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Search results 201 to 277 out of 277 for Nox1

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Type Details Score
Publication
17602954 | J:122814
First Author: Valente AJ
Year: 2007
Journal: Free Radic Biol Med
Title: NOX1 NADPH oxidase regulation by the NOXA1 SH3 domain.
Volume: 43
Issue: 3
Pages: 384-96
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Publication
17673675 | J:141346
First Author: Miller FJ Jr
Year: 2007
Journal: Circ Res
Title: Cytokine activation of nuclear factor kappa B in vascular smooth muscle cells requires signaling endosomes containing Nox1 and ClC-3.
Volume: 101
Issue: 7
Pages: 663-71
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Publication
25661082 | J:254189
First Author: Shaifta Y
Year: 2015
Journal: Cardiovasc Res
Title: Sphingosylphosphorylcholine potentiates vasoreactivity and voltage-gated Ca2+ entry via NOX1 and reactive oxygen species.
Volume: 106
Issue: 1
Pages: 121-30
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Publication
14617635 | -
First Author: Cheng G
Year: 2004
Journal: J Biol Chem
Title: NOXO1, regulation of lipid binding, localization, and activation of Nox1 by the Phox homology (PX) domain.
Volume: 279
Issue: 6
Pages: 4737-42
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Allele
Nox1<em1Smoc> | MGI:7291359
Name: NADPH oxidase 1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
15949904 | -
 
