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Search results 101 to 200 out of 2711 for Apc

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Category: Publication
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Type Details Score
Publication
18056448 | J:128481
First Author: Wang H
Year: 2007
Journal: Cancer Res
Title: Identification of novel modifier loci of Apc Min affecting mammary tumor development.
Volume: 67
Issue: 23
Pages: 11226-33
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Publication
16340248 | J:106940
First Author: Busquets L
Year: 2006
Journal: Tumour Biol
Title: Cathepsin E is a specific marker of dysplasia in APC mouse intestine.
Volume: 27
Issue: 1
Pages: 36-42
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Publication
8563176 | J:29386
First Author: Toyota M
Year: 1995
Journal: Mamm Genome
Title: cDNA cloning of the rat APC gene and assignment to chromosome 18.
Volume: 6
Issue: 10
Pages: 746-8
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Publication
28057861 | J:239530
First Author: Hashimoto K
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Cellular context-dependent consequences of Apc mutations on gene regulation and cellular behavior.
Volume: 114
Issue: 4
Pages: 758-763
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Publication
26146642 | J:316516
 
First Author: Chae WJ
Year: 2015
Journal: J Immunol Res
Title: Spontaneous Intestinal Tumorigenesis in Apc (/Min+) Mice Requires Altered T Cell Development with IL-17A.
Volume: 2015
Pages: 860106
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Publication
33930605 | J:314240
First Author: Murray E
Year: 2021
Journal: Cell Mol Gastroenterol Hepatol
Title: HER2 and APC Mutations Promote Altered Crypt-Villus Morphology and Marked Hyperplasia in the Intestinal Epithelium.
Volume: 12
Issue: 3
Pages: 1105-1120
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Publication
20736363 | J:165592
First Author: Cole AM
Year: 2010
Journal: Cancer Res
Title: Cyclin D2-cyclin-dependent kinase 4/6 is required for efficient proliferation and tumorigenesis following Apc loss.
Volume: 70
Issue: 20
Pages: 8149-58
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Publication
10027409 | J:52818
First Author: Wielenga VJ
Year: 1999
Journal: Am J Pathol
Title: Expression of CD44 in Apc and Tcf mutant mice implies regulation by the WNT pathway.
Volume: 154
Issue: 2
Pages: 515-23
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Publication
15210940 | J:91411
First Author: Haigis KM
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: Tumor regionality in the mouse intestine reflects the mechanism of loss of Apc function.
Volume: 101
Issue: 26
Pages: 9769-73
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Publication
11126362 | J:67119
First Author: Kuraguchi M
Year: 2000
Journal: Oncogene
Title: Tumor-associated Apc mutations in Mlh1-/- Apc1638N mice reveal a mutational signature of Mlh1 deficiency.
Volume: 19
Issue: 50
Pages: 5755-63
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Publication
21363919 | J:169671
First Author: Tanwar PS
Year: 2011
Journal: Cancer Res
Title: Stromal deletion of the APC tumor suppressor in mice triggers development of endometrial cancer.
Volume: 71
Issue: 5
Pages: 1584-96
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Publication
28086833 | J:309025
First Author: Badenes M
Year: 2017
Journal: BMC Cancer
Title: Delta-like 4/Notch signaling promotes Apc Min/+ tumor initiation through angiogenic and non-angiogenic related mechanisms.
Volume: 17
Issue: 1
Pages: 50
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Publication
8631000 | J:79095
First Author: Jacoby RF
Year: 1996
Journal: Cancer Res
Title: Chemoprevention of spontaneous intestinal adenomas in the Apc Min mouse model by the nonsteroidal anti-inflammatory drug piroxicam.
Volume: 56
Issue: 4
Pages: 710-4
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Publication
8415640 | J:15101
First Author: Moser AR
Year: 1993
Journal: Proc Natl Acad Sci U S A
Title: ApcMin, a mutation in the murine Apc gene, predisposes to mammary carcinomas and focal alveolar hyperplasias.
