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Search results 1 to 1 out of 1 for Cyp46a1

Category restricted to ProteinDomain (x)

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Category: ProteinDomain
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Type Details Score
Protein Domain
IPR039983 | CYP46A1
Type: Family
Description: Cholesterol 24-hydroxylase (CYP46A1) is the neuronal-specific and rate-limiting enzyme for cholesterol conversion to 24S-hydroxycholesterol (24S-OHC) [, ]. It has a neuroprotective effect in Huntington's disease, a genetic disease that leads to many cellular dysfunctions, including abnormalities in cholesterol metabolism [, ].
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