First Author: Cheng G
Year: 2005
Journal: Gene
Title: Alternative mRNA splice forms of NOXO1: differential tissue expression and regulation of Nox1 and Nox3.
Volume: 356
Pages: 118-26
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Strain
MGI:6429274 | C57BL/6J-Nox1<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Publication
12657628 | -
First Author: Geiszt M
Year: 2003
Journal: J Biol Chem
Title: Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells.
Volume: 278
Issue: 22
Pages: 20006-12
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Publication
22244833 | -
First Author: Kawano M
Year: 2012
Journal: Arch Biochem Biophys
Title: Noxa1 as a moderate activator of Nox2-based NADPH oxidase.
Volume: 519
Issue: 1
Pages: 1-7
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Publication
12716910 | -
First Author: Takeya R
Year: 2003
Journal: J Biol Chem
Title: Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases.
Volume: 278
Issue: 27
Pages: 25234-46
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Publication
20001746 | -
First Author: Petry A
Year: 2010
Journal: Antioxid Redox Signal
Title: Receptor activation of NADPH oxidases.
Volume: 13
Issue: 4
Pages: 467-87
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Publication
17126813 | -
First Author: Yamamoto A
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Interaction between the SH3 domains and C-terminal proline-rich region in NADPH oxidase organizer 1 (Noxo1).
Volume: 352
Issue: 2
Pages: 560-5
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Protein Domain
IPR034899 | NOXA1
Type: Family
Description: NADPH oxidase activator 1 (NOXA1), also known as p51-nox or p67phox-like factor, functions as an activator of NOX1 and NOX2, members of the Nox family of superoxide-producing NADPH oxidases []. It is homologous to the component p67-phox of the phagocytic oxidase, the prototypical Nox [, ]. NOXA1 and NOXO1 support superoxide generation by NOX1 and are expressed predominantly in colon epithelium with NOX1 []. NOXA1 is also coexpressed with NOX2 in some cells, such as endothelial cells, vascular smooth muscle cells, and hematopoietic stem cells [].
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Protein Domain
IPR035758 | NoxO1_SH3_2
Type: Domain
Description: Nox Organizing protein 1 (NoxO1) is a critical regulator of enzyme kinetics of the nonphagocytic NADPH oxidase Nox1, which catalyzes the transfer of electrons from NADPH to molecular oxygen to form superoxide []. NoxO1 is involved in targeting activator subunits (such as NoxA1) to Nox1. It is co-localized with Nox1 in the membranes of resting cells and directs the subcellular localization of Nox1 []. NoxO1 contains an N-terminal Phox homology (PX) domain, tandem SH3 domains (N-SH3 and C-SH3), and a C-terminal proline-rich region (PRR).This entry represents the second SH3 domain (or C-SH3) of NoxO1. The tandem SH3 domains of NoxO1 interact with the PRR of p22phox, which also complexes with Nox1 [].
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Allele
Nox1<tm1Kkr> | MGI:3616995
Name: NADPH oxidase 1; targeted mutation 1, Karl-Heinz Krause
Allele Type: Targeted
Attribute String: Null/knockout
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Publication
17237347 | -
First Author: Bedard K
Year: 2007
Journal: Physiol Rev
Title: The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology.
Volume: 87
Issue: 1
Pages: 245-313
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Strain
MGI:3617250 | B6.129X1-Nox1<tm1Kkr>
Attribute String: congenic, mutant strain, targeted mutation
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Strain
MGI:5427477 | B6.129X1-Nox1<tm1Kkr>/J
Attribute String: mutant strain, congenic, targeted mutation
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Allele
Tg(ACTB-EGFP,-NOX1)1Jdla | MGI:6159583
Name: transgene insertion 1, J Lambeth
Allele Type: Transgenic
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Genotype
Genotype
Symbol: Nox1/?
Background: B6.129X1-Nox1
Zygosity: ot
Has Mutant Allele: true
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Strain
MGI:6159587 | STOCK Tg(ACTB-EGFP,-NOX1)1Jdla/J
Attribute String: mutant stock, transgenic
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Publication
28132856 | J:243318
First Author: Raad H
Year: 2017
Journal: J Invest Dermatol
Title: NADPH Oxidase-1 Plays a Key Role in Keratinocyte Responses to UV Radiation and UVB-Induced Skin Carcinogenesis.
Volume: 137
Issue: 6
Pages: 1311-1321
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Publication
25437426 | J:220043
First Author: Hosseini M
Year: 2015
Journal: J Invest Dermatol
Title: Premature skin aging features rescued by inhibition of NADPH oxidase activity in XPC-deficient mice.
Volume: 135
Issue: 4
Pages: 1108-1118
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Publication
29192190 | J:257664
First Author: De Logu F
Year: 2017
Journal: Nat Commun
Title: Schwann cell TRPA1 mediates neuroinflammation that sustains macrophage-dependent neuropathic pain in mice.
Volume: 8
Issue: 1
Pages: 1887
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Publication
25947060 | J:222961
First Author: Morimoto H
Year: 2015
Journal: Biol Reprod
Title: ROS-Generating Oxidase Nox3 Regulates the Self-Renewal of Mouse Spermatogonial Stem Cells.
Volume: 92
Issue: 6
Pages: 147
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Protein
Q8VCM2
Organism: Mus musculus/domesticus
Length: 349  
Fragment?: false
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Protein
Q0VDT6
Organism: Mus musculus/domesticus
Length: 336  
Fragment?: true
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Publication
30948641 | J:277909
First Author: Xu H
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: VSMC-specific EP4 deletion exacerbates angiotensin II-induced aortic dissection by increasing vascular inflammation and blood pressure.
Volume: 116
Issue: 17
Pages: 8457-8462
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Publication
33914863 | J:332887
First Author: Wu JH
Year: 2022
Journal: Cardiovasc Res
Title: Drebrin attenuates atherosclerosis by limiting smooth muscle cell transdifferentiation.
Volume: 118
Issue: 3
Pages: 772-784
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Publication
27897258 | J:287364
 
First Author: Gortan Cappellari G
Year: 2016
Journal: Sci Rep
Title: Lack of Fibronectin Extra Domain A Alternative Splicing Exacerbates Endothelial Dysfunction in Diabetes.
Volume: 6
Pages: 37965
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Publication
32949971 | J:310485
 
First Author: Buchmann GK
Year: 2020
Journal: Redox Biol
Title: Deletion of NoxO1 limits atherosclerosis development in female mice.
Volume: 37
Pages: 101713
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Publication
33879616 | J:309678
 