Volume: 90
Issue: 19
Pages: 8977-81
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Publication
12384562 | J:79668
First Author: Hamamoto T
Year: 2002
Journal: Cancer Res
Title: Compound disruption of smad2 accelerates malignant progression of intestinal tumors in apc knockout mice.
Volume: 62
Issue: 20
Pages: 5955-61
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Publication
16478791 | J:106576
First Author: Park KS
Year: 2006
Journal: J Cell Sci
Title: APC inhibits ERK pathway activation and cellular proliferation induced by RAS.
Volume: 119
Issue: Pt 5
Pages: 819-27
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Publication
29041928 | J:271935
First Author: Ono J
Year: 2017
Journal: J Biomed Sci
Title: The TLR3/TICAM-1 signal constitutively controls spontaneous polyposis through suppression of c-Myc in Apc Min/+ mice.
Volume: 24
Issue: 1
Pages: 79
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Publication
12096346 | J:77981
First Author: Cullingworth J
Year: 2002
Journal: Oncogene
Title: Carcinogen-induced pancreatic lesions in the mouse: effect of Smad4 and Apc genotypes.
Volume: 21
Issue: 30
Pages: 4696-701
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Publication
19429790 | J:149542
First Author: Wang XP
Year: 2009
Journal: Development
Title: Apc inhibition of Wnt signaling regulates supernumerary tooth formation during embryogenesis and throughout adulthood.
Volume: 136
Issue: 11
Pages: 1939-49
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Publication
12645927 | J:81402
First Author: Ishikawa TO
Year: 2003
Journal: Dev Biol
Title: Requirement for tumor suppressor Apc in the morphogenesis of anterior and ventral mouse embryo.
Volume: 253
Issue: 2
Pages: 230-46
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Publication
9506519 | J:46242
First Author: Takaku K
Year: 1998
Journal: Cell
Title: Intestinal tumorigenesis in compound mutant mice of both Dpc4 (Smad4) and Apc genes.
Volume: 92
Issue: 5
Pages: 645-56
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Publication
21664244 | J:183739
First Author: Wang Y
Year: 2011
Journal: Mol Cell Endocrinol
Title: Loss of APC function in mesenchymal cells surrounding the Müllerian duct leads to myometrial defects in adult mice.
Volume: 341
Issue: 1-2
Pages: 48-54
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Publication
12226748 | J:79068
First Author: Gallagher RC
Year: 2002
Journal: Oncogene
Title: Inactivation of Apc perturbs mammary development, but only directly results in acanthoma in the context of Tcf-1 deficiency.
Volume: 21
Issue: 42
Pages: 6446-57
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Publication
17596282 | J:124123
First Author: Strom A
Year: 2007
Journal: Development
Title: Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas.
Volume: 134
Issue: 15
Pages: 2719-25
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Publication
31291912 | J:290978
First Author: Mohamed NE
Year: 2019
Journal: BMC Cancer
Title: APC2 is critical for ovarian WNT signalling control, fertility and tumour suppression.
Volume: 19
Issue: 1
Pages: 677
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Publication
23646120 | J:221024
First Author: Li A
Year: 2013
Journal: PLoS One
Title: Tissue-dependent consequences of Apc inactivation on proliferation and differentiation of ciliated cell progenitors via Wnt and notch signaling.
Volume: 8
Issue: 4
Pages: e62215
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28729694 | J:253699
First Author: Hull MA
Year: 2017
Journal: Sci Rep
Title: Paracrine cyclooxygenase-2 activity by macrophages drives colorectal adenoma progression in the Apc Min/+ mouse model of intestinal tumorigenesis.
Volume: 7
Issue: 1
Pages: 6074
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Publication
12663524 | J:82832
First Author: Yang K
Year: 2003
Journal: Carcinogenesis
Title: Regional response leading to tumorigenesis after sulindac in small and large intestine of mice with Apc mutations.
