosine kinase by small molecule inhibitors leads to MET accumulation by impairing the receptor downregulation.
Volume: 588
Issue: 5
Pages: 653-8
•
•
•
•
•
Publication
12591907 | J:81965
First Author: Thien CB
Year: 2003
Journal: J Exp Med
Title: A mouse with a loss-of-function mutation in the c-Cbl TKB domain shows perturbed thymocyte signaling without enhancing the activity of the ZAP-70 tyrosine kinase.
Volume: 197
Issue: 4
Pages: 503-13
•
•
•
•
•
Publication
16301331 | J:104535
First Author: El Chami N
Year: 2005
Journal: J Cell Biol
Title: Androgen-dependent apoptosis in male germ cells is regulated through the proto-oncoprotein Cbl.
Volume: 171
Issue: 4
Pages: 651-61
•
•
•
•
•
Publication
12754251 | J:335499
First Author: Duan L
Year: 2003
Journal: J Biol Chem
Title: Cbl-mediated ubiquitinylation is required for lysosomal sorting of epidermal growth factor receptor but is dispensable for endocytosis.
Volume: 278
Issue: 31
Pages: 28950-60
•
•
•
•
•
Publication
23127761 | J:214050
First Author: Polzer H
Year: 2013
Journal: Exp Hematol
Title: Casitas B-lineage lymphoma mutants activate AKT to induce transformation in cooperation with class III receptor tyrosine kinases.
Volume: 41
Issue: 3
Pages: 271-80.e4
•
•
•
•
•
Publication
9103201 | J:39570
First Author: Ota Y
Year: 1997
Journal: Science
Title: The product of the proto-oncogene c-cbl: a negative regulator of the Syk tyrosine kinase.
Volume: 276
Issue: 5311
Pages: 418-20
•
•
•
•
•
Publication
9671496 | J:76895
First Author: Murphy MA
Year: 1998
Journal: Mol Cell Biol
Title: Tissue hyperplasia and enhanced T-cell signalling via ZAP-70 in c-Cbl-deficient mice.
Volume: 18
Issue: 8
Pages: 4872-82
•
•
•
•
•
Publication
30118682 | J:348413
First Author: Penn BH
Year: 2018
Journal: Mol Cell
Title: An Mtb-Human Protein-Protein Interaction Map Identifies a Switch between Host Antiviral and Antibacterial Responses.
Volume: 71
Issue: 4
Pages: 637-648.e5
•
•
•
•
•
Publication
9861006 | J:51666
First Author: Naramura M
Year: 1998
Journal: Proc Natl Acad Sci U S A
Title: Altered thymic positive selection and intracellular signals in Cbl-deficient mice.
Volume: 95
Issue: 26
Pages: 15547-52
•
•
•
•
•
Publication
18566322 | J:138720
First Author: Slape C
Year: 2008
Journal: Blood
Title: Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.
Volume: 112
Issue: 5
Pages: 2017-9
•
•
•
•
•
Publication
20805496 | J:164365
First Author: Naramura M
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Rapidly fatal myeloproliferative disorders in mice with deletion of Casitas B-cell lymphoma (Cbl) and Cbl-b in hematopoietic stem cells.
Volume: 107
Issue: 37
Pages: 16274-9
•
•
•
•
•
Publication
15962011 | J:99577
First Author: Haglund K
Year: 2005
Journal: EMBO Rep
Title: Sprouty2 acts at the Cbl/CIN85 interface to inhibit epidermal growth factor receptor downregulation.
Volume: 6
Issue: 7
Pages: 635-41
•
•
•
•
•
Publication
27276677 | J:264175
First Author: Goetz B
Year: 2016
Journal: Oncotarget
Title: A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells.
Volume: 7
Issue: 32
Pages: 51107-51123
•
•
•
•
•
Publication
20037154 | J:159891
First Author: Kim JH
Year: 2010
Journal: J Biol Chem
Title: Negative feedback control of osteoclast formation through ubiquitin-mediated down-regulation of NFATc1.
Volume: 285
Issue: 8
Pages: 5224-31
•
•
•
•
•
Publication
11001060 | J:114794
First Author: Baumann CA
Year: 2000
Journal: Nature
Title: CAP defines a second signalling pathway required for insulin-stimulated glucose transport.
Volume: 407
Issue: 6801
Pages: 202-7
•
•
•
•
•
Publication
15265912 | J:92026
First Author: Zhang J
Year: 2004
Journal: J Immunol
Title: Inactivation of c-Cbl or Cbl-b differentially affects signaling from the high affinity IgE receptor.
Volume: 173
Issue: 3
Pages: 1811-8
•
•
•
•
•
Publication
25477210 | J:230916
First Author: Chiang YJ
Year: 2015
Journal: Int Immunol
Title: Regulation of T cell development by c-Cbl: essential role of Lck.