First Author: Daneva Z
Year: 2021
Journal: Proc Natl Acad Sci U S A
Title: Caveolar peroxynitrite formation impairs endothelial TRPV4 channels and elevates pulmonary arterial pressure in pulmonary hypertension.
Volume: 118
Issue: 17
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Publication
20489161 | J:175050
First Author: Cheng SL
Year: 2010
Journal: Circ Res
Title: Activation of vascular smooth muscle parathyroid hormone receptor inhibits Wnt/beta-catenin signaling and aortic fibrosis in diabetic arteriosclerosis.
Volume: 107
Issue: 2
Pages: 271-82
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Publication
26945079 | J:233008
First Author: Onetti Y
Year: 2016
Journal: Am J Physiol Heart Circ Physiol
Title: NADPH oxidase 4 attenuates cerebral artery changes during the progression of Marfan syndrome.
Volume: 310
Issue: 9
Pages: H1081-90
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Publication
23557706 | J:208969
First Author: Eid AA
Year: 2013
Journal: Diabetes
Title: Mammalian target of rapamycin regulates Nox4-mediated podocyte depletion in diabetic renal injury.
Volume: 62
Issue: 8
Pages: 2935-47
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Publication
25656366 | J:280489
First Author: Gorin Y
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Targeting NADPH oxidase with a novel dual Nox1/Nox4 inhibitor attenuates renal pathology in type 1 diabetes.
Volume: 308
Issue: 11
Pages: F1276-87
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Publication
37310356 | J:338081
First Author: Choi H
Year: 2023
Journal: FASEB J
Title: LRRC8A anion channels modulate vascular reactivity via association with myosin phosphatase rho interacting protein.
Volume: 37
Issue: 7
Pages: e23028
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Publication
31656096 | J:327446
First Author: Bruder-Nascimento T
Year: 2019
Journal: Hypertension
Title: Leptin Restores Endothelial Function via Endothelial PPARγ-Nox1-Mediated Mechanisms in a Mouse Model of Congenital Generalized Lipodystrophy.
Volume: 74
Issue: 6
Pages: 1399-1408
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Publication
23049784 | J:191949
First Author: Sancho P
Year: 2012
Journal: PLoS One
Title: NADPH oxidase NOX4 mediates stellate cell activation and hepatocyte cell death during liver fibrosis development.
Volume: 7
Issue: 9
Pages: e45285
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Publication
36573349 | J:338498
First Author: Huang YJ
Year: 2023
Journal: Glia
Title: Astrocytic aryl hydrocarbon receptor mediates chronic kidney disease-associated mental disorders involving GLT1 hypofunction and neuronal activity enhancement in the mouse brain.
Volume: 71
Issue: 4
Pages: 1057-1080
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Publication
24587793 | J:286505
 
First Author: Vechoropoulos M
Year: 2014
Journal: PPAR Res
Title: The Proatherogenic Effect of Chronic Nitric Oxide Synthesis Inhibition in ApoE-Null Mice Is Dependent on the Presence of PPAR α.
Volume: 2014
Pages: 124583
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Publication
22896039 | J:189801
First Author: Hong NJ
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: NADPH oxidase 4 mediates flow-induced superoxide production in thick ascending limbs.
Volume: 303
Issue: 8
Pages: F1151-6
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Publication
23306835 | J:210132
First Author: Fu P
Year: 2013
Journal: Am J Respir Cell Mol Biol
Title: Role of nicotinamide adenine dinucleotide phosphate-reduced oxidase proteins in Pseudomonas aeruginosa-induced lung inflammation and permeability.
Volume: 48
Issue: 4
Pages: 477-88
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Publication
15753233 | J:134741
First Author: Touyz RM
Year: 2005
Journal: Hypertension
Title: Angiotensin II-dependent chronic hypertension and cardiac hypertrophy are unaffected by gp91phox-containing NADPH oxidase.
Volume: 45
Issue: 4
Pages: 530-7
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Publication
19969072 | J:156772
First Author: Mukhopadhyay P
Year: 2010
Journal: Free Radic Biol Med
Title: Cannabinoid-2 receptor limits inflammation, oxidative/nitrosative stress, and cell death in nephropathy.
Volume: 48
Issue: 3
Pages: 457-67
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Publication
27803283 | J:257937
First Author: Meyer MR
Year: 2016
Journal: Sci Signal
Title: Obligatory role for GPER in cardiovascular aging and disease.
Volume: 9
Issue: 452
Pages: ra105
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Publication
22749956 | J:186246
First Author: Babelova A
Year: 2012
Journal: Free Radic Biol Med
Title: Role of Nox4 in murine models of kidney disease.
Volume: 53
Issue: 4
Pages: 842-53
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Publication
34638939 | J:320800
 