Volume: 24
Issue: 3
Pages: 605-11
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Publication
26493106 | J:250659
First Author: Ye B
Year: 2015
Journal: J Mol Cell Cardiol
Title: APC controls asymmetric Wnt/β-catenin signaling and cardiomyocyte proliferation gradient in the heart.
Volume: 89
Issue: Pt B
Pages: 287-96
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Publication
12086850 | J:77135
First Author: Philipp-Staheli J
Year: 2002
Journal: Cancer Cell
Title: Pathway-specific tumor suppression. Reduction of p27 accelerates gastrointestinal tumorigenesis in Apc mutant mice, but not in Smad3 mutant mice.
Volume: 1
Issue: 4
Pages: 355-68
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Publication
32213541 | J:288817
First Author: Bruschi M
Year: 2020
Journal: Cancer Res
Title: Loss of Apc Rapidly Impairs DNA Methylation Programs and Cell Fate Decisions in Lgr5+ Intestinal Stem Cells.
Volume: 80
Issue: 11
Pages: 2101-2113
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23562608 | J:198191
First Author: Li C
Year: 2013
Journal: Dev Biol
Title: Apc deficiency alters pulmonary epithelial cell fate and inhibits Nkx2.1 via triggering TGF-beta signaling.
Volume: 378
Issue: 1
Pages: 13-24
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21996741 | J:186132
First Author: Zeineldin M
Year: 2012
Journal: Oncogene
Title: A knock-in mouse model reveals roles for nuclear Apc in cell proliferation, Wnt signal inhibition and tumor suppression.
Volume: 31
Issue: 19
Pages: 2423-37
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10766173 | J:61461
First Author: Jacoby RF
Year: 2000
Journal: Cancer Res
Title: Chemopreventive efficacy of combined piroxicam and difluoromethylornithine treatment of Apc mutant Min mouse adenomas, and selective toxicity against Apc mutant embryos.
Volume: 60
Issue: 7
Pages: 1864-70
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18794118 | J:141219
First Author: Yang K
Year: 2008
Journal: Cancer Res
Title: Interaction of Muc2 and Apc on Wnt signaling and in intestinal tumorigenesis: potential role of chronic inflammation.
Volume: 68
Issue: 18
Pages: 7313-22
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24320611 | J:210498
First Author: Hare LM
Year: 2014
Journal: Biochem J
Title: Physiological expression of the PI3K-activating mutation Pik3ca(H1047R) combines with Apc loss to promote development of invasive intestinal adenocarcinomas in mice.
Volume: 458
Issue: 2
Pages: 251-8
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Publication
17047044 | J:114960
First Author: Muñoz NM
Year: 2006
Journal: Cancer Res
Title: Transforming growth factor beta receptor type II inactivation induces the malignant transformation of intestinal neoplasms initiated by Apc mutation.
Volume: 66
Issue: 20
Pages: 9837-44
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34520730 | J:332942
First Author: Vu T
Year: 2022
Journal: Gastroenterology
Title: Serine-threonine Kinase Receptor-Associated Protein is a Critical Mediator of APC Mutation-Induced Intestinal Tumorigenesis Through a Feed-Forward Mechanism.
Volume: 162
Issue: 1
Pages: 193-208
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17227893 | J:119076
First Author: Dikovskaya D
Year: 2007
Journal: J Cell Biol
Title: Loss of APC induces polyploidy as a result of a combination of defects in mitosis and apoptosis.
Volume: 176
Issue: 2
Pages: 183-95
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7478622 | J:29664
First Author: Clarke AR
Year: 1995
Journal: Oncogene
Title: Interaction between murine germline mutations in p53 and APC predisposes to pancreatic neoplasia but not to increased intestinal malignancy.
Volume: 11
Issue: 9
Pages: 1913-20
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18723878 | J:139675
First Author: Halberg RB
Year: 2008
Journal: Genetics
Title: The pleiotropic phenotype of Apc mutations in the mouse: allele specificity and effects of the genetic background.
