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Search results 201 to 285 out of 285 for Pdk4

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Type Details Score
Publication
23676500 | J:201436
First Author: Chang I
Year: 2013
Journal: J Clin Invest
Title: Endothelin-2 deficiency causes growth retardation, hypothermia, and emphysema in mice.
Volume: 123
Issue: 6
Pages: 2643-53
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Publication
26554594 | J:235909
First Author: Conrad E
Year: 2016
Journal: Am J Physiol Endocrinol Metab
Title: The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells.
Volume: 310
Issue: 1
Pages: E91-E102
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Publication
23968980 | J:222220
First Author: Iso T
Year: 2013
Journal: Arterioscler Thromb Vasc Biol
Title: Capillary endothelial fatty acid binding proteins 4 and 5 play a critical role in fatty acid uptake in heart and skeletal muscle.
Volume: 33
Issue: 11
Pages: 2549-57
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Publication
37225978 | J:340032
First Author: Paredes A
Year: 2023
Journal: Nature
Title: γ-Linolenic acid in maternal milk drives cardiac metabolic maturation.
Volume: 618
Issue: 7964
Pages: 365-373
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Publication
20185832 | J:162597
First Author: Hyvärinen J
Year: 2010
Journal: J Biol Chem
Title: Hearts of hypoxia-inducible factor prolyl 4-hydroxylase-2 hypomorphic mice show protection against acute ischemia-reperfusion injury.
Volume: 285
Issue: 18
Pages: 13646-57
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Publication
35237793 | J:321836
 
First Author: Zhao K
Year: 2022
Journal: Development
Title: LONP1-mediated mitochondrial quality control safeguards metabolic shifts in heart development.
Volume: 149
Issue: 6
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Publication
32212902 | J:317550
First Author: Sakamoto T
Year: 2020
Journal: Circ Res
Title: A Critical Role for Estrogen-Related Receptor Signaling in Cardiac Maturation.
Volume: 126
Issue: 12
Pages: 1685-1702
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Publication
27215380 | J:236179
First Author: Bowman CE
Year: 2016
Journal: Mol Cell Biol
Title: Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.
Volume: 36
Issue: 15
Pages: 2089-104
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Publication
12865426 | J:100953
First Author: Da Cruz S
Year: 2003
Journal: J Biol Chem
Title: Proteomic analysis of the mouse liver mitochondrial inner membrane.
Volume: 278
Issue: 42
Pages: 41566-71
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Publication
- | J:58777
     
First Author: Elliott R
Year: 2000
Journal: Personal Communication
Title: Chromosome Locations Based on RH mapping
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
14651853 | J:86816
First Author: Mootha VK
Year: 2003
Journal: Cell
Title: Integrated analysis of protein composition, tissue diversity, and gene regulation in mouse mitochondria.
Volume: 115
Issue: 5
Pages: 629-40
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
27626380 | J:236599
First Author: Dickinson ME
Year: 2016
Journal: Nature
Title: High-throughput discovery of novel developmental phenotypes.
Volume: 537
Issue: 7621
Pages: 508-514
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Publication
24194600 | J:228563
First Author: Koscielny G
Year: 2014
Journal: Nucleic Acids Res
Title: The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data.
Volume: 42
Issue: Database issue
Pages: D802-9
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Publication
- | J:204739
     
First Author: International Knockout Mouse Consortium
Year: 2014
Journal: Database Download
Title: MGI download of modified allele data from IKMC and creation of new knockout alleles
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Publication
- | J:204812
     
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
32323921 | J:294705
First Author: Oberhuber M
Year: 2020
Journal: Mol Syst Biol
Title: STAT3-dependent analysis reveals PDK4 as independent predictor of recurrence in prostate cancer.
Volume: 16
Issue: 4
Pages: e9247
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Publication
31562244 | J:283067
First Author: Newhardt MF
Year: 2019
Journal: J Biol Chem
Title: Enhancing cardiac glycolysis causes an increase in PDK4 content in response to short-term high-fat diet.
Volume: 294
Issue: 45
Pages: 16831-16845
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Publication
31930988 | J:292470
First Author: Gao Y
Year: 2020
Journal: Gastroenterology
Title: LKB1 Represses ATOH1 via PDK4 and Energy Metabolism and Regulates Intestinal Stem Cell Fate.
Volume: 158
Issue: 5
Pages: 1389-1401.e10
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UniProt Feature
UniProt Feature
Begin: 294
Description: Phosphoserine; by PDK1, PDK2, PDK3 and PDK4
Type: modified residue
End: 294
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UniProt Feature
UniProt Feature
Begin: 293
Description: Phosphoserine; by PDK1, PDK2, PDK3 and PDK4
Type: modified residue
End: 293
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UniProt Feature
UniProt Feature
Begin: 300
Description: Phosphoserine; by PDK1, PDK2, PDK3 and PDK4
Type: modified residue
End: 300
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Publication
21190881 | J:168464
First Author: Ushikai M
Year: 2011
Journal: Mol Genet Metab
Title: Induction of PDK4 in the heart muscle of JVS mice, an animal model of systemic carnitine deficiency, does not appear to reduce glucose utilization by the heart.
Volume: 102
Issue: 3
Pages: 349-55
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Allele
Pdk4<em1Smoc> | MGI:7291594
Name: pyruvate dehydrogenase kinase, isoenzyme 4; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Liu Z (2014)
Description: PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
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Publication
25164809 | -
First Author: Liu Z
Year: 2014
Journal: J Biol Chem
Title: PDK4 protein promotes tumorigenesis through activation of cAMP-response element-binding protein (CREB)-Ras homolog enriched in brain (RHEB)-mTORC1 signaling cascade.
Volume: 289
Issue: 43
Pages: 29739-49
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HT Experiment
E-GEOD-14984 | Neonatal starvation response and developmental changes in gene expression revealed by hypothalamic expression profiling
Series Id: GSE14984
Experiment Type: transcription profiling by array
Study Type: WT vs. Mutant
Source: ArrayExpress
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Publication
18083902 | J:132373
First Author: Zhao G
Year: 2008
Journal: Am J Physiol Heart Circ Physiol
Title: Overexpression of pyruvate dehydrogenase kinase 4 in heart perturbs metabolism and exacerbates calcineurin-induced cardiomyopathy.
Volume: 294
Issue: 2
Pages: H936-43
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Publication
10609898 | J:59784
First Author: Horiuchi M
Year: 1999
Journal: Biofactors
Title: Pyruvate dehydrogenase kinase 4 mRNA is increased in the hypertrophied ventricles of carnitine-deficient juvenile visceral steatosis (JVS) mice.
Volume: 10
Issue: 2-3
Pages: 301-9
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Publication
24567902 | J:221294
First Author: Dyar KA
Year: 2014
Journal: Mol Metab
Title: Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock.
Volume: 3
Issue: 1
Pages: 29-41
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Publication
17669420 | J:166353
First Author: Degenhardt T
Year: 2007
Journal: J Mol Biol
Title: Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta.
Volume: 372
Issue: 2
Pages: 341-55
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Publication
21321124 | J:170902
First Author: Chambers KT
Year: 2011
Journal: J Biol Chem
Title: Chronic inhibition of pyruvate dehydrogenase in heart triggers an adaptive metabolic response.
Volume: 286
Issue: 13
Pages: 11155-62
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Publication
21897366 | J:180033
First Author: Morita M
Year: 2011
Journal: EMBO J
Title: Obesity resistance and increased hepatic expression of catabolism-related mRNAs in Cnot3+/- mice.
Volume: 30
Issue: 22
Pages: 4678-91
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Publication
30232375 | J:277727
First Author: Gherardi G
Year: 2019
Journal: Cell Death Differ
Title: Loss of mitochondrial calcium uniporter rewires skeletal muscle metabolism and substrate preference.
Volume: 26
Issue: 2
Pages: 362-381
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Publication
24186946 | J:204194
First Author: Wongsiriroj N
Year: 2014
Journal: J Lipid Res
Title: Genetic dissection of retinoid esterification and accumulation in the liver and adipose tissue.
Volume: 55
Issue: 1
Pages: 104-14
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Publication
25145386 | J:217834
First Author: Imamura M
Year: 2014
Journal: Biochem J
Title: MondoA deficiency enhances sprint performance in mice.
Volume: 464
Issue: 1
Pages: 35-48
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Publication
21625432 | J:172724
First Author: Palomer X
Year: 2011
Journal: PLoS One
Title: The interplay between NF-kappaB and E2F1 coordinately regulates inflammation and metabolism in human cardiac cells.
Volume: 6
Issue: 5
Pages: e19724
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Publication
21081708 | J:172321
First Author: Wei D
Year: 2011
Journal: Am J Physiol Endocrinol Metab
Title: Feedback regulation of hepatic gluconeogenesis through modulation of SHP/Nr0b2 gene expression by Sirt1 and FoxO1.
Volume: 300
Issue: 2
Pages: E312-20
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Publication
29610263 | J:262215
First Author: Rohm M
Year: 2018
Journal: Diabetes
Title: Cardiac Dysfunction and Metabolic Inflexibility in a Mouse Model of Diabetes Without Dyslipidemia.
Volume: 67
Issue: 6
Pages: 1057-1067
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Publication
32617517 | J:295192
First Author: Cardoso AC
Year: 2020
Journal: Nat Metab
Title: Mitochondrial Substrate Utilization Regulates Cardiomyocyte Cell Cycle Progression.
Volume: 2
Issue: 2
Pages: 167-178
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Publication
12023878 | J:113527
First Author: Sugden MC
Year: 2002
Journal: Biochem J
Title: Peroxisome-proliferator-activated receptor-alpha (PPARalpha) deficiency leads to dysregulation of hepatic lipid and carbohydrate metabolism by fatty acids and insulin.
Volume: 364
Issue: Pt 2
Pages: 361-8
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Publication
11697863 | J:72837
First Author: Sugden MC
Year: 2001
Journal: Arch Biochem Biophys
Title: Role of peroxisome proliferator-activated receptor-alpha in the mechanism underlying changes in renal pyruvate dehydrogenase kinase isoform 4 protein expression in starvation and after refeeding.
Volume: 395
Issue: 2
Pages: 246-52
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Publication
28659287 | J:244132
First Author: Dragos SM
Year: 2017
Journal: Am J Physiol Cell Physiol
Title: Reduced SCD1 activity alters markers of fatty acid reesterification, glyceroneogenesis, and lipolysis in murine white adipose tissue and 3T3-L1 adipocytes.
Volume: 313
Issue: 3
Pages: C295-C304
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Publication
23066095 | J:200256
First Author: Shin DJ
Year: 2012
Journal: Nucleic Acids Res
Title: Genome-wide analysis of FoxO1 binding in hepatic chromatin: potential involvement of FoxO1 in linking retinoid signaling to hepatic gluconeogenesis.
Volume: 40
Issue: 22
Pages: 11499-509
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Publication
19690166 | J:157816
First Author: Xie YB
Year: 2009
Journal: J Biol Chem
Title: Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation.
Volume: 284
Issue: 42
Pages: 28762-74
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Publication
18566121 | J:141767
First Author: Colin S
Year: 2008
Journal: Endocrinology
Title: Intestine-specific regulation of PPARalpha gene transcription by liver X receptors.
Volume: 149
Issue: 10
Pages: 5128-35
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Publication
22058168 | J:318948
First Author: Matsakas A
Year: 2012
Journal: Exp Physiol
Title: Exercise training attenuates the hypermuscular phenotype and restores skeletal muscle function in the myostatin null mouse.
Volume: 97
Issue: 1
Pages: 125-40
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Publication
36980540 | J:334471
 