First Author: Bruder-Nascimento T
Year: 2021
Journal: Int J Mol Sci
Title: Reduced Endothelial Leptin Signaling Increases Vascular Adrenergic Reactivity in a Mouse Model of Congenital Generalized Lipodystrophy.
Volume: 22
Issue: 19
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Publication
21071705 | J:184184
First Author: Chu X
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: A critical role for chloride channel-3 (CIC-3) in smooth muscle cell activation and neointima formation.
Volume: 31
Issue: 2
Pages: 345-51
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Publication
15471976 | J:95573
First Author: Laude K
Year: 2005
Journal: Am J Physiol Heart Circ Physiol
Title: Hemodynamic and biochemical adaptations to vascular smooth muscle overexpression of p22phox in mice.
Volume: 288
Issue: 1
Pages: H7-12
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Publication
16507596 | J:107002
First Author: Ateghang B
Year: 2006
Journal: J Cell Sci
Title: Regulation of cardiotrophin-1 expression in mouse embryonic stem cells by HIF-1alpha and intracellular reactive oxygen species.
Volume: 119
Issue: Pt 6
Pages: 1043-52
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Publication
15817678 | J:117323
First Author: Lee NK
Year: 2005
Journal: Blood
Title: A crucial role for reactive oxygen species in RANKL-induced osteoclast differentiation.
Volume: 106
Issue: 3
Pages: 852-9
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Publication
21415386 | J:191477
First Author: Ray R
Year: 2011
Journal: Arterioscler Thromb Vasc Biol
Title: Endothelial Nox4 NADPH oxidase enhances vasodilatation and reduces blood pressure in vivo.
Volume: 31
Issue: 6
Pages: 1368-76
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Publication
22427664 | J:193009
First Author: Ortiz C
Year: 2012
Journal: J Biol Chem
Title: Protein-tyrosine phosphatase 1B (PTP1B) deficiency confers resistance to transforming growth factor-β (TGF-β)-induced suppressor effects in hepatocytes.
Volume: 287
Issue: 19
Pages: 15263-74
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Publication
25576385 | J:219740
First Author: Lee SH
Year: 2015
Journal: Exp Cell Res
Title: Scoparone attenuates RANKL-induced osteoclastic differentiation through controlling reactive oxygen species production and scavenging.
Volume: 331
Issue: 2
Pages: 267-77
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Publication
26184677 | J:225900
First Author: Parajuli B
Year: 2015
Journal: Glia
Title: CCL11 enhances excitotoxic neuronal death by producing reactive oxygen species in microglia.
Volume: 63
Issue: 12
Pages: 2274-84
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Publication
28160092 | J:241229
First Author: Gray SP
Year: 2017
Journal: Diabetologia
Title: Combined NOX1/4 inhibition with GKT137831 in mice provides dose-dependent reno- and atheroprotection even in established micro- and macrovascular disease.
Volume: 60
Issue: 5
Pages: 927-937
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Publication
29908908 | J:270546
First Author: Liu L
Year: 2018
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Myocardin-related transcription factor A (MRTF-A) contributes to acute kidney injury by regulating macrophage ROS production.
Volume: 1864
Issue: 10
Pages: 3109-3121
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Publication
31445163 | J:282574
 
First Author: Shen Y
Year: 2019
Journal: Neurobiol Dis
Title: Smooth muscle cell-specific knockout of FBW7 exacerbates intracranial atherosclerotic stenosis.
Volume: 132
Pages: 104584
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Publication
25565313 | J:315367
First Author: Wang H
Year: 2015
Journal: Kidney Int
Title: p47(phox) contributes to albuminuria and kidney fibrosis in mice.
Volume: 87
Issue: 5
Pages: 948-62
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Publication
33227407 | J:313408
 
First Author: Fernandes DC
Year: 2021
Journal: Free Radic Biol Med
Title: PDIA1 acts as master organizer of NOX1/NOX4 balance and phenotype response in vascular smooth muscle.
Volume: 162
Pages: 603-614
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Protein
Q8CJ00
Organism: Mus musculus/domesticus
Length: 444  
Fragment?: false
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Publication
17490678 | J:123117
First Author: Ritchie RH
Year: 2007
Journal: J Mol Cell Cardiol
Title: The antioxidant tempol inhibits cardiac hypertrophy in the insulin-resistant GLUT4-deficient mouse in vivo.
Volume: 42
Issue: 6
Pages: 1119-28
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Publication
20167927 | J:171036
First Author: Wang S
Year: 2010
Journal: Circ Res
Title: AMPKalpha2 deletion causes aberrant expression and activation of NAD(P)H oxidase and consequent endothelial dysfunction in vivo: role of 26S proteasomes.
Volume: 106
Issue: 6
Pages: 1117-28
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Publication
22685265 | J:189093
First Author: Lai CF
Year: 2012
Journal: Endocrinology
Title: TNFR1-activated reactive oxidative species signals up-regulate osteogenic Msx2 programs in aortic myofibroblasts.
Volume: 153
Issue: 8
Pages: 3897-910
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Publication
22100343 | J:179385
First Author: Xu M
Year: 2012
Journal: Free Radic Biol Med
Title: NAD(P)H oxidase-dependent intracellular and extracellular O2•- production in coronary arterial myocytes from CD38 knockout mice.
Volume: 52
Issue: 2
Pages: 357-65
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Publication
20638362 | J:164600
First Author: Ge Y
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Mouse embryonic fibroblasts from CD38 knockout mice are resistant to oxidative stresses through inhibition of reactive oxygen species production and Ca(2+) overload.
Volume: 399
Issue: 2
Pages: 167-72
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Publication
22875785 | J:192783
First Author: Massey KJ
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Angiotensin II stimulates superoxide production in the thick ascending limb by activating NOX4.
Volume: 303
Issue: 7
Pages: C781-9
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Publication
36870375 | J:336333
 
First Author: Tu D
Year: 2023
Journal: Free Radic Biol Med
Title: Activation of neuronal NADPH oxidase NOX2 promotes inflammatory neurodegeneration.
Volume: 200
Pages: 47-58
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Publication
37401647 | J:342881
First Author: Yang K
Year: 2023
Journal: Cardiovasc Res
Title: Chronic SIRT1 supplementation in diabetic mice improves endothelial function by suppressing oxidative stress.
Volume: 119
Issue: 12
Pages: 2190-2201
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Publication
15388638 | J:103487
First Author: Sorescu GP
Year: 2004
Journal: Circ Res
Title: Bone morphogenic protein 4 produced in endothelial cells by oscillatory shear stress induces monocyte adhesion by stimulating reactive oxygen species production from a nox1-based NADPH oxidase.
Volume: 95
Issue: 8
Pages: 773-9
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Publication
24684302 | J:311460
First Author: Kwon MJ
Year: 2014
Journal: Endocrinology
Title: Deficiency of clusterin exacerbates high-fat diet-induced insulin resistance in male mice.
Volume: 155
Issue: 6
Pages: 2089-101
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Publication
31299613 | J:290932
 
First Author: García-Ruiz I
Year: 2019
Journal: Redox Biol
Title: Protein tyrosine phosphatase 1b deficiency protects against hepatic fibrosis by modulating nadph oxidases.
Volume: 26
Pages: 101263
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Publication
20454568 | J:160925
First Author: Dutta S
Year: 2010
Journal: PLoS One
Title: Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1.
Volume: 5
Issue: 5
Pages: e10478
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Publication
30925081 | J:275912
First Author: Choi H
Year: 2019
Journal: Am J Physiol Heart Circ Physiol
Title: Apoptosis signal-regulating kinase 1 activation by Nox1-derived oxidants is required for TNFα receptor endocytosis.
Volume: 316
Issue: 6
Pages: H1528-H1537
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Publication
30566058 | J:292013
First Author: Das S
Year: 2018
Journal: Circ Res
Title: A Novel Angiotensin II-Induced Long Noncoding RNA Giver Regulates Oxidative Stress, Inflammation, and Proliferation in Vascular Smooth Muscle Cells.
Volume: 123
Issue: 12
Pages: 1298-1312
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Publication
22806357 | J:318081
First Author: Aoyama T
Year: 2012
Journal: Hepatology
Title: Nicotinamide adenine dinucleotide phosphate oxidase in experimental liver fibrosis: GKT137831 as a novel potential therapeutic agent.
Volume: 56
Issue: 6
Pages: 2316-27
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