Volume: 180
Issue: 1
Pages: 601-9
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Publication
20696900 | J:221027
First Author: Poulogiannis G
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: PARK2 deletions occur frequently in sporadic colorectal cancer and accelerate adenoma development in Apc mutant mice.
Volume: 107
Issue: 34
Pages: 15145-50
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19420017 | J:150681
First Author: Koelink PJ
Year: 2009
Journal: Carcinogenesis
Title: 5-Aminosalicylic acid inhibits colitis-associated but not sporadic colorectal neoplasia in a novel conditional Apc mouse model.
Volume: 30
Issue: 7
Pages: 1217-24
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Publication
32792685 | J:296235
First Author: Reischmann N
Year: 2020
Journal: Oncogene
Title: BRAFV600E drives dedifferentiation in small intestinal and colonic organoids and cooperates with mutant p53 and Apc loss in transformation.
Volume: 39
Issue: 38
Pages: 6053-6070
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32586050 | J:305914
 
First Author: Hsieh MJ
Year: 2020
Journal: Int J Mol Sci
Title: Inactivation of APC Induces CD34 Upregulation to Promote Epithelial-Mesenchymal Transition and Cancer Stem Cell Traits in Pancreatic Cancer.
Volume: 21
Issue: 12
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Publication
19033191 | J:142249
First Author: Reed KR
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: B-catenin deficiency, but not Myc deletion, suppresses the immediate phenotypes of APC loss in the liver.
Volume: 105
Issue: 48
Pages: 18919-23
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20442768 | J:160564
First Author: Labalette C
Year: 2010
Journal: PLoS One
Title: Deficiency of the LIM-only protein FHL2 reduces intestinal tumorigenesis in Apc mutant mice.
Volume: 5
Issue: 4
Pages: e10371
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20976827 | J:294141
First Author: Cole AM
Year: 2010
Journal: EMBO Mol Med
Title: p21 loss blocks senescence following Apc loss and provokes tumourigenesis in the renal but not the intestinal epithelium.
Volume: 2
Issue: 11
Pages: 472-86
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26411367 | J:234310
First Author: Kuo TL
Year: 2016
Journal: Oncogene
Title: APC haploinsufficiency coupled with p53 loss sufficiently induces mucinous cystic neoplasms and invasive pancreatic carcinoma in mice.
Volume: 35
Issue: 17
Pages: 2223-34
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20729907 | J:166564
First Author: Radulescu S
Year: 2010
Journal: Oncogene
Title: Defining the role of APC in the mitotic spindle checkpoint in vivo: APC-deficient cells are resistant to Taxol.
Volume: 29
Issue: 49
Pages: 6418-27
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19194513 | J:146495
First Author: Elahi E
Year: 2009
Journal: PLoS One
Title: Five quantitative trait loci control radiation-induced adenoma multiplicity in Mom1R Apc Min/+ mice.
Volume: 4
Issue: 2
Pages: e4388
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29672847 | J:265573
First Author: Morris HT
Year: 2018
Journal: J Pathol
Title: Loss of N-WASP drives early progression in an Apc model of intestinal tumourigenesis.
Volume: 245
Issue: 3
Pages: 337-348
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22893683 | J:189809
First Author: Shaked H
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation.
Volume: 109
Issue: 35
Pages: 14007-12
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21498506 | -
First Author: Tanneberger K
Year: 2011
Journal: J Biol Chem
Title: Structural and functional characterization of the Wnt inhibitor APC membrane recruitment 1 (Amer1).
Volume: 286
Issue: 22
Pages: 19204-14
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11729120 | J:72879
First Author: Cooper HS
Year: 2001
Journal: Gastroenterology
Title: The role of mutant Apc in the development of dysplasia and cancer in the mouse model of dextran sulfate sodium-induced colitis.
Volume: 121
Issue: 6
Pages: 1407-16
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16959882 | J:113749
First Author: Sansom OJ
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Loss of Apc allows phenotypic manifestation of the transforming properties of an endogenous K-ras oncogene in vivo.