Volume: 27
Issue: 5
Pages: 245-51
•
•
•
•
•
Publication
27926878 | J:241670
First Author: Davidson D
Year: 2016
Journal: Cell Rep
Title: The Csk-Associated Adaptor PAG Inhibits Effector T Cell Activation in Cooperation with Phosphatase PTPN22 and Dok Adaptors.
Volume: 17
Issue: 10
Pages: 2776-2788
•
•
•
•
•
Publication
31260484 | J:277222
First Author: Daniels SR
Year: 2019
Journal: PLoS One
Title: Loss of function Cbl-c mutations in solid tumors.
Volume: 14
Issue: 7
Pages: e0219143
•
•
•
•
•
Publication
14739300 | J:89495
First Author: Miyazaki T
Year: 2004
Journal: J Biol Chem
Title: Src kinase activity is essential for osteoclast function.
Volume: 279
Issue: 17
Pages: 17660-6
•
•
•
•
•
Publication
19641021 | J:164485
First Author: Purev E
Year: 2009
Journal: Mol Biol Cell
Title: c-Cbl and Cbl-b act redundantly to protect osteoclasts from apoptosis and to displace HDAC6 from beta-tubulin, stabilizing microtubules and podosomes.
Volume: 20
Issue: 18
Pages: 4021-30
•
•
•
•
•
Publication
32145025 | J:305453
First Author: Roman-Trufero M
Year: 2020
Journal: Mol Biol Evol
Title: Evolution of an Amniote-Specific Mechanism for Modulating Ubiquitin Signaling via Phosphoregulation of the E2 Enzyme UBE2D3.
Volume: 37
Issue: 7
Pages: 1986-2001
•
•
•
•
•
Publication
9013636 | J:38675
First Author: Ojaniemi M
Year: 1997
Journal: J Biol Chem
Title: The proto-oncogene product p120(cbl) links c-Src and phosphatidylinositol 3'-kinase to the integrin signaling pathway.
Volume: 272
Issue: 6
Pages: 3780-7
•
•
•
•
•
Publication
15581362 | J:94676
First Author: Miura A
Year: 2004
Journal: Biochemistry
Title: Insulin substrates 1 and 2 are corequired for activation of atypical protein kinase C and Cbl-dependent phosphatidylinositol 3-kinase during insulin action in immortalized brown adipocytes.
Volume: 43
Issue: 49
Pages: 15503-9
•
•
•
•
•
Publication
15708558 | J:96235
First Author: Crowley MR
Year: 2005
Journal: Dev Biol
Title: TGF-beta, c-Cbl, and PDGFR-alpha the in mammary stroma.
Volume: 279
Issue: 1
Pages: 58-72
•
•
•
•
•
Publication
16455755 | J:107908
First Author: Fecchi K
Year: 2006
Journal: FASEB J
Title: Spatial and temporal regulation of GLUT4 translocation by flotillin-1 and caveolin-3 in skeletal muscle cells.
Volume: 20
Issue: 6
Pages: 705-7
•
•
•
•
•
Publication
16211006 | J:103366
First Author: Thien CB
Year: 2005
Journal: EMBO J
Title: Loss of c-Cbl RING finger function results in high-intensity TCR signaling and thymic deletion.
Volume: 24
Issue: 21
Pages: 3807-19
•
•
•
•
•
Publication
15520865 | J:94416
First Author: Molero JC
Year: 2004
Journal: J Clin Invest
Title: c-Cbl-deficient mice have reduced adiposity, higher energy expenditure, and improved peripheral insulin action.
Volume: 114
Issue: 9
Pages: 1326-33
•
•
•
•
•
Publication
24718698 | J:215094
First Author: Duyvestyn JM
Year: 2014
Journal: PLoS One
Title: Dasatinib targets B-lineage cells but does not provide an effective therapy for myeloproliferative disease in c-Cbl RING finger mutant mice.
Volume: 9
Issue: 4
Pages: e94717
•
•
•
•
•
Publication
20404156 | J:160327
First Author: Rathinam C
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: c-Cbl deficiency leads to diminished lymphocyte development and functions in an age-dependent manner.
Volume: 107
Issue: 18
Pages: 8316-21
•
•
•
•
•
Publication
16505234 | J:106854
First Author: Molero JC
Year: 2006
Journal: Diabetes
Title: Casitas b-lineage lymphoma-deficient mice are protected against high-fat diet-induced obesity and insulin resistance.
Volume: 55
Issue: 3
Pages: 708-15
•
•
•
•
•
Publication
19620960 | J:151543
First Author: Sanada M
Year: 2009
Journal: Nature
Title: Gain-of-function of mutated C-CBL tumour suppressor in myeloid neoplasms.
Volume: 460
Issue: 7257
Pages: 904-8
•
•
•
•
•
Publication
18413713 | J:133764
First Author: Rathinam C
Year: 2008
Journal: Genes Dev
Title: The E3 ubiquitin ligase c-Cbl restricts development and functions of hematopoietic stem cells.
