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Search results 201 to 219 out of 219 for Il27

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0.017s

Type

Details

Score

Publication

- | J:155721

First Author:	Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year:	2010
Journal:	Database Download
Title:	Consensus CDS project

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Publication

- | J:155221

First Author:	Mouse Genome Informatics
Year:	2010
Journal:	Database Release
Title:	Protein Ontology Association Load.

•

Publication

- | J:91388

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2005

Title:	Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations

•

Publication

- | J:144086

First Author:	Mouse Genome Informatics Scientific Curators
Year:	2009
Journal:	Database Download
Title:	Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform

•

Publication

- | J:262123

First Author:	Allen Institute for Brain Science
Year:	2004
Journal:	Allen Institute
Title:	Allen Brain Atlas: mouse riboprobes

•

Publication

35723626 | J:327180

First Author:	Aghayev T
Year:	2022
Journal:	Cancer Discov
Title:	IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma.
Volume:	12
Issue:	8
Pages:	1960-1983

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Allele

Il27<em2Smoc> | MGI:7290490

Name:	interleukin 27; endonuclease-mediated mutation 2, Shanghai Model Organisms Center
Allele Type:	Endonuclease-mediated
Attribute String:	Null/knockout

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Strain

MGI:6428966 | C57BL/6J-Il27<em2Smoc>/Smoc

Attribute String:

coisogenic, mutant strain, endonuclease-mediated mutation

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Publication

17294231 | -

First Author:	Batten M
Year:	2007
Journal:	J Mol Med (Berl)
Title:	The biology and therapeutic potential of interleukin 27.
Volume:	85
Issue:	7
Pages:	661-72

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Publication

17068156 | -

First Author:	Fakruddin JM
Year:	2007
Journal:	Blood
Title:	Noninfectious papilloma virus-like particles inhibit HIV-1 replication: implications for immune control of HIV-1 infection by IL-27.
Volume:	109
Issue:	5
Pages:	1841-9

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Publication

18191724 | -

First Author:	Feng XM
Year:	2007
Journal:	Hum Immunol
Title:	Interleukin-27 upregulates major histocompatibility complex class II expression in primary human endothelial cells through induction of major histocompatibility complex class II transactivator.
Volume:	68
Issue:	12
Pages:	965-72

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Protein Domain

IPR026207 | IL-27_alpha

Type:

Family

Description:

This entry represents IL27-A proteins (known as IL-30/IL27-p28). Interleukin-27 is a heterodimeric cytokine composed of two subunits; IL27-A (IL27-p28) and Epstein-Barr virus-induced gene 3 (EBI3, also known as IL-27B) []. IL27 is a cytokine with pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells []. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines such as IP-10/CXCL10 and MIG/CXCL9. In vein endothelial cells, it induces IRF1/interferon regulatory factor 1 and increase the expression of MHC class II transactivator/CIITA with resulting up-regulation of major histocompatibility complex class II. IL-27 also demonstrates antiviral activity with inhibitory properties on HIV-1 replivation [, ].

•

Protein

Q8K3I6

Organism:	Mus musculus/domesticus
Length:	234
Fragment?:	false

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Publication

23285134 | J:195752

First Author:	Rowse AL
Year:	2012
Journal:	PLoS One
Title:	Lithium controls central nervous system autoimmunity through modulation of IFN-γ signaling.
Volume:	7
Issue:	12
Pages:	e52658

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Publication

32376420 | J:299325

First Author:	Bockerstett KA
Year:	2020
Journal:	Cell Mol Gastroenterol Hepatol
Title:	Interleukin 27 Protects From Gastric Atrophy and Metaplasia During Chronic Autoimmune Gastritis.
Volume:	10
Issue:	3
Pages:	561-579

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Publication

32078636 | J:290666

First Author:	Mota EA
Year:	2020
Journal:	PLoS Negl Trop Dis
Title:	Epigenetic and parasitological parameters are modulated in EBi3-/- mice infected with Schistosoma mansoni.
Volume:	14
Issue:	2
Pages:	e0008080

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Publication

25497733 | J:219294

First Author:	Chitu V
Year:	2015
Journal:	Neurobiol Dis
Title:	Phenotypic characterization of a Csf1r haploinsufficient mouse model of adult-onset leukodystrophy with axonal spheroids and pigmented glia (ALSP).
Volume:	74

Pages:	219-28

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Publication

29066514 | J:253859

First Author:	Canale FP
Year:	2018
Journal:	Cancer Res
Title:	CD39 Expression Defines Cell Exhaustion in Tumor-Infiltrating CD8⁺ T Cells.
Volume:	78
Issue:	1
Pages:	115-128

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Publication

31917258 | J:287706

First Author:	Lavoie S
Year:	2020
Journal:	Gastroenterology
Title:	Expression of Free Fatty Acid Receptor 2 by Dendritic Cells Prevents Their Expression of Interleukin 27 and Is Required for Maintenance of Mucosal Barrier and Immune Response Against Colorectal Tumors in Mice.
Volume:	158
Issue:	5
Pages:	1359-1372.e9

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