Volume: 103
Issue: 38
Pages: 14122-7
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10602475 | J:59017
First Author: Kongkanuntn R
Year: 1999
Journal: Oncogene
Title: Dysregulated expression of beta-catenin marks early neoplastic change in Apc mutant mice, but not all lesions arising in Msh2 deficient mice.
Volume: 18
Issue: 51
Pages: 7219-25
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26527747 | J:316572
First Author: Bae JA
Year: 2016
Journal: Clin Cancer Res
Title: Elevated Coexpression of KITENIN and the ErbB4 CYT-2 Isoform Promotes the Transition from Colon Adenoma to Carcinoma Following APC loss.
Volume: 22
Issue: 5
Pages: 1284-94
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19515997 | J:154534
First Author: Martinez G
Year: 2009
Journal: Invest Ophthalmol Vis Sci
Title: Conditional mutations of beta-catenin and APC reveal roles for canonical Wnt signaling in lens differentiation.
Volume: 50
Issue: 10
Pages: 4794-806
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30721564 | J:294462
First Author: Sartor C
Year: 2019
Journal: Liver Int
Title: The concomitant loss of APC and HNF4α in adult hepatocytes does not contribute to hepatocarcinogenesis driven by β-catenin activation.
Volume: 39
Issue: 4
Pages: 727-739
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15294912 | J:94014
First Author: Moran AE
Year: 2004
Journal: J Biol Chem
Title: Apc deficiency is associated with increased Egfr activity in the intestinal enterocytes and adenomas of C57BL/6J-Min/+ mice.
Volume: 279
Issue: 41
Pages: 43261-72
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23998936 | J:211367
First Author: Hammoudi A
Year: 2013
Journal: Biochem Biophys Res Commun
Title: Proteomic profiling of a mouse model of acute intestinal Apc deletion leads to identification of potential novel biomarkers of human colorectal cancer (CRC).
Volume: 440
Issue: 3
Pages: 364-70
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24833705 | J:221729
First Author: Powell AE
Year: 2014
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Inducible loss of one Apc allele in Lrig1-expressing progenitor cells results in multiple distal colonic tumors with features of familial adenomatous polyposis.
Volume: 307
Issue: 1
Pages: G16-23
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9307281 | J:42733
First Author: Fox JG
Year: 1997
Journal: Cancer Res
Title: Mice carrying a truncated Apc gene have diminished gastric epithelial proliferation, gastric inflammation, and humoral immunity in response to Helicobacter felis infection.
Volume: 57
Issue: 18
Pages: 3972-8
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12034317 | J:77184
First Author: Andreassen A
Year: 2002
Journal: Mutat Res
Title: One dose of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) or 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) induces tumours in Min/+ mice by truncation mutations or LOH in the Apc gene.
Volume: 517
Issue: 1-2
Pages: 157-66
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22303319 | J:309622
 
First Author: McKay JA
Year: 2011
Journal: Front Genet
Title: Effect of maternal and post-weaning folate supply on gene-specific DNA methylation in the small intestine of weaning and adult apc and wild type mice.
Volume: 2
Pages: 23
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23769888 | J:199069
First Author: Feng Y
Year: 2013
Journal: Am J Pathol
Title: Sox9 induction, ectopic Paneth cells, and mitotic spindle axis defects in mouse colon adenomatous epithelium arising from conditional biallelic Apc inactivation.
Volume: 183
Issue: 2
Pages: 493-503
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11691815 | J:73030
First Author: Kuraguchi M
Year: 2001
Journal: Cancer Res
Title: The distinct spectra of tumor-associated Apc mutations in mismatch repair-deficient Apc1638N mice define the roles of MSH3 and MSH6 in DNA repair and intestinal tumorigenesis.