Volume: 22
Issue: 8
Pages: 992-7
•
•
•
•
•
Publication
22990016 | J:191268
First Author: Taylor SJ
Year: 2012
Journal: Blood
Title: Flt3 inhibitor AC220 is a potent therapy in a mouse model of myeloproliferative disease driven by enhanced wild-type Flt3 signaling.
Volume: 120
Issue: 19
Pages: 4049-57
•
•
•
•
•
Publication
32386556 | J:329437
First Author: Spevak CC
Year: 2020
Journal: Cell Stem Cell
Title: Hematopoietic Stem and Progenitor Cells Exhibit Stage-Specific Translational Programs via mTOR- and CDK1-Dependent Mechanisms.
Volume: 26
Issue: 5
Pages: 755-765.e7
•
•
•
•
•
Publication
27156691 | J:317618
First Author: Dong L
Year: 2016
Journal: CNS Neurosci Ther
Title: The E3 Ubiquitin Ligase c-Cbl Inhibits Microglia-Mediated CNS Inflammation by Regulating PI3K/Akt/NF-κB Pathway.
Volume: 22
Issue: 8
Pages: 661-9
•
•
•
•
•
Publication
20085752 | J:157860
First Author: Demydenko D
Year: 2010
Journal: Biochem Biophys Res Commun
Title: c-Cbl mediated ubiquitylation and regulation of cell surface exposure of CD5.
Volume: 392
Issue: 4
Pages: 500-4
•
•
•
•
•
Publication
14499658 | J:85606
First Author: Chiusaroli R
Year: 2003
Journal: Dev Biol
Title: Deletion of the gene encoding c-Cbl alters the ability of osteoclasts to migrate, delaying resorption and ossification of cartilage during the development of long bones.
Volume: 261
Issue: 2
Pages: 537-47
•
•
•
•
•
Publication
20207996 | J:214649
First Author: Doherty M
Year: 2010
Journal: J Immunol
Title: Anergic CD4+ T cells form mature immunological synapses with enhanced accumulation of c-Cbl and Cbl-b.
Volume: 184
Issue: 7
Pages: 3598-608
•
•
•
•
•
Publication
2784003 | J:9637
First Author: Langdon WY
Year: 1989
Journal: Proc Natl Acad Sci U S A
Title: v-cbl, an oncogene from a dual-recombinant murine retrovirus that induces early B-lineage lymphomas.
Volume: 86
Issue: 4
Pages: 1168-72
•
•
•
•
•
Publication
12707333 | J:123832
First Author: Niederberger N
Year: 2003
Journal: J Immunol
Title: Allelic exclusion of the TCR alpha-chain is an active process requiring TCR-mediated signaling and c-Cbl.
Volume: 170
Issue: 9
Pages: 4557-63
•
•
•
•
•
Publication
21118980 | J:167131
First Author: Mao JH
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: As4S4 targets RING-type E3 ligase c-CBL to induce degradation of BCR-ABL in chronic myelogenous leukemia.
Volume: 107
Issue: 50
Pages: 21683-8
•
•
•
•
•
Publication
22645367 | J:185520
First Author: Kundrotas PJ
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Templates are available to model nearly all complexes of structurally characterized proteins.
Volume: 109
Issue: 24
Pages: 9438-41
•
•
•
•
•
Publication
23533197 | J:198366
First Author: Dieudonne FX
Year: 2013
Journal: Stem Cells
Title: Promotion of osteoblast differentiation in mesenchymal cells through Cbl-mediated control of STAT5 activity.
Volume: 31
Issue: 7
Pages: 1340-9
•
•
•
•
•
Publication
14657036 | J:87072
First Author: Akiyama T
Year: 2003
Journal: EMBO J
Title: Regulation of osteoclast apoptosis by ubiquitylation of proapoptotic BH3-only Bcl-2 family member Bim.
Volume: 22
Issue: 24
Pages: 6653-64
•
•
•
•
•
Publication
17938199 | J:129025
First Author: Balagopalan L
Year: 2007
Journal: Mol Cell Biol
Title: c-Cbl-mediated regulation of LAT-nucleated signaling complexes.
Volume: 27
Issue: 24
Pages: 8622-36
•
•
•
•
•
Publication
19904769 | J:157790
First Author: Mamchak AA
Year: 2010
Journal: Eur J Immunol
Title: Unaltered negative selection and Treg development of self-reactive thymocytes in TCR transgenic Fyn-deficient mice.
Volume: 40
Issue: 2
Pages: 539-47
•
•
•
•
•
Publication
19597496 | J:151578
First Author: Kundu M
Year: 2009
Journal: Nat Immunol
Title: A TNF- and c-Cbl-dependent FLIP(S)-degradation pathway and its function in Mycobacterium tuberculosis-induced macrophage apoptosis.
Volume: 10
Issue: 8
Pages: 918-26
•
•
•
•
•
Publication
17056522 | J:140531
First Author: Gustin SE
Year: 2006
Journal: J Immunol
Title: Cbl-b is a negative regulator of inflammatory cytokines produced by IgE-activated mast cells.
Volume: 177
Issue: 9
Pages: 5980-9
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom