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Search results 1 to 67 out of 67 for Cyp46a1

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Category: Publication
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Type Details Score
Publication
10377398 | J:56019
First Author: Lund EG
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: cDNA cloning of cholesterol 24-hydroxylase, a mediator of cholesterol homeostasis in the brain.
Volume: 96
Issue: 13
Pages: 7238-43
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Publication
30107216 | J:268841
     
First Author: Boussicault L
Year: 2018
Journal: Biochimie
Title: CYP46A1 protects against NMDA-mediated excitotoxicity in Huntington's disease: Analysis of lipid raft content.
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Publication
31063705 | J:293734
First Author: Petrov AM
Year: 2019
Journal: FASEB J
Title: The key genes, phosphoproteins, processes, and pathways affected by efavirenz-activated CYP46A1 in the amyloid-decreasing paradigm of efavirenz treatment.
Volume: 33
Issue: 8
Pages: 8782-8798
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Publication
14764421 | -
First Author: Björkhem I
Year: 2004
Journal: Arterioscler Thromb Vasc Biol
Title: Brain cholesterol: long secret life behind a barrier.
Volume: 24
Issue: 5
Pages: 806-15
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Publication
26912634 | -
First Author: Boussicault L
Year: 2016
Journal: Brain
Title: CYP46A1, the rate-limiting enzyme for cholesterol degradation, is neuroprotective in Huntington's disease.
Volume: 139
Issue: Pt 3
Pages: 953-70
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Publication
25084760 | J:325345
First Author: Moutinho M
Year: 2015
Journal: Mol Neurobiol
Title: Cholesterol 24S-Hydroxylase Overexpression Inhibits the Liver X Receptor (LXR) Pathway by Activating Small Guanosine Triphosphate-Binding Proteins (sGTPases) in Neuronal Cells.
Volume: 51
Issue: 3
Pages: 1489-503
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Publication
28655608 | J:249708
 