Volume: 61
Issue: 21
Pages: 7934-42
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21062985 | J:166853
First Author: Diegel CR
Year: 2010
Journal: Cancer Res
Title: Mammalian target of rapamycin-dependent acinar cell neoplasia after inactivation of Apc and Pten in the mouse salivary gland: implications for human acinic cell carcinoma.
Volume: 70
Issue: 22
Pages: 9143-52
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9054624 | J:39174
First Author: Smits R
Year: 1997
Journal: Carcinogenesis
Title: Loss of Apc and the entire chromosome 18 but absence of mutations at the Ras and Tp53 genes in intestinal tumors from Apc1638N, a mouse model for Apc-driven carcinogenesis.
Volume: 18
Issue: 2
Pages: 321-7
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24890436 | J:217020
First Author: Rebel H
Year: 2015
Journal: Int J Cancer
Title: UV exposure inhibits intestinal tumor growth and progression to malignancy in intestine-specific Apc mutant mice kept on low vitamin D diet.
Volume: 136
Issue: 2
Pages: 271-7
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15567712 | J:94056
First Author: Murata T
Year: 2004
Journal: Gene Expr Patterns
Title: ang is a novel gene expressed in early neuroectoderm, but its null mutant exhibits no obvious phenotype.
Volume: 5
Issue: 2
Pages: 171-8
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17989230 | J:127452
First Author: Shibata H
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: Alpha-catenin is essential in intestinal adenoma formation.
Volume: 104
Issue: 46
Pages: 18199-204
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35947664 | J:327420
First Author: Chun SK
Year: 2022
Journal: Sci Adv
Title: Disruption of the circadian clock drives Apc loss of heterozygosity to accelerate colorectal cancer.
Volume: 8
Issue: 32
Pages: eabo2389
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29163805 | J:256596
First Author: Xu J
Year: 2017
Journal: Oncotarget
Title: Thymine DNA Glycosylase (TDG) is involved in the pathogenesis of intestinal tumors with reduced APC expression.
Volume: 8
Issue: 52
Pages: 89988-89997
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31736871 | J:289568
 
First Author: Counts BR
Year: 2019
Journal: Front Endocrinol (Lausanne)
Title: The Effect of Estradiol Administration on Muscle Mass Loss and Cachexia Progression in Female Apc Min/+ Mice.
Volume: 10
Pages: 720
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28351943 | J:317534
First Author: Tabrizian T
Year: 2017
Journal: Endocr Relat Cancer
Title: Apc inactivation, but not obesity, synergizes with Pten deficiency to drive intestinal stem cell-derived tumorigenesis.
Volume: 24
Issue: 6
Pages: 253-265
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26766442 | J:239972
First Author: Chiu CWN
Year: 2016
Journal: Dev Cell
Title: SAPCD2 Controls Spindle Orientation and Asymmetric Divisions by Negatively Regulating the Gαi-LGN-NuMA Ternary Complex.
Volume: 36
Issue: 1
Pages: 50-62
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30622113 | J:273229
First Author: Flanagan DJ
Year: 2019
Journal: Cancer Res
Title: Frizzled-7 Is Required for Wnt Signaling in Gastric Tumors with and Without Apc Mutations.
Volume: 79
Issue: 5
Pages: 970-981
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7781071 | J:26137
First Author: MacPhee M
Year: 1995
Journal: Cell
Title: The secretory phospholipase A2 gene is a candidate for the Mom1 locus, a major modifier of ApcMin-induced intestinal neoplasia.
Volume: 81
Issue: 6
Pages: 957-66
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8242739 | J:15703
First Author: Dietrich WF
Year: 1993
Journal: Cell
Title: Genetic identification of Mom-1, a major modifier locus affecting Min-induced intestinal neoplasia in the mouse.
Volume: 75
Issue: 4
Pages: 631-9
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10716720 | J:61200
First Author: Halberg RB
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Tumorigenesis in the multiple intestinal neoplasia mouse: redundancy of negative regulators and specificity of modifiers.
Volume: 97
Issue: 7
Pages: 3461-6
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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