First Author: Woolbright BL
Year: 2023
Journal: Cancers (Basel)
Title: Pyruvate Dehydrogenase Kinase 4 Deficiency Increases Tumorigenesis in a Murine Model of Bladder Cancer.
Volume: 15
Issue: 6
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Publication
37699967 | J:340574
First Author: Del Gaudio F
Year: 2023
Journal: Sci Rep
Title: Left ventricular hypertrophy and metabolic resetting in the Notch3-deficient adult mouse heart.
Volume: 13
Issue: 1
Pages: 15022
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Publication
21411764 | J:172411
First Author: Dunford EC
Year: 2011
Journal: Am J Physiol Regul Integr Comp Physiol
Title: PDH activation during in vitro muscle contractions in PDH kinase 2 knockout mice: effect of PDH kinase 1 compensation.
Volume: 300
Issue: 6
Pages: R1487-93
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Publication
28028037 | J:244203
First Author: Gudiksen A
Year: 2017
Journal: Am J Physiol Endocrinol Metab
Title: Muscle interleukin-6 and fasting-induced PDH regulation in mouse skeletal muscle.
Volume: 312
Issue: 3
Pages: E204-E214
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Publication
28182733 | J:245919
First Author: Halvarsson C
Year: 2017
Journal: PLoS One
Title: Pyruvate dehydrogenase kinase 1 is essential for transplantable mouse bone marrow hematopoietic stem cell and progenitor function.
Volume: 12
Issue: 2
Pages: e0171714
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Publication
20720174 | J:165597
First Author: Kiilerich K
Year: 2010
Journal: Am J Physiol Regul Integr Comp Physiol
Title: PGC-1alpha increases PDH content but does not change acute PDH regulation in mouse skeletal muscle.
Volume: 299
Issue: 5
Pages: R1350-9
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Publication
20638986 | J:163280
First Author: Song S
Year: 2010
Journal: Mol Cell Endocrinol
Title: Peroxisome proliferator activated receptor alpha (PPARalpha) and PPAR gamma coactivator (PGC-1alpha) induce carnitine palmitoyltransferase IA (CPT-1A) via independent gene elements.
Volume: 325
Issue: 1-2
Pages: 54-63
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Publication
21609322 | J:175395
First Author: Caton PW
Year: 2011
Journal: Biochem J
Title: PPARα-LXR as a novel metabolostatic signalling axis in skeletal muscle that acts to optimize substrate selection in response to nutrient status.
Volume: 437
Issue: 3
Pages: 521-30
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Publication
32881962 | J:296039
First Author: Tanaka K
Year: 2020
Journal: PLoS One
Title: Difference in pyruvic acid metabolism between neonatal and adult mouse lungs exposed to hyperoxia.
Volume: 15
Issue: 9
Pages: e0238604
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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