First Author: Mast N
Year: 2017
Journal: Neuropharmacology
Title: Cholesterol-metabolizing enzyme cytochrome P450 46A1 as a pharmacologic target for Alzheimer's disease.
Volume: 123
Pages: 465-476
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Publication
29073233 | J:248888
First Author: Mast N
Year: 2017
Journal: PLoS One
Title: Transcriptional and post-translational changes in the brain of mice deficient in cholesterol removal mediated by cytochrome P450 46A1 (CYP46A1).
Volume: 12
Issue: 10
Pages: e0187168
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Publication
28190002 | J:241374
First Author: Mast N
Year: 2017
Journal: J Biol Chem
Title: Cytochrome P450 27A1 Deficiency and Regional Differences in Brain Sterol Metabolism Cause Preferential Cholestanol Accumulation in the Cerebellum.
Volume: 292
Issue: 12
Pages: 4913-4924
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Publication
30448403 | J:270474
First Author: Saadane A
Year: 2019
Journal: Am J Pathol
Title: Retinal Vascular Abnormalities and Microglia Activation in Mice with Deficiency in Cytochrome P450 46A1-Mediated Cholesterol Removal.
Volume: 189
Issue: 2
Pages: 405-425
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Publication
22343944 | J:182508
First Author: Sodero AO
Year: 2012
Journal: EMBO J
Title: Cholesterol loss during glutamate-mediated excitotoxicity.
Volume: 31
Issue: 7
Pages: 1764-73
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Publication
14643015 | J:86935
First Author: Quan G
Year: 2003
Journal: Brain Res Dev Brain Res
Title: Ontogenesis and regulation of cholesterol metabolism in the central nervous system of the mouse.
Volume: 146
Issue: 1-2
Pages: 87-98
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Publication
22111624 | J:196553
First Author: Lorbek G
Year: 2012
Journal: FEBS J
Title: Cytochrome P450s in the synthesis of cholesterol and bile acids--from mouse models to human diseases.
Volume: 279
Issue: 9
Pages: 1516-33
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Publication
18241055 | J:269548
First Author: Ramirez DM
Year: 2008
Journal: J Comp Neurol
Title: Neuronal expression and subcellular localization of cholesterol 24-hydroxylase in the mouse brain.
Volume: 507
Issue: 5
Pages: 1676-93
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19204288 | J:146447
First Author: Halford RW
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Reduction of cholesterol synthesis in the mouse brain does not affect amyloid formation in Alzheimer's disease, but does extend lifespan.
Volume: 106
Issue: 9
Pages: 3502-6
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12686551 | J:84116
First Author: Lund EG
Year: 2003
Journal: J Biol Chem
Title: Knockout of the cholesterol 24-hydroxylase gene in mice reveals a brain-specific mechanism of cholesterol turnover.
Volume: 278
Issue: 25
Pages: 22980-8
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Publication
24491562 | J:325508
First Author: Meljon A
Year: 2014
Journal: Biochem Biophys Res Commun
Title: Oxysterols in the brain of the cholesterol 24-hydroxylase knockout mouse.
Volume: 446
Issue: 3
Pages: 768-74
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28346482 | J:245999
First Author: Sun MY
Year: 2017
Journal: PLoS One
Title: 24S-hydroxycholesterol and 25-hydroxycholesterol differentially impact hippocampal neuronal survival following oxygen-glucose deprivation.
Volume: 12
Issue: 3
Pages: e0174416
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Publication
32132201 | J:286767
First Author: Yutuc E
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Localization of sterols and oxysterols in mouse brain reveals distinct spatial cholesterol metabolism.
Volume: 117
Issue: 11
Pages: 5749-5760
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33051477 | J:299048
First Author: Nishi T
Year: 2020
Journal: Sci Rep
Title: Soticlestat, a novel cholesterol 24-hydroxylase inhibitor shows a therapeutic potential for neural hyperexcitation in mice.
Volume: 10
Issue: 1
Pages: 17081
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12810827 | J:85795
First Author: Xie C
Year: 2003
Journal: J Lipid Res
Title: Quantitation of two pathways for cholesterol excretion from the brain in normal mice and mice with neurodegeneration.
Volume: 44
Issue: 9
Pages: 1780-9
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Publication
25065682 | J:213942
First Author: Saadane A
Year: 2014
Journal: Am J Pathol
Title: Retinal and nonocular abnormalities in Cyp27a1(-/-)Cyp46a1(-/-) mice with dysfunctional metabolism of cholesterol.
Volume: 184
Issue: 9
Pages: 2403-19
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16505352 | J:107142
First Author: Kotti TJ
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Brain cholesterol turnover required for geranylgeraniol production and learning in mice.
Volume: 103
Issue: 10
Pages: 3869-74
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27514747 | J:237041
First Author: Saadane A
Year: 2016
Journal: J Biol Chem
Title: Retinal Hypercholesterolemia Triggers Cholesterol Accumulation and Esterification in Photoreceptor Cells.
Volume: 291
Issue: 39
Pages: 20427-39
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18685105 | J:140342
First Author: Kotti T
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Biphasic requirement for geranylgeraniol in hippocampal long-term potentiation.
Volume: 105
Issue: 32
Pages: 11394-9
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20193040 | J:285001
First Author: Tian G
Year: 2010
Journal: J Neurochem
Title: Increased expression of cholesterol 24S-hydroxylase results in disruption of glial glutamate transporter EAAT2 association with lipid rafts: a potential role in Alzheimer's disease.
Volume: 113
Issue: 4
Pages: 978-89
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Publication
16651660 | J:112056
First Author: Tint GS
Year: 2006
Journal: J Lipid Res
Title: The use of the Dhcr7 knockout mouse to accurately determine the origin of fetal sterols.
Volume: 47
Issue: 7
Pages: 1535-41
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Publication
23892605 | J:198551
First Author: Buchovecky CM
Year: 2013
Journal: Nat Genet
Title: A suppressor screen in Mecp2 mutant mice implicates cholesterol metabolism in Rett syndrome.
Volume: 45
Issue: 9
Pages: 1013-20
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Publication
14697215 | J:87460
First Author: Togashi T
Year: 2004
Journal: Biochem Biophys Res Commun
Title: Two distinct methods analyzing chromatin structure using centrifugation and antibodies to modified histone H3: both provide similar chromatin states of the Rit1/Bcl11b gene.
Volume: 313
Issue: 3
Pages: 489-95
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Publication
25402856 | J:219376
First Author: La Fata G
Year: 2014
Journal: Nat Neurosci
Title: FMRP regulates multipolar to bipolar transition affecting neuronal migration and cortical circuitry.
Volume: 17
Issue: 12
Pages: 1693-700
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Publication
19633360 | J:157050
First Author: Bojanic DD
Year: 2010
Journal: J Lipid Res
Title: Differential expression and function of ABCG1 and ABCG4 during development and aging.
Volume: 51
Issue: 1
Pages: 169-81
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Publication
12745259 | J:83483
First Author: Choudhary D
Year: 2003
Journal: Arch Biochem Biophys
Title: Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.
Volume: 414
Issue: 1
Pages: 91-100
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Publication
- | J:342601
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniPathway vocabulary mapping
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Publication
15226823 | J:93300
First Author: Blackshaw S
Year: 2004
Journal: PLoS Biol
Title: Genomic analysis of mouse retinal development.
Volume: 2
Issue: 9
Pages: E247
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
16602821 | J:162220
First Author: Magdaleno S
Year: 2006
Journal: PLoS Biol
Title: BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system.
Volume: 4
Issue: 4
Pages: e86
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
37446179 | J:337897
 
First Author: Pinchaud K
Year: 2023
Journal: Int J Mol Sci
Title: Cell-Type Specific Regulation of Cholesterogenesis by CYP46A1 Re-Expression in zQ175 HD Mouse Striatum.
Volume: 24
Issue: 13
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38540675 | J:346698
 
First Author: Shu HJ
Year: 2024
Journal: Biomolecules
Title: Effects of Complete and Partial Loss of the 24S-Hydroxycholesterol-Generating Enzyme Cyp46a1 on Behavior and Hippocampal Transcription in Mouse.
Volume: 14
Issue: 3
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31535451 | J:293074
First Author: Mitroi DN
Year: 2019
Journal: EMBO Rep
Title: NPC1 enables cholesterol mobilization during long-term potentiation that can be restored in Niemann-Pick disease type C by CYP46A1 activation.
Volume: 20
Issue: 11
Pages: e48143
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35236834 | J:342927
First Author: Zhao Y
Year: 2022
Journal: Nat Commun
Title: ATAD3A oligomerization promotes neuropathology and cognitive deficits in Alzheimer's disease models.
Volume: 13
Issue: 1
Pages: 1121
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23874659 | J:204404
First Author: Maioli S
Year: 2013
Journal: PLoS One
Title: Is it possible to improve memory function by upregulation of the cholesterol 24S-hydroxylase (CYP46A1) in the brain?
Volume: 8
Issue: 7
Pages: e68534
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16321981 | J:108495
First Author: Ohyama Y
Year: 2006
Journal: J Biol Chem
Title: Studies on the transcriptional regulation of cholesterol 24-hydroxylase (CYP46A1): marked insensitivity toward different regulatory axes.
Volume: 281
Issue: 7
Pages: 3810-20
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26358780 | J:226491
First Author: Burlot MA
Year: 2015
Journal: Hum Mol Genet
Title: Cholesterol 24-hydroxylase defect is implicated in memory impairments associated with Alzheimer-like Tau pathology.
Volume: 24
Issue: 21
Pages: 5965-76
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35721135 | J:326117
 
First Author: El-Darzi N
Year: 2022
Journal: Front Pharmacol
Title: Low-Dose Anti-HIV Drug Efavirenz Mitigates Retinal Vascular Lesions in a Mouse Model of Alzheimer's Disease.
Volume: 13
Pages: 902254
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27622776 | J:239565
 
First Author: Pérez-Cañamás A
Year: 2016
Journal: Neurobiol Aging
Title: A diet enriched with plant sterols prevents the memory impairment induced by cholesterol loss in senescence-accelerated mice.
Volume: 48
Pages: 